Departments of Basic Medical Sciences

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2020

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Mizuno, S., Ono, K., Mikami, Y., Naganuma, M., Fukuda, T., Minami, K., Masaoka, T., Terada, S., Yoshida, T., Saigusa, K., Hirahara, N., Miyata, H., Suda, W., Hattori, M. & Kanai, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Open Access

A case of pancreatic hamartoma with characteristic radiological findings: radiological-pathological correlation

Toyama, K., Matsusaka, Y., Okuda, S., Miura, E., Kubota, N., Masugi, Y., Kitago, M., Hori, S., Yokose, T., Shinoda, M., Sakamoto, M. & Jinzaki, M., 2020 Jan 1, (Accepted/In press) In : Abdominal Radiology.

Research output: Contribution to journalArticle

A Cohort Study of Stereotactic Radiosurgery Results for Patients With 5 to 15 Versus 2 to 4 Brain Metastatic Tumors

Yamamoto, M., Sato, Y., Higuchi, Y., Kasuya, H. & Barfod, B. E., 2020 Jan 1, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

Open Access

Activation of extracellular signal-regulated kinase is associated with hepatocellular carcinoma with aggressive phenotypes

Minagawa, T., Yamazaki, K., Masugi, Y., Tsujikawa, H., Ojima, H., Hibi, T., Abe, Y., Yagi, H., Kitago, M., Shinoda, M., Itano, O., Kitagawa, Y. & Sakamoto, M., 2020 Mar 1, In : Hepatology Research. 50, 3, p. 353-364 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ADAM10 is indispensable for longitudinal bone growth in mice

Mizuno, S., Yoda, M., Kimura, T., Shimoda, M., Akiyama, H., Chiba, K., Nakamura, M. & Horiuchi, K., 2020 May, In : Bone. 134, 115273.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Adherence to antihypertensive medication and its predictors among non-elderly adults in Japan

Nishimura, S., Kumamaru, H., Shoji, S., Sawano, M., Kohsaka, S. & Miyata, H., 2020 Jan 1, (Accepted/In press) In : Hypertension Research.

Research output: Contribution to journalArticle

Analysis of the nucleocytoplasmic shuttling RNA-binding protein HNRNPU using optimized HITS-CLIP method

Yugami, M., Okano, H., Nakanishi, A. & Yano, M., 2020 Apr, In : PloS one. 15, 4, e0231450.

Research output: Contribution to journalArticle

Open Access

A nationwide questionnaire survey of clinic doctors on antimicrobial stewardship in Japan

Gu, Y., Fujitomo, Y., Soeda, H., Nakahama, C., Hasegawa, N., Maesaki, S., Maeda, M., Matsumoto, T., Miyairi, I. & Ohmagari, N., 2020 Feb, In : Journal of Infection and Chemotherapy. 26, 2, p. 149-156 8 p.

Research output: Contribution to journalArticle

An improved de novo genome assembly of the common marmoset genome yields improved contiguity and increased mapping rates of sequence data

Jayakumar, V., Ishii, H., Seki, M., Kumita, W., Inoue, T., Hase, S., Sato, K., Okano, H., Sasaki, E. & Sakakibara, Y., 2020 Apr 2, In : BMC Genomics. 21, 243.

Research output: Contribution to journalArticle

Open Access

Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites

Kabe, Y., Takemoto, D., Kanai, A., Hirai, M., Ono, Y., Akazawa, S., Horikawa, M., Kitagawa, Y., Handa, H., Rogi, T., Shibata, H. & Suematsu, M., 2020 Dec 1, In : npj Science of Food. 4, 1, 4.

