Departments of Basic Medical Sciences

Research Output 1978 2020

2019
1 Citation (Scopus)

Time-related changes in relationships between the keys score, dietary lipids, and serum total cholesterol in Japan ― NIPPON DATA80/90/2010 ―

NIPPON DATA80/90 NIPPON DATA2010 Research Groups, 2019 Jan 1, In : Circulation Journal. 83, 1, p. 147-155 9 p.

Research output: Contribution to journalArticle

Japan
Cholesterol
Lipids
Dietary Cholesterol
Serum

Timing and shaping mechanisms of neural development

Kageyama, R. & Nakajima, K., 2019 Jan 1, In : Neuroscience Research. 138, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Tissue regulatory T cells and neural repair

Ito, M., Komai, K., Nakamura, T., Srirat, T. & Yoshimura, A., 2019 May 21, In : International immunology. 31, 6, p. 361-369 9 p.

Research output: Contribution to journalArticle

Open Access
Regulatory T-Lymphocytes
Brain
Serotonin
Inflammation
Serotonin Receptors
6 Citations (Scopus)

Treatment Optimization for Hepatocellular Carcinoma in Elderly Patients in a Japanese Nationwide Cohort

Liver Cancer Study Group of Japan, 2019 Jul 1, In : Annals of surgery. 270, 1, p. 121-130 10 p.

Research output: Contribution to journalArticle

Open Access
Hepatocellular Carcinoma
Confidence Intervals
Survival
Propensity Score
Recurrence

Update of occupational lung disease

Japan Society for Occupational Health Occupational Lung Disease Study Group, 2019 Jan 1, In : Journal of Occupational Health. 61, 1, p. 10-18 9 p.

Research output: Contribution to journalReview article

Occupational diseases
Pulmonary diseases
Occupational Diseases
Lung Diseases
Occupational Health

Use of the National Clinical Database to evaluate the association between preoperative liver function and postoperative complications among patients undergoing hepatectomy

Kubota, K., Aoki, T., Kumamaru, H., Shiraki, T., Miyata, H., Seto, Y., Kakeji, Y. & Yamamoto, M., 2019 Jan 1, In : Journal of Hepato-Biliary-Pancreatic Sciences. 26, 8, p. 331-340 10 p.

Research output: Contribution to journalArticle

Hepatectomy
Indocyanine Green
Databases
Liver
Surgical Wound Infection

Validation of the Accuracy of Self-Reported ABO Blood Types in the Japan Nurses’ Health Study

Alkebsi, L., Ohnishi, H., Nakajima-Shimada, J., Onizuka, Y., Ideno, Y., Sato, Y. & Hayashi, K., 2019 Mar 26, In : Asian Pacific journal of cancer prevention : APJCP. 20, 3, p. 789-793 5 p.

Research output: Contribution to journalArticle

Open Access
Japan
Nurses
Health
Blood Group Antigens
Cohort Studies
5 Citations (Scopus)

Validity of a Recently Proposed Prognostic Grading Index, Brain Metastasis Velocity, for Patients With Brain Metastasis Undergoing Multiple Radiosurgical Procedures

Yamamoto, M., Aiyama, H., Koiso, T., Watanabe, S., Kawabe, T., Sato, Y., Higuchi, Y., Kasuya, H. & Barfod, B. E., 2019 Mar 1, In : International Journal of Radiation Oncology Biology Physics. 103, 3, p. 631-637 7 p.

Research output: Contribution to journalArticle

Radiosurgery
metastasis
brain
confidence
Neoplasm Metastasis
2 Citations (Scopus)
Aortic Valve Insufficiency
Japan
Databases
Transplants
Mortality

Variation in process quality measures of diabetes care by region and institution in Japan during 2015–2016: An observational study of nationwide claims data

Sugiyama, T., Imai, K., Ihana-Sugiyama, N., Tanaka, H., Yanagisawa-Sugita, A., Sasako, T., Higashi, T., Okamura, T., Yamauchi, T., Ueki, K., Ohsugi, M. & Kadowaki, T., 2019 Jan 1, In : Diabetes Research and Clinical Practice. 107750.

