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(+)-Rhododendrol and epi-rhododendrin suppress the no production by activated macrophages in vivo

Fushiya, S., Kabe, Y., Ikegaya, Y. & Takano, F., 1998 Nov 2, In : Planta Medica. 64, 7, p. 598-602 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

5-Lipoxygenase inhibitor (AA-861) attenuates neutrophil-mediated oxidative stress on the venular endothelium in endotoxemia

Suematsu, M., Miura, S., Suzuki, M., Nagata, H., Morishita, T., Oshio, C. & Tsuchiya, M., 1988 Jan 1, In : Journal of Clinical and Laboratory Immunology. 25, 1, p. 41-45 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abnormal phospholipids distribution in the prefrontal cortex from a patient with schizophrenia revealed by matrix-assisted laser desorption/ionization imaging mass spectrometry

Matsumoto, J., Sugiura, Y., Yuki, D., Hayasaka, T., Goto-Inoue, N., Zaima, N., Kunii, Y., Wada, A., Yang, Q., Nishiura, K., Akatsu, H., Hori, A., Hashizume, Y., Yamamoto, T., Ikemoto, K., Setou, M. & Niwa, S. I., 2011 Jun 1, In : Analytical and bioanalytical chemistry. 400, 7, p. 1933-1943 11 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

A case of Crohn's colitis with cecal perforation and abnormalities of coagulofibrinolytic system

Tsuzuki, Y., Serizawa, H., Miura, S., Kurose, I., Suematsu, M., Hibi, T., Ishii, H., Tashiro, Y., Kodaira, S. & Tsuchiya, M., 1990 Jan 1, In : Nippon Shokakibyo Gakkai Zasshi. 87, 9, p. 1878-1882 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Acid suppression by proton pump inhibitors enhances aquaporin-4 and KCNQ1 expression in gastric fundic parietal cells in mouse

Matsuzaki, J., Suzuki, H., Minegishi, Y., Sugai, E., Tsugawa, H., Yasui, M. & Hibi, T., 2010 Dec 1, In : Digestive Diseases and Sciences. 55, 12, p. 3339-3348 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Activated leukocytes and endothelial cells enhance retention of ultrasound contrast microspheres containing perfluoropropane in inflamed venules

Yasu, T., Greener, Y., Jablonski, E., Killam, A. L., Fukuda, S., Suematsu, M., Tojo, S. J. & Schmid-Schönbein, G. W., 2005 Feb 15, In : International Journal of Cardiology. 98, 2, p. 245-252 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Activated platelets and endothelial cell interaction with neutrophils under flow conditions

Mine, S., Fujisaki, T., Suematsu, M. & Tanaka, Y., 2001 Jan 1, In : Internal Medicine. 40, 11, p. 1085-1092 8 p.

Research output: Contribution to journalArticle

Open Access
35 Citations (Scopus)

Acute gastric mucosal lesions induced by vasomotor derangement —Participation of xanthine oxidase and neutrophil-mediated oxidative stress—

Suzuki, M., Suematsu, M., Miura, S., Oda, M., Tsuchiya, M., Nagata, H. & Morishita, T., 1988 Jan 1, In : Nippon Shokakibyo Gakkai Zasshi. 85, 4, p. 835-842 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

Tanoue, T., Morita, S., Plichta, D. R., Skelly, A. N., Suda, W., Sugiura, Y., Narushima, S., Vlamakis, H., Motoo, I., Sugita, K., Shiota, A., Takeshita, K., Yasuma-Mitobe, K., Riethmacher, D., Kaisho, T., Norman, J. M., Mucida, D., Suematsu, M., Yaguchi, T., Bucci, V. & 8 others, Inoue, T., Kawakami, Y., Olle, B., Roberts, B., Hattori, M., Xavier, R. J., Atarashi, K. & Honda, K., 2019 Jan 31, In : Nature. 565, 7741, p. 600-605 6 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Adenine nucleotide translocator transports haem precursors into mitochondria

Azuma, M., Kabe, Y., Kuramori, C., Kondo, M., Yamaguchi, Y. & Handa, H., 2008 Aug 27, In : PloS one. 3, 8, e3070.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions

Sugiura, Y., Takeo, E., Shimma, S., Yokota, M., Higashi, T., Seki, T., Mizuno, Y., Oya, M., Kosaka, T., Omura, M., Nishikawa, T., Suematsu, M. & Nishimoto, K., 2018 Dec 1, In : Hypertension (Dallas, Tex. : 1979). 72, 6, p. 1345-1354 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori

Tsugawa, H., Suzuki, H., Nakagawa, I., Nishizawa, T., Saito, Y., Suematsu, M. & Hibi, T., 2008 Nov 7, In : Biochemical and Biophysical Research Communications. 376, 1, p. 46-51 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Alteration of intestinal microcirculation during portal pressure elevation

Nagata, H., Sekizuka, E., Oshio, C., Suematsu, M., Miura, S., Houzawa, S., Morishita, T. & Tuschiya, M., 1989 Jan 1, In : Journal of Gastroenterology and Hepatology. 4, SUPPL. 1, p. 117-118 2 p.

