Department of Internal Medicine

Research Output

2020

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Mizuno, S., Ono, K., Mikami, Y., Naganuma, M., Fukuda, T., Minami, K., Masaoka, T., Terada, S., Yoshida, T., Saigusa, K., Hirahara, N., Miyata, H., Suda, W., Hattori, M. & Kanai, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Open Access

A case of cerebral infarction caused by painless acute aortic dissection in autosomal dominant polycystic kidney disease

Yamaguchi, S., Wakino, S., Tokuyama, H. & Itoh, H., 2020 May 1, In : CEN case reports. 9, 2, p. 177-181 5 p.

Research output: Contribution to journalArticle

A Case of Esophageal Xanthoma with Epithelial Reactive Inflammation with a Characteristic Finding of Narrow-Band Imaging Magnifying Endoscopy

Mori, H., Kato, M. & Uraoka, T., 2020 Jan 1, In : Digestive Diseases. 38, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

A consideration for efficient unrelated hematopoietic stem cell source acquisition—from an experience of Japan

Nishiwaki, S., Miyamura, K., Kanda, Y., Takanashi, M., Uchida, N., Fukuda, T., Ikegame, K., Ohashi, K., Eto, T., Ozawa, Y., Shiratori, S., Iwato, K., Matsuoka, K. I., Hidaka, M., Ichinohe, T., Atsuta, Y., Kodera, Y. & Okamoto, S., 2020 Mar 1, In : Bone Marrow Transplantation. 55, 3, p. 657-660 4 p.

Research output: Contribution to journalLetter

Adherence to antihypertensive medication and its predictors among non-elderly adults in Japan

Nishimura, S., Kumamaru, H., Shoji, S., Sawano, M., Kohsaka, S. & Miyata, H., 2020 Jan 1, (Accepted/In press) In : Hypertension Research.

Research output: Contribution to journalArticle

Adrenal cortex hypoxia modulates aldosterone production in heart failure

Yamashita, K., Ito, K., Endo, J., Matsuhashi, T., Katsumata, Y., Yamamoto, T., Shirakawa, K., Isobe, S., Kataoka, M., Yoshida, N., Goto, S., Moriyama, H., Kitakata, H., Mitani, F., Fukuda, K., Goda, N., Ichihara, A. & Sano, M., 2020 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Open Access

Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia conducted in Japan during the past quarter century

Yanada, M., Takami, A., Yamasaki, S., Arai, Y., Konuma, T., Uchida, N., Najima, Y., Fukuda, T., Tanaka, M., Ozawa, Y., Ikegame, K., Takanashi, M., Ichinohe, T., Okamoto, S., Atsuta, Y. & Yano, S., 2020 Jun 1, In : Annals of Hematology. 99, 6, p. 1351-1360 10 p.

Research output: Contribution to journalArticle

Antigen-driven selection of antibodies against SSA, SSB and the centromere complex', including a novel antigen, MIS12 complex, in human salivary glands

Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., Kato, S., Tsunoda, K., Arase, H. & Takeuchi, T., 2020 Jan 1, In : Annals of the rheumatic diseases. 79, 1, p. 150-158 9 p.

Research output: Contribution to journalArticle

Open Access

Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn's disease in Japanese and Korean patients: The OPERA study

Saruta, M., Park, D. I., Kim, Y. H., Yang, S. K., Jang, B. I., Cheon, J. H., Im, J. P., Kanai, T., Katsuno, T., Ishiguro, Y., Nagaoka, M., Isogawa, N., Li, Y., Banerjee, A., Ahmad, A., Hassan-Zahraee, M., Clare, R., Gorelick, K. J., Cataldi, F., Watanabe, M. & 1 others, Hibi, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

Open Access

Anti-RNP antibodies delineate a subgroup of myositis: A systematic retrospective study on 46 patients

Wesner, N., Uruha, A., Suzuki, S., Mariampillai, K., Granger, B., Champtiaux, N., Rigolet, A., Schoindre, Y., Lejeune, S., Guillaume-Jugnot, P., Vautier, M., Hervier, B., Simon, A., Granier, F., Gallay, L., Nishino, I., Benveniste, O. & Allenbach, Y., 2020 Mar, In : Autoimmunity Reviews. 19, 3, 102465.