Research output: Contribution to journalArticle

Open Access
Process Assessment (Health Care)
Certification
Observational Studies
Japan
Outpatients
1 Citation (Scopus)
Vegetable Proteins
Chemical vapor deposition
Mortality
Hazards
Population
1 Citation (Scopus)

Visualization of spatiotemporal dynamics of human glioma stem cell invasion

Tamura, R., Miyoshi, H., Sampetrean, O., Shinozaki, M., Morimoto, Y., Iwasawa, C., Fukaya, R., Mine, Y., Masuda, H., Maruyama, T., Narita, M., Saya, H., Yoshida, K., Okano, H. & Toda, M., 2019 May 6, In : Molecular brain. 12, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Glioma
Stem Cells
Glioblastoma
Axons
Time-Lapse Imaging

Which patients are candidates for minimally invasive mitral valve surgery? Establishment of risk calculators using national clinical database

Japan Cardiovascular Surgery Database Organization, 2019 Jan 1, In : Circulation Journal. 83, 8, p. 1674-1681 8 p.

Research output: Contribution to journalArticle

Open Access
Mitral Valve
Databases
Mortality
ROC Curve
Patient Selection

αGlcNAc and its catalyst α4GnT are diagnostic and prognostic markers in uterine cervical tumor, gastric type

Ida, K., Yamanoi, K., Asaka, S., Takeuchi, H., Miyamoto, T., Shiozawa, T. & Nakayama, J., 2019 Sep 10, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Stomach
Hyperplasia
Papillomaviridae
Neoplasms
Virus Diseases
2018
8 Citations (Scopus)

Accuracy of non-invasive scoring systems for diagnosing non-alcoholic steatohepatitis-related fibrosis: Multicenter validation study

Itoh, Y., Seko, Y., Shima, T., Nakajima, T., Mizuno, K., Kawamura, Y., Akuta, N., Ito, K., Kawanaka, M., Hiramatsu, A., Sakamoto, M., Harada, K., Goto, Y., Nakayama, T., Kumada, H. & Okanoue, T., 2018 Jan 1, (Accepted/In press) In : Hepatology Research.

Research output: Contribution to journalArticle

Validation Studies
Fatty Liver
Multicenter Studies
Fibrosis
Liver Cirrhosis

A combination of routine laboratory findings and vital signs can predict survival of advanced cancer patients without physician evaluation: a fractional polynomial model

Hamano, J., Takeuchi, A., Yamaguchi, T., Baba, M., Imai, K., Ikenaga, M., Matsumoto, Y., Sekine, R., Yamaguchi, T., Hirohashi, T., Tajima, T., Tatara, R., Watanabe, H., Otani, H., Nagaoka, H., Mori, M., Tei, Y., Hiramoto, S. & Morita, T., 2018 Dec 1, In : European Journal of Cancer. 105, p. 50-60 11 p.

Research output: Contribution to journalArticle

Vital Signs
Statistical Models
Physicians
Survival
Neoplasms
11 Citations (Scopus)

Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer

Watanabe, M., Narita, M., Hamada, Y., Yamashita, A., Tamura, H., Ikegami, D., Kondo, T., Shinzato, T., Shimizu, T., Fukuchi, Y., Muto, A., Okano, H., Yamanaka, A., Tawfik, V. L., Kuzumaki, N., Navratilova, E., Porreca, F. & Narita, M., 2018 Jan 1, In : Molecular Pain. 14

Research output: Contribution to journalArticle

Bone Neoplasms
Ventral Tegmental Area
Dopaminergic Neurons
Hyperalgesia
Nucleus Accumbens
Osteosarcoma
Pediatrics
Neoplasms
Inbred C3H Mouse
Therapeutics
7 Citations (Scopus)

ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death

Ueno, M., Shiomi, T., Mochizuki, S., Chijiiwa, M., Shimoda, M., Kanai, Y., Kataoka, F., Hirasawa, A., Susumu, N., Aoki, D. & Okada, Y., 2018 Feb 1, In : Cancer Science. 109, 2, p. 471-482 12 p.

Research output: Contribution to journalArticle

Cisplatin
Cell Death
Carcinoma
Disintegrins
Metalloproteases
Intestinal Perforation
Intestinal Obstruction
Peritoneal Dialysis
Adhesives
Peritonitis
1 Citation (Scopus)

A grading system that predicts the risk of dialysis induction in IgA nephropathy patients based on the combination of the clinical and histological severity

for The Special IgA Nephropathy Study Group, 2018 Jan 1, (Accepted/In press) In : Clinical and Experimental Nephrology.

