School of Medicine

Research Output 1973 2020

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2019
3 Citations (Scopus)

Attitudes Toward Electroconvulsive Therapy among Involuntary and Voluntary Patients

Takamiya, A., Sawada, K., Mimura, M. & Kishimoto, T., 2019 Sep 1, In : Journal of ECT. 35, 3, p. 165-169 5 p.

Research output: Contribution to journalArticle

Electroconvulsive Therapy
Therapeutics
1 Citation (Scopus)
Open Access
Endometrial Hyperplasia
Aminolevulinic Acid
Endometrial Neoplasms
Biopsy
Hysteroscopy
1 Citation (Scopus)
Open Access
Adenomyoma
Hysteroscopy
Aminolevulinic Acid
Fertility Preservation
Recurrence
1 Citation (Scopus)

Autoimmunity and immunological tolerance in autoimmune bullous diseases

Takahashi, H., Iriki, H., Mukai, M., Kamata, A., Nomura, H., Yamagami, J. & Amagai, M., 2019 Jul 13, In : International immunology. 31, 7, p. 431-437 7 p.

Research output: Contribution to journalArticle

Open Access
Autoimmunity
Autoimmune Diseases
Pemphigus
Autoantigens
Desmogleins
1 Citation (Scopus)

Autologous hematopoietic cell transplantation for acute myeloid leukemia in adults: 25 years of experience in Japan

Yanada, M., Takami, A., Mizuno, S., Mori, J., Chou, T., Usuki, K., Uchiyama, H., Amano, I., Fujii, S., Miyamoto, T., Saito, T., Kamimura, T., Ichinohe, T., Fukuda, T., Okamoto, S., Atsuta, Y. & Yano, S., 2019 Jan 1, (Accepted/In press) In : International journal of hematology.

Research output: Contribution to journalArticle

Cell Transplantation
Acute Promyelocytic Leukemia
Acute Myeloid Leukemia
Japan
Transplantation

Automated Assessment of Existing Patient's Revised Cardiac Risk Index Using Algorithmic Software

Hofer, I. S., Cheng, D., Grogan, T., Fujimoto, Y., Yamada, T., Beck, L., Cannesson, M. & Mahajan, A., 2019 May 1, In : Anesthesia and analgesia. 128, 5, p. 909-916 8 p.

Research output: Contribution to journalArticle

Software
International Classification of Diseases
Hospital Mortality
ROC Curve
Cerebrovascular Disorders
12 Citations (Scopus)

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Saito, T., Kuma, A., Sugiura, Y., Ichimura, Y., Obata, M., Kitamura, H., Okuda, S., Lee, H. C., Ikeda, K., Kanegae, Y., Saito, I., Auwerx, J., Motohashi, H., Suematsu, M., Soga, T., Yokomizo, T., Waguri, S., Mizushima, N. & Komatsu, M., 2019 Dec 1, In : Nature communications. 10, 1, 1567.

Research output: Contribution to journalArticle

Open Access
Nuclear Receptor Co-Repressor 1
lipid metabolism
Peroxisome Proliferator-Activated Receptors
Autophagy
Lipid Metabolism
1 Citation (Scopus)

A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2

Tamura, R., Fujioka, M., Morimoto, Y., Ohara, K., Kosugi, K., Oishi, Y., Sato, M., Ueda, R., Fujiwara, H., Noji, S., Oishi, N., Ogawa, K., Kawakami, Y., Ohira, T., Yoshida, K. & Toda, M., 2019 Dec 1, In : Nature communications. 10, 1, 5758.

Research output: Contribution to journalArticle

Open Access
Neurofibromatosis 2
vaccines
Vascular Endothelial Growth Factor Receptor
Vaccines
Tumors

A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology

Yoshimatsu, S., Sone, T., Nakajima, M., Sato, T., Okochi, R., Ishikawa, M., Nakamura, M., Sasaki, E., Shiozawa, S. & Okano, H., 2019 Jan 1, In : PloS one. 14, 8, e0221164.

Research output: Contribution to journalArticle

Open Access
Gene Targeting
gene targeting
Callithrix
Genes
Stem cells

Balloon pulmonary angioplasty attenuates sleep apnea in patients with chronic thromboembolic pulmonary hypertension

Kohno, T., Fukuoka, R., Kawakami, T., Kataoka, M., Kimura, M., Sano, M. & Fukuda, K., 2019 Jan 1, In : Heart and Lung.

