School of Medicine

Research Output 1973 2020

2019

Analytical performance of a new automated chemiluminescent magnetic immunoassays for soluble PD-1, PD-L1, and CTLA-4 in human plasma

Goto, M., Chamoto, K., Higuchi, K., Yamashita, S., Noda, K., Iino, T., Miura, M., Yamasaki, T., Ogawa, O., Sonobe, M., Date, H., Hamanishi, J., Mandai, M., Tanaka, Y., Chikuma, S., Hatae, R., Muto, M., Minamiguchi, S., Minato, N. & Honjo, T., 2019 Dec 1, In : Scientific reports. 9, 1, 10144.

Research output: Contribution to journalArticle

Open Access
Immunoassay
Neoplasms
Biomarkers
Immunotherapy
Enzyme-Linked Immunosorbent Assay

An application of artificial intelligence to diagnostic imaging of spine disease: Estimating spinal alignment from moiré images

Watanabe, K., Aoki, Y. & Matsumoto, M., 2019 Dec, In : Neurospine. 16, 4, p. 697-702 6 p.

Research output: Contribution to journalReview article

Open Access
Spinal Diseases
Artificial Intelligence
Scoliosis
Diagnostic Imaging
Spine

A nationwide questionnaire survey of clinic doctors on antimicrobial stewardship in Japan

Gu, Y., Fujitomo, Y., Soeda, H., Nakahama, C., Hasegawa, N., Maesaki, S., Maeda, M., Matsumoto, T., Miyairi, I. & Ohmagari, N., 2019 Jan 1, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Japan
Common Cold
Bronchitis
Macrolides
Prescriptions
1 Citation (Scopus)

Anatomical and surgical evaluation of the common marmoset as an animal model in hearing research

Kurihara, S., Fujioka, M., Hata, J., Yoshida, T., Hirabayashi, M., Yamamoto, Y., Ogawa, K., Kojima, H. & Okano, H. J., 2019 Jun 3, In : Frontiers in Neuroanatomy. 13, 60.

Research output: Contribution to journalArticle

Open Access
Callithrix
Inner Ear
Hearing
Animal Models
Diffusion Tensor Imaging

An effective detachment system for human induced pluripotent stem cells cultured on multilayered cultivation substrates using resonance vibrations

Terao, Y., Kurashina, Y., Tohyama, S., Fukuma, Y., Fukuda, K., Fujita, J. & Takemura, K., 2019 Dec 1, In : Scientific reports. 9, 1, 15655.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Vibration
Karyotype
Enzymes

A neonatal case of HDR syndrome and a vascular ring with a novel GATA3 mutation

Kusakawa, M., Sato, T., Hosoda, A., Araki, E., Matsuzaki, Y., Yamashita, Y., Ishihara, J., Inagaki, Y., Uchida, N., Ishii, T. & Hasegawa, T., 2019 Dec 1, In : Human Genome Variation. 6, 1, 55.

Research output: Contribution to journalArticle

Open Access
Blood Vessels
Genes
Mutation
Genetic Databases
Haploinsufficiency

A new training method for velopharyngeal dysfunction: Self-inhalation for hypernasality

Kobayashi, R., Tsunoda, K., Takazawa, M., Ueha, R., Hosoya, M., Fujimaki, Y., Nito, T. & Yamasoba, T., 2019 Jan 1, (Accepted/In press) In : Auris Nasus Larynx.

Research output: Contribution to journalArticle

Nose
Inhalation
Surgical Instruments
Rehabilitation
Dysarthria

An internal distraction device for midface distraction osteogenesis: The NAVID system type Z'gok

Sakamoto, Y., Sakamoto, T., Ishii, T. & Kishi, K., 2019 Jan 1, (Accepted/In press) In : Journal of Plastic, Reconstructive and Aesthetic Surgery.

Research output: Contribution to journalArticle

Distraction Osteogenesis
Equipment and Supplies
Control Groups
Craniosynostoses
Hoof and Claw

Annual report of Reproductive Endocrinology Committee, Japan Society of Obstetrics and Gynecology, 2019

Osuga, Y., Akira, S., Irahara, M., Iwase, A., Katagiri, Y., Kugu, K., Terada, Y., Maruyama, T. & Fujiwara, H., 2019 Jan 1, (Accepted/In press) In : Journal of Obstetrics and Gynaecology Research.

