Departments of Basic Medical Sciences

Research Output 1978 2020

2018
5 Citations (Scopus)

Emerging role of D-Amino acid metabolism in the innate defense

Sasabe, J. & Suzuki, M., 2018 May 9, In : Frontiers in Microbiology. 9, MAY, 933.

Research output: Contribution to journalShort survey

Amino Acids
D-Amino-Acid Oxidase
Pattern Recognition Receptors
Bacteria
Phenylalanine

Empleo y salud después de la jubilación en hombres Japoneses

Translated title of the contribution: Employment and health after retirement in Japanese menOkamoto, S., Okamura, T. & Komamura, K., 2018 Dec 1, In : Bulletin of the World Health Organization. 96, 12, p. 826-833 8 p.

Research output: Contribution to journalArticle

Open Access
Retirement
Health
Stroke
Healthy Worker Effect
Men's Health
4 Citations (Scopus)

Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice

Takeda, H., Hosoya, M., Fujioka, M., Saegusa, C., Saeki, T., Miwa, T., Okano, H. & Minoda, R., 2018 Dec 1, In : Scientific Reports. 8, 1, 1941.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Inner Ear
Cell Transplantation
Hearing Loss
Stem Cells

Epidemiology of acute otitis media in children after introduction of the 13-valent pneumococcal conjugate vaccine

Mokuno, E., Morozumi, M., Ubukata, K., Tajima, T. & Iwata, S., 2018 Jan 1, In : Journal of Otolaryngology of Japan. 121, 7, p. 887-898 12 p.

Research output: Contribution to journalArticle

Conjugate Vaccines
Otitis Media
Epidemiology
Haemophilus influenzae
Streptococcus pneumoniae

Epigenome mapping of human normal purified hepatocytes: Personal epigenome variation and genome-epigenome correlation

Arai, E., Miura, F., Totoki, Y., Yamashita, S., Tian, Y., Gotoh, M., Ojima, H., Nakagawa, H., Takahashi, Y., Nakamura, H., Hama, N., Kato, M., Kimura, H., Suzuki, Y., Ito, T., Shibata, T. & Kanai, Y., 2018 Jul 1, In : Epigenomics. 10, 7, p. 955-979 25 p.

Research output: Contribution to journalArticle

Methylation
Hepatocytes
Histone Code
Genome
RNA Sequence Analysis

Erratum: Publisher Correction: Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype (Nature communications (2018) 9 1 (3829))

Hosoi, Y., Soma, M., Shiura, H., Sado, T., Hasuwa, H., Abe, K., Kohda, T., Ishino, F. & Kobayashi, S., 2018 Oct 31, In : Nature Communications. 9, 1, 1 p.

Research output: Contribution to journalComment/debate

Long Noncoding RNA
document markup languages
Microphthalmos
X Chromosome Inactivation
phenotype
1 Citation (Scopus)

Establishment of a human induced stem cell line (FUi002-A) from Dravet syndrome patient carrying heterozygous R1525X mutation in SCN1A gene

Tanaka, Y., Higurashi, N., Shirasu, N., Yasunaga, S., Moreira, K. M., Okano, H. & Hirose, S., 2018 Aug 1, In : Stem Cell Research. 31, p. 11-15 5 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Stem Cells
Fibroblasts
Cell Line
Germ Layers
8 Citations (Scopus)
Conjugate Vaccines
Otitis Media
Streptococcus pneumoniae
Penicillins
Vaccines

Evaluating the quality of data from the Japanese National Clinical Database 2011 via a comparison with regional government report data and medical charts

Tomotaki, A., Kumamaru, H., Hashimoto, H., Takahashi, A., Ono, M., Iwanaka, T. & Miyata, H., 2018 Jan 1, (Accepted/In press) In : Surgery Today.

