Departments of Basic Medical Sciences

Research Output 1978 2020

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Letter
2019
24 Citations (Scopus)

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

Ito, M., Komai, K., Mise-Omata, S., Iizuka-Koga, M., Noguchi, Y., Kondo, T., Sakai, R., Matsuo, K., Nakayama, T., Yoshie, O., Nakatsukasa, H., Chikuma, S., Shichita, T. & Yoshimura, A., 2019 Jan 10, In : Nature. 565, 7738, p. 246-250 5 p.

Research output: Contribution to journalLetter

Regulatory T-Lymphocytes
Brain
Stroke
Chemokine CCL1
Chemokine CCL20

Effect of empagliflozin on endothelial function in patients with type 2 diabetes and cardiovascular disease: Results from the multicenter, randomized, placebo- controlled, double-blind EMBLEM trial

Tanaka, A., Shimabukuro, M., MacHii, N., Teragawa, H., Okada, Y., Shima, K. R., Takamura, T., Taguchi, I., Hisauchi, I., Toyoda, S., Matsuzawa, Y., Tomiyama, H., Yamaoka-Tojo, M., Yoshida, H., Sato, Y., Ikehara, Y., Ueda, S., Higashi, Y. & Node, K., 2019 Oct 1, In : Diabetes care. 42, 10, p. E159-E161

Research output: Contribution to journalLetter

Open Access
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Placebos
empagliflozin

Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus

Kim, S. G., Becattini, S., Moody, T. U., Shliaha, P. V., Littmann, E. R., Seok, R., Gjonbalaj, M., Eaton, V., Fontana, E., Amoretti, L., Wright, R., Caballero, S., Wang, Z. M. X., Jung, H. J., Morjaria, S. M., Leiner, I. M., Qin, W., Ramos, R. J. J. F., Cross, J. R., Narushima, S. & 6 others, Honda, K., Peled, J. U., Hendrickson, R. C., Taur, Y., van den Brink, M. R. M. & Pamer, E. G., 2019 Aug 29, In : Nature. 572, 7771, p. 665-669 5 p.

Research output: Contribution to journalLetter

Enterococcus faecium
Bacteriocins
Microbiota
Lactococcus lactis
Bacteria
21 Citations (Scopus)

NR4A transcription factors limit CAR T cell function in solid tumours

Chen, J., López-Moyado, I. F., Seo, H., Lio, C. W. J., Hempleman, L. J., Sekiya, T., Yoshimura, A., Scott-Browne, J. P. & Rao, A., 2019 Mar 28, In : Nature. 567, 7749, p. 530-534 5 p.

Research output: Contribution to journalLetter

Transcription Factors
T-Lymphocytes
Tumor-Infiltrating Lymphocytes
Neoplasms
Chromatin
2018

Cardiometabolic index as a useful discriminator for the risk of increased arterial stiffness

Wakabayashi, I., Marumo, M., Kubota, Y., Higashiyama, A., Miyamoto, Y. & Okamura, T., 2018 Nov 1, In : Clinica Chimica Acta. 486, p. 42-43 2 p.

Research output: Contribution to journalLetter

Discriminators
HDL Lipoproteins
LDL Lipoproteins
Stiffness

Feasibility of methylome analysis using small amounts of genomic DNA from formalin-fixed paraffin-embedded tissue

Ohara, K., Arai, E., Takahashi, Y., Fukamachi, Y., Ito, N., Maeshima, A. M., Fujimoto, H., Yoshida, T. & Kanai, Y., 2018 Nov 1, In : Pathology International. 68, 11, p. 633-635 3 p.

Research output: Contribution to journalLetter

Paraffin
Formaldehyde
DNA
1 Citation (Scopus)

Genomic Comparison With Supercentenarians Identifies RNF213 as a Risk Gene for Pulmonary Arterial Hypertension

Suzuki, H., Kataoka, M., Hiraide, T., Aimi, Y., Yamada, Y., Katsumata, Y., Chiba, T., Kanekura, K., Isobe, S., Sato, Y., Satoh, T., Gamou, S., Fukuda, K. & Kosaki, K., 2018 Dec 1, In : Circulation. Genomic and precision medicine. 11, 12, p. e002317

Research output: Contribution to journalLetter

Bone Morphogenetic Protein Receptors
Ubiquitin-Protein Ligases
Pedigree
Genetic Predisposition to Disease
Genomics
17 Citations (Scopus)

Guidelines for diagnosis and treatment of familial hypercholesterolemia 2017

Working Group by Japan Atherosclerosis Society for Making Guidance of Familial Hypercholesterolemia, 2018 Jan 1, In : Journal of Atherosclerosis and Thrombosis. 25, 8, p. 751-770 20 p.

