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2020

Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas

Tian, Y., Arai, E., Makiuchi, S., Tsuda, N., Kuramoto, J., Ohara, K., Takahashi, Y., Ito, N., Ojima, H., Hiraoka, N., Gotoh, M., Yoshida, T. & Kanai, Y., 2020, (Accepted/In press) In : Journal of Cancer Research and Clinical Oncology.

Research output: Contribution to journalArticle

Open Access

A case of intrahepatic cholangiocellular carcinoma due to thorotrast deposition, well-controlled by radiofrequency ablation therapy

Taniki, N., Nakamoto, N., Yoshida, A., Chu, P. S., Ikura, A., Yamataka, K., Morikawa, R., Shiba, S., Yamaguchi, A., Usui, S., Ojiro, K., Ebinuma, H., Saito, H., Kubota, N., Masugi, Y., Sakamto, M. & Kanai, T., 2020, In : Acta Hepatologica Japonica. 61, 5, p. 262-269 8 p.

Research output: Contribution to journalArticle

Open Access

A case of pancreatic hamartoma with characteristic radiological findings: radiological-pathological correlation

Toyama, K., Matsusaka, Y., Okuda, S., Miura, E., Kubota, N., Masugi, Y., Kitago, M., Hori, S., Yokose, T., Shinoda, M., Sakamoto, M. & Jinzaki, M., 2020 Jul 1, In : Abdominal Radiology. 45, 7, p. 2244-2248 5 p.

Research output: Contribution to journalArticle

Activation of extracellular signal-regulated kinase is associated with hepatocellular carcinoma with aggressive phenotypes

Minagawa, T., Yamazaki, K., Masugi, Y., Tsujikawa, H., Ojima, H., Hibi, T., Abe, Y., Yagi, H., Kitago, M., Shinoda, M., Itano, O., Kitagawa, Y. & Sakamoto, M., 2020 Mar 1, In : Hepatology Research. 50, 3, p. 353-364 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ADAM10 is indispensable for longitudinal bone growth in mice

Mizuno, S., Yoda, M., Kimura, T., Shimoda, M., Akiyama, H., Chiba, K., Nakamura, M. & Horiuchi, K., 2020 May, In : Bone. 134, 115273.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Hayashi, K., Hishikawa, A., Hashiguchi, A., Azegami, T., Yoshimoto, N., Nakamichi, R., Tokuyama, H. & Itoh, H., 2020 Dec 1, In : Scientific reports. 10, 1, 237.

Research output: Contribution to journalArticle

Open Access

Characteristics of leiomyosarcoma: Induction of hematogenous metastasis by isolated uterine mesenchymal tumor stem-like cells

Hayashi, T., Sano, K., Ichimura, T., Kanai, Y., Zharhary, D., Aburatani, H., Yaegashi, N. & Konishi, I., 2020, In : Anticancer research. 40, 3, p. 1255-1265 11 p.

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Open Access

Clinical, Endoscopic, and Pathological Characteristics of Immune Checkpoint Inhibitor-Induced Gastroenterocolitis

Hayashi, Y., Hosoe, N., Takabayashi, K., Limpias Kamiya, K. J. L., Tsugaru, K., Shimozaki, K., Hirata, K., Fukuhara, K., Fukuhara, S., Mutaguchi, M., Sujino, T., Sukawa, Y., Hamamoto, Y., Naganuma, M., Takaishi, H., Shimoda, M., Ogata, H. & Kanai, T., 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets

Wagatsuma, T., Nagai-Okatani, C., Matsuda, A., Masugi, Y., Imaoka, M., Yamazaki, K., Sakamoto, M. & Kuno, A., 2020 Mar 13, In : Frontiers in Oncology. 10, 338.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Effect of surgical margin width after R0 resection for intrahepatic cholangiocarcinoma: A nationwide survey of the Liver Cancer Study Group of Japan

Watanabe, Y., Matsuyama, Y., Izumi, N., Kubo, S., Kokudo, N., Sakamoto, M., Shiina, S., Takayama, T., Nakashima, O. & Kudo, M., 2020 May, In : Surgery (United States). 167, 5, p. 793-802 10 p.