Research output: Contribution to journalArticle

Databases
Lung
Data Accuracy
Japan
Demography

Evaluation of pancreatic fibrosis with acoustic radiation force impulse imaging and automated quantification of pancreatic tissue components

Fujita, Y., Kitago, M., Abe, T., Itano, O., Shinoda, M., Abe, Y., Yagi, H., Hibi, T., Ishii, M., Nakano, Y., Okuma, K., Hashimoto, M., Takeuchi, A., Masugi, Y., Jinzaki, M., Sakamoto, M. & Kitagawa, Y., 2018 Nov 1, In : Pancreas. 47, 10, p. 1277-1282 6 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Pancreatic Fistula
Fibrosis
Collagen
Acinar Cells

Exposure Assessment in Japan Environment and Children's Study

Nakayama, S. F., Isobe, T., Iwai-Shimada, M., Kobayashi, Y., Oguri, T. & Takeuchi, A., 2018 Jan 1, In : Nihon eiseigaku zasshi. Japanese journal of hygiene. 73, 2, p. 156-163 8 p.

Research output: Contribution to journalReview article

Japan
Environmental Monitoring
Parturition
Hair
Pharmacokinetics
1 Citation (Scopus)

Expression pattern of EYA4 in the common marmoset (Callithrix jacchus) cochlea

Matsuzaki, S., Hosoya, M., Okano, H., Fujioka, M. & Ogawa, K., 2018 Jan 1, In : Neuroscience Letters. 662, p. 185-188 4 p.

Research output: Contribution to journalArticle

Callithrix
Cochlea
Primates
Eustachian Tube
Otitis Media with Effusion
6 Citations (Scopus)

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system

Watanabe, M., Sugiura, Y., Sugiyama, E., Narita, M., Navratilova, E., Kondo, T., Uchiyama, N., Yamanaka, A., Kuzumaki, N., Porreca, F. & Narita, M., 2018 Jan 1, In : Molecular Pain. 14

Research output: Contribution to journalArticle

Microdialysis
Nucleus Accumbens
Mass Spectrometry
Pain
Neurotransmitter Agents
2 Citations (Scopus)

Extracellular vesicle-associated MMPs: A modulator of the tissue microenvironment

Shimoda, M., 2018 Jan 1, (Accepted/In press) In : Advances in Clinical Chemistry.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Modulators
Tissue
Extracellular Matrix Proteins
Body fluids

Factors contributing to salivary human immunodeficiency virus type-1 levels measured by a Poisson distribution-based PCR method

Ikeno, R., Yamada, E., Yamazaki, S., Ueda, T., Nagata, M., Takagi, R. & Kato, S., 2018 Mar 1, In : Journal of International Medical Research. 46, 3, p. 996-1007 12 p.

Research output: Contribution to journalArticle

Poisson Distribution
Poisson distribution
Polymerase chain reaction
Viral Load
Viruses
1 Citation (Scopus)

Factors Related to Participation in Health Examinations for Japanese National Health Insurance: NIPPON DATA2010

Imamura, H., Kogure, M., Kita, Y., Nakagawa, H., Hozawa, A., Okamura, T., Murakami, Y., Nishi, N., Okuda, N., Kadota, A., Ohkubo, T., Ueshima, H., Okayama, A. & Miura, K., 2018 Jan 1, In : Journal of Epidemiology. 28, p. S53-S58

Research output: Contribution to journalArticle

National Health Programs
Ownership
Health Expenditures
Health
Confidence Intervals
1 Citation (Scopus)
Hand-Foot Syndrome
Gastrointestinal Neoplasms
Dermatology
oxaliplatin
Odds Ratio
1 Citation (Scopus)

Fatty liver index predicts incident diabetes in a Japanese general population with and without impaired fasting glucose

Hirata, A., Sugiyama, D., Kuwabara, K., Hirata, T., Tsutatani, H., Funamoto, M., Watanabe, K., Miyamatsu, N. & Okamura, T., 2018 Jan 1, (Accepted/In press) In : Hepatology Research.

