School of Medicine

Research Output 1973 2020

Filter
Article
2019

Early surgical intervention may facilitate recovery of cervical spinal cord injury in DISH

Tsuji, O., Suda, K., Takahata, M., Matsumoto-Harmon, S., Komatsu, M., Menjo, Y., Watanabe, K., Ishii, K., Nakamura, M., Matsumoto, M., Minami, A. & Iwasaki, N., 2019 Jan 1, In : Journal of Orthopaedic Surgery. 27, 1

Research output: Contribution to journalArticle

Open Access
Diffuse Idiopathic Skeletal Hyperostosis
Spinal Injuries
Spinal Cord Injuries
Paralysis
Wounds and Injuries

Editorial Comment

Kikuchi, E. & Mizuno, R., 2019 Jun 1, In : The Journal of urology. 201, 6, 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Anxiety Disorders
Benzodiazepines
Meta-Analysis
Safety
Antidepressive Agents

Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study

Ida, K., Miyamoto, T., Higuchi, S., Takeuchi, H., Yamada, S., Ono, M., Nishihara, H. & Shiozawa, T., 2019 Jul 1, In : Medical Oncology. 36, 7, 62.

Research output: Contribution to journalArticle

Neoplasms
Paraffin
Formaldehyde
Cost-Benefit Analysis
Ions
1 Citation (Scopus)

Effectiveness of inactivated influenza vaccine in children by vaccine dose, 2013–18

Shinjo(H), M., Sugaya, N., Furuichi, M., Araki, E., Maeda, N., Isshiki, K., Ohnishi, T., Nakamura, S., Yamada, G., Narabayashi, A., Nishida, M., Taguchi, N., Nakata, Y., Yoshida, M., Tsunematsu, K., Shibata, M., Munenaga, T., Hirano, Y., Ookawara, I., Sekiguchi, S. & 5 others, Kobayashi, Y., Yamaguchi, Y., Yoshida, N., Mitamura, K. & Takahashi, T., 2019 Jul 9, In : Vaccine. 37, 30, p. 4047-4054 8 p.

Research output: Contribution to journalArticle

Inactivated Vaccines
Influenza Vaccines
influenza
Human Influenza
Vaccines
Open Access
Exome
Transcriptome
Genes
RNA Splice Sites
Frameshift Mutation
Negative-Pressure Wound Therapy
Perforator Flap
Pressure Ulcer
Wounds and Injuries
Necrosis

Effect of axial length and age on the visual outcome of patients with idiopathic epiretinal membrane after pars plana vitrectomy

Minami, S., Shinoda, H., Shigeno, Y., Nagai, N., Kurihara, T., Watanabe, K., Sonobe, H., Takagi, H., Tsubota, K. & Ozawa, Y., 2019 Dec 1, In : Scientific reports. 9, 1, 19056.

Research output: Contribution to journalArticle

Open Access
Epiretinal Membrane
Temazepam
Vitrectomy
Visual Acuity
Confidence Intervals

Effect of body mass index on surgical times of lumbar laminoplasty and lower limb arthroplasties

Harato, K., Yagi, M., Fujita, N., Kobayashi, S., Ohya, A., Kaneda, K., Iwama, Y., Nakamura, M. & Matsumoto, M., 2019 Sep 6, In : BMC Musculoskeletal Disorders. 20, 1, 416.

Research output: Contribution to journalArticle

Open Access
Operative Time
Knee Osteoarthritis
Arthroplasty
Lower Extremity
Body Mass Index

Effect of eyelid hygiene detergent on obstructive meibomian gland dysfunction

Tanabe, H., Kaido, M., Kawashima, M., Ishida, R., Ayaki, M. & Tsubota, K., 2019 Jan 1, In : Journal of Oleo Science. 68, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

Detergents
Water
Fluorescein
1 Citation (Scopus)

Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts

Hegab, A. E., Ozaki, M., Kameyama, N., Gao, J., Kagawa, S., Yasuda, H., Soejima, K., Yin, Y., Guzy, R. D., Nakamura, Y., Ornitz, D. M. & Betsuyaku, T., 2019 Jan 1, In : Journal of Pathology.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Fibroblast Growth Factors
Neoplasms
Lung
Cancer-Associated Fibroblasts

Effect of First-line S-1 Plus Oxaliplatin With or Without Ramucirumab Followed by Paclitaxel Plus Ramucirumab on Advanced Gastric Cancer in East Asia: The Phase 2 RAINSTORM Randomized Clinical Trial