Research output: Contribution to journalArticle

Immunoglobulin A
Dialysis
IGA Glomerulonephritis
Chronic Kidney Failure
Glomerular Filtration Rate
4 Citations (Scopus)

Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions

Sugiura, Y., Takeo, E., Shimma, S., Yokota, M., Higashi, T., Seki, T., Mizuno, Y., Oya, M., Kosaka, T., Omura, M., Nishikawa, T., Suematsu, M. & Nishimoto, K., 2018 Dec 1, In : Hypertension (Dallas, Tex. : 1979). 72, 6, p. 1345-1354 10 p.

Research output: Contribution to journalArticle

Aldosterone
Hyperaldosteronism
Adenoma
Cytochrome P-450 CYP11B2
18-oxocortisol
1 Citation (Scopus)

Alteration of global protein SUMOylation in neurons and astrocytes in response to Alzheimer's disease-associated insults

Maruyama, T., Wada, H., Abe, Y. & Niikura, T., 2018 Jun 2, In : Biochemical and Biophysical Research Communications. 500, 2, p. 470-475 6 p.

Research output: Contribution to journalArticle

Sumoylation
Astrocytes
Neurons
Alzheimer Disease
Ubiquitin
4 Citations (Scopus)

A method for determination of aldosterone in adrenal tributary venous serum by derivatization using Girard P reagent isotopologues followed by LC/ESI-MS/MS

Higashi, T., Akaishi, M., Yokota, M., Suzuki, T., Ogawa, S., Sugiura, Y., Nishikawa, T., Nishimoto, K. & Suematsu, M., 2018 Aug 15, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1092, p. 106-113 8 p.

Research output: Contribution to journalArticle

Aldosterone
Serum
Sampling
Hyperaldosteronism
Assays
Hypoglossal Nerve
Arteriovenous Fistula
Hypoglossal Nerve Diseases
Veins
Digital Subtraction Angiography
3 Citations (Scopus)

Anatomic basis for flap thinning

Park, S. O., Chang, H. & Imanishi, N., 2018 Jul 1, In : Archives of Plastic Surgery. 45, 4, p. 298-303 6 p.

Research output: Contribution to journalArticle

Perforator Flap
Epigastric Arteries
Thigh
Blood Vessels
Anatomy
8 Citations (Scopus)

An epidemic of bladder cancer: Ten cases of bladder cancer in male Japanese workers exposed to ortho-toluidine

Nakano, M., Omae, K., Takebayashi, T., Tanaka, S. & Koda, S., 2018 Jan 1, In : Journal of Occupational Health. 60, 4, p. 307-311 5 p.

Research output: Contribution to journalArticle

2-toluidine
Urinary Bladder Neoplasms
Amines
Coloring Agents
International Agencies
7 Citations (Scopus)

Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction

Lee, S. J., Lee, C. K., Kang, S., Park, I., Kim, Y. H., Kim, S. K., Hong, S. P., Bae, H., He, Y., Kubota, Y. & Koh, G. Y., 2018 Nov 1, In : The Journal of clinical investigation. 128, 11, p. 5018-5033 16 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Myocardial Infarction
Inflammation
Myocardial Ischemia
Macrophages
6 Citations (Scopus)

Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice

Asami, T., Ishii, M., Namkoong, H., Yagi, K., Tasaka, S., Asakura, T., Suzuki, S., Kamo, T., Okamori, S., Kamata, H., Zhang, H., Hegab, A. E., Hasegawa, N. & Betsuyaku, T., 2018 Mar 1, In : Cytotherapy. 20, 3, p. 302-313 12 p.

Research output: Contribution to journalArticle

Pneumococcal Infections
Mesenchymal Stromal Cells
Anti-Inflammatory Agents
Lung
Streptococcus pneumoniae
1 Citation (Scopus)
Arthropods
Prothrombin
Thrombin
Hemorrhage
Mutation
6 Citations (Scopus)

ApoER2 Controls not only neuronal migration in the intermediate zone but also termination of migration in the developing cerebral cortex

Hirota, Y., Kubo, K., Fujino, T., Yamamoto, T. T. & Nakajima, K., 2018 Jan 1, In : Cerebral Cortex. 28, 1, p. 223-235 13 p.

