Departments of Basic Medical Sciences

Research Output

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Review article
2020

Human amyloidosis, still intractable but becoming curable: The essential role of pathological diagnosis in the selection of type-specific therapeutics

Naiki, H., Sekijima, Y., Ueda, M., Ohashi, K., Hoshii, Y., Shimoda, M. & Ando, Y., 2020 Apr 1, In : Pathology international. 70, 4, p. 191-198 8 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

In situ imaging of monoamine localization and dynamics

Sugiyama, E., Skelly, A. N., Suematsu, M. & Sugiura, Y., 2020 Apr, In : Pharmacology and Therapeutics. 208, 107478.

Research output: Contribution to journalReview article

Precision pathology analysis of the development and progression of hepatocellular carcinoma: Implication for precision diagnosis of hepatocellular carcinoma

Ueno, A., Masugi, Y., Yamazaki, K., Kurebayashi, Y., Tsujikawa, H., Effendi, K., Ojima, H. & Sakamoto, M., 2020 Mar 1, In : Pathology international. 70, 3, p. 140-154 15 p.

Research output: Contribution to journalReview article

Regulation of AQP4 in the central nervous system

Vandebroek, A. & Yasui, M., 2020 Mar, In : International journal of molecular sciences. 21, 5, 1603.

Research output: Contribution to journalReview article

Open Access

Regulatory T cells: Pathophysiological roles and clinical applications

Sakai, R., Komai, K., Iizuka-Koga, M., Yoshimura, A. & Ito, M., 2020 Jan 1, In : Keio Journal of Medicine. 69, 1, p. 1-15 15 p.

Research output: Contribution to journalReview article

Open Access

Ropinirole, a New ALS Drug Candidate Developed Using iPSCs

Okano, H., Yasuda, D., Fujimori, K., Morimoto, S. & Takahashi, S., 2020 Jan 1, (Accepted/In press) In : Trends in Pharmacological Sciences.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Thoracic and cardiovascular surgeries in Japan during 2017: Annual report by the Japanese Association for Thoracic Surgery

Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery, 2020 Apr 1, In : General thoracic and cardiovascular surgery. 68, 4, p. 414-449 36 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)
2019

Application of high-performance magnetic nanobeads to biological sensing devices

Kabe, Y., Sakamoto, S., Hatakeyama, M., Yamaguchi, Y., Suematsu, M., Itonaga, M. & Handa, H., 2019 Mar 16, In : Analytical and bioanalytical chemistry. 411, 9, p. 1825-1837 13 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Are We There Yet? How and When Specific Biotechnologies Will Improve Human Health

O'Day, E., Hosta-Rigau, L., Oyarzún, D. A., Okano, H., de Lorenzo, V., von Kameke, C., Alsafar, H., Cao, C., Chen, G. Q., Ji, W., Roberts, R. J., Ronaghi, M., Yeung, K., Zhang, F. & Lee, S. Y., 2019 Jan, In : Biotechnology Journal. 14, 1, 1800195.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Can cognitive leisure activity prevent cognitive decline in older adults? A systematic review of intervention studies

Iizuka, A., Suzuki, H., Ogawa, S., Kobayashi-Cuya, K. E., Kobayashi, M., Takebayashi, T. & Fujiwara, Y., 2019 Jan 1, In : Geriatrics and Gerontology International.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Cell therapy for spinal cord injury using induced pluripotent stem cells

Nagoshi, N., Tsuji, O., Nakamura, M. & Okano, H., 2019 Dec 1, In : Regenerative Therapy. 11, p. 75-80 6 p.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)

Concise Review: Laying the Groundwork for a First-In-Human Study of an Induced Pluripotent Stem Cell-Based Intervention for Spinal Cord Injury

Tsuji, O., Sugai, K., Yamaguchi, R., Tashiro, S., Nagoshi, N., Kohyama, J., Iida, T., Ohkubo, T., Itakura, G., Isoda, M., Shinozaki, M., Fujiyoshi, K., Kanemura, Y., Yamanaka, S., Nakamura, M. & Okano, H., 2019 Jan, In : Stem Cells. 37, 1, p. 6-13 8 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Current status of cardiovascular surgery in Japan: analysis of data from Japan Cardiovascular Surgery Database in 2015, 2016. 3—Valvular heart surgery

Abe, T., Nakano, K., Hirahara, N., Motomura, N., Miyata, H. & Takamoto, S., 2019 Sep 5, In : General thoracic and cardiovascular surgery. 67, 9, p. 742-749 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2 Citations (Scopus)

Current status of cardiovascular surgery in Japan, 2015 and 2016: a report based on the Japan Cardiovascular Surgery Database. 1—congenital heart surgery

Hirata, Y., Hirahara, N., Murakami, A., Motomura, N., Miyata, H. & Takamoto, S., 2019 Sep 5, In : General thoracic and cardiovascular surgery. 67, 9, p. 731-735 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
1 Citation (Scopus)

Distinctive roles of d-Amino acids in the homochiral world: Chirality of amino acids modulates mammalian physiology and pathology

Sasabe, J. & Suzuki, M., 2019 Jan 1, In : Keio Journal of Medicine. 68, 1, p. 1-16 16 p.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)
Open Access

Memory T cell, exhaustion, and tumor immunity

Ando, M., Ito, M., Srirat, T., Kondo, T. & Yoshimura, A., 2019 Jan 1, (Accepted/In press) In : Immunological Medicine.

