Research Output 1978 2019

2005
62 Citations (Scopus)

Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor

Nagai, N., Noda, K., Urano, T., Kubota, Y., Shinoda, H., Koto, T., Shinoda, K., Inoue, M., Shiomi, T., Ikeda, E., Tsubota, K., Suda, T., Oike, Y. & Ishida, S., 2005 Mar, In : Investigative Ophthalmology and Visual Science. 46, 3, p. 1078-1084 7 p.

Research output: Contribution to journalArticle

Physiologic Neovascularization
Retinal Neovascularization
Angiotensin Type 1 Receptor
Retinal Vessels
Vascular Endothelial Growth Factor Receptor-1

Skin reconstitution in SCID mice

Kishi, K., Kubota, Y., Katsube, K., Satoh, H., Shimizu, Y., Imanishi, N., Nakajima, H. & Nahajima, T., 2005 Sep, In : Japanese Journal of Plastic and Reconstructive Surgery. 48, 9, p. 979-984 6 p.

Research output: Contribution to journalArticle

SCID Mice
Skin
Cicatrix
Cell Transplantation
Wounds and Injuries
67 Citations (Scopus)

Suppression of ocular inflammation in endotoxin-induced uveitis by blocking the angiotensin II type 1 receptor

Nagai, N., Oike, Y., Noda, K., Urano, T., Kubota, Y., Ozawa, Y., Shinoda, H., Koto, T., Shinoda, K., Inoue, M., Tsubota, K., Yamashiro, K., Suda, T. & Ishida, S., 2005, In : Investigative Ophthalmology and Visual Science. 46, 8, p. 2925-2931 7 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Uveitis
Endotoxins
Inflammation
Intercellular Adhesion Molecule-1
9 Citations (Scopus)

Switching of α-catenin from αE-catenin in the cortical ventricular zone to αN-catenin II in the intermediate zone

Ajioka, I. & Nakajima, K., 2005 Nov 7, In : Developmental Brain Research. 160, 1, p. 106-111 6 p.

Research output: Contribution to journalArticle

Catenins
Telencephalon
Cadherins
111 Citations (Scopus)
Interneurons
Prosencephalon
Telencephalon
Hippocampus
Time-Lapse Imaging
10 Citations (Scopus)

The fetal dermal but not loose fascial mesenchymal cells possess regenerative activity of dermal structure

Kishi, K., Katsube, K., Satoh, H., Imanishi, N., Nakajima, H. & Nakajima, T., 2005, In : Cell Transplantation. 14, 9, p. 709-714 6 p.

Research output: Contribution to journalArticle

Skin
Cells
Defects
Fetal Movement
Fascia
3 Citations (Scopus)

The role of pit-1 in the regulation of the rat growth hormone-releasing hormone receptor transcription by glucocorticoids

Nogami, H., Hiraoka, Y., Ogasawara, K., Aiso, S. & Hisano, S., 2005 Dec, In : Journal of Molecular Endocrinology. 35, 3, p. 477-488 12 p.

Research output: Contribution to journalArticle

Glucocorticoids
Transcription Factor Pit-1
Transcriptional Silencer Elements
Response Elements
Genes
2 Citations (Scopus)

The transmembrane protein, Tincar, is involved in the development of the compound eye in Drosophila melanogaster

Hirota, Y., Sawamoto, K., Takahashi, K., Ueda, R. & Okano, H., 2005 Feb, In : Development Genes and Evolution. 215, 2, p. 90-96 7 p.

Research output: Contribution to journalArticle

transmembrane proteins
compound eyes
Drosophila melanogaster
eyes
peripheral nervous system
40 Citations (Scopus)

Transforming growth factor β2 is a neuronal death-inducing ligand for amyloid-β precursor protein

Hashimoto, Y., Chiba, T., Yamada, M., Nawa, M., Kanekura, K., Suzuki, H., Terashita, K., Aiso, S., Nishimoto, I. & Matsuoka, M., 2005 Nov, In : Molecular and Cellular Biology. 25, 21, p. 9304-9317 14 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Transforming Growth Factors
Ligands
Alzheimer Disease
Gi-Go GTP-Binding Protein alpha Subunits
2004
22 Citations (Scopus)

Amino- and Carboxyl-Terminal Mutants of Presenilin 1 Cause Neuronal Cell Death Through Distinct Toxic Mechanisms: Study of 27 Different Presenilin 1 Mutants

Hashimoto, Y., Tsukamoto, E., Niikura, T., Yamagishi, Y., Ishizaka, M., Aiso, S., Takashima, A. & Nishimoto, I., 2004 Feb 1, In : Journal of Neuroscience Research. 75, 3, p. 417-428 12 p.