Research output: Contribution to journalArticle

Open Access

Armitage determines Piwi−piRISC processing from precursor formation and quality control to inter-organelle translocation

Yamashiro, H., Negishi, M., Kinoshita, T., Ishizu, H., Ohtani, H. & Siomi, M. C., 2020 Feb 5, In : EMBO Reports. 21, 2, e48769.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association between Asian dust exposure and respiratory function in children with bronchial asthma in Nagasaki Prefecture, Japan

Nakamura, T., Nishiwaki, Y., Hashimoto, K., Takeuchi, A., Kitajima, T., Komori, K., Tashiro, K., Hasunuma, H., Ueda, K., Shimizu, A., Odajima, H., Moriuchi, H. & Hashizume, M., 2020 Mar 4, In : Environmental Health and Preventive Medicine. 25, 1, 8.

Research output: Contribution to journalArticle

Open Access

Association between prehospital transfer distance and surgical mortality in emergency thoracic aortic surgery

Izumisawa, Y., Endo, H., Ichihara, N., Takahashi, A., Nawata, K., Shiraishi, H., Miyata, H. & Motomura, N., 2020 Jan 1, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

Association of autophagy status with amount of Fusobacterium nucleatum in colorectal cancer

Haruki, K., Kosumi, K., Hamada, T., Twombly, T. S., Väyrynen, J. P., Kim, S. A., Masugi, Y., Qian, Z. R., Mima, K., Baba, Y., da Silva, A., Borowsky, J., Arima, K., Fujiyoshi, K., Lau, M. C., Li, P., Guo, C., Chen, Y., Song, M., Nowak, J. A. & 12 others, Nishihara, R., Yanaga, K., Zhang, X., Wu, K., Bullman, S., Garrett, W. S., Huttenhower, C., Meyerhardt, J. A., Giannakis, M., Chan, A. T., Fuchs, C. S. & Ogino, S., 2020 Apr 1, In : Journal of Pathology. 250, 4, p. 397-408 12 p.

Research output: Contribution to journalArticle

Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Hayashi, K., Hishikawa, A., Hashiguchi, A., Azegami, T., Yoshimoto, N., Nakamichi, R., Tokuyama, H. & Itoh, H., 2020 Dec 1, In : Scientific reports. 10, 1, 237.

Research output: Contribution to journalArticle

Open Access

Awake functional MRI detects neural circuit dysfunction in a mouse model of autism

Tsurugizawa, T., Tamada, K., Ono, N., Karakawa, S., Kodama, Y., Debacker, C., Hata, J., Okano, H., Kitamura, A., Zalesky, A. & Takumi, T., 2020 Feb 5, In : Science Advances. 6, 6, eaav4520.

Research output: Contribution to journalArticle

Open Access

Blood metabolite signature of metabolic syndrome implicates alterations in amino acid metabolism: Findings from the baltimore longitudinal study of aging (blsa) and the tsuruoka metabolomics cohort study (TMCS)

Roberts, J. A., Varma, V. R., Huang, C. W., An, Y., Oommen, A., Tanaka, T., Ferrucci, L., Elango, P., Takebayashi, T., Harada, S., Iida, M. & Thambisetty, M., 2020 Feb, In : International journal of molecular sciences. 21, 4, 1249.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Blood metabolite signatures of metabolic syndrome in two cross-cultural older adult cohorts

Mahajan, U. V., Varma, V. R., Huang, C. W., An, Y., Tanaka, T., Ferrucci, L., Takebayashi, T., Harada, S., Iida, M., Legido-Quigley, C. & Thambisetty, M., 2020 Feb 2, In : International journal of molecular sciences. 21, 4, 1324.

Research output: Contribution to journalArticle

Open Access

Characteristics of leiomyosarcoma: Induction of hematogenous metastasis by isolated uterine mesenchymal tumor stem-like cells

Hayashi, T., Sano, K., Ichimura, T., Kanai, Y., Zharhary, D., Aburatani, H., Yaegashi, N. & Konishi, I., 2020 Jan 1, In : Anticancer research. 40, 3, p. 1255-1265 11 p.