Research output: Contribution to journalLetter

Antisynthetase myopathy

Suzuki, S., 2020 Jan 1, In : Clinical Neurology. 60, 3, p. 175-180 6 p.

Research output: Contribution to journalArticle

Open Access

Anti-TSLP antibodies: Targeting a master regulator of type 2 immune responses

Nakajima, S., Kabata, H., Kabashima, K. & Asano, K., 2020 Apr, In : Allergology International. 69, 2, p. 197-203 7 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

A Phase II Study of Regorafenib With a Lower Starting Dose in Patients With Metastatic Colorectal Cancer: Exposure–Toxicity Analysis of Unbound Regorafenib and Its Active Metabolites (RESET Trial)

Suzuki, T., Sukawa, Y., Imamura, C. K., Masuishi, T., Satake, H., Kumekawa, Y., Funakoshi, S., Kotaka, M., Horie, Y., Kawai, S., Okuda, H., Terazawa, T., Kondoh, C., Kato, K., Yoshimura, K., Ishikawa, H., Hamamoto, Y., Boku, N., Takaishi, H. & Kanai, T., 2020 Mar, In : Clinical Colorectal Cancer. 19, 1, p. 13-21.e3

Research output: Contribution to journalArticle

Appropriateness of Transcatheter Aortic Valve Replacement: Insight from the OCEAN-TAVI Registry

Inohara, T., Vemulapalli, S., Kohsaka, S., Yashima, F., Watanabe, Y., Shirai, S., Tada, N., Araki, M., Naganuma, T., Yamanaka, F., Ueno, H., Tabata, M., Mizutani, K., Higashimori, A., Takagi, K., Yamamoto, M., Shimizu, H., Fukuda, K. & Hayashida, K., 2020 Jan 1, (Accepted/In press) In : Circulation: Cardiovascular Quality and Outcomes. e006146.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Appropriate timing for a biochemical evaluation after adrenalectomy for unilateral aldosterone-producing adenoma

Takamatsu, K., Takeda, T., Hattori, S., Tanaka, N., Morita, S., Matsumoto, K., Kosaka, T., Mizuno, R., Shinojima, T., Kikuchi, E., Asanuma, H., Kurihara, I., Itoh, H. & Oya, M., 2020 Jan 1, (Accepted/In press) In : Clinical Endocrinology. 92, 6, p. 503-508 6 p.

Research output: Contribution to journalArticle

A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort

Ohwada, C., Sakaida, E., Igarashi, A., Kobayashi, T., Doki, N., Mori, T., Kato, J., Koda, Y., Kanamori, H., Tanaka, M., Tachibana, T., Fujisawa, S., Nakajima, Y., Numata, A., Toyosaki, M., Aoyama, Y., Onizuka, M., Hagihara, M., Koyama, S., Kanda, Y. & 9 others, Nakasone, H., Shimizu, H., Kato, S., Watanabe, R., Shono, K., Sakai, R., Saito, T., Nakaseko, C. & Okamoto, S., 2020 Jan, In : Biology of Blood and Marrow Transplantation. 26, 1, p. 162-170 9 p.

Research output: Contribution to journalArticle

Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Hayashi, K., Hishikawa, A., Hashiguchi, A., Azegami, T., Yoshimoto, N., Nakamichi, R., Tokuyama, H. & Itoh, H., 2020 Dec 1, In : Scientific reports. 10, 1, 237.

Research output: Contribution to journalArticle

Open Access

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: The Hisayama Study

Inaishi, J., Saisho, Y., Hirakawa, Y., Yoshida, D., Hata, J., Mukai, N., Watanabe, Y., Oda, Y., Itoh, H. & Ninomiya, T., 2020 Jan 1, (Accepted/In press) In : Journal of Diabetes Investigation.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Associations among liver disease, serum lipid profile, body mass index, ketonuria, meal skipping, and the alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 genotypes in Japanese men with alcohol dependence

Yokoyama, A., Taniki, N., Nakamoto, N., Tomita, K., Hara, S., Mizukami, T., Maruyama, K. & Yokoyama, T., 2020 May 1, In : Hepatology Research. 50, 5, p. 565-577 13 p.