Research output: Contribution to journalArticle

Establishment of diagnostic criteria for upper urinary tract urothelial carcinoma based on genome-wide DNA methylation analysis

Fujimoto, M., Arai, E., Tsumura, K., Yotani, T., Yamada, Y., Takahashi, Y., Maeshima, A. M., Fujimoto, H., Yoshida, T. & Kanai, Y., 2020, In : Epigenetics. p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access

Hidden disseminated extracutaneous AIDS-related Kaposi sarcoma

Kawakami, N., Namkoong, H., Shimoda, M., Kotani, H., Fujiwara, H. & Hasegawa, N., 2020, In : IDCases. 19, e00716.

Research output: Contribution to journalArticle

Open Access

How I do it: Endoscopic diagnosis for superficial non-ampullary duodenal epithelial tumors

Nakayama, A., Kato, M., Takatori, Y., Shimoda, M., Mizutani, M., Tsutsumi, K., Kiguchi, Y., Akimoto, T., Sasaki, M., Mutaguchi, M., Takabayashi, K., Maehata, T., Ochiai, Y., Kanai, T. & Yahagi, N., 2020 Mar 1, In : Digestive Endoscopy. 32, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection

Dokoshi, T., Zhang, L. J., Li, F., Nakatsuji, T., Butcher, A., Yoshida, H., Shimoda, M., Okada, Y. & Gallo, R. L., 2020 Jan 7, In : Cell Reports. 30, 1, p. 61-68.e4

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Open Access

IL-6 and G-CSF production resulting from lung cancer in an HIV patient

Kawakami, N., Namkoong, H., Masaki, K., Kurebayashi, Y., Shimoda, M., Kotani, H., Fujiwara, H. & Hasegawa, N., 2020, In : IDCases. 19, e00693.

Research output: Contribution to journalArticle

Open Access

Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma

Shima, T., Shimoda, M., Shigenobu, T., Ohtsuka, T., Nishimura, T., Emoto, K., Hayashi, Y., Iwasaki, T., Abe, T., Asamura, H. & Kanai, Y., 2020 Feb 1, In : Cancer science. 111, 2, p. 727-738 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Liver Resection for Multiple Hepatocellular Carcinomas: A Japanese Nationwide Survey

Liver Cancer Study Group of Japan, 2020 Jul 1, In : Annals of surgery. 272, 1, p. 145-154 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, 2020 Feb 6, In : Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journalArticle

Open Access
71 Citations (Scopus)

Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis

Fujita, Y., Matsuda, S., Sasaki, Y., Masugi, Y., Kitago, M., Yagi, H., Abe, Y., Shinoda, M., Tokino, T., Sakamoto, M. & Kitagawa, Y., 2020 Feb 1, In : Cancer science. 111, 2, p. 739-748 10 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Primary Peritoneal Low-grade Serous Carcinoma in a Patient with Lynch Syndrome: A Case Report

Makiuchi, S., Yoshida, H., Ishikawa, M., Kojima, N., Kanai, Y. & Kato, T., 2020 Jul 1, In : International Journal of Gynecological Pathology. 39, 4, p. 327-332 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access

Quantification of intratumoral collagen and elastin fibers within hepatocellular carcinoma tissues finds correlations with clinico-patho-radiological features

Maehara, J., Masugi, Y., Abe, T., Tsujikawa, H., Kurebayashi, Y., Ueno, A., Ojima, H., Okuda, S., Jinzaki, M., Shinoda, M., Kitagawa, Y., Oda, Y., Honda, H. & Sakamoto, M., 2020 May 1, In : Hepatology Research. 50, 5, p. 607-619 13 p.

Research output: Contribution to journalArticle

Report of the 20th Nationwide follow-up survey of primary liver cancer in Japan

Kudo, M., Izumi, N., Kubo, S., Kokudo, N., Sakamoto, M., Shiina, S., Tateishi, R., Nakashima, O., Murakami, T., Matsuyama, Y., Takahashi, A., Miyata, H. & Takayama, T., 2020 Jan 1, In : Hepatology Research. 50, 1, p. 15-46 32 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Significance of the surgical hepatic resection margin in patients with a single hepatocellular carcinoma

on behalf of the Liver Cancer Study Group of Japan, 2020 Jan 1, In : British Journal of Surgery. 107, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults

Watanabe, T., Honda, T., Totsuka, H., Yoshida, M., Tanioka, M., Shiraishi, K., Shimada, Y., Arai, E., Ushiama, M., Tamura, K., Yoshida, T., Kanai, Y. & Kohno, T., 2020 Jul 1, In : Breast Cancer Research and Treatment. 182, 2, p. 491-502 12 p.