Research output: Contribution to journalArticle

Annual Reports
Endocrinology
Gynecology
Obstetrics
Fertility

A nonepidermolytic keratinocytic epidermal naevus associated with a postzygotic mutation in the gene encoding epidermal growth factor receptor

Umegaki-Arao, N., Ono, N., Tanaka, R., Sasaki, T., Fujita, H., Shiohama, A., Aoki, S., Amagai, M. & Kubo, A., 2019 Jan 1, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalLetter

1 Citation (Scopus)

A novel cell-free, non-fluorescent method to measure lox-1-binding activity corresponding to the functional activity of hdl

Kakino, A., Usami, Y., Horiuchi, S., Fujita, Y., Kotani, K., Chen, C. H., Okamura, T. & Sawamura, T., 2019 Jan 1, In : Journal of atherosclerosis and thrombosis. 26, 11, p. 947-958 12 p.

Research output: Contribution to journalArticle

Open Access
HDL Lipoproteins
Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Fusion reactions
Four-Dimensional Computed Tomography
Veins
Brain
Digital Subtraction Angiography
Intracranial Aneurysm
2 Citations (Scopus)

A Novel HIF Inhibitor Halofuginone Prevents Neurodegeneration in a Murine Model of Retinal Ischemia-Reperfusion

Kunimi, H., Miwa, Y., Inoue, H., Tsubota, K. & Kurihara, T., 2019 Jun 28, In : International journal of molecular sciences. 20, 13

Research output: Contribution to journalArticle

Open Access
ischemia
hypoxia
inhibitors
Reperfusion
Screening

A Novel Laser Fiberscope for Simultaneous Imaging and Phototherapy of Peripheral Lung Cancer

Kinoshita, T., Effat, A., Gregor, A., Inage, T., Ishiwata, T., Motooka, Y., Ujiie, H., Wilson, B. C., Zheng, G., Weersink, R., Asamura, H. & Yasufuku, K., 2019 Jan 1, In : Chest.

Research output: Contribution to journalArticle

Phototherapy
Lung Neoplasms
Lasers
Therapeutics
Bronchoscopes

A novel missense PTEN mutation identified in a patient with macrocephaly and developmental delay

Ueno, Y., Enokizono, T., Fukushima, H., Ohto, T., Imagawa, K., Tanaka, M., Sakai, A., Suzuki, H., Uehara, T., Takenouchi, T., Kosaki, K. & Takada, H., 2019 Dec 1, In : Human Genome Variation. 6, 1, 25.

Research output: Contribution to journalArticle

Open Access
Megalencephaly
Phosphoric Monoester Hydrolases
Multiple Hamartoma Syndrome
Mutation
Tumors
Open Access
Motor Vehicles
Emergencies
Surgery
laparotomy
Thoracotomy
2 Citations (Scopus)

A novel smoking cessation smartphone app integrated with a mobile carbon monoxide checker for smoking cessation treatment: Protocol for a randomized controlled trial

Nomura, A., Tateno, H., Masaki, K., Muto, T., Suzuki, S., Satake, K., Hida, E. & Fukunaga, K., 2019 Feb 1, In : Journal of medical Internet research. 21, 2, e12252.

Research output: Contribution to journalArticle

Open Access
Withholding Treatment
Smoking Cessation
Carbon Monoxide
Clinical Protocols
Randomized Controlled Trials

Antigen-driven selection of antibodies against SSA, SSB and the centromere 'complex', including a novel antigen, MIS12 complex, in human salivary glands

Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., Kato, S., Tsunoda, K., Arase, H. & Takeuchi, T., 2019 Jan 1, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Open Access
Centromere
Salivary Glands
Autoantibodies
Antigens
Anti-Idiotypic Antibodies
1 Citation (Scopus)

Antipsychotic treatment in the maintenance phase of schizophrenia: An updated systematic review of the guidelines and algorithms

Shimomura, Y., Kikuchi, Y., Suzuki, T., Uchida, H., Mimura, M. & Takeuchi, H., 2019 Jan 1, (Accepted/In press) In : Schizophrenia Research.

Research output: Contribution to journalArticle

Antipsychotic Agents
Schizophrenia
Maintenance
Guidelines
MEDLINE

Aortic stenosis with right-sided aortic arch treated with transfemoral aortic valve implantation

Yashima, F., Hayashida, K., Munakata, M., Arai, T., Shimizu, H. & Fukuda, K., 2019 Jan 25, In : Cardiovascular Intervention and Therapeutics. 34, 1, p. 70-71 2 p.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Thoracic Aorta
Aortic Valve
Transcatheter Aortic Valve Replacement

A phase 3 study of nivolumab in previously treated advanced gastric or gastroesophageal junction cancer (ATTRACTION-2): 2-year update data

Chen, L. T., Satoh, T., Ryu, M. H., Chao, Y., Kato, K., Chung, H. C., Chen, J. S., Muro, K., Kang, W. K., Yeh, K. H., Yoshikawa, T., Oh, S. C., Bai, L. Y., Tamura, T., Lee, K. W., Hamamoto, Y., Kim, J. G., Chin, K., Oh, D. Y., Minashi, K. & 5 others, Cho, J. Y., Tsuda, M., Sameshima, H., Kang, Y. K. & Boku, N., 2019 Jan 1, (Accepted/In press) In : Gastric Cancer.