Research output: Contribution to journalArticle

Atrial Fibrillation-Associated Ischemic Stroke Patients with Prior Anticoagulation Have Higher Risk for Recurrent Stroke

Tanaka, K., Koga, M., Lee, K. J., Kim, B. J., Park, E. L., Lee, J., Mizoguchi, T., Yoshimura, S., Cha, J. K., Lee, B. C., Nakahara, J., Suzuki, N., Bae, H. J. & Toyoda, K., 2020 Apr 1, In : Stroke. p. 1150-1157 8 p.

Research output: Contribution to journalArticle

Open Access

A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus

Hanaoka, H., Nishimoto, T., Okazaki, Y., Takeuchi, T. & Kuwana, M., 2020 Apr 21, In : Arthritis Research and Therapy. 22, 1, 88.

Research output: Contribution to journalArticle

Open Access
Open Access

Author reply: Early operation and establishment of an endocarditis team

Ko, S., Uno, S. & Kohsaka, S., 2020 Feb 1, In : Internal Medicine. 59, 3, 1 p.

Research output: Contribution to journalLetter

Open Access

Autologous hematopoietic cell transplantation for acute myeloid leukemia in adults: 25 years of experience in Japan

Yanada, M., Takami, A., Mizuno, S., Mori, J., Chou, T., Usuki, K., Uchiyama, H., Amano, I., Fujii, S., Miyamoto, T., Saito, T., Kamimura, T., Ichinohe, T., Fukuda, T., Okamoto, S., Atsuta, Y. & Yano, S., 2020 Jan 1, In : International journal of hematology. 111, 1, p. 93-102 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Biomarkers for disease flare in patients with adult-onset Still's disease undergoing treatment with tocilizumab

Yamada, H., Kaneko, Y., Tamai, H. & Takeuchi, T., 2020 Feb 1, In : Rheumatology (Oxford, England). 59, 2, p. 440-442 3 p.

Research output: Contribution to journalArticle

CDAI and DAS28 in the management of rheumatoid arthritis in clinical practice

Takanashi, S., Kaneko, Y. & Takeuchi, T., 2020 May 1, In : Annals of the rheumatic diseases. 79, 5, p. 671-674 4 p.

Research output: Contribution to journalLetter

Characteristics of chronic obstructive pulmonary disease patients with pulmonary hypertension assessed by echocardiography in a three-year observational cohort study

Nakayama, S., Chubachi, S., Sakurai, K., Irie, H., Tsutsumi, A., Hashiguchi, M., Itabashi, Y., Murata, M., Nakamura, H., Asano, K. & Fukunaga, K., 2020 Jan 1, In : International Journal of COPD. 15, p. 487-499 13 p.

Research output: Contribution to journalArticle

Open Access

Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma

Kawasaki, K., Fujii, M., Sugimoto, S., Ishikawa, K., Matano, M., Ohta, Y., Toshimitsu, K., Takahashi, S., Hosoe, N., Sekine, S., Kanai, T. & Sato, T., 2020 Feb, In : Gastroenterology. 158, 3, p. 638-651.e8

Research output: Contribution to journalArticle

3 Citations (Scopus)

Circulating FGF23 is not associated with cardiac dysfunction, atherosclerosis, infection or inflammation in hemodialysis patients

Takashi, Y., Wakino, S., Minakuchi, H., Ishizu, M., Kuroda, A., Shima, H., Tashiro, M., Miya, K., Okada, K., Minakuchi, J., Kawashima, S., Matsuhisa, M., Matsumoto, T. & Fukumoto, S., 2020 Jan 1, In : Journal of Bone and Mineral Metabolism. 38, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Clinical and endoscopic characteristics of pyogenic granuloma in the small intestine: A case series with literature review

Hayashi, Y., Dr, N. H., Takabayashi, K., Limpias Kamiya, K. J. L., Mutaguchi, M., Miyanaga, R., Hirata, K., Fukuhara, S., Mikami, Y., Sujino, T., Masugi, Y., Naganuma, M., Ogata, H. & Kanai, T., 2020 Feb 15, In : Internal Medicine. 59, 4, p. 501-505 5 p.