Yoshikawa, T., Muro, K., Shitara, K., Oh, D. Y., Kang, Y. K., Chung, H. C., Kudo, T., Chin, K., Kadowaki, S., Hamamoto, Y., Hironaka, S., Yoshida, K., Yen, C. J., Omuro, Y., Bai, L. Y., Maeda, K., Ozeki, A., Yoshikawa, R. & Kitagawa, Y., 2019 Aug 2, In : JAMA network open. 2, 8, p. e198243

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Far East
Paclitaxel
Stomach Neoplasms
Randomized Controlled Trials

Effect of midazolam, medetomidine, and butorphanol tartrate combination anesthetic on electroretinograms of mice

Miwa, Y., Tsubota, K. & Kurihara, T., 2019 Jan 1, In : Molecular vision. 25, p. 645-653 9 p.

Research output: Contribution to journalArticle

Medetomidine
Butorphanol
Midazolam
Pentobarbital
Xylazine
1 Citation (Scopus)

Effect of natural full weight-bearing during standing on the rotation of the first metatarsal bone

Ota, T., Nagura, T., Yamada, Y., Yamada, M., Yokoyama, Y., Ogihara, N., Matsumoto, M., Nakamura, M. & Jinzaki, M., 2019 Jan 1, In : Clinical Anatomy.

Research output: Contribution to journalArticle

Metatarsal Bones
Weight-Bearing
Pronation
Foot
Leg

Effect of refrigeration of blood samples in lithium-heparin tubes on QuantiFERON TB Gold Plus test result

Uwamino, Y., Sakai, A., Nishimura, T., Noguchi, M., Uno, S., Fujiwara, H., Mori, M., Wakui, M., Murata, M. & Hasegawa, N., 2019 Jan 1, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Refrigeration
Lithium
Gold
Heparin
Product Labeling
2 Citations (Scopus)

Effect of Taxane Plus Platinum Regimens vs Doxorubicin Plus Cisplatin as Adjuvant Chemotherapy for Endometrial Cancer at a High Risk of Progression: A Randomized Clinical Trial

Nomura, H., Aoki, D., Michimae, H., Mizuno, M., Nakai, H., Arai, M., Sasagawa, M., Ushijima, K., Sugiyama, T., Saito, M., Tokunaga, H., Matoda, M., Nakanishi, T., Watanabe, Y., Takahashi, F., Saito, T. & Yaegashi, N., 2019 Jan 1, In : JAMA Oncology.

Research output: Contribution to journalArticle

docetaxel
Adjuvant Chemotherapy
Endometrial Neoplasms
Platinum
Doxorubicin

Effects of hyperoxia on the refraction in murine neonatal and adult models

Mori, K., Kurihara, T., Jiang, X., Ikeda, S. I., Ishida, A., Torii, H. & Tsubota, K., 2019 Dec 1, In : International journal of molecular sciences. 20, 23, 6014.

Research output: Contribution to journalArticle

Open Access
hyperoxia
Hyperoxia
Refraction
refraction
Oxygen
1 Citation (Scopus)

Effects of leg motor imagery combined with electrical stimulation on plasticity of corticospinal excitability and spinal reciprocal inhibition

Takahashi, Y., Kawakami, M., Yamaguchi, T., Idogawa, Y., Tanabe, S., Kondo, K. & Liu, M., 2019 Jan 1, In : Frontiers in Neuroscience. 13, FEB, 149.

Research output: Contribution to journalArticle

Open Access
Imagery (Psychotherapy)
Electric Stimulation
Leg
Lower Extremity
Muscles

Effects of polypharmacy and anticholinergic/sedative drugs on the physical/cognitive/ mental related outcomes of community-dwelling elderly people: The kawasaki wellbeing project

Tanaka, A., Arai, Y., Hirata, T., Abe, Y., Oguma, Y. & Urushihara, H., 2019 Jan 1, In : Japanese Journal of Geriatrics. 56, 4, p. 504-515 12 p.

Research output: Contribution to journalArticle

Open Access
Independent Living
Polypharmacy
Cholinergic Antagonists
Hypnotics and Sedatives
Pharmaceutical Preparations

Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency

Sasaki, G., Ishii, T., Hori, N., Amano, N., Homma, K., Sato, S. & Hasegawa, T., 2019 Jan 1, In : Endocrine journal. 66, 9, p. 837-842 6 p.