Research output: Contribution to journalArticle

Balloon Angioplasty
Sleep Apnea Syndromes
Pulmonary Hypertension
Lung
Apnea
1 Citation (Scopus)

Balloon pulmonary angioplasty for symptomatic chronic thromboembolic disease without pulmonary hypertension at rest

Inami, T., Kataoka, M., Kikuchi, H., Goda, A. & Satoh, T., 2019 Jan 1, In : International Journal of Cardiology.

Research output: Contribution to journalArticle

Balloon Angioplasty
Pulmonary Hypertension
Chronic Disease
Lung
Exercise

Basement membrane zone IgE deposition is associated with bullous pemphigoid disease severity and treatment results

Kamata, A., Kurihara, Y., Funakoshi, T., Takahashi, H., Kuroda, K., Hachiya, T., Amagai, M. & Yamagami, J., 2019 Jan 1, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Bullous Pemphigoid
Basement Membrane
Immunoglobulin E
Therapeutics
Blister

Being conscious of water intake positively associated with sufficient non-alcohol drink intake regardless of seasons and reasons in healthy Japanese; the KOBE study: A cross sectional study

Nishikawa, T., Miyamatsu, N., Higashiyama, A., Kubota, Y., Nishida, Y., Hirata, T., Sugiyama, D., Kuwabara, K., Kubo, S., Miyamoto, Y. & Okamura, T., 2019 Nov, In : International journal of environmental research and public health. 16, 21, 4151.

Research output: Contribution to journalArticle

Open Access
Drinking
Cross-Sectional Studies
Linear Models
Regression Analysis
Heat Stroke
42 Citations (Scopus)

Benchmarking Complications Associated with Esophagectomy

Low, D. E., Kuppusamy, M. K., Alderson, D., Cecconello, I., Chang, A. C., Darling, G., Davies, A., D'Journo, X. B., Gisbertz, S. S., Griffin, S. M., Hardwick, R., Hoelscher, A., Hofstetter, W., Jobe, B., Kitagawa, Y., Law, S., Mariette, C., Maynard, N., Morse, C. R., Nafteux, P. & 7 others, Pera, M., Pramesh, C. S., Puig, S., Reynolds, J. V., Schroeder, W., Smithers, M. & Wijnhoven, B. P. L., 2019 Feb 1, In : Annals of surgery. 269, 2, p. 291-298 8 p.

Research output: Contribution to journalArticle

Benchmarking
Esophagectomy
Chyle
Databases
Anastomotic Leak
2 Citations (Scopus)

Bi-allelic loss of function variants of TBX6 causes a spectrum of malformation of spine and rib including congenital scoliosis and spondylocostal dysostosis

Otomo, N., Takeda, K., Kawai, S., Kou, I., Guo, L., Osawa, M., Alev, C., Kawakami, N., Miyake, N., Matsumoto, N., Yasuhiko, Y., Kotani, T., Suzuki, T., Uno, K., Sudo, H., Inami, S., Taneichi, H., Shigematsu, H., Watanabe, K., Yonezawa, I. & 9 others, Sugawara, R., Taniguchi, Y., Minami, S., Kaneko, K., Nakamura, M., Matsumoto, M., Toguchida, J., Watanabe, K. & Ikegawa, S., 2019 Jan 1, In : Journal of medical genetics.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Scoliosis
Ribs
Spine
Haplotypes
1 Citation (Scopus)

Biological monitoring of o-toluidine in urine pretreated by an enzymatic deconjugation method

Eitaki, Y., Nakano, M., Kawai, T., Omae, K. & Takebayashi, T., 2019 Jan 1, In : Journal of occupational health.

Research output: Contribution to journalArticle

Open Access
2-toluidine
Environmental Monitoring
Urine
Monitoring
Metabolites
Open Access
Toes
Knee Joint
Leg
Knee
Exercise

Black pleural effusion caused by pancreatic pseudocyst rupture

Ishigaki, S., Kuwae, M., Ishii, M., Asakura, T., Ueda, S. & Betsuyaku, T., 2019 Feb 1, In : Clinical Case Reports. 7, 2, p. 385-386 2 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Pseudocyst
Pleural Effusion
Rupture
Alcoholic Pancreatitis
Chronic Pancreatitis

Blastemal predominant type Wilms tumor in Japan: Japan Children's Cancer Group

Koshinaga, T., Takimoto, T., Okita, H., Tanaka, Y., Inoue, E., Oue, T., Nozaki, M., Tsuchiya, K., Haruta, M., Kaneko, Y. & Fukuzawa, M., 2019 Apr 1, In : Pediatrics International. 61, 4, p. 351-357 7 p.