Research output: Contribution to journalArticle

Presenilin-1
Poisons
Alzheimer Disease
Cell Death
NADPH Oxidase
31 Citations (Scopus)
Lubricants
Subcutaneous Tissue
Cadaver
24 Citations (Scopus)

Arterial anatomy of the lower lip

Kawai, K., Imanishi, N., Nakajima, H., Aiso, S., Kakibuchi, M. & Hosokawa, K., 2004, In : Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery. 38, 3, p. 135-139 5 p.

Research output: Contribution to journalArticle

Lip
Anatomy
Arteries
Muscles
Subcutaneous Tissue
38 Citations (Scopus)
GABAergic Neurons
Visual Cortex
Parturition
Neurons
Interneurons
39 Citations (Scopus)

CCL22 and CCL17 in rat radiation pneumonitis and in human idiopathic pulmonary fibrosis

Inoue, T., Fujishima, S., Ikeda, E., Yoshie, O., Tsukamoto, N., Aiso, S., Aikawa, N., Kubo, A., Matsushima, K. & Yamaguchi, K., 2004 Jul, In : European Respiratory Journal. 24, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

Radiation Pneumonitis
Idiopathic Pulmonary Fibrosis
Chemokines
Pulmonary Fibrosis
CCR4 Receptors
41 Citations (Scopus)

Characterization of V642I-AβPP-induced cytotoxicity in primary neurons

Niikura, T., Yamada, M., Chiba, T., Aiso, S., Matsuoka, M. & Nishimoto, I., 2004 Jul 1, In : Journal of Neuroscience Research. 77, 1, p. 54-62 9 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Neurons
Alzheimer Disease
Amyloid
Protein Multimerization
20 Citations (Scopus)

Components of the Reelin Signaling Pathway Are Expressed in the Spinal Cord

Yip, Y. P., Capriotti, C., Magdaleno, S., Benhayon, D., Curran, T., Nakajima, K. & Yip, J. W., 2004 Mar 1, In : Journal of Comparative Neurology. 470, 2, p. 210-219 10 p.

Research output: Contribution to journalArticle

Spinal Cord
Neurons
Brain
Lipoprotein Receptors
Messenger RNA
11 Citations (Scopus)

Cytotoxic mechanisms by M239V presenilin 2, a little-analyzed Alzheimer's disease-causative mutant

Abe, Y., Hashimoto, Y., Tomita, Y., Terashita, K., Aiso, S., Tajima, H., Niikura, T., Matsuoka, M. & Nishimoto, I., 2004 Aug 15, In : Journal of Neuroscience Research. 77, 4, p. 583-595 13 p.

Research output: Contribution to journalArticle

Presenilin-2
Alzheimer Disease
Oxypurinol
Caspase Inhibitors
Xanthine Oxidase
33 Citations (Scopus)

Humanin: After the discovery

Niikura, T., Chiba, T., Aiso, S., Matsuoka, M. & Nishimoto, I., 2004 Dec, In : Molecular Neurobiology. 30, 3, p. 327-340 14 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Cell Death
humanin
Peptides
JNK Mitogen-Activated Protein Kinases
16 Citations (Scopus)

Humanin antagonists: Mutants that interfere with dimerization inhibit neuroprotection by Humanin

Hashimoto, Y., Terashita, K., Niikura, T., Yamagishi, Y., Ishizaka, M., Kanekura, K., Chiba, T., Yamada, M., Kita, Y., Aiso, S., Matsuoka, M. & Nishimoto, I., 2004 May, In : European Journal of Neuroscience. 19, 9, p. 2357-2364 8 p.