Research output: Contribution to journalReview article

Open Access

Clinical characteristics of cancer-associated myositis complicated by interstitial lung disease: A large-scale multicentre cohort study

Kaneko, Y., Nunokawa, T., Taniguchi, Y., Yamaguchi, Y., Gono, T., Masui, K., Kawakami, A., Kawaguchi, Y., Sato, S., Kuwana, M., Okano, Y., Nishina, N., Tamura, M., Kirino, Y., Ikeda, K., Kikuchi, J., Kubo, M., Tanino, Y., Kaieda, S., Naniwa, T. & 26 others, Watanabe, M., Harada, T., Ukichi, T., Kazuyori, T., Kameda, H., Kaburaki, M., Matsuzawa, Y., Yoshida, S., Yoshioka, Y., Hirai, T., Asakawa, K., Wada, Y., Ishii, K., Fujiwara, S., Saraya, T., Morimoto, K., Hara, T., Suzuki, H., Shibuya, H., Muro, Y., Aki, R., Shibayama, T., Ohshima, S., Yasuda, Y., Terada, M. & Kawahara, Y., 2020 Jan 1, In : Rheumatology (United Kingdom). 59, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

Clinical characteristics of human herpesvirus-6 myelitis after allogeneic hematopoietic stem cell transplantation and its favorable outcome by early intervention

Shiroshita, K., Mori, T., Kato, J., Sakurai, M., Koda, Y., Abe, R., Murakami, K., Sumiya, C., Fujita, S., Yamaguchi, K., Yamazaki, R., Nakayama, H., Suzuki, S., Nakahara, J. & Okamoto, S., 2020 May 1, In : Bone Marrow Transplantation. 55, 5, p. 939-945 7 p.

Research output: Contribution to journalArticle

Clinical implications with tolvaptan on monitored bioimpedance-defined fluid status in patients with cirrhotic ascites: An observational study

Shiba, S., Chu, P. S., Nakamoto, N., Yamataka, K., Taniki, N., Ojiro, K., Yamaguchi, A., Morikawa, R., Yoshida, A., Ikura, A., Ebinuma, H., Saito, H. & Kanai, T., 2020 Mar 5, In : BMC Gastroenterology. 20, 1, 53.

Research output: Contribution to journalArticle

Open Access

Continuous regional arterial infusion versus intravenous administration of the protease inhibitor nafamostat mesilate for predicted severe acute pancreatitis: a multicenter, randomized, open-label, phase 2 trial

Hirota, M., Shimosegawa, T., Kitamura, K., Takeda, K., Takeyama, Y., Mayumi, T., Ito, T., Takenaka, M., Iwasaki, E., Sawano, H., Ishida, E., Miura, S., Masamune, A., Nakai, Y., Mitoro, A., Maguchi, H., Kimura, K., Sanuki, T., Ito, T., Haradome, H. & 9 others, Kozaka, K., Gabata, T., Kataoka, K., Hirota, M., Isaji, S., Nakamura, R., Yamagiwa, K., Kayaba, C. & Ikeda, K., 2020 Mar 1, In : Journal of gastroenterology. 55, 3, p. 342-352 11 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Controlling nutritional status score as a predictive marker for patients with implantable left ventricular assist device

Saito, A., Amiya, E., Hatano, M., Shiraishi, Y., Nitta, D., Minatsuki, S., Maki, H., Hosoya, Y., Tsuji, M., Bujo, C., Nawata, K., Kinoshita, O., Kimura, M., Endo, M., Kagami, Y., Nemoto, M., Ikeda, Y., Morita, H., Ono, M. & Komuro, I., 2020 Feb 1, In : ASAIO Journal. p. 166-172 7 p.