Research output: Contribution to journalArticle

Fatty Liver
Fasting
Glucose
Population
Confidence Intervals

Feasibility of methylome analysis using small amounts of genomic DNA from formalin-fixed paraffin-embedded tissue

Ohara, K., Arai, E., Takahashi, Y., Fukamachi, Y., Ito, N., Maeshima, A. M., Fujimoto, H., Yoshida, T. & Kanai, Y., 2018 Nov 1, In : Pathology International. 68, 11, p. 633-635 3 p.

Research output: Contribution to journalLetter

Paraffin
Formaldehyde
DNA
1 Citation (Scopus)

Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis

Nanki, K., Mizuno, S., Matsuoka, K., Ono, K., Sugimoto, S., Kiyohara, H., Arai, M., Nakashima, M., Takeshita, K., Saigusa, K., Senoh, M., Fukuda, T., Naganuma, M., Kato, H., Suda, W., Hattori, M. & Kanai, T., 2018 Jan 1, In : Intestinal Research. 16, 1, p. 142-146 5 p.

Research output: Contribution to journalArticle

Clostridium Infections
Clostridium difficile
Ulcerative Colitis
Dysbiosis
Recurrence
5 Citations (Scopus)

Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease

Kaito, S., Toya, T., Yoshifuji, K., Kurosawa, S., Inamoto, K., Takeshita, K., Suda, W., Kakihana, K., Honda, K., Hattori, M. & Ohashi, K., 2018 Nov 27, In : Blood Advances. 2, 22, p. 3097-3101 5 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Capsules
Fecal Microbiota Transplantation
3 Citations (Scopus)

Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype

Hosoi, Y., Soma, M., Shiura, H., Sado, T., Hasuwa, H., Abe, K., Kohda, T., Ishino, F. & Kobayashi, S., 2018 Dec 1, In : Nature Communications. 9, 1, 3829.

Research output: Contribution to journalArticle

Long Noncoding RNA
Microphthalmos
X Chromosome Inactivation
phenotype
chromosomes

Focal brain lesions induced with ultraviolet irradiation

Nakata, M., Nagasaka, K., Shimoda, M., Takashima, I. & Yamamoto, S., 2018 Dec 1, In : Scientific Reports. 8, 1, 7968.

Research output: Contribution to journalArticle

Brain
Dura Mater
Optical Imaging
Ultraviolet Rays
Neurosciences
2 Citations (Scopus)

Frontotemporal dementia with Parkinsonism linked to chromosome-17 mutations enhance tau oligomer formation

Maeda, S., Sato, Y. & Takashima, A., 2018 Sep 1, In : Neurobiology of Aging. 69, p. 26-32 7 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Chromosomes, Human, Pair 17
Mutation
tau Proteins
Microtubule-Associated Proteins
6 Citations (Scopus)

Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology

Kayama, Y., Shibata, M., Takizawa, T., Ibata, K., Shimizu, T., Ebine, T., Toriumi, H., Yuzaki, M. & Suzuki, N., 2018 Apr 1, In : Cephalalgia. 38, 5, p. 833-845 13 p.

Research output: Contribution to journalArticle

Vasopressin Receptors
Migraine Disorders
Trigeminal Ganglion
Neurons
Pain Threshold
1 Citation (Scopus)

Function and structural regulation of the carbon monoxide (CO)-responsive membrane protein PGRMC1

Kabe, Y., Handa, H. & Suematsu, M., 2018 Jul 1, In : Journal of Clinical Biochemistry and Nutrition. 63, 1, p. 12-17 6 p.

Research output: Contribution to journalReview article

Progesterone Receptors
Carbon Monoxide
Membrane Proteins
Membranes
Heme
6 Citations (Scopus)

Gender-specific association of early age-related macular degeneration with systemic and genetic factors in a Japanese population

Sasaki, M., Harada, S., Kawasaki, Y., Watanabe, M., Ito, H., Tanaka, H., Takeuchi, A., Tsubota, K., Takebayashi, T., Nishiwaki, Y. & Kawasaki, R., 2018 Dec 1, In : Scientific Reports. 8, 1, 785.