Research output: Contribution to journalArticle

Cerebral Cortex
Neurons
Neocortex
Brain
Integrins
27 Citations (Scopus)

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Plá, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, Thomas, J. H., Xiao, M., Hirase, H., Asokan, A., Iliff, J. J. & Nedergaard, M., 2018 Dec 1, In : eLife. 7, e40070.

Research output: Contribution to journalArticle

Open Access
Aquaporin 4
Solute transport
Cerebrospinal fluid
Rodentia
Brain
2 Citations (Scopus)

Aspergillus precipitating antibody in patients with Mycobacterium avium complex lung disease: A cross-sectional study

Suzuki, S., Asakura, T., Namkoong, H., Okamori, S., Yagi, K., Kamata, H., Uwamino, Y., Funatsu, Y., Nakano, Y., Nishimura, T., Ishii, M., Ebihara, T., Betsuyaku, T. & Hasegawa, N., 2018 May 1, In : Respiratory Medicine. 138, p. 1-6 6 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Aspergillus
Lung Diseases
Cross-Sectional Studies
Antibodies
2 Citations (Scopus)

Assessing cortical plasticity after spinal cord injury by using resting-state functional magnetic resonance imaging in awake adult mice

Matsubayashi, K., Nagoshi, N., Komaki, Y., Kojima, K., Shinozaki, M., Tsuji, O., Iwanami, A., Ishihara, R., Takata, N., Matsumoto, M., Mimura, M., Okano, H. & Nakamura, M., 2018 Dec 1, In : Scientific Reports. 8, 1, 14406.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Magnetic Resonance Imaging
Gyrus Cinguli
Motivation
Brain
1 Citation (Scopus)

Assessment of mitophagy in iPS cell-derived neurons

Ishikawa, K. I., Yamaguchi, A., Okano, H. & Akamatsu, W., 2018 Jan 1, Methods in Molecular Biology. Humana Press Inc., p. 59-67 9 p. (Methods in Molecular Biology; vol. 1759).

Research output: Chapter in Book/Report/Conference proceedingChapter

Mitochondrial Degradation
Induced Pluripotent Stem Cells
Neurons
Mitochondria
Homeostasis

Association between glycemic control and incident stroke ― Overview from an epidemiologic study

Hirata, T. & Okamura, T., 2018 Jan 1, In : Circulation Journal. 82, 6, p. 1499-1500 2 p.

Research output: Contribution to journalEditorial

Epidemiologic Studies
Stroke
1 Citation (Scopus)

Association between impairment of salty taste recognition and masked hypertension based on home blood pressure in Japanese residents: the KOBE study

Kubota, Y., Higashiyama, A., Sugiyama, D., Nishida, Y., Kubo, S., Hirata, T., Kadota, A., Miyamatsu, N., Wakabayashi, I., Miyamoto, Y. & Okamura, T., 2018 Jan 1, (Accepted/In press) In : Hypertension Research.

Research output: Contribution to journalArticle

Masked Hypertension
Salts
Blood Pressure
Taste Threshold
Recognition (Psychology)
1 Citation (Scopus)

Association between institutional procedural preference and in-hospital outcomes in laparoscopic surgeries; Insights from a retrospective cohort analysis of a nationwide surgical database in Japan

Miyata, H., Mori, M., Kokudo, N., Gotoh, M., Konno, H., Wakabayashi, G., Matsubara, H., Watanabe, T., Ono, M., Hashimoto, H., Yamamoto, H., Kumamaru, H., Kosaka, S. & Iwanaka, T., 2018 Mar 1, In : PLoS One. 13, 3, e0193186.