Research output: Contribution to journalArticle

Open Access
Dihydrotestosterone
Oxidoreductases
Prostate
Therapeutics
Steroids
Postoperative Nausea and Vomiting
Scoliosis
Dexamethasone
Randomized Controlled Trials
Placebos

Effects of sulfur dioxide on fractional exhaled nitric oxide concentration in the child residents of Miyakejima Island

Iwasawa, S., Tsuboi, T., Nakano, M., Hirata, A., Yoshioka, N., Suzuki, S., Tanaka, S. & Omae, K., 2019 Jun 1, In : Asian Journal of Atmospheric Environment. 13, 2, p. 145-149 5 p.

Research output: Contribution to journalArticle

nitric oxide
sulfur dioxide
student
volcanic gas
dose-response relationship

Effects of vedolizumab in Japanese patients with Crohn’s disease: a prospective, multicenter, randomized, placebo-controlled Phase 3 trial with exploratory analyses

Watanabe, K., Motoya, S., Ogata, H., Kanai, T., Matsui, T., Suzuki, Y., Shikamura, M., Sugiura, K., Oda, K., Hori, T., Araki, T., Watanabe, M. & Hibi, T., 2019 Jan 1, (Accepted/In press) In : Journal of gastroenterology.

Research output: Contribution to journalArticle

Open Access
Crohn Disease
Placebos
Maintenance
Odds Ratio
Confidence Intervals
3 Citations (Scopus)

Efficacy and safety of 0.6% sodium alginate solution in endoscopic submucosal dissection for esophageal and gastric neoplastic lesion: A randomized controlled study

Uemura, N., Oda, I., Saito, Y., Ono, H., Fujisaki, J., Matsuhashi, N., Ohata, K., Yahagi, N., Yada, T., Satoh, M., Tajiri, H., Inomata, M. & Kitano, S., 2019 Jan 1, In : Digestive Endoscopy.

Research output: Contribution to journalArticle

Open Access
Hyaluronic Acid
Stomach
Safety
Injections
Gastric Mucosa
2 Citations (Scopus)

Efficacy and safety of autologous stem cell transplantation in patients aged ≥ 65 years with multiple myeloma in the era of novel agents

Mizuno, S., Kawamura, K., Hanamura, I., Sunami, K., Mori, T., Nakamura, F., Iida, S., Nakazawa, H., Makita, M., Kako, S., Sawa, M., Ueda, Y., Takahashi, H., Kanda, Y., Ichinohe, T., Atsuta, Y., Takamatsu, H. & Takami, A., 2019 Jan 1, In : Bone Marrow Transplantation.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Multiple Myeloma
Hematopoietic Stem Cell Transplantation
Safety
Confidence Intervals
Open Access
Albuminuria
Type 2 Diabetes Mellitus
Blood Pressure
Safety
Glomerular Filtration Rate
3 Citations (Scopus)
Open Access
Double-Blind Method
Placebos
Blood Pressure
Safety
Therapeutics

Efficacy and safety of JAK inhibitors; Including therapeutic positioning

Naganuma, M., 2019 Jan 1, In : Journal of Japanese Society of Gastroenterology. 116, 3, p. 200-207 8 p.

Research output: Contribution to journalArticle

Safety
Therapeutics
Open Access
Mitomycin
Pancreatic Neoplasms
Fluorouracil
Cisplatin
Radiotherapy
2 Citations (Scopus)

Efficacy and safety of sirolimus treatment for intractable lymphatic anomalies: A study protocol for an open-label, single-arm, multicenter, prospective study (SILA)

Ozeki, M., Asada, R., Saito, A. M., Hashimoto, H., Fujimura, T., Kuroda, T., Ueno, S., Watanabe, S., Nosaka, S., Miyasaka, M., Umezawa, A., Matsuoka, K., Maekawa, T., Yamada, Y., Fujino, A., Hirakawa, S., Furukawa, T., Tajiri, T., Kinoshita, Y., Souzaki, R. & 1 others, Fukao, T., 2019 Jun 1, In : Regenerative Therapy. 10, p. 84-91 8 p.

Research output: Contribution to journalArticle

Sirolimus
Multicenter Studies
Labels
Prospective Studies
Safety
Open Access
compound A 12
Type 2 Diabetes Mellitus
Safety
Hypoglycemia
Hypoglycemic Agents
2 Citations (Scopus)
Leukemia, Myeloid, Chronic Phase
Protein-Tyrosine Kinases
Registries
Safety
Disease-Free Survival
6 Citations (Scopus)

Efficacy of afatinib or osimertinib plus cetuximab combination therapy for non-small-cell lung cancer with EGFR exon 20 insertion mutations

Hasegawa, H., Yasuda, H., Hamamoto, J., Masuzawa, K., Tani, T., Nukaga, S., Hirano, T., Kobayashi, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Lung Cancer. 127, p. 146-152 7 p.