Research output: Contribution to journalReview article

Open Access

Mining the microbiota for microbial and metabolite-based immunotherapies

Skelly, A. N., Sato, Y., Kearney, S. & Honda, K., 2019 Jan 1, In : Nature Reviews Immunology.

Research output: Contribution to journalReview article

34 Citations (Scopus)

Modeling Familial Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells

Tabata, Y. & Okano, H., 2019 Aug 1, In : Brain and nerve = Shinkei kenkyu no shinpo. 71, 8, p. 875-883 9 p.

Research output: Contribution to journalReview article

Recent progress in the research of suicide gene therapy for malignant glioma

Tamura, R., Miyoshi, H., Yoshida, K., Okano, H. & Toda, M., 2019 Jan 1, (Accepted/In press) In : Neurosurgical Review.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Role of the Immune System in the Development of the Central Nervous System

Morimoto, K. & Nakajima, K., 2019 Sep 3, In : Frontiers in Neuroscience. 13, 916.

Research output: Contribution to journalReview article

Open Access
6 Citations (Scopus)

The Sprouty/Spred family as tumor suppressors: Coming of age

Kawazoe, T. & Taniguchi, K., 2019 May, In : Cancer science. 110, 5, p. 1525-1535 11 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Update of occupational lung disease

Japan Society for Occupational Health Occupational Lung Disease Study Group, 2019 Jan 1, In : Journal of Occupational Health. 61, 1, p. 10-18 9 p.

Research output: Contribution to journalReview article

2018

Development and Functional Modulation of Regulatory T Cells by Transcription Factors and Epigenetics

Ito, M., Iizuka-Koga, M., Ando, M. & Yoshimura, A., 2018 Nov 1, In : Cornea. 37, p. S42-S49

Research output: Contribution to journalReview article

1 Citation (Scopus)

Exposure Assessment in Japan Environment and Children's Study

Nakayama, S. F., Isobe, T., Iwai-Shimada, M., Kobayashi, Y., Oguri, T. & Takeuchi, A., 2018 Jan 1, In : Nihon eiseigaku zasshi. Japanese journal of hygiene. 73, 2, p. 156-163 8 p.

Research output: Contribution to journalReview article

Function and structural regulation of the carbon monoxide (CO)-responsive membrane protein PGRMC1

Kabe, Y., Handa, H. & Suematsu, M., 2018 Jul, In : Journal of Clinical Biochemistry and Nutrition. 63, 1, p. 12-17 6 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Investigation of brain science and neurological/psychiatric disorders using genetically modified non-human primates

Okano, H. & Kishi, N., 2018 Jun, In : Current Opinion in Neurobiology. 50, p. 1-6 6 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

NF-B, inflammation, immunity and cancer: Coming of age

Taniguchi, K. & Karin, M., 2018 May 1, In : Nature Reviews Immunology. 18, 5, p. 309-324 16 p.

Research output: Contribution to journalReview article

295 Citations (Scopus)

Observational evidence of the association between handgrip strength, hand dexterity, and cognitive performance in community-dwelling older adults: A systematic review

Kobayashi-Cuya, K. E., Sakurai, R., Suzuki, H., Ogawa, S., Takebayashi, T. & Fujiwara, Y., 2018 Jan 1, In : Journal of epidemiology. 28, 9, p. 373-381 9 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Pivotal role of innate myeloid cells in cerebral post-ischemic sterile inflammation

Tsuyama, J., Nakamura, A., Ooboshi, H., Yoshimura, A. & Shichita, T., 2018 Nov 1, In : Seminars in Immunopathology. 40, 6, p. 523-538 16 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Rab family small GTPases-mediated regulation of intracellular logistics in neural development

Shikanai, M., Yuzaki, M. & Kawauchi, T., 2018 Aug 1, In : Histology and Histopathology. 33, 8, p. 765-771 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Temporal trends in renal function and birthweight in Japanese adolescent males (1998-2015)

Kanda, T., Takeda, A., Hirose, H., Abe, T., Urai, H., Inokuchi, M., Wakino, S., Tokumura, M., Itoh, H. & Kawabe, H., 2018 Feb 1, In : Nephrology Dialysis Transplantation. 33, 2, p. 304-310 7 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

The mechanism underlying the resolution of sterile inflammation through scavenger receptor

Shchita, T. & Yoshimura, A., 2018 Jan 1, In : Seikagaku. 90, 1, p. 99-102 4 p.