Research output: Contribution to journalArticle

Dimerization
humanin
Neuroprotection
Peptides
Insertional Mutagenesis
53 Citations (Scopus)

Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-β peptides via p75NTR/PLAIDD

Hashimoto, Y., Kaneko, Y., Tsukamoto, E., Frankowski, H., Koyama, K., Kita, Y., Niikura, T., Aiso, S., Bredesen, D. E., Matsuoka, M. & Nishimoto, I., 2004 Aug, In : Journal of Neurochemistry. 90, 3, p. 549-558 10 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptor
Cell death
Amyloid
Cell Death
Apoptosis
39 Citations (Scopus)

Neuroprotective effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo

Chiba, T., Hashimoto, Y., Tajima, H., Yamada, M., Kato, R., Niikura, T., Terashita, K., Schulman, H., Aiso, S., Kita, Y., Matsuoka, M. & Nishimoto, I., 2004 Nov 15, In : Journal of Neuroscience Research. 78, 4, p. 542-552 11 p.

Research output: Contribution to journalArticle

Neuroprotective Agents
Amyotrophic Lateral Sclerosis
Alzheimer Disease
Cell Death
Motor Neuron Disease
37 Citations (Scopus)

Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice

Kawasumi, M., Chiba, T., Yamada, M., Miyamae-Kaneko, M., Matsuoka, M., Nakahara, J., Tomita, T., Iwatsubo, T., Kato, S., Aiso, S., Nishimoto, I. & Koyama, K., 2004 May, In : European Journal of Neuroscience. 19, 10, p. 2826-2838 13 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Mutation
Genes
Short-Term Memory
5 Citations (Scopus)

The Gtx Homeodomain Transcription Factor Exerts Neuroprotection Using Its Homeodomain

Hashimoto, Y., Tsuji, O., Kanekura, K., Aiso, S., Niikura, T., Matsuoka, M. & Nishimoto, I., 2004 Apr 16, In : Journal of Biological Chemistry. 279, 16, p. 16767-16777 11 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Transcription Factors
Genes
Cell death
Alzheimer Disease
438 Citations (Scopus)

The Wnt/β-catenin pathway directs neuronal differentation of cortical neural precursor cells

Hirabayashi, Y., Itoh, Y., Tabata, H., Nakajima, K., Akiyama, T., Masuyama, N. & Gotoh, Y., 2004 Jun, In : Development. 131, 12, p. 2791-2801 11 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Neocortex
Cell Size
Neuroglia

Tissue engineering of skeletal muscle in collagen gel

Kishi, K., Satoh, H., Tanaka, T., Kubota, Y., Koyama, T., Imanishi, N., Nakajima, H. & Nakajima, T., 2004 Sep, In : Japanese Journal of Plastic and Reconstructive Surgery. 47, 9, p. 1001-1005 5 p.

Research output: Contribution to journalArticle

Tissue Engineering
Skeletal Muscle
Collagen
Gels
Muscle Cells
77 Citations (Scopus)

Transplanted mesenchymal stem cells are effective for skin regeneration in acute cutaneous wounds

Satoh, H., Kishi, K., Tanaka, T., Kubota, Y., Nakajima, T., Akasaka, Y. & Ishii, T., 2004, In : Cell Transplantation. 13, 4, p. 405-412 8 p.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Regeneration
Skin
Plastics
2003
29 Citations (Scopus)

Anatomical relationship between arteries and veins in the paraumbilical region

Imanishi, N., Nakajima, H., Minabe, T., Chang, H. & Aiso, S., 2003, In : British Journal of Plastic Surgery. 56, 6, p. 552-556 5 p.

Research output: Contribution to journalArticle

Veins
Arteries
Skin
Femoral Vein
Subcutaneous Tissue
2 Citations (Scopus)

A novel Xenopus laevis SRY-related gene, xSox33

Hagiuda, J., Hiraoka, Y., Hasegawa, M., Ogawa, M. & Aiso, S., 2003 Jul 28, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1628, 2, p. 140-145 6 p.

Research output: Contribution to journalArticle

sry Genes
Xenopus laevis
Anura
Reverse Transcription
Genes
81 Citations (Scopus)

A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults

Niikura, T., Hashimoto, Y., Tajima, H., Ishizaka, M., Yamagishi, Y., Kawasumi, M., Nawa, M., Terashita, K., Also, S. & Nishimoto, I., 2003 Mar, In : European Journal of Neuroscience. 17, 6, p. 1150-1158 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Peptides
RING Finger Domains
Tripartite Motif Proteins
humanin
18 Citations (Scopus)

Cell and molecular mechanisms that control cortical layer formation in the brain

Kubo, K. & Nakajima, K., 2003 Mar, In : Keio Journal of Medicine. 52, 1, p. 8-20 13 p.