Research output: Contribution to journalArticle

Open Access
Esophagogastric Junction
Stomach
Survival
Neoplasms
Placebos

A Phase II Study of Regorafenib With a Lower Starting Dose in Patients With Metastatic Colorectal Cancer: Exposure–Toxicity Analysis of Unbound Regorafenib and Its Active Metabolites (RESET Trial)

Suzuki, T., Sukawa, Y., Imamura, C. K., Masuishi, T., Satake, H., Kumekawa, Y., Funakoshi, S., Kotaka, M., Horie, Y., Kawai, S., Okuda, H., Terazawa, T., Kondoh, C., Kato, K., Yoshimura, K., Ishikawa, H., Hamamoto, Y., Boku, N., Takaishi, H. & Kanai, T., 2019 Jan 1, (Accepted/In press) In : Clinical Colorectal Cancer.

Research output: Contribution to journalArticle

Colorectal Neoplasms
regorafenib
1 Citation (Scopus)

A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients

Tani, T., Naoki, K., Yasuda, H., Arai, D., Ishioka, K., Ohgino, K., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T. & Soejima, K., 2019 Jan 1, (Accepted/In press) In : Cancer Chemotherapy and Pharmacology.

Research output: Contribution to journalArticle

Chemotherapy
Non-Small Cell Lung Carcinoma
Cells
Drug Therapy
Mutation
Open Access
Feasibility Studies
Cognitive Therapy
Japan
Anxiety
Students
11 Citations (Scopus)

APOE Alleles and Extreme Human Longevity

Sebastiani, P., Gurinovich, A., Nygaard, M., Sasaki, T., Sweigart, B., Bae, H., Andersen, S. L., Villa, F., Atzmon, G., Christensen, K., Arai, Y., Barzilai, N., Puca, A., Christiansen, L., Hirose, N. & Perls, T. T., 2019 Jan 1, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

Alleles
Genotype
Population
New England
Retirement
1 Citation (Scopus)

Applicability and limitations of a recently-proposed prognostic grading metric, initial brain metastasis velocity, for brain metastasis patients undergoing stereotactic radiosurgery

Yamamoto, M., Aiyama, H., Koiso, T., Watanabe, S., Kawabe, T., Sato, Y., Higuchi, Y., Kasuya, H. & Barfod, B. E., 2019 Jan 1, In : Journal of Neuro-Oncology.

Research output: Contribution to journalArticle

Radiosurgery
Neoplasm Metastasis
Brain
Neoplasms
Survival
6 Citations (Scopus)
Open Access
spinal cord injuries
Hepatocyte Growth Factor
Spinal Cord Injuries
roads
Rats
3 Citations (Scopus)

Application of high-performance magnetic nanobeads to biological sensing devices

Kabe, Y., Sakamoto, S., Hatakeyama, M., Yamaguchi, Y., Suematsu, M., Itonaga, M. & Handa, H., 2019 Jan 1, (Accepted/In press) In : Analytical and Bioanalytical Chemistry.

Research output: Contribution to journalArticle

Exosomes
Equipment and Supplies
Technology
Immunoassay
Drug Receptors
Open Access
Metabolomics
Epidemiologic Studies
Atherosclerosis
Cardiovascular Diseases
Metabolites

AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation

Hamaguchi, T., Tsutsui-Kimura, I., Mimura, M., Saito, T., Saido, T. C. & Tanaka, K., 2019 Oct 1, In : Neurochemistry International. 129, 104470.

Research output: Contribution to journalArticle

Amyloid Plaques
Motivation
Dopamine Plasma Membrane Transport Proteins
Apathy
Pathology

A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort

Ohwada, C., Sakaida, E., Igarashi, A., Kobayashi, T., Doki, N., Mori, T., Kato, J., Koda, Y., Kanamori, H., Tanaka, M., Tachibana, T., Fujisawa, S., Nakajima, Y., Numata, A., Toyosaki, M., Aoyama, Y., Onizuka, M., Hagihara, M., Koyama, S., Kanda, Y. & 9 others, Nakasone, H., Shimizu, H., Kato, S., Watanabe, R., Shono, K., Sakai, R., Saito, T., Nakaseko, C. & Okamoto, S., 2019 Jan 1, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

National Institutes of Health (U.S.)
Graft vs Host Disease
Observation
Survival
Incidence

Aquaporin4 (AQP4) in brain disorder

Yasui, M., 2019 Jan 1, In : Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 153, 5, p. 231-234 4 p.