Research output: Contribution to journalArticle

laparoscopy
Laparoscopy
Surgery
Japan
Cohort Studies
8 Citations (Scopus)

Association Between Knee Pain, Impaired Function, and Development of Depressive Symptoms

Sugai, K., Takeda-Imai, F., Michikawa, T., Nakamura, T., Takebayashi, T. & Nishiwaki, Y., 2018 Jan 1, (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Knee
Depression
Pain
Odds Ratio
Confidence Intervals
2 Citations (Scopus)

Association between programmed cell death ligand-1 expression and extracranial metastasis in intracranial solitary fibrous tumor/hemangiopericytoma

Kamamoto, D., Ohara, K., Kitamura, Y., Yoshida, K., Kawakami, Y. & Sasaki, H., 2018 Apr 19, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Solitary Fibrous Tumors
Hemangiopericytoma
Cell Death
Neoplasm Metastasis
Ligands

Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease

Yagi, K., Asakura, T., Namkoong, H., Suzuki, S., Asami, T., Okamori, S., Kusumoto, T., Funatsu, Y., Kamata, H., Nishimura, T., Ishii, M., Betsuyaku, T. & Hasegawa, N., 2018 Jul 13, In : BMC Pulmonary Medicine. 18, 1, 114.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Quality of Life
Lung
Walk Test
Health Surveys

Association of alcohol consumption and aortic calcification in healthy men aged 40–49 years for the ERA JUMP Study

Mahajan, H., Choo, J., Masaki, K., Fujiyoshi, A., Guo, J., Hisamatsu, T., Evans, R., Shangguan, S., Willcox, B., Okamura, T., Vishnu, A., Barinas-Mitchell, E., Ahuja, V., Miura, K., Kuller, L., Shin, C., Ueshima, H. & Sekikawa, A., 2018 Jan 1, In : Atherosclerosis. 268, p. 84-91 8 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Atherosclerosis
Confounding Factors (Epidemiology)
X Ray Computed Tomography
Asian Americans
3 Citations (Scopus)

Association of blood pressure with estimates of 24-h urinary sodium and potassium excretion from repeated single-spot urine samples

members of the HIPOP-OHP Research Group, 2018 Jan 1, (Accepted/In press) In : Hypertension Research.

Research output: Contribution to journalArticle

Potassium
Sodium
Urine
Blood Pressure
Hypertension
12 Citations (Scopus)

Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH-JAPAN study

Hirata, A., Sugiyama, D., Watanabe, M., Tamakoshi, A., Iso, H., Kotani, K., Kiyama, M., Yamada, M., Ishikawa, S., Murakami, Y., Miura, K., Ueshima, H. & Okamura, T., 2018 Jan 1, (Accepted/In press) In : Journal of Clinical Lipidology.

Research output: Contribution to journalArticle

HDL Cholesterol
Cohort Studies
Mortality
Cardiovascular Diseases
Cause of Death
Independent Living
Cross-Sectional Studies
Exercise
Community Networks
Odds Ratio
3 Citations (Scopus)
Nutrition
Hypercholesterolemia
Social Class
Education
Cholesterol
2 Citations (Scopus)

Associations of high-density lipoprotein particle and high-density lipoprotein cholesterol with alcohol intake, smoking, and body mass index: The INTERLIPID study

INTERLIPID and INTERMAP Research Groups, 2018 Jan 1, In : Circulation Journal. 82, 10, p. 2557-2565 9 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
HDL Cholesterol
Body Mass Index
Smoking
Alcohols
6 Citations (Scopus)

Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase

Hira, K., Ueno, Y., Tanaka, R., Miyamoto, N., Yamashiro, K., Inaba, T., Urabe, T., Okano, H. & Hattori, N., 2018 Oct 1, In : Stroke. 49, 10, p. 2483-2494 12 p.

Research output: Contribution to journalArticle

prostaglandin R2 D-isomerase
Semaphorin-3A
Exosomes
Astrocytes
Stroke
11 Citations (Scopus)

Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition

Wu, R., Murali, R., Kabe, Y., French, S. W., Chiang, Y. M., Liu, S., Sher, L., Wang, C. C., Louie, S. & Tsukamoto, H., 2018 Nov 1, In : Hepatology. 68, 5, p. 1726-1740 15 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Autophagy
Sirolimus
Stem Cells
Liver
2 Citations (Scopus)

Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica

Nurkanto, A., Jeelani, G., Yamamoto, T., Hishiki, T., Naito, Y., Suematsu, M., Hashimoto, T. & Nozaki, T., 2018 Nov 30, In : Frontiers in Microbiology. 9, NOV, 2902.

Research output: Contribution to journalArticle

Entamoeba histolytica
Metabolomics
Coenzymes
Molecular Biology
Parasites