Research output: Contribution to journalArticle

Macular Degeneration
Population
Odds Ratio
Confidence Intervals
Sex Factors
3 Citations (Scopus)

Generation and application of human induced-stem cell memory T cells for adoptive immunotherapy

Kondo, T., Imura, Y., Chikuma, S., Hibino, S., Omata-Mise, S., Ando, M., Akanuma, T., Iizuka, M., Sakai, R., Morita, R. & Yoshimura, A., 2018 Jul 1, In : Cancer Science. 109, 7, p. 2130-2140 11 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
Stem Cells
T-Lymphocytes
Cell- and Tissue-Based Therapy
Immunotherapy
4 Citations (Scopus)

Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene

Tanaka, Y., Sone, T., Higurashi, N., Sakuma, T., Suzuki, S., Ishikawa, M., Yamamoto, T., Mitsui, J., Tsuji, H., Okano, H. & Hirose, S., 2018 Apr 1, In : Stem Cell Research. 28, p. 100-104 5 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Induced Pluripotent Stem Cells
Cell Line
NAV1.1 Voltage-Gated Sodium Channel
Brain Diseases
2 Citations (Scopus)

Genome-wide distribution of linker histone H1.0 is independent of MeCP2

Ishida, A., Yamalanchili, H. K., Shao, Y., Baker, S. A., Heckman, L. D., Lavery, L. A., Kim, J. Y., Lombardi, L. M., Sun, Y., Liu, Z. & Zoghbi, H. Y., 2018 Jun 1, In : Nature Neuroscience. 21, 6, p. 794-798 5 p.

Research output: Contribution to journalArticle

Chromatin Immunoprecipitation
Prosencephalon
Histones
Genome
Neurons
1 Citation (Scopus)

Genomic Comparison With Supercentenarians Identifies RNF213 as a Risk Gene for Pulmonary Arterial Hypertension

Suzuki, H., Kataoka, M., Hiraide, T., Aimi, Y., Yamada, Y., Katsumata, Y., Chiba, T., Kanekura, K., Isobe, S., Sato, Y., Satoh, T., Gamou, S., Fukuda, K. & Kosaki, K., 2018 Dec 1, In : Circulation. Genomic and precision medicine. 11, 12, p. e002317

Research output: Contribution to journalLetter

Bone Morphogenetic Protein Receptors
Ubiquitin-Protein Ligases
Pedigree
Genetic Predisposition to Disease
Genomics
1 Citation (Scopus)

Genotypic characterization of Haemophilus influenzae isolates from paediatric patients in Japan

Adachi, Y., Ando, M., Morozumi, M., Ubukata, K. & Iwata, S., 2018 May 1, In : Journal of Medical Microbiology. 67, 5, p. 695-701 7 p., 000721.

Research output: Contribution to journalArticle

Haemophilus influenzae
Otitis Media
Multilocus Sequence Typing
Japan
Pneumonia
18 Citations (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. & 3 others, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 Dec 1, In : Nature Communications. 9, 1, 1561.

Research output: Contribution to journalArticle

Raman Spectrum Analysis
Oxidants
Gold
Raman spectroscopy
tumors
19 Citations (Scopus)

Guidelines for diagnosis and treatment of familial hypercholesterolemia 2017

Working Group by Japan Atherosclerosis Society for Making Guidance of Familial Hypercholesterolemia, 2018 Jan 1, In : Journal of Atherosclerosis and Thrombosis. 25, 8, p. 751-770 20 p.

Research output: Contribution to journalLetter

Hyperlipoproteinemia Type II
Guidelines
Drug therapy
Screening
Tendons

Hand dexterity, not handgrip strength, is associated with executive function in Japanese community-dwelling older adults: A cross-sectional study

Kobayashi-Cuya, K. E., Sakurai, R., Sakuma, N., Suzuki, H., Yasunaga, M., Ogawa, S., Takebayashi, T. & Fujiwara, Y., 2018 Aug 24, In : BMC Geriatrics. 18, 1, 192.