Research output: Contribution to journalArticle

Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis

Takeshita, M., Kuno, A., Suzuki, K., Matsuda, A., Shimazaki, H., Nakagawa, T., Otomo, Y., Kabe, Y., Suematsu, M., Narimatsu, H. & Takeuchi, T., 2016 May 21, In : Arthritis Research and Therapy. 18, 1, 112.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Altered expression of heme oxygenase-1 in the livers of patients with portal hypertensive diseases

Makino, N., Suematsu, M., Sugiura, Y., Morikawa, H., Shiomi, S., Goda, N., Sano, T., Nimura, Y., Sugimachi, K. & Ishimura, Y., 2001 Jan 1, In : Hepatology. 33, 1, p. 32-42 11 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

Yae, T., Tsuchihashi, K., Ishimoto, T., Motohara, T., Yoshikawa, M., Yoshida, G. J., Wada, T., Masuko, T., Mogushi, K., Tanaka, H., Osawa, T., Kanki, Y., Minami, T., Aburatani, H., Ohmura, M., Kubo, A., Suematsu, M., Takahashi, K., Saya, H. & Nagano, O., 2012 Jul 6, In : Nature communications. 3, 883.

Research output: Contribution to journalArticle

191 Citations (Scopus)

A method for determination of aldosterone in adrenal tributary venous serum by derivatization using Girard P reagent isotopologues followed by LC/ESI-MS/MS

Higashi, T., Akaishi, M., Yokota, M., Suzuki, T., Ogawa, S., Sugiura, Y., Nishikawa, T., Nishimoto, K. & Suematsu, M., 2018 Aug 15, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1092, p. 106-113 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

An ELISA assay for heme oxygenase (HO-1)

Kitchin, K. T., Anderson, W. L. & Suematsu, M., 2001 Jan 1, In : Journal of Immunological Methods. 247, 1-2, p. 153-161 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity

Ando, K., Hirao, S., Kabe, Y., Ogura, Y., Sato, I., Yamaguchi, Y., Wada, T. & Handa, H., 2008 Aug 1, In : Nucleic acids research. 36, 13, p. 4327-4336 10 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)
14 Citations (Scopus)

Application of high-performance magnetic nanobeads to biological sensing devices

Kabe, Y., Sakamoto, S., Hatakeyama, M., Yamaguchi, Y., Suematsu, M., Itonaga, M. & Handa, H., 2019 Jan 1, (Accepted/In press) In : Analytical and Bioanalytical Chemistry.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Application of micro-reactor chip technique for millisecond quenching of deuterium incorporation into 70S ribosomal protein complex

Yamamoto, T., Shimizu, Y., Ueda, T., Shiro, Y. & Suematsu, M., 2011 Apr 30, In : International Journal of Mass Spectrometry. 302, 1-3, p. 132-138 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos

Oka, M., Hashimoto, K., Yamaguchi, Y., Saitoh, S. I., Sugiura, Y., Motoi, Y., Honda, K., Kikko, Y., Ohata, S., Suematsu, M., Miura, M., Miyake, K., Katada, T. & Kontani, K., 2017, In : Journal of Cell Science. 130, 20, p. 3568-3577 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Arundic acid (ONO-2506) inhibits secondary injury and improves motor function in rats with spinal cord injury

Hanada, M., Shinjo, R., Miyagi, M., Yasuda, T., Tsutsumi, K., Sugiura, Y., Imagama, S., Ishiguro, N. & Matsuyama, Y., 2014 Feb 15, In : Journal of the Neurological Sciences. 337, 1-2, p. 186-192 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A serum sweet-doughnut protein facilitates fibrosis evaluation and therapy assessment in patients with viral hepatitis

Kuno, A., Ikehara, Y., Tanaka, Y., Ito, K., Matsuda, A., Sekiya, S., Hige, S., Sakamoto, M., Kage, M., Mizokami, M. & Narimatsu, H., 2013 Jan 28, In : Scientific reports. 3, 1065.