Research output: Contribution to journalArticle

Brain
Cerebral Cortex
Genes
Central Nervous System
Neurons
14 Citations (Scopus)

Cellular and molecular mechanisms of neuronal migration in neocortical development

Honda, T., Tabata, H. & Nakajima, K., 2003 Jun, In : Seminars in Cell and Developmental Biology. 14, 3, p. 169-174 6 p.

Research output: Contribution to journalArticle

Cerebral Cortex
Observation
Neurons
Brain

Characteristics of trochanteric pressure sore and its surgical treatments

Nakajima, H., Imanishi, N. & Fukuzumi, S., 2003 Jun 1, In : Japanese Journal of Plastic and Reconstructive Surgery. 46, 6, p. 577-586 10 p.

Research output: Contribution to journalArticle

Pressure Ulcer
Myocutaneous Flap
Ulcer
Fascia Lata
Bursitis
74 Citations (Scopus)

Characterization of the toxic mechanism triggered by Alzheimer's amyloid-β peptides via p75 neurotrophin receptor in neuronal hybrid cells

Tsukamoto, E., Hashimoto, Y., Kanekura, K., Niikura, T., Aiso, S. & Nishimoto, I., 2003 Sep 1, In : Journal of Neuroscience Research. 73, 5, p. 627-636 10 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptor
Hybrid Cells
Poisons
Pertussis Toxin
Amyloid
Drosophila
Gene Expression
Proteins

Erratum: The Polycomb-group protein ENX-2 interacts with ZAP-70 (Immunology Letters (2003) 86 (57-61) PII: S0165247802002936)

Ogawa, M., Hiraoka, Y. & Aiso, S., 2003 Oct 9, In : Immunology Letters. 89, 1, p. 89 1 p.

Research output: Contribution to journalArticle

Polycomb-Group Proteins
Allergy and Immunology
18 Citations (Scopus)

Expression of Fc receptor for immunoglobulin M in oligodendrocytes and myelin of mouse central nervous system

Nakahara, J., Seiwa, C., Shibuya, A., Aiso, S. & Asou, H., 2003 Feb 6, In : Neuroscience Letters. 337, 2, p. 73-76 4 p.

Research output: Contribution to journalArticle

Immunoglobulin Fc Fragments
Fc Receptors
Oligodendroglia
Myelin Sheath
Immunoglobulin M
9 Citations (Scopus)

Immunomolecular mapping of adherens junction and desmosomal components in normal human epidermis

Ishiko, A., Matsunaga, Y., Masunaga, T., Aiso, S., Nishikawa, T. & Shimizu, H., 2003 Dec, In : Experimental Dermatology. 12, 6, p. 747-754 8 p.

Research output: Contribution to journalArticle

Adherens Junctions
Epidermis
Desmosomes
Cell membranes
Electron microscopy
80 Citations (Scopus)

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death

Hashimoto, Y., Tsuji, O., Niikura, T., Yamagishi, Y., Ishizaka, M., Kawasumi, M., Chiba, T., Kanekura, K., Yamada, M., Tsukamoto, E., Koyama, K., Terashita, K., Aiso, S., Lint, A. & Nishimoto, I., 2003 Feb, In : Journal of Neurochemistry. 84, 4, p. 864-877 14 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Amyloid beta-Protein Precursor
Cell death
Cell Death
Pertussis Toxin
355 Citations (Scopus)

Multipolar Migration: The Third Mode of Radial Neuronal Migration in the Developing Cerebral Cortex

Tabata, H. & Nakajima, K., 2003 Nov 5, In : Journal of Neuroscience. 23, 31, p. 9996-10001 6 p.

Research output: Contribution to journalArticle

Cerebral Cortex
Locomotion
Cell Movement
Cell Polarity
Lateral Ventricles

Nasal reconstruction by thin forearm flap

Nakajima, H., Imanishi, N., Kishi, K. & Sasaki, K., 2003 Sep 1, In : Japanese Journal of Plastic and Reconstructive Surgery. 46, 9, p. 891-900 10 p.

Research output: Contribution to journalArticle

Nose
Forearm
Bone and Bones
Skin
Veins
7 Citations (Scopus)

Nuclear translocation of Xenopus laevis paxillin

Ogawa, M., Hiraoka, Y. & Aiso, S., 2003 May 16, In : Biochemical and Biophysical Research Communications. 304, 4, p. 676-683 8 p.