Research output: Contribution to journalArticle

Wilms Tumor
Japan
Neoplasms
Survival
Drug Therapy
3 Citations (Scopus)
Open Access
Mercury (metal)
Selenium
Manganese
Mercury
Cadmium
2 Citations (Scopus)

Body mass index as a tool for optimizing surgical care in coronary artery bypass grafting through understanding risks of specific complications

Nishioka, N., Ichihara, N., Bando, K., Motomura, N., Koyama, N., Miyata, H., Kohsaka, S., Takamoto, S. & Hashimoto, K., 2019 Jan 1, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

Coronary Artery Bypass
Body Mass Index
Morbidity
Odds Ratio
Confidence Intervals
1 Citation (Scopus)
Giant Cell Arteritis
Body Mass Index
Recurrence
1 Citation (Scopus)

Body Temperature, Heart Rate, and Short-Term Outcome of Cooled Infants

Tsuda, K., Iwata, S., Mukai, T., Shibasaki, J., Takeuchi, A., Ioroi, T., Sano, H., Yutaka, N., Takahashi, A., Takenouchi, T., Osaga, S., Tokuhisa, T., Takashima, S., Sobajima, H., Tamura, M., Hosono, S., Nabetani, M. & Iwata, O., 2019 Mar 1, In : Therapeutic Hypothermia and Temperature Management. 9, 1, p. 76-85 10 p.

Research output: Contribution to journalArticle

Open Access
Body Temperature
Heart Rate
Induced Hypothermia
Apgar Score
Brain Diseases

Bone marrow-derived mesenchymal stem cells enhance bone marrow regeneration in dental extraction sockets

Mashimo, T., Sato, Y., Akita, D., Toriumi, T., Namaki, S., Matsuzaki, Y., Yonehara, Y. & Honda, M., 2019 Jan 1, In : Journal of Oral Science. 61, 2, p. 284-293 10 p.

Research output: Contribution to journalArticle

Open Access
Tooth Socket
Tooth Extraction
Bone Regeneration
Mesenchymal Stromal Cells
Bone Marrow
Open Access
Single-Photon Emission-Computed Tomography
Neoplasm Metastasis
Bone and Bones
Tumor Burden
Prostatic Neoplasms

Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex

Shin, M., Kitazawa, A., Yoshinaga, S., Hayashi, K., Hirata, Y., Dehay, C., Kubo, K. & Nakajima, K., 2019 Jan 1, In : Journal of Comparative Neurology.

Research output: Contribution to journalArticle

Neocortex
Neurons
Interneurons
Primates
Occipital Lobe
1 Citation (Scopus)

Brain Changes Induced by Electroconvulsive Therapy Are Broadly Distributed

GEMRIC, 2019 Jan 1, (Accepted/In press) In : Biological Psychiatry.

Research output: Contribution to journalArticle

Open Access
Electroconvulsive Therapy
Brain
Major Depressive Disorder
Gray Matter
Research
1 Citation (Scopus)

Brain functional alterations observed 4-weekly in major depressive disorder following antidepressant treatment

Yamagata, B., Yamanaka, K., Takei, Y., Hotta, S., Hirano, J., Tabuchi, H. & Mimura, M., 2019 Jun 1, In : Journal of Affective Disorders. 252, p. 25-31 7 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Antidepressive Agents
Near-Infrared Spectroscopy
Brain
Sertraline

Brain metastasis-related microRNAs in patients with advanced breast cancer

Sato, J., Shimomura, A., Kawauchi, J., Matsuzaki, J., Yamamoto, Y., Takizawa, S., Sakamoto, H., Ohno, M., Narita, Y., Ochiya, T. & Tamura, K., 2019 Jan 1, In : PloS one. 14, 10, e0221538.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
microRNA
metastasis
breast neoplasms
Brain
1 Citation (Scopus)
Veins
Cavernous Sinus

Brief Report: Olfactory Adaptation in Children with Autism Spectrum Disorders

Kumazaki, H., Muramatsu, T., Miyao, M., Okada, K. I., Mimura, M. & Kikuchi, M., 2019 Jan 1, In : Journal of Autism and Developmental Disorders.