Research output: Contribution to journalArticle

Brain Diseases
Water
Brain
Astrocytes
Neurodegenerative Diseases
1 Citation (Scopus)
Open Access
Aquaporin 4
Synaptic Transmission
Fatigue
Retina
Knockout Mice

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Teprenone in Patients with Alzheimer's Disease

Yokoyama, S., Yoshinaga, T., Matsuzaki, J. & Suzuki, H., 2019 Jan 1, In : Journal of Alzheimer's Disease. 71, 4, p. 1187-1199 13 p.

Research output: Contribution to journalArticle

geranylgeranylacetone
Alzheimer Disease
Placebos
Atrophy
Anti-Ulcer Agents
1 Citation (Scopus)

A randomized phase II study of nutritional and exercise treatment for elderly patients with advanced non-small cell lung or pancreatic cancer: The NEXTAC-TWO study protocol

Miura, S., Naito, T., Mitsunaga, S., Omae, K., Mori, K., Inano, T., Yamaguchi, T., Tatematsu, N., Okayama, T., Morikawa, A., Mouri, T., Tanaka, H., Kimura, M., Imai, H., Mizukami, T., Imoto, A., Kondoh, C., Shiotsu, S., Okuyama, H., Ueno, M. & 6 others, Takahashi, T., Tsuji, T., Aragane, H., Inui, A., Higashiguchi, T. & Takayama, K., 2019 May 31, In : BMC Cancer. 19, 1, 528.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Non-Small Cell Lung Carcinoma
Exercise
Neoplasms
Cachexia
Coronary Sinus
Atrial Heart Septal Defects
Tomography
3 Citations (Scopus)

Are We There Yet? How and When Specific Biotechnologies Will Improve Human Health

O'Day, E., Hosta-Rigau, L., Oyarzún, D. A., Okano, H., de Lorenzo, V., von Kameke, C., Alsafar, H., Cao, C., Chen, G. Q., Ji, W., Roberts, R. J., Ronaghi, M., Yeung, K., Zhang, F. & Lee, S. Y., 2019 Jan 1, In : Biotechnology Journal. 14, 1, 1800195.

Research output: Contribution to journalReview article

Open Access
glimepiride
Biotechnology
Hip
Hip Replacement Arthroplasties
Metformin

Armitage determines Piwi−piRISC processing from precursor formation and quality control to inter-organelle translocation

Yamashiro, H., Negishi, M., Kinoshita, T., Ishizu, H., Ohtani, H. & Siomi, M. C., 2019 Jan 1, (Accepted/In press) In : EMBO Reports. e48769.

Research output: Contribution to journalArticle

Quality Control
Organelles
Small Interfering RNA
Quality control
Processing

Artificial Intelligence in Psychiatry

Takamiya, A., Tazawa, Y., Kudo, K. & Kishimoto, T., 2019 Jan 1, In : Brain and nerve = Shinkei kenkyu no shinpo. 71, 1, p. 15-23 9 p.

Research output: Contribution to journalReview article

Artificial Intelligence
Mental Disorders
Neuroimaging
Psychiatry
Technology
7 Citations (Scopus)

Artificial intelligence to predict needs for urgent revascularization from 12-leads electrocardiography in emergency patients

Goto, S., Kimura, M., Katsumata, Y., Goto, S., Kamatani, T., Ichihara, G., Ko, S., Sasaki, J., Fukuda, K. & Sano, M., 2019 Jan 1, In : PLoS One. 14, 1, 0210103.

Research output: Contribution to journalArticle

Emergency rooms
artificial intelligence
Artificial Intelligence
electrocardiography
Electrocardiography
5 Citations (Scopus)

A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes

Asano, N., Matsuzaki, J., Ichikawa, M., Kawauchi, J., Takizawa, S., Aoki, Y., Sakamoto, H., Yoshida, A., Kobayashi, E., Tanzawa, Y., Nakayama, T. R., Morioka, H., Matsumoto, M., Nakamura, M., Kondo, T., Kato, K., Tsuchiya, N., Kawai, A. & Ochiya, T., 2019 Dec 1, In : Nature communications. 10, 1, 1299.