Research output: Contribution to journalArticle

Independent Living
Executive Function
Hand
Cross-Sectional Studies
Trail Making Test
3 Citations (Scopus)

Health-related QOL of elderly patients with pulmonary M. avium complex disease in a university hospital

Asakura, T., Ishii, M., Ishii, K., Suzuki, S., Namkoong, H., Okamori, S., Kamata, H., Yagi, K., Funatsu, Y., Betsuyaku, T. & Hasegawa, N., 2018 Jun 1, In : International Journal of Tuberculosis and Lung Disease. 22, 6, p. 695-703 9 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Quality of Life
Lung
Health
Cross-Sectional Studies
3 Citations (Scopus)

Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells

Si, S., Nakajima-Takagi, Y., Iga, T., Tsuji, M., Hou, L., Oshima, M., Koide, S., Saraya, A., Yamazaki, S., Takubo, K., Kubota, Y., Minamino, T. & Iwama, A., 2018 Jul 1, In : Experimental Hematology. 63, p. 41-51.e1

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Endothelial Cells
Bone Marrow
Blood Vessels
Inflammation
6 Citations (Scopus)

Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology

Zhang, C., Seo, J., Murakami, K., Salem, E. S. B., Bernhard, E., Borra, V. J., Choi, K., Yuan, C. L., Chan, C. C., Chen, X., Huang, T., Weirauch, M. T., Divanovic, S., Qi, N. R., Thomas, H. E., Mercer, C. A., Siomi, H. & Nakamura, T., 2018 Dec 1, In : Nature Communications. 9, 1, 3658.

Research output: Contribution to journalArticle

obesity
AMP-Activated Protein Kinases
metabolism
RNA Interference
Energy Metabolism
3 Citations (Scopus)

HER2 heterogeneity is associated with poor survival in HER2-positive breast cancer

Hosonaga, M., Arima, Y., Sampetrean, O., Komura, D., Koya, I., Sasaki, T., Sato, E., Okano, H., Kudo, J., Ishikawa, S., Saya, H. & Ishikawa, T., 2018 Aug 1, In : International Journal of Molecular Sciences. 19, 8, 2158.

Research output: Contribution to journalArticle

breast
cancer
Breast Neoplasms
mice
RNA Sequence Analysis
9 Citations (Scopus)

Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis

Nishida, K. M., Sakakibara, K., Iwasaki, Y., Yamada, H., Murakami, R., Murota, Y., Kawamura, T., Kodama, T., Siomi, H. & Siomi, M. C., 2018 Mar 8, In : Nature. 555, 7695, p. 260-264 5 p.

Research output: Contribution to journalArticle

Bombyx
Small Interfering RNA
RNA
Exonucleases
Endonucleases
1 Citation (Scopus)

High-Resolution Plasma Membrane-Selective Imaging by Second Harmonic Generation

Mizuguchi, T., Yasui, M. & Nuriya, M., 2018 Nov 30, In : Food Science and Human Wellness. 9, p. 359-366 8 p.

Research output: Contribution to journalArticle

Open Access
plasma membrane
Cell Membrane
image analysis
fluorescence
cell communication
3 Citations (Scopus)

Human amniotic fluid stem cells have a unique potential to accelerate cutaneous wound healing with reduced fibrotic scarring like a fetus

Fukutake, M., Ochiai, D., Masuda, H., Abe, Y., Sato, Y., Otani, T., Sakai, S., Aramaki, N., Shimoda, M., Matsumoto, T., Miyakoshi, K., Kanai, Y., Kishi, K. & Tanaka, M., 2018 Jan 1, (Accepted/In press) In : Human Cell.

Research output: Contribution to journalArticle

Amniotic Fluid
Wound Healing
Cicatrix
Fetus
Stem Cells
7 Citations (Scopus)

Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Is Up-Regulated and Involved in Hyaluronan Degradation in Human Osteoarthritic Cartilage

Shimizu, H., Shimoda, M., Mochizuki, S., Miyamae, Y., Abe, H., Chijiiwa, M., Yoshida, H., Shiozawa, J., Ishijima, M., Kaneko, K., Kanaji, A., Nakamura, M., Toyama, Y. & Okada, Y., 2018 Sep 1, In : American Journal of Pathology. 188, 9, p. 2109-2119 11 p.