Research output: Contribution to journalArticle

158 Citations (Scopus)

A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis

Hayakawa, T., Kawasaki, S., Hirayama, Y., Tsutsui, T., Sugiyama, E., Adachi, K., Kon, R., Suematsu, M. & Sugiura, Y., 2019 Dec 1, In : Scientific reports. 9, 1, 3559.

Research output: Contribution to journalArticle

Open Access

Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm

Hase, Y., Tatsuno, M., Nishi, T., Kataoka, K., Kabe, Y., Yamaguchi, Y., Ozawa, N., Natori, M., Handa, H. & Watanabe, H., 2008 Feb 1, In : Biochemical and Biophysical Research Communications. 366, 1, p. 66-72 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Attenuation of endotoxin-induced intestinal microcirculatory damage by eicosapentanoic acid

Miura, S., Imaeda, H., Shiozaki, H., Kurose, I., Fukumura, D., Tashiro, H., Serizawa, H., Suematsu, M., Sekizuka, E. & Tsuchiya, M., 1993 Jan 1, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 264, 5 27-5, p. G828-G834

Research output: Contribution to journalArticle

41 Citations (Scopus)

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Saito, T., Kuma, A., Sugiura, Y., Ichimura, Y., Obata, M., Kitamura, H., Okuda, S., Lee, H. C., Ikeda, K., Kanegae, Y., Saito, I., Auwerx, J., Motohashi, H., Suematsu, M., Soga, T., Yokomizo, T., Waguri, S., Mizushima, N. & Komatsu, M., 2019 Dec 1, In : Nature communications. 10, 1, 1567.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics

Yang, H. J., Sugiura, Y., Ikegami, K., Konishi, Y. & Setou, M., 2012 Feb 17, In : Journal of Biological Chemistry. 287, 8, p. 5290-5300 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition

Wu, R., Murali, R., Kabe, Y., French, S. W., Chiang, Y. M., Liu, S., Sher, L., Wang, C. C., Louie, S. & Tsukamoto, H., 2018 Nov 1, In : Hepatology. 68, 5, p. 1726-1740 15 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

BH3-only protein Bim is associated with the degree of Helicobacter pylori-induced gastritis and is localized to the mitochondria of inflammatory cells in the gastric mucosa

Akazawa, Y., Matsuda, K., Isomoto, H., Matsushima, K., Kido, Y., Urabe, S., Yamaghchi, N., Ohnita, K., Takeshima, F., Kondo, H., Tsugawa, H., Suzuki, H., Moss, J., Nakao, K. & Nakashima, M., 2015 Sep 1, In : International Journal of Medical Microbiology. 305, 6, p. 553-562 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bile acid‐induced depolarization of mitochondrial membrane potential preceding cell injury in cultured gastric mucosal cells

MIURA, SOICHIRO., FUKUMURA, DAI., SHIOZAKI, HIROSHI., SUZUKI, MASAYUKI., KUROSE, IWAO., SUEMATSU, MAKOTO., TSUCHIYA, MASAHARU. & ISHII, HIROMASA., 1995 Dec, In : Journal of Gastroenterology and Hepatology. 10, 6, p. 621-626 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bile acids increase levels of microRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis

Matsuzaki, J., Suzuki, H., Tsugawa, H., Watanabe, M., Hossain, S., Arai, E., Saito, Y., Sekine, S., Akaike, T., Kanai, Y., Mukaisho, K. I., Auwerx, J. & Hibi, T., 2013 Dec, In : Gastroenterology. 145, 6, p. 1300-1311 12 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Bilirubin Production and Hemeoxygenase-1 Expression in Ischemia-Reperfused Rat Liver in vivo

Kobayashi, T., Sato, Y., Yamamoto, S., Takeishi, T., Hirano, K. I., Watanabe, T., Kurosaki, I., Shirai, Y., Naito, M., Suematsu, M. & Hatakeyama, K., 2003 Dec 1, In : Japanese Pharmacology and Therapeutics. 31, SUPPL. 1, p. S109-S117+S131

Research output: Contribution to journalArticle

Bilirubin rinse: A simple protectant against the rat liver graft injury mimicking heme oxygenase-1 preconditioning

Kato, Y., Shimazu, M., Kondo, M., Uchida, K., Kumamoto, Y., Wakabayashi, G., Kitajima, M. & Suematsu, M., 2003 Aug 1, In : Hepatology. 38, 2, p. 364-373 10 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Binding profiles and cytokine-inducing effects of fish rhamnose-binding lectins on Burkitt's lymphoma Raji cells