Research output: Contribution to journalArticle

Telomerase reverse transcriptase (TERT) promoter mutation correlated with intratumoral heterogeneity in hepatocellular carcinoma

Kwa, W. T., Effendi, K., Yamazaki, K., Kubota, N., Hatano, M., Ueno, A., Masugi, Y. & Sakamoto, M., 2020, (Accepted/In press) In : Pathology international.

Research output: Contribution to journalArticle

2019

A Case of Aggressive Recurrent Intracranial Subdural Hematoma Associated with Angiosarcoma Originating from the Skull

Kanazawa, T., Miwa, T., Akiyama, T., Ohara, K., Kosugi, K., Nishimoto, M. & Yoshida, K., 2019 Jun, In : World neurosurgery. 126, p. 120-123 4 p.

Research output: Contribution to journalArticle

Acute Interstitial Nephritis With Karyomegalic Epithelial Cells After Nivolumab Treatment—Two Case Reports

Ryuzaki, M., Tokuyama, H., Uchiyama, K., Nakaya, H., Hasegawa, K., Miyashita, K., Konishi, K., Hashiguchi, A., Wakino, S. & Itoh, H., 2019 Jun 1, In : Clinical Medicine Insights: Case Reports. 12

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

A grading system that predicts the risk of dialysis induction in IgA nephropathy patients based on the combination of the clinical and histological severity

for The Special IgA Nephropathy Study Group, 2019 Jan 22, In : Clinical and experimental nephrology. 23, 1, p. 16-25 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Association Between CD133, CD44, and Nestin Expression and Prognostic Factors in High-Grade Meningioma

Kamamoto, D., Saga, I., Ohara, K., Yoshida, K. & Sasaki, H., 2019 Jan 1, (Accepted/In press) In : World Neurosurgery.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Characterization of spatial distribution of tumor-infiltrating CD8+ T cells refines their prognostic utility for pancreatic cancer survival

Masugi, Y., Abe, T., Ueno, A., Fujii-Nishimura, Y., Ojima, H., Endo, Y., Fujita, Y., Kitago, M., Shinoda, M., Kitagawa, Y. & Sakamoto, M., 2019 Oct 1, In : Modern Pathology. 32, 10, p. 1495-1507 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Clinical and endoscopic findings to assist the early detection of duodenal adenoma and adenocarcinoma

Matsuzaki, J., Suzuki, H., Shimoda, M., Mori, H., Fukuhara, S., Miyoshi, S., Masaoka, T., Iwao, Y., Kanai, Y. & Kanai, T., 2019 Mar 1, In : United European Gastroenterology Journal. 7, 2, p. 250-260 11 p.

Research output: Contribution to journalArticle

Clinicopathologic features of hormone-receptor-positive breast cancer patients with late recurrence

Murata, T., Jinno, H., Takahashi, M., Shimoda, M., Hayashida, T., Kameyama, K. & Kitagawa, Y., 2019 Jan 1, In : Breast Journal. 25, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Comprehensive genetic analysis of cholangiolocellular carcinoma with a coexistent hepatocellular carcinoma-like area and metachronous hepatocellular carcinoma

Kawai-Kitahata, F., Asahina, Y., Kaneko, S., Tsuchiya, J., Sato, A., Miyoshi, M., Tsunoda, T., Inoue-Shinomiya, E., Murakawa, M., Nitta, S., Itsui, Y., Nakagawa, M., Azuma, S., Kakinuma, S., Tanabe, M., Sugawara, E., Takemoto, A., Ojima, H., Sakamoto, M., Muraoka, M. & 4 others, Takano, S., Maekawa, S., Enomoto, N. & Watanabe, M., 2019 Dec 1, In : Hepatology Research. 49, 12, p. 1466-1474 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Deregulation of the histone lysine-specific demethylase 1 is involved in human hepatocellular carcinoma

Kim, S., Bolatkan, A., Kaneko, S., Ikawa, N., Asada, K., Komatsu, M., Hayami, S., Ojima, H., Abe, N., Yamaue, H. & Hamamoto, R., 2019 Dec, In : Biomolecules. 9, 12, 810.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Disseminated histoplasmosis from a calcified lung nodule after long-term corticosteroid therapy in an elderly Japanese patient: A case report

Kobayashi, K., Asakura, T., Kawada, I., Hasegawa, H., Chubachi, S., Ohara, K., Kuramoto, J., Sugiura, H., Fujishima, S., Iwata, S., Umeyama, T., Katano, H., Uwamino, Y., Miyazaki, Y., Kamei, K., Hasegawa, N. & Betsuyaku, T., 2019 Apr 1, In : Medicine. 98, 17, p. e15264