Research output: Contribution to journalArticle

CD44 Antigens
Hyaluronic Acid
Cartilage
Chondrocytes
Clathrin Heavy Chains
1 Citation (Scopus)

IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse

Oike, T., Kanagawa, H., Sato, Y., Kobayashi, T., Nakatsukasa, H., Miyamoto, K., Nakamura, S., Kaneko, Y., Kobayashi, S., Harato, K., Yoshimura, A., Iwakura, Y., Takeuchi, T., Matsumoto, M., Nakamura, M., Niki, Y. & Miyamoto, T., 2018 Dec 1, In : Scientific Reports. 8, 1, 15783.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Interleukin-17
Interleukin-6
Joints
Inflammation

Imaging Comparison Between Chinese and Japanese Patients With Cervical Ossification of the Posterior Longitudinal Ligament

Xiao, B., Nagoshi, N., Takeuchi, A., Mao, J., Liu, B., Tian, W., Tsuji, O., Okada, E., Fujita, N., Yagi, M., Nakamura, M., Matsumoto, M., Ishii, K. & Watanabe, K., 2018 Dec 1, In : Spine. 43, 23, p. E1376-E1383

Research output: Contribution to journalArticle

Ossification of Posterior Longitudinal Ligament
Magnetic Resonance Imaging
Multivariate Analysis
Retrospective Studies
Tomography
4 Citations (Scopus)

Immunohistochemical visualization of the signature of activated Hedgehog signaling pathway in cutaneous epithelial tumors

Tanese, K., Emoto, K., Kubota, N., Fukuma, M. & Sakamoto, M., 2018 Jan 1, (Accepted/In press) In : Journal of Dermatology.

Research output: Contribution to journalArticle

Hedgehogs
Staining and Labeling
Basal Cell Carcinoma
Skin
Neoplasms
5 Citations (Scopus)

Impact of resection and ablation for single hypovascular hepatocellular carcinoma ≤2 cm analysed with propensity score weighting

Takayasu, K., Arii, S., Sakamoto, M., Matsuyama, Y., Kudo, M., Kaneko, S., Nakashima, O., Kadoya, M., Izumi, N., Takayama, T., Ku, Y., Kumada, T., Kubo, S., Kokudo, T., Hagiwara, Y. & Kokudo, N., 2018 Jan 1, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Propensity Score
Hepatocellular Carcinoma
Ethanol
Injections
Survival
3 Citations (Scopus)

Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice

Takeuchi, E., Ishida, A., Yuzaki, M. & Yanagihara, D., 2018 Dec 1, In : Scientific Reports. 8, 1, 6184.

Research output: Contribution to journalArticle

Gait Ataxia
Cerebellum
Locomotion
Hindlimb
Purkinje Cells
8 Citations (Scopus)

Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system

Saito, Y., Nakaoka, T., Muramatsu, T., Ojima, H., Sukeda, A., Sugiyama, Y., Uchida, R., Furukawa, R., Kitahara, A., Sato, T., Kanai, Y. & Saito, H., 2018 Dec 1, In : Scientific Reports. 8, 1, 2821.

Research output: Contribution to journalArticle

Organoids
Cholangiocarcinoma
Hepatocytes
Intrahepatic Bile Ducts
Cytochrome P-450 CYP3A
4 Citations (Scopus)

Inhibiting xCT improves 5-fluorouracil resistance of gastric cancer induced by CD44 variant 9 expression

Miyoshi, S., Tsugawa, H., Matsuzaki, J., Hirata, K., Mori, H., Saya, H., Kanai, T. & Suzuki, H., 2018 Nov 1, In : Anticancer Research. 38, 11, p. 6163-6170 8 p.

Research output: Contribution to journalArticle

Fluorouracil
Stomach Neoplasms
Neoplastic Stem Cells
Antiporters
Drug Therapy