Research output: Contribution to journalArticle

Open Access

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

Grandjean, J., Canella, C., Anckaerts, C., Ayrancı, G., Bougacha, S., Bienert, T., Buehlmann, D., Coletta, L., Gallino, D., Gass, N., Garin, C. M., Nadkarni, N. A., Hübner, N. S., Karatas, M., Komaki, Y., Kreitz, S., Mandino, F., Mechling, A. E., Sato, C., Sauer, K. & 28 others, Shah, D., Strobelt, S., Takata, N., Wank, I., Wu, T., Yahata, N., Yeow, L. Y., Yee, Y., Aoki, I., Chakravarty, M. M., Chang, W. T., Dhenain, M., von Elverfeldt, D., Harsan, L. A., Hess, A., Jiang, T., Keliris, G. A., Lerch, J. P., Meyer-Lindenberg, A., Okano, H., Rudin, M., Sartorius, A., Van der Linden, A., Verhoye, M., Weber-Fahr, W., Wenderoth, N., Zerbi, V. & Gozzi, A., 2020 Jan 15, In : NeuroImage. 205, 116278.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Contemporary outcomes of surgical aortic valve replacement in Japan

Japan Cardiovascular Surgery Database Organization, 2020 Jan 1, In : Circulation Journal. 84, 2, p. 277-282 6 p.

Research output: Contribution to journalArticle

Open Access

Corneal higher-order aberrations in eyes with chronic ocular graft-versus-host disease

Shimizu, E., Aketa, N., Yazu, H., Uchino, M., Kamoi, M., Sato, Y., Tsubota, K. & Ogawa, Y., 2020 Jan, In : Ocular Surface. 18, 1, p. 98-107 10 p.

Research output: Contribution to journalArticle

Crystal structure of Drosophila Piwi

Yamaguchi, S., Oe, A., Nishida, K. M., Yamashita, K., Kajiya, A., Hirano, S., Matsumoto, N., Dohmae, N., Ishitani, R., Saito, K., Siomi, H., Nishimasu, H., Siomi, M. C. & Nureki, O., 2020 Dec 1, In : Nature communications. 11, 1, 858.

Research output: Contribution to journalArticle

Open Access

Dietary inflammatory index positively associated with high-sensitivity C-reactive protein level in Japanese from NIPPON data2010

NIPPON DATA2010 Research Group, 2020 Jan 1, In : Journal of epidemiology. 30, 2, p. 98-107 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets

Wagatsuma, T., Nagai-Okatani, C., Matsuda, A., Masugi, Y., Imaoka, M., Yamazaki, K., Sakamoto, M. & Kuno, A., 2020 Mar 13, In : Frontiers in Oncology. 10, 338.

Research output: Contribution to journalArticle

Open Access

Distribution of tight junctions in the primate cochlear lateral wall

Saeki, T., Hosoya, M., Shibata, S., Okano, H., Fujioka, M. & Ogawa, K., 2020 Jan 19, In : Neuroscience Letters. 717, 134686.

Research output: Contribution to journalArticle

Echocardiographic Parameters and the Risk of Incident Atrial Fibrillation: The Suita Study

Higashiyama, A., Kokubo, Y., Watanabe, M., Nakao, Y. M., Okamura, T., Okayama, A. & Miyamoto, Y., 2020 Apr 5, In : Journal of epidemiology. 30, 4, p. 183-187 5 p.

Research output: Contribution to journalArticle

Open Access

Effect of increased daily water intake and hydration on health in Japanese adults

Nakamura, Y., Watanabe, H., Tanaka, A., Yasui, M., Nishihira, J. & Murayama, N., 2020 Apr, In : Nutrients. 12, 4, 1191.

Research output: Contribution to journalArticle

Open Access

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., Okano, H., Nabeshima, Y. I., Imai, S. I., Yasui, M., Tsubota, K. & Itoh, H., 2020 Jan 1, In : Endocrine journal. 67, 2, p. 153-160 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Effect of surgical margin width after R0 resection for intrahepatic cholangiocarcinoma: A nationwide survey of the Liver Cancer Study Group of Japan

Watanabe, Y., Matsuyama, Y., Izumi, N., Kubo, S., Kokudo, N., Sakamoto, M., Shiina, S., Takayama, T., Nakashima, O. & Kudo, M., 2020 May, In : Surgery (United States). 167, 5, p. 793-802 10 p.