Research output: Contribution to journalArticle

Insertional Mutagenesis
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Exons
Therapeutics

Efficacy of enteral nutrition by double elementary diet tube after pylorus-preserving pancreatoduodenectomy

Sano, T., Chiba, N., Gunji, T., Ozawa, Y., Hikita, K., Okihara, M., Tomita, K., Oshima, G., Takano, K., Abe, Y., Shimazu, M. & Kawachi, S., 2019 Apr 1, In : American Surgeon. 85, 4, p. 359-364 6 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Pylorus
Enteral Nutrition
Diet
Pancreatic Fistula

Efficacy of New Polylactic Acid Nonwoven Fabric as a Hemostatic Agent in a Rat Liver Resection Model

Wakabayashi, T., Yagi, H., Tajima, K., Kuroda, K., Shinoda, M., Kitago, M., Abe, Y., Oshima, G., Hirukawa, K., Itano, O. & Kitagawa, Y., 2019 Jan 1, In : Surgical Innovation.

Research output: Contribution to journalArticle

Hemostatics
Liver
Minimally Invasive Surgical Procedures
von Willebrand Factor
Hemostasis
3 Citations (Scopus)

Efficacy of Plate Expression of Meibum on Tear Function and Ocular Surface Findings in Meibomian Gland Disease

Aketa, N., Shinzawa, M., Kawashima, M., Dogru, M., Okamoto, S., Tsubota, K. & Shimazaki, J., 2019 Jan 1, In : Eye & contact lens. 45, 1, p. 19-22 4 p.

Research output: Contribution to journalArticle

Meibomian Glands
Tears
Therapeutics
Quality of Life
Staining and Labeling

Efficacy of seasonal allergic rhinitis using an 810 nm diode laser system

Sasaki, K., Ohshiro, T., Sakio, R., Toriumi, M., Hatano, A., Fukazawa, E., Kono, T., Yoshihama, K., Ogawa, K. & Ohshiro, T., 2019 Jan 1, In : Laser Therapy. 28, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Semiconductor Lasers
Seasonal Allergic Rhinitis
Semiconductor lasers
Antibodies
Immunoglobulin E
1 Citation (Scopus)

Efficacy of therapeutic intervention for patients with an ulcerative colitis mayo endoscopic score of 1

Fukuda, T., Naganuma, M., Sugimoto, S., Ono, K., Nanki, K., Mizuno, S., Hukuhara, K., Mutaguchi, M., Nakazato, Y., Takabayashi, K., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2019 Mar 14, In : Inflammatory bowel diseases. 25, 4, p. 782-788 7 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Recurrence
Colonoscopy
Therapeutics
Blood Vessels
1 Citation (Scopus)

Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing

Kumita, W., Sato, K., Suzuki, Y., Kurotaki, Y., Harada, T., Zhou, Y., Kishi, N., Sato, K., Aiba, A., Sakakibara, Y., Feng, G., Okano, H. & Sasaki, E., 2019 Dec 1, In : Scientific reports. 9, 1, 12719.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Callithrix
Embryonic Structures
Gene Knockout Techniques
Primates
Open Access
Electroconvulsive Therapy
Depressive Disorder
Electroencephalography
Gyrus Cinguli
Depression
13 Citations (Scopus)

Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis

Ladinsky, M. S., Araujo, L. P., Zhang, X., Veltri, J., Galan-Diez, M., Soualhi, S., Lee, C., Irie, K., Pinker, E. Y., Narushima, S., Bandyopadhyay, S., Nagayama, M., Elhenawy, W., Coombes, B. K., Ferraris, R. P., Honda, K., Iliev, I. D., Gao, N., Bjorkman, P. J. & Ivanov, I. I., 2019 Jan 1, In : Science. 363, 6431, eaat4042.