Research output: Contribution to journalArticle

Open Access

Correction: Worldwide Network for Blood and Marrow Transplantation (WBMT) perspective: the role of biosimilars in hematopoietic cell transplant: current opportunities and challenges in low- and lower-middle income countries (Bone Marrow Transplantation, (2020), 55, 4, (698-707), 10.1038/s41409-019-0658-2)

Muhsen, I. N., Hashmi, S. K., Niederwieser, D., Kroeger, N., Agrawal, S., Pasquini, M. C., Atsuta, Y., Ballen, K. K., Seber, A., Saber, W., Kharfan-Dabaja, M. A., Rasheed, W., Okamoto, S., Khera, N., Wood, W. A., Koh, M. B. C., Greinix, H., Kodera, Y., Szer, J., Horowitz, M. M. & 2 others, Weisdorf, D. & Aljurf, M., 2020 Apr 1, In : Bone Marrow Transplantation. 55, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Open Access

Current Status and Needs of Long-Term Follow-Up Clinics for Hematopoietic Cell Transplantation Survivors: Results of a Nationwide Survey in Japan

Kurosawa, S., Mori, A., Tsukagoshi, M., Onishi, Y., Ohwada, C., Mori, T., Goto, H., Asano-Mori, Y., Nawa, Y., Hino, M., Fukuchi, T., Mori, Y., Yamahana, R., Inamoto, Y. & Fukuda, T., 2020 May, In : Biology of Blood and Marrow Transplantation. 26, 5, p. 949-955 7 p.

Research output: Contribution to journalArticle

Cysteinyl leukotriene metabolism of human eosinophils in allergic disease

Miyata, J., Fukunaga, K., Kawashima, Y., Ohara, O. & Arita, M., 2020 Jan, In : Allergology International. 69, 1, p. 28-34 7 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)
Open Access

DNA damage and expression of DNA methylation modulators in urine-derived cells of patients with hypertension and diabetes

Hishikawa, A., Hayashi, K., Yoshimoto, N., Nakamichi, R., Homma, K. & Itoh, H., 2020 Feb 25, In : Scientific reports. 10, 1, 1 p.

Research output: Contribution to journalArticle

Open Access

Donor heme oxygenase-1 promoter gene polymorphism predicts survival after unrelated bone marrow transplantation for high-risk patients

Horio, T., Morishita, E., Mizuno, S., Uchino, K., Hanamura, I., Espinoza, J. L., Morishima, Y., Kodera, Y., Onizuka, M., Kashiwase, K., Fukuda, T., Doki, N., Miyamura, K., Mori, T., Nakao, S. & Takami, A., 2020 Feb, In : Cancers. 12, 2, 424.

Research output: Contribution to journalArticle

Open Access

Double-Blind Randomized Phase 3 Study Comparing Esaxerenone (CS-3150) and Eplerenone in Patients With Essential Hypertension (ESAX-HTN Study)

Ito, S., Itoh, H., Rakugi, H., Okuda, Y., Yoshimura, M. & Yamakawa, S., 2020 Jan 1, In : Hypertension (Dallas, Tex. : 1979). 75, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Effect of cosyntropin during adrenal venous sampling on subtype of primary aldosteronism: Analysis of surgical outcome

on behalf of JPAS/JRAS Study Group, 2020 Jan 1, In : European journal of endocrinology. 182, 3, p. 265-273 9 p.

Research output: Contribution to journalArticle

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., Okano, H., Nabeshima, Y. I., Imai, S. I., Yasui, M., Tsubota, K. & Itoh, H., 2020 Jan 1, In : Endocrine journal. 67, 2, p. 153-160 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Effects of exercise on residual renal function in patients undergoing peritoneal dialysis: A post-hoc analysis of a randomized controlled trial

Uchiyama, K., Washida, N., Morimoto, K., Muraoka, K., Nakayama, T., Adachi, K., Kasai, T., Miyashita, K., Wakino, S. & Itoh, H., 2020 Jan 1, (Accepted/In press) In : Therapeutic Apheresis and Dialysis.

Research output: Contribution to journalArticle

Effects of vedolizumab in Japanese patients with Crohn’s disease: a prospective, multicenter, randomized, placebo-controlled Phase 3 trial with exploratory analyses

Watanabe, K., Motoya, S., Ogata, H., Kanai, T., Matsui, T., Suzuki, Y., Shikamura, M., Sugiura, K., Oda, K., Hori, T., Araki, T., Watanabe, M. & Hibi, T., 2020 Mar 1, In : Journal of gastroenterology. 55, 3, p. 291-306 16 p.

Research output: Contribution to journalArticle

Open Access