Research output: Contribution to journalArticle

Open Access

Endoscopic Endonasal Removal of Large Calcified Pituitary Adenoma: Case Report and Review of the Literature

Murase, M., Toda, M., Ohara, K., Ishihara, E. & Yoshida, K., 2019 Mar 1, In : World Neurosurgery. 123, p. 239-243 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Endothelial-mesenchymal transition drives expression of CD44 variant and xCT in pulmonary hypertension

Isobe, S., Kataoka, M., Endo, J., Moriyama, H., Okazaki, S., Tsuchihashi, K., Katsumata, Y., Yamamoto, T., Shirakawa, K., Yoshida, N., Shimoda, M., Chiba, T., Masuko, T., Hakamata, Y., Kobayashi, E., Saya, H., Fukuda, K. & Sano, M., 2019 Jan 1, In : American journal of respiratory cell and molecular biology. 61, 3, p. 367-379 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Establishment of a model of sentinel lymph node metastasis using immunodeficient swine

Kurihara, T., Matsuda, S., Nakamura, Y., Suzuki, S., Fuchimoto, D., Onishi, A., Saeki, K., Nakagawa, T., Fujiwara, R., Kamata, M., Kuramoto, J., Kameyama, K., Sekino, M., Kusakabe, M., Hayashida, T., Jinno, H. & Kitagawa, Y., 2019 Dec 1, In : Scientific reports. 9, 1, 7923.

Research output: Contribution to journalArticle

Open Access

Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma

Saito, Y., Muramatsu, T., Kanai, Y., Ojima, H., Sukeda, A., Hiraoka, N., Arai, E., Sugiyama, Y., Matsuzaki, J., Uchida, R., Yoshikawa, N., Furukawa, R. & Saito, H., 2019 Apr 23, In : Cell Reports. 27, 4, p. 1265-1276.e4

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Establishment of permutation for cancer risk estimation in the urothelium based on genome-wide DNA methylation analysis

Tsumura, K., Arai, E., Tian, Y., Shibuya, A., Nishihara, H., Yotani, T., Yamada, Y., Takahashi, Y., Maeshima, A. M., Fujimoto, H., Nakagawa, T., Kume, H., Homma, Y., Yoshida, T. & Kanai, Y., 2019 Nov 25, In : Carcinogenesis. 40, 11, p. 1308-1319 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genome-wide DNA methylation profile of early-onset endometrial cancer: Its correlation with genetic aberrations and comparison with late-onset endometrial cancer

Makabe, T., Arai, E., Hirano, T., Ito, N., Fukamachi, Y., Takahashi, Y., Hirasawa, A., Yamagami, W., Susumu, N., Aoki, D. & Kanai, Y., 2019 Jul 4, In : Carcinogenesis. 40, 5, p. 611-623 13 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

Nakamoto, N., Sasaki, N., Aoki, R., Miyamoto, K., Suda, W., Teratani, T., Suzuki, T., Koda, Y., Chu, P. S., Taniki, N., Yamaguchi, A., Kanamori, M., Kamada, N., Hattori, M., Ashida, H., Sakamoto, M., Atarashi, K., Narushima, S., Yoshimura, A., Honda, K. & 2 others, Sato, T. & Kanai, T., 2019 Mar 1, In : Nature Microbiology. 4, 3, p. 492-503 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Immunoglobulin G4-Related Disease Arising from the Bladder Wall

Kufukihara, R., Niwa, N., Mizuno, R., Ohara, K., Mikami, S., Kikuchi, E. & Oya, M., 2019 Nov 1, In : Urologia Internationalis. 103, 4, p. 488-490 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Impact of Advanced Age on Survival in Patients Undergoing Resection of Hepatocellular Carcinoma: Report of a Japanese Nationwide Survey

Liver Cancer Study Group of Japan, 2019 Apr 1, In : Annals of surgery. 269, 4, p. 692-699 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Interleukin-13 and its signaling pathway is associated with obesity-related colorectal tumorigenesis

Matsui, S., Okabayashi, K., Tsuruta, M., Shigeta, K., Seishima, R., Ishida, T., Kondo, T., Suzuki, Y., Hasegawa, H., Shimoda, M., Sugimoto, S., Sato, T. & Kitagawa, Y., 2019 Jul, In : Cancer science. 110, 7, p. 2156-2165 10 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)