Hosono, M., Sugawara, S., Matsuda, A., Tatsuta, T., Koide, Y., Hasan, I., Ozeki, Y. & Nitta, K., 2014 Oct, In : Fish Physiology and Biochemistry. 40, 5, p. 1559-1572 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica

Nurkanto, A., Jeelani, G., Yamamoto, T., Hishiki, T., Naito, Y., Suematsu, M., Hashimoto, T. & Nozaki, T., 2018 Nov 30, In : Frontiers in Microbiology. 9, NOV, 2902.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cadmium exposure alters metabolomics of sulfur-containing amino acids in rat testes

Sugiura, Y., Kashiba, M., Maruyama, K., Hoshikawa, K., Sasaki, R., Saito, K., Kimura, H., Goda, N. & Suematsu, M., 2005 May 1, In : Antioxidants and Redox Signaling. 7, 5-6, p. 781-787 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells

Tsugawa, H., Kato, C., Mori, H., Matsuzaki, J., Kameyama, K., Saya, H., Hatakeyama, M., Suematsu, M. & Suzuki, H., 2019 Jan 1, In : CMGH. 8, 3, p. 319-334 16 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

Kuramori, C., Azuma, M., Kume, K., Kaneko, Y., Inoue, A., Yamaguchi, Y., Kabe, Y., Hosoya, T., Kizaki, M., Suematsu, M. & Handa, H., 2009 Feb 6, In : Biochemical and Biophysical Research Communications. 379, 2, p. 519-525 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy

Tsugawa, H., Mori, H., Matsuzaki, J., Sato, A., Saito, Y., Imoto, M., Suematsu, M. & Suzuki, H., 2018 Jan 1, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver

Suematsu, M., Goda, N., Sano, T., Kashiwagi, S., Egawa, T., Shinoda, Y. & Ishimura, Y., 1995 Nov, In : Journal of Clinical Investigation. 96, 5, p. 2431-2437 7 p.

Research output: Contribution to journalArticle

Open Access
344 Citations (Scopus)

Carbon monoxide as a guardian against hepatobiliary dysfunction

Suematsu, M., Tsukada, K., Tajima, T., Yamamoto, T., Ochiai, D., Watanabe, H., Yoshimura, Y. & Goda, N., 2005 Nov 1, In : Alcoholism: Clinical and Experimental Research. 29, 11 SUPPL., p. 134S-139S

Research output: Contribution to journalArticle

6 Citations (Scopus)

Carbon monoxide as an endogenous modulator of hepatic vascular perfusion

Suematsu, M., Kashiwagi, S., Sano, T., Goda, N., Shinoda, Y. & Ishimura, Y., 1994 Dec 15, In : Biochemical and Biophysical Research Communications. 205, 2, p. 1333-1337 5 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Carbon monoxide as a regulator of bile canalicular contractility in cultured rat hepatocytes

Shinoda, Y., Suematsu, M., Wakabayashi, Y., Suzuki, T., Goda, N., Saito, S., Yamaguchi, T. & Ishimura, Y., 1998 Aug 17, In : Hepatology. 28, 2, p. 286-295 10 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver

Kyokane, T., Norimizu, S., Taniai, H., Yamaguchi, T., Takeoka, S., Tsuchida, E., Naito, M., Nimura, Y., Ishimura, Y. & Suematsu, M., 2001 Jan 1, In : Gastroenterology. 120, 5, p. 1227-1240 14 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)

Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver

Wakabayashi, Y., Takamiya, R., Mizuki, A., Kyokane, T., Goda, N., Yamaguchi, T., Takeoka, S., Tsuchida, E., Suematsu, M. & Ishimura, Y., 1999 Nov 1, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 277, 5 40-5, p. G1088-G1096

Research output: Contribution to journalArticle

62 Citations (Scopus)

Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase

Yamamoto, T., Takano, N., Ishiwata, K. & Suematsu, M., 2011 Jan 1, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 96-100 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

CD44 variant 9 expression in primary early gastric cancer as a predictive marker for recurrence

Hirata, K., Suzuki, H., Imaeda, H., Matsuzaki, J., Tsugawa, H., Nagano, O., Asakura, K., Saya, H. & Hibi, T., 2013 Jul 23, In : British Journal of Cancer. 109, 2, p. 379-386 8 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)