Research output: Contribution to journalReview article

The updated network meta-analysis of neoadjuvant therapy for HER2-positive breast cancer

Nakashoji, A., Hayashida, T., Yokoe, T., Maeda, H., Toyota, T., Kikuchi, M., Watanuki, R., Nagayama, A., Seki, T., Takahashi, M., Abe, T. & Kitagawa, Y., 2018 Jan 1, In : Cancer Treatment Reviews. 62, p. 9-17 9 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Two Classes of Secreted Synaptic Organizers in the Central Nervous System

Yuzaki, M., 2018 Feb 10, In : Annual Review of Physiology. 80, p. 243-262 20 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2017

Aberrant chromatin remodeling in gynecological cancer (Review)

Okawa, R., Banno, K., Iida, M., Yanokura, M., Takeda, T., Iijima, M., Irie, H. K., Nakamura, K., Adachi, M., Umene, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. & Aoki, D., 2017 Nov 1, In : Oncology Letters. 14, 5, p. 5107-5113 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
19 Citations (Scopus)

Genome-wide analysis of gynecologic cancer: The cancer genome atlas in ovarian and endometrial cancer (Review)

Iijima, M., Banno, K., Okawa, R., Yanokura, M., Iida, M., Takeda, T., Kunitomi-Irie, H., Adachi, M., Nakamura, K., Umene, K., Nogami, Y., Masuda, K., Tominaga, E. & Aoki, D., 2017 Mar 1, In : Oncology Letters. 13, 3, p. 1063-1070 8 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Identification of a novel CO-sensor protein PGRMCl that contributes to cancer proliferation

Kabe, Y. & Suematsu, M., 2017 Jan 1, In : Seikagaku. 89, 6, p. 889-893 5 p.

Research output: Contribution to journalReview article

Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism

Nishimoto, K., Koga, M., Seki, T., Oki, K., Gomez-Sanchez, E. P., Gomez-Sanchez, C. E., Naruse, M., Sakaguchi, T., Morita, S., Kosaka, T., Oya, M., Ogishima, T., Yasuda, M., Suematsu, M., Kabe, Y., Omura, M., Nishikawa, T. & Mukai, K., 2017 Feb 5, In : Molecular and Cellular Endocrinology. 441, p. 124-133 10 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications

Iizuka-Koga, M., Nakatsukasa, H., Ito, M., Akanuma, T., Lu, Q. & Yoshimura, A., 2017 Sep 1, In : Journal of Autoimmunity. 83, p. 113-121 9 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Isolation of dental pulp stem cells with high osteogenic potential

Yasui, T., Mabuchi, Y., Morikawa, S., Onizawa, K., Akazawa, C., Nakagawa, T., Okano, H. & Matsuzaki, Y., 2017 Apr 10, In : Inflammation and Regeneration. 37, 1, p. 1-10 10 p.

Research output: Contribution to journalReview article

Open Access
11 Citations (Scopus)

New use of microsatellite instability analysis in endometrial cancer (Review)

Kunitomi, H., Banno, K., Yanokura, M., Takeda, T., Iijima, M., Nakamura, K., Iida, M., Adachi, M., Watanabe, K., Matoba, Y., Kobayashi, Y., Tominaga, E. & Aoki, D., 2017, In : Oncology Letters. 14, 3, p. 3297-3301 5 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Optimal plateau pressure for patients with acute respiratory distress syndrome: A protocol for a systematic review and meta-analysis with meta-regression

Yasuda, H., Nishimura, T., Kamo, T., Sanui, M., Nango, E., Abe, T., Takebayashi, T., Lefor, A. K. & Hashimoto, S., 2017 May 1, In : BMJ open. 7, 5, e015091.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Placebo effects in the treatment of Noncognitive symptoms of Alzheimer’s disease: Analysis of the CATIE-AD data

Ozawa, C., Roberts, R., Yoshida, K., Suzuki, T., Lebowitz, B., Reeves, S., Howard, R., Abe, T., Mimura, M. & Uchida, H., 2017 Nov 1, In : Journal of Clinical Psychiatry. 78, 9, p. e1204-e1210

Research output: Contribution to journalReview article

6 Citations (Scopus)

Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy

Chikuma, S., Kanamori, M., Mise-Omata, S. & Yoshimura, A., 2017 Apr 1, In : Cancer Science. 108, 4, p. 574-580 7 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

Synapse organization and modulation via C1q family proteins and their receptors in the central nervous system

Matsuda, K., 2017 Mar 1, In : Neuroscience Research. 116, p. 46-53 8 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

The C1q complement family of synaptic organizers: not just complementary

Yuzaki, M., 2017 Aug 1, In : Current Opinion in Neurobiology. 45, p. 9-15 7 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)