Research output: Contribution to journalArticle

Endocytosis
Homeostasis
Epithelial Cells
Bacteria
T-Lymphocytes
Empty Sella Syndrome
Prolactinoma
Cartilage
Bone and Bones
Optic Chiasm
2 Citations (Scopus)

Endoscopic Endonasal Approach Combined with a Simultaneous Transcranial Approach for Giant Pituitary Tumors

Kuga, D., Toda, M., Ozawa, H., Ogawa, K. & Yoshida, K., 2019 Jan 1, In : World Neurosurgery. 121, p. 173-179 7 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Neoplasms
Hypothyroidism
Adenoma
Adrenocorticotropic Hormone
1 Citation (Scopus)

Endoscopic Endonasal Removal of Large Calcified Pituitary Adenoma: Case Report and Review of the Literature

Murase, M., Toda, M., Ohara, K., Ishihara, E. & Yoshida, K., 2019 Mar 1, In : World Neurosurgery. 123, p. 239-243 5 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Magnetic Resonance Imaging
Amenorrhea
Gadolinium
Neoplasms
3 Citations (Scopus)

Endoscopic surgery in Japan: The 13th national survey (2014-2015) by the Japan Society for Endoscopic Surgery

Shiroshita, H., Inomata, M., Bandoh, T., Uchida, H., Akira, S., Hashizume, M., Yamaguchi, S., Eguchi, S., Wada, N., Takiguchi, S., Ieiri, S., Endo, S., Iwazaki, M., Tamaki, Y., Tabata, M., Kanayama, H., Mimata, H., Hasegawa, T., Onishi, K., Yanaga, K. & 6 others, Morikawa, T., Terachi, T., Matsumoto, S., Yamashita, Y., Kitano, S. & Watanabe, M., 2019 Jan 1, In : Asian journal of endoscopic surgery. 12, 1, p. 7-18 12 p.

Research output: Contribution to journalArticle

Open Access
Japan
Surveys and Questionnaires
Social Distance
Laparoscopic Cholecystectomy
Operative Surgical Procedures
2 Citations (Scopus)

Endothelial-mesenchymal transition drives expression of CD44 variant and xCT in pulmonary hypertension

Isobe, S., Kataoka, M., Endo, J., Moriyama, H., Okazaki, S., Tsuchihashi, K., Katsumata, Y., Yamamoto, T., Shirakawa, K., Yoshida, N., Shimoda, M., Chiba, T., Masuko, T., Hakamata, Y., Kobayashi, E., Saya, H., Fukuda, K. & Sano, M., 2019 Jan 1, In : American journal of respiratory cell and molecular biology. 61, 3, p. 367-379 13 p.

Research output: Contribution to journalArticle

Sulfasalazine
Pulmonary Hypertension
Glutathione
Antioxidants
Chemotherapy

Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis

Zahra, F. T., Sajib, M. S., Ichiyama, Y., Akwii, R. G., Tullar, P. E., Cobos, C., Minchew, S. A., Doçi, C. L., Zheng, Y., Kubota, Y., Gutkind, J. S. & Mikelis, C. M., 2019 Dec 1, In : Scientific reports. 9, 1, 11666.

Research output: Contribution to journalArticle

Open Access
GTP Phosphohydrolases
Embryonic Development
rho GTP-Binding Proteins
Cell Movement
Physiologic Neovascularization

Endothelial specific deletion of FOXO1 alters pericyte coverage in the developing retina

Niimi, K., Adachi, Y., Ishikawa, H., Yamaguchi, W., Kubota, Y., Inagaki, S. & Furuyama, T., 2019 Dec 3, In : Biochemical and Biophysical Research Communications. 520, 2, p. 304-310 7 p.

Research output: Contribution to journalArticle

Pericytes
Retina
Endothelium
Thrombospondin 1
Endothelial cells

Enriched environment alleviates stress-induced dry-eye through the BDNF axis

Sano, K., Kawashima, M., Imada, T., Suzuki, T., Nakamura, S., Mimura, M., Tanaka, K. & Tsubota, K., 2019 Dec 1, In : Scientific reports. 9, 1, 3422.

Research output: Contribution to journalArticle

Open Access
Brain-Derived Neurotrophic Factor
Tears
Eye Diseases
Gene Knockdown Techniques
Mental Disorders

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

Kobayashi, H., Morikawa, T., Okinaga, A., Hamano, F., Hashidate-Yoshida, T., Watanuki, S., Hishikawa, D., Shindou, H., Arai, F., Kabe, Y., Suematsu, M., Shimizu, T. & Takubo, K., 2019 Jul 2, In : Cell Reports. 28, 1, p. 145-158.e9

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cells
Stem cells
Maintenance
Fatty Acids
Cell culture