Research output: Contribution to journalArticle

Open Access
classifiers
MicroRNAs
Sarcoma
serums
Tumors
1 Citation (Scopus)

Asian society of gynecologic oncology international workshop 2018

Kong, T. W., Ryu, H. S., Kim, S. C., Enomoto, T., Li, J., Kim, K. H., Shim, S. H., Wang, P. H., Therasakvichya, S., Kobayashi, Y., Lee, M., Shi, T., Lee, S. W., Mikami, M., Nagase, S., Lim, M. C., Wang, J., Wilailak, S., Kim, S. W., Hong, S. H. & 21 others, Tan, D. S. P., Mandai, M., Chang, S. J., Huang, R. Y. J., Ushijima, K., Lee, J. Y., Chen, X., Ochiai, K., Lee, T. S., Yang, B., Kalam, F., Lv, Q., Ahmad, M. F., Yaznil, M. R., Modi, K. B., Manopunya, M., Jeong, D. H., Lertkhachonsuk, A. A., Chung, H. H., Watari, H. & Jeon, S., 2019 Mar 1, In : Journal of gynecologic oncology. 30, 2, e39.

Research output: Contribution to journalReview article

Education
Neoplasms
Endometrial Neoplasms
Korea
Uterine Cervical Neoplasms
Neoadjuvant Therapy
Esophagectomy
Propensity Score
Laparoscopy
Multicenter Studies
Cohort Studies
Carcinoma
Durapatite
Collagen
Bone and Bones
Dust
Mandibulofacial Dysostosis

Assessment of Bioabsorbable Hydroxyapatite for Secondary Bone Grafting in Unilateral Alveolar Clefts

Sakamoto, Y., Sakamoto, T., Ishii, T. & Kishi, K., 2019 Jan 1, (Accepted/In press) In : Cleft Palate-Craniofacial Journal.

Research output: Contribution to journalArticle

Bone Transplantation
Durapatite
Collagen
Bone and Bones
Maxillary Sinusitis

Assessment of lymphatic flow based on the sentinel node concept in early gastric adenocarcinoma that satisfies expanded endoscopic resection criteria

Takeuchi, M., Kawakubo, H., Shimada, A., Matsuda, S., Nakahara, T., Mayanagi, S., Irino, T., Fukuda, K., Nakamura, R., Wada, N., Takeuchi, H. & Kitagawa, Y., 2019 Jan 1, (Accepted/In press) In : Gastric Cancer.

Research output: Contribution to journalArticle

Stomach
Adenocarcinoma
Neoplasm Metastasis
Stomach Neoplasms
cyhalothrin
1 Citation (Scopus)

Assessment of Sex Differences in the Initial Symptom Burden, Applied Treatment Strategy, and Quality of Life in Japanese Patients With Atrial Fibrillation

Ikemura, N., Kosaka, S., Kimura, T., Ueda, I., Katsumata, Y., Nishiyama, T., Aizawa, Y., Tanimoto, K., Momiyama, Y., Akaishi, M., Mitamura, H., Fukuda, K., Spertus, J. A. & Takatsuki, S., 2019 Mar 1, In : JAMA network open. 2, 3, p. e191145

Research output: Contribution to journalArticle

Open Access
Sex Characteristics
Atrial Fibrillation
Quality of Life
Therapeutics
Brain Natriuretic Peptide

Assessment of the Mini-Balance Evaluation Systems Test, Timed Up and Go test, and body sway test between cancer survivors and healthy participants

Morishita, S., Hirabayashi, R., Tsubaki, A., Aoki, O., Fu, J. B., Onishi, H. & Tsuji, T., 2019 Oct 1, In : Clinical Biomechanics. 69, p. 28-33 6 p.

Research output: Contribution to journalArticle

Survivors
Healthy Volunteers
Hand Strength
Neoplasms
Muscle Strength

Association between acute fall in estimated glomerular filtration rate after treatment for primary aldosteronism and long-term decline in renal function

Kobayashi, H., Abe, M., Nakamura, Y., Takahashi, K., Fujita, M., Takeda, Y., Yoneda, T., Kurihara, I., Itoh, H., Tsuiki, M., Wada, N., Ichijo, T., Katabami, T., Ogawa, Y., Kawashima, J., Yoshimoto, T., Sone, M., Inagaki, N., Watanabe, M., Kamemura, K. & 6 others, Matsuda, Y., Izawa, S., Tanabe, M., Tanabe, A., Suzuki, T. & Naruse, M., 2019 Sep 1, In : Hypertension. 74, 3, p. 630-638 9 p.

Research output: Contribution to journalArticle

Hyperaldosteronism
Glomerular Filtration Rate
Kidney
Mineralocorticoid Receptor Antagonists
Therapeutics