Research output: Contribution to journalArticle

Paxillin
Xenopus laevis
Anura
Tyrosine
Phosphorylation
19 Citations (Scopus)

Prior burn insult induces lethal acute lung injury in endotoxemic mice: Effects of cytokine inhibition

Sasaki, J., Fujishima, S., Iwamura, H., Wakitani, K., Aiso, S. & Aikawa, N., 2003 Feb 1, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 284, 2 28-2

Research output: Contribution to journalArticle

Acute Lung Injury
Cytokines
Endotoxemia
Burns
Mortality
17 Citations (Scopus)

Role of radial fibers in controlling the onset of myelination

Nakahara, J., Takemura, M., Gomi, H., Tsunematsu, K. I., Itohara, S., Asou, H., Ogawa, M., Aiso, S. & Tan-Takeuchi, K., 2003 May 1, In : Journal of Neuroscience Research. 72, 3, p. 279-289 11 p.

Research output: Contribution to journalArticle

Glial Fibrillary Acidic Protein
Astrocytes
Axons
Oligodendroglia
Lateral Ventricles
67 Citations (Scopus)

Segregation and coactivation of developing neocortical layer 1 neurons

Soda, T., Nakashima, R., Watanabe, D., Nakajima, K., Pastan, I. & Nakanishi, S., 2003 Jul 16, In : Journal of Neuroscience. 23, 15, p. 6272-6279 8 p.

Research output: Contribution to journalArticle

Neurons
Green Fluorescent Proteins
GABA-A Receptors
Cerebral Cortex
gamma-Aminobutyric Acid
51 Citations (Scopus)

Signaling via immunoglobulin Fc receptors induces oligodendrocyte precursor cell differentiation

Nakahara, J., Tan-Takeuchi, K., Seiwa, C., Gotoh, M., Kaifu, T., Ujike, A., Inui, M., Yagi, T., Ogawa, M., Aiso, S., Takai, T. & Asou, H., 2003 Jun 1, In : Developmental Cell. 4, 6, p. 841-852 12 p.

Research output: Contribution to journalArticle

Fc Receptors
Oligodendroglia
Myelin Basic Protein
Immunoglobulins
Cell Differentiation
10 Citations (Scopus)

The Polycomb-group protein ENX-2 interacts with ZAP-70

Ogawa, M., Hiraoka, Y. & Aiso, S., 2003 Mar 3, In : Immunology Letters. 86, 1, p. 57-61 5 p.

Research output: Contribution to journalArticle

Polycomb-Group Proteins
Tyrosine
Protein-Tyrosine Kinases
Proteins
Jurkat Cells
27 Citations (Scopus)

Transplanted endothelial progenitor cells augment the survival areas of rat dorsal flaps

Kubota, Y., Kishi, K., Satoh, H., Tanaka, T., Nakajima, H. & Nakajima, T., 2003, In : Cell Transplantation. 12, 6, p. 647-657 11 p.

Research output: Contribution to journalArticle

Endothelial cells
Rats
Cell Survival
Endothelial Cells
Flaps
2002

A challenge to construct functional tissue engineered skeletal muscle

Kishi, K., Satoh, H., Tanaka, T., Kubota, Y., Imanishi, N., Nakajima, H. & Nakajima, T., 2002, In : Japanese Journal of Plastic and Reconstructive Surgery. 45, 5, p. 419-424 6 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Tissue Engineering
Muscles
Neuromuscular Junction
Microcirculation
21 Citations (Scopus)

A composite hormone response element regulates transcription of the rat GHRH receptor gene

Nogami, H., Hiraoka, Y., Matsubara, M., Nonobe, E., Harigaya, T., Katayama, M., Hemmi, N., Kobayashi, S., Mogi, K., Aiso, S., Kawamura, K. & Hisano, S., 2002, In : Endocrinology. 143, 4, p. 1318-1326 9 p.

Research output: Contribution to journalArticle

Response Elements
Hormones
Sequence Deletion
Genes
Glucocorticoids
104 Citations (Scopus)

Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults

Tajima, H., Niikura, T., Hashimoto, Y., Ito, Y., Kita, Y., Terashita, K., Yamazaki, K., Koto, A., Aiso, S. & Nishimoto, I., 2002 May 24, In : Neuroscience Letters. 324, 3, p. 227-231 5 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Peptides
Open Reading Frames
Brain
Testis