Research output: Contribution to journalArticle

Effects of Cardiac Surgery and Salvaged Blood Transfusion on Coagulation Function Assessed by Thromboelastometry

Son, K., Yamada, T., Tarao, K., Kitamura, Y., Okazaki, J., Sato, Y. & Isono, S., 2020 Jan 1, (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Electrocardiographic ST-T Abnormities Are Associated with Stroke Risk in the REGARDS Study

Sawano, M., Yuan, Y., Kohsaka, S., Inohara, T., Suzuki, T., Okamura, T., Howard, G., Howard, V. J., Judd, S., Soliman, E. Z. & Cushman, M., 2020 Apr 1, In : Stroke. p. 1100-1106 7 p.

Research output: Contribution to journalArticle

Open Access

Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth

Zagato, E., Pozzi, C., Bertocchi, A., Schioppa, T., Saccheri, F., Guglietta, S., Fosso, B., Melocchi, L., Nizzoli, G., Troisi, J., Marzano, M., Oresta, B., Spadoni, I., Atarashi, K., Carloni, S., Arioli, S., Fornasa, G., Asnicar, F., Segata, N., Guglielmetti, S. & 5 others, Honda, K., Pesole, G., Vermi, W., Penna, G. & Rescigno, M., 2020 Mar 1, In : Nature Microbiology. 5, 3, p. 511-524 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

FOXO1 regulates developmental lymphangiogenesis by upregulating CXCR4 in the mouse-tail dermis

Niimi, K., Kohara, M., Sedoh, E., Fukumoto, M., Shibata, S., Sawano, T., Tashiro, F., Miyazaki, S., Kubota, Y., Miyazaki, J. I., Inagaki, S. & Furuyama, T., 2020 Jan 1, In : Development (Cambridge). 147, 2, dev181545.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Generation of a male common marmoset embryonic stem cell line DSY127-BV8VT1 carrying double reporters specific for the germ cell linage using the CRISPR-Cas9 and PiggyBac transposase systems

Yoshimatsu, S., Sato, T., Yamamoto, M., Sasaki, E., Nakajima, M., Nakamura, M., Shiozawa, S., Noce, T. & Okano, H., 2020 Apr, In : Stem Cell Research. 44, 101740.

Research output: Contribution to journalArticle

Open Access

Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect

Tamura, R., Miyoshi, H., Morimoto, Y., Oishi, Y., Sampetrean, O., Iwasawa, C., Mine, Y., Saya, H., Yoshida, K., Okano, H. & Toda, M., 2020 Mar, In : Human Gene Therapy. 31, 5-6, p. 352-366 15 p.

Research output: Contribution to journalArticle

Open Access

Hidden disseminated extracutaneous AIDS-related Kaposi sarcoma

Kawakami, N., Namkoong, H., Shimoda, M., Kotani, H., Fujiwara, H. & Hasegawa, N., 2020, In : IDCases. 19, e00716.

Research output: Contribution to journalArticle

Open Access

How I do it: Endoscopic diagnosis for superficial non-ampullary duodenal epithelial tumors

Nakayama, A., Kato, M., Takatori, Y., Shimoda, M., Mizutani, M., Tsutsumi, K., Kiguchi, Y., Akimoto, T., Sasaki, M., Mutaguchi, M., Takabayashi, K., Maehata, T., Ochiai, Y., Kanai, T. & Yahagi, N., 2020 Mar 1, In : Digestive Endoscopy. 32, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection

Dokoshi, T., Zhang, L. J., Li, F., Nakatsuji, T., Butcher, A., Yoshida, H., Shimoda, M., Okada, Y. & Gallo, R. L., 2020 Jan 7, In : Cell Reports. 30, 1, p. 61-68.e4

Research output: Contribution to journalArticle

Open Access

Hypercholesterolemia and lifetime risk of coronary heart disease in the general japanese population: Results from the suita cohort study

Sugiyama, D., Turin, T. C., Yeasmin, F., Rumana, N., Watanabe, M., Higashiyama, A., Takegami, M., Kokubo, Y., Okamura, T. & Miyamoto, Y., 2020 Jan 1, In : Journal of atherosclerosis and thrombosis. 27, 1, p. 60-70 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

IL-6 and G-CSF production resulting from lung cancer in an HIV patient

Kawakami, N., Namkoong, H., Masaki, K., Kurebayashi, Y., Shimoda, M., Kotani, H., Fujiwara, H. & Hasegawa, N., 2020, In : IDCases. 19, e00693.

Research output: Contribution to journalArticle

Open Access

Impact of adherence to board-certified surgeon systems and clinical practice guidelines on colon cancer surgical outcomes in Japan: A questionnaire survey of the National Clinical Database

Kobayashi, H., Yamamoto, H., Miyata, H., Gotoh, M., Kotake, K., Sugihara, K., Toh, Y., Kakeji, Y. & Seto, Y., 2020 Jan 1, (Accepted/In press) In : Annals of Gastroenterological Surgery.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study

Nagoshi, N., Kono, H., Tsuji, O., Aoyama, R., Fujiyoshi, K., Shiono, Y., Ishikawa, M., Daimon, K., Hosogane, N., Takeuchi, A., Okada, E., Fujita, N., Yagi, M., Nakamura, M., Matsumoto, M., Watanabe, K., Ishii, K. & Yamane, J., 2020 Jan 1, (Accepted/In press) In : Clinical Spine Surgery.

Research output: Contribution to journalArticle

Impaired glucose tolerance and future cardiovascular risk after coronary revascularization: a 10-year follow-up report

Tsuchida, K., Mitsuma, W., Sato, Y., Ozaki, K., Soda, S., Hatada, K., Tanaka, K., Hosaka, Y., Imai, S., Takahashi, K., Matsubara, T. & Oda, H., 2020 Feb 1, In : Acta Diabetologica. 57, 2, p. 173-182 10 p.

Research output: Contribution to journalArticle

Importance of Distal Sealing during Endovascular Aneurysm Repair Using Aneurysmal Common Iliac Artery as Landing Zone

Shintani, T., Mitsuoka, H., Hasegawa, Y., Hayashi, M., Natsume, K., Ookura, K., Sato, Y. & Obara, H., 2020 Jan 1, (Accepted/In press) In : Annals of Vascular Surgery.

Research output: Contribution to journalArticle

Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma

Shima, T., Shimoda, M., Shigenobu, T., Ohtsuka, T., Nishimura, T., Emoto, K., Hayashi, Y., Iwasaki, T., Abe, T., Asamura, H. & Kanai, Y., 2020 Feb 1, In : Cancer science. 111, 2, p. 727-738 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

International Brain Initiative: An Innovative Framework for Coordinated Global Brain Research Efforts

International Brain Initiative, 2020 Jan 22, In : Neuron. 105, 2, p. 212-216 5 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

In vivo monitoring of remnant undifferentiated neural cells following human induced pluripotent stem cell-derived neural stem/progenitor cells transplantation

Tanimoto, Y., Yamasaki, T., Nagoshi, N., Nishiyama, Y., Nori, S., Nishimura, S., Iida, T., Ozaki, M., Tsuji, O., Ji, B., Aoki, I., Jinzaki, M., Matsumoto, M., Fujibayashi, Y., Zhang, M. R., Nakamura, M. & Okano, H., 2020 Apr 1, In : Stem Cells Translational Medicine. 9, 4, p. 465-477 13 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)