Research output: Contribution to journalLetter

Hyperlipoproteinemia Type II
Guidelines
Drug therapy
Screening
Tendons
1 Citation (Scopus)

Mycobacterium triplex pulmonary disease with acquired macrolide resistance in immunocompetent patients

Matsuda, S., Suzuki, S., Morimoto, K., Aono, A., Nishio, K., Asakura, T., Sasaki, Y., Namkoong, H., Nishimura, T., Ogata, H., Hasegawa, N., Kurashima, A., Ishii, M., Tatsumi, K., Mitarai, S. & Goto, H., 2018 Jun 1, In : Clinical Microbiology and Infection. 24, 6, p. 671-672 2 p.

Research output: Contribution to journalLetter

Macrolides
Mycobacterium
Lung Diseases
2017

A novel diagnostic biomarker for human uterine leiomyosarcoma: PSMB9/β1i

Hayashi, T., Kawano, M., Sano, K., Ichimura, T., Gur, G., Yaish, P., Zharhary, D., Kanai, Y., Tonegawa, S., Shiozawa, T., Yaegashi, N. & Konishi, I., 2017 Apr 1, In : Chinese Clinical Oncology. 6, 2, p. 1-3 3 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)

Excessive activation of AhR signaling disrupts neuronal migration in the hippocampal CA1 region in the developing mouse

Kimura, E., Kubo, K., Endo, T., Nakajima, K., Kakeyama, M. & Tohyama, C., 2017, In : Journal of Toxicological Sciences. 42, 1, p. 25-30 6 p.

Research output: Contribution to journalLetter

Hippocampal CA1 Region
Aryl Hydrocarbon Receptors
Chemical activation
Dioxins
Xenobiotics

The dual effects of the astrocyte-specific enhancer of the AQP4 M1 promoter

Abe, Y., Goda, W., Ikeshima-Kataoka, H. & Yasui, M., 2017 Dec 1, In : FEBS Letters. 591, 23, p. 3906-3915 10 p.

Research output: Contribution to journalLetter

Astrocytes
Aquaporin 4
Aquaporins
Neurology
Exons
2016

A case of atypical inflammatory myositis with hypergammaglobulinemic purpura

Nihei, Y., Tanikawa, M., Seki, M., Suzuki, S., Tanikawa, A., Ohara, K., Miyamoto, K., Matsubara, S. & Suzuki, N., 2016 Aug 15, In : Journal of the Neurological Sciences. 367, p. 275-277 3 p.

Research output: Contribution to journalLetter

Hyperglobulinemic Purpura
Myositis
Purpura
Sjogren's Syndrome
Leg

Effect of Pre-Procedural Beta-Blocker in Patients Undergoing Percutaneous Coronary Intervention

Maekawa, Y., Miyata, H., Ueda, I., Ikemura, N., Fukuda, K. & Kohsaka, S., 2016 Dec 12, In : JACC: Cardiovascular Interventions. 9, 23, p. 2458-2459 2 p.

Research output: Contribution to journalLetter

Percutaneous Coronary Intervention
2015
3 Citations (Scopus)

Biological characterization of soft tissue sarcomas

Hayashi, T., Horiuchi, A., Sano, K., Kanai, Y., Yaegashi, N., Aburatani, H. & Konishi, I., 2015 Dec 1, In : Annals of Translational Medicine. 3, 22, 368.

Research output: Contribution to journalLetter

Sarcoma
Neoplasms
Biomarkers
Retinoblastoma
Gene Amplification
2 Citations (Scopus)

Reply to Farkouh RA et al. Comment on “Cost-Effectiveness Evaluation of the 10-Valent Pneumococcal Non-Typeable Haemophilus Influenzae Protein D Conjugate Vaccine and 13-Valent Pneumococcal Vaccine in Japanese Children”

Shiragami, M., Mizukami, A., Leeuwenkamp, O., Mrkvan, T., Delgleize, E., Kurono, Y. & Iwata, S., 2015 Jun 19, In : Infectious Diseases and Therapy. 4, 2, p. 235-244 10 p.

Research output: Contribution to journalLetter

Conjugate Vaccines
Cost-Benefit Analysis
Haemophilus influenzae glpQ protein
13-valent pneumococcal vaccine