Research output: Contribution to journalArticle

Autism Spectrum Disorder
1 Citation (Scopus)

Broad Heterochromatic Domains Open in Gonocyte Development Prior to De Novo DNA Methylation

Yamanaka, S., Nishihara, H., Toh, H., Eijy Nagai, L. A., Hashimoto, K., Park, S. J., Shibuya, A., Suzuki, A. M., Tanaka, Y., Nakai, K., Carninci, P., Sasaki, H. & Siomi, H., 2019 Oct 7, In : Developmental Cell. 51, 1, p. 21-34.e5

Research output: Contribution to journalArticle

DNA Methylation
Genes
Genome
Methyltransferases
Chromatin
1 Citation (Scopus)

Calorie restriction enhances adult mouse lung stem cells function and reverses several ageing-induced changes

Hegab, A. E., Ozaki, M., Meligy, F. Y., Nishino, M., Kagawa, S., Ishii, M. & Betsuyaku, T., 2019 Jan 1, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Aging of materials
Lung
Epithelial Cells
3 Citations (Scopus)

Calpain Inhibition Restores Autophagy and Prevents Mitochondrial Fragmentation in a Human iPSC Model of Diabetic Endotheliopathy

Ong, S. B., Lee, W. H., Shao, N. Y., Ismail, N. I., Katwadi, K., Lim, M. M., Kwek, X. Y., Michel, N. A., Li, J., Newson, J., Tahmasebi, S., Rehman, J., Kodo, K., Jang, H. R. & Ong, S. G., 2019 Mar 5, In : Stem cell reports. 12, 3, p. 597-610 14 p.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Calpain
Endothelial cells
Autophagy
Stem cells
1 Citation (Scopus)

Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells

Tsugawa, H., Kato, C., Mori, H., Matsuzaki, J., Kameyama, K., Saya, H., Hatakeyama, M., Suematsu, M. & Suzuki, H., 2019 Jan 1, In : CMGH. 8, 3, p. 319-334 16 p.

Research output: Contribution to journalArticle

Open Access
Helicobacter
Neoplastic Stem Cells
Catenins
Protein Splicing
Histones
1 Citation (Scopus)

Can we predict amyloid deposition by objective cognition and regional cerebral blood flow in patients with subjective cognitive decline?

Funaki, K., Nakajima, S., Noda, Y., Wake, T., Ito, D., Yamagata, B., Yoshizaki, T., Kameyama, M., Nakahara, T., Murakami, K., Jinzaki, M., Mimura, M. & Tabuchi, H., 2019 Jan 1, (Accepted/In press) In : Psychogeriatrics.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Regional Blood Flow
Amyloid
Cognition
Single-Photon Emission-Computed Tomography
2 Citations (Scopus)

Cardiovascular health and cognitive functioning among centenarians: A comparison between the Tokyo and Georgia centenarian studies

Martin, P., Gondo, Y., Arai, Y., Ishioka, Y., Johnson, M. A., Miller, L. S., Woodard, J. L., Poon, L. W. & Hirose, N., 2019 Jan 1, In : International Psychogeriatrics.

Research output: Contribution to journalArticle

Tokyo
Health
C-Reactive Protein
Japan
Cardiovascular Diseases

Cardiovascular risk assessment chart by dietary factors in Japan: NIPPON DATA80

NIPPON DATA80 Research Group, 2019 Jan 1, In : Circulation Journal. 83, 6, p. 1254-1260 7 p.

Research output: Contribution to journalArticle

Open Access
Japan
Vegetables
Cardiovascular Diseases
Fruit
Salts

Cardiovascular Safety of Long-term Topical Application of a New Non-steroidal Anti-inflammatory Drug, S-flurbiprofen, in Patients with Osteoarthritis

Yataba, I., Kamada, Y., Matsushita, I., Matsumoto, H., Hoshino, Y. & Sato, A., 2019 Jan 1, In : Japanese Pharmacology and Therapeutics. 47, 3, p. 395-404 10 p.

Research output: Contribution to journalArticle

Flurbiprofen
Osteoarthritis
Anti-Inflammatory Agents
Safety
Pharmaceutical Preparations
Open Access
Carotid Intima-Media Thickness
Epidemiologic Studies
Computer aided design
Atherosclerosis
Japan
1 Citation (Scopus)
docetaxel
Castration
Androgens
Prostatic Neoplasms
Therapeutics

Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen

Fujita, K., Chakarov, S., Kobayashi, T., Sakamoto, K., Voisin, B., Duan, K., Nakagawa, T., Horiuchi, K., Amagai, M., Ginhoux, F. & Nagao, K., 2019 Jan 1, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 29, p. 14714-14723 10 p.

Research output: Contribution to journalArticle

Dendritic Cells
Spleen
Bone Marrow
Disintegrins
Metalloproteases
1 Citation (Scopus)

Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease

Kuzumaki, N., Suda, Y., Iwasawa, C., Narita, M., Sone, T., Watanabe, M., Maekawa, A., Matsumoto, T., Akamatsu, W., Igarashi, K., Tamura, H., Takeshima, H., Tawfik, V. L., Ushijima, T., Hattori, N., Okano, H. & Narita, M., 2019 Jun 1, In : Brain : a journal of neurology. 142, 6, p. 1675-1689 15 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Dopaminergic Neurons
Parkinson Disease
Induced Pluripotent Stem Cells
Clustered Regularly Interspaced Short Palindromic Repeats

Cerebral Infarction after Transcatheter Aortic Valve Implantation in Japan: Retrospective Analysis at a Single High-Volume Center

Iizuka, T., Oki, K., Hayashida, K., Minami, K., Izawa, Y., Takahashi, S., Shimizu, H., Fukuda, K. & Nakahara, J., 2019 Jan 1, (Accepted/In press) In : Journal of Stroke and Cerebrovascular Diseases. 104455.

Research output: Contribution to journalArticle

Cerebral Infarction
Japan
Catheters
Transcatheter Aortic Valve Replacement
Carotid Stenosis

Cerebrospinal pharmacokinetic and pharmacodynamic analysis of efficacy of meropenem in paediatric patients with bacterial meningitis

Ohata, Y., Tomita, Y., Sunakawa, K., Drusano, G. L. & Tanigawara, Y., 2019 Sep 1, In : International journal of antimicrobial agents. 54, 3, p. 292-300 9 p.

Research output: Contribution to journalArticle

meropenem
Bacterial Meningitides
Cerebrospinal Fluid
Pharmacokinetics
Pediatrics

Chagas disease: A report of 17 suspected cases in Japan, 2012-2017

Imai, K., Misawa, K., Osa, M., Tarumoto, N., Sakai, J., Mikita, K., Sayama, Y., Fujikura, Y., Kawana, A., Murakami, T., Maesaki, S., Miura, S. & Maeda, T., 2019 Jun 13, In : Tropical Medicine and Health. 47, 1, 38.

Research output: Contribution to journalArticle

Open Access
Chagas Disease
Japan
Trypanosoma cruzi
Parasitemia
Chagas Cardiomyopathy

Changeability of the rotatory direction in the stepping test caused by the anteverted or retroverted posture

Yasuda, T., Souma, K., Kunihiro, T. & Yasuda, K., 2019 Jan 1, In : Equilibrium Research. 78, 1, p. 39-42 4 p.

Research output: Contribution to journalArticle

Open Access
Posture
Arm
Leg
Weights and Measures
Gravitation

Changes in bone metabolic profile associated with pregnancy or lactation

Miyamoto, T., Miyakoshi, K., Sato, Y., Kasuga, Y., Ikenoue, S., Miyamoto, K., Nishiwaki, Y., Tanaka, M., Nakamura, M. & Matsumoto, M., 2019 Dec 1, In : Scientific reports. 9, 1, 6787.

Research output: Contribution to journalArticle

Open Access
Metabolome
Lactation
Breast Feeding
Mothers
Bone and Bones
3 Citations (Scopus)

Changes in Murine Subbasal Corneal Nerves After Scopolamine-Induced Dry Eye Stress Exposure

Simsek, C., Kojima, T., Nagata, T., Dogru, M. & Tsubota, K., 2019 Feb 1, In : Investigative ophthalmology & visual science. 60, 2, p. 615-623 9 p.

Research output: Contribution to journalArticle

Open Access
Scopolamine Hydrobromide
Tears
Dendritic Cells
Staining and Labeling
Fluorescein

Changes in sagittal alignment after surgical excision of thoracic spinal cord tumors in adults

Kobayashi, Y., Kawabata, S., Nishiyama, Y., Tsuji, O., Okada, E., Fujita, N., Yagi, M., Watanabe, K., Matsumoto, M., Nakamura, M. & Nagoshi, N., 2019 Jan 1, (Accepted/In press) In : Spinal Cord.

Research output: Contribution to journalArticle

Spinal Cord Neoplasms
Thorax
Spine
Kyphosis
Neoplasms