Department of Internal Medicine

Research Output

2020

[123I]-IMP single-photon emission computed tomography imaging in visual snow syndrome: A case series

Shibata, M., Tsutsumi, K., Iwabuchi, Y., Kameyama, M., Takizawa, T., Nakahara, T., Fujiwara, H., Jinzaki, M., Nakahara, J. & Dodick, D. W., 2020, (Accepted/In press) In : Cephalalgia.

Research output: Contribution to journalArticle

Open Access

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Mizuno, S., Ono, K., Mikami, Y., Naganuma, M., Fukuda, T., Minami, K., Masaoka, T., Terada, S., Yoshida, T., Saigusa, K., Hirahara, N., Miyata, H., Suda, W., Hattori, M. & Kanai, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A 3-Year Overall Survival Update From a Phase 2 Study of Chemoselection With DCF and Subsequent Conversion Surgery for Locally Advanced Unresectable Esophageal Cancer

Yokota, T., Kato, K., Hamamoto, Y., Tsubosa, Y., Ogawa, H., Ito, Y., Hara, H., Ura, T., Kojima, T., Chin, K., Hironaka, S., Kii, T., Kojima, Y., Akutsu, Y., Matsushita, H., Kawakami, K., Mori, K., Makiuchi, T., Nagumo, R. & Kitagawa, Y., 2020 Feb 1, In : Annals of Surgical Oncology. 27, 2, p. 460-467 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A Case of Esophageal Xanthoma with Epithelial Reactive Inflammation with a Characteristic Finding of Narrow-Band Imaging Magnifying Endoscopy

Mori, H., Kato, M. & Uraoka, T., 2020 Jan 1, In : Digestive Diseases. 38, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

A case of intrahepatic cholangiocellular carcinoma due to thorotrast deposition, well-controlled by radiofrequency ablation therapy

Taniki, N., Nakamoto, N., Yoshida, A., Chu, P. S., Ikura, A., Yamataka, K., Morikawa, R., Shiba, S., Yamaguchi, A., Usui, S., Ojiro, K., Ebinuma, H., Saito, H., Kubota, N., Masugi, Y., Sakamto, M. & Kanai, T., 2020, In : Acta Hepatologica Japonica. 61, 5, p. 262-269 8 p.

Research output: Contribution to journalArticle

Open Access

Achieving sequential therapy in advanced gastric cancer: the importance of appropriate patient management for the elderly and/or those with ascites

Hamamoto, Y., Piao, Y. & Makiyama, A., 2020 May 1, In : Gastric Cancer. 23, 3, p. 363-372 10 p.

Research output: Contribution to journalReview article

Open Access

A consideration for efficient unrelated hematopoietic stem cell source acquisition—from an experience of Japan

Nishiwaki, S., Miyamura, K., Kanda, Y., Takanashi, M., Uchida, N., Fukuda, T., Ikegame, K., Ohashi, K., Eto, T., Ozawa, Y., Shiratori, S., Iwato, K., Matsuoka, K. I., Hidaka, M., Ichinohe, T., Atsuta, Y., Kodera, Y. & Okamoto, S., 2020 Mar 1, In : Bone Marrow Transplantation. 55, 3, p. 657-660 4 p.

Research output: Contribution to journalLetter

Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections

for the Keio Donner Project, 2020 Oct, In : International Journal of Infectious Diseases. 99, p. 19-22 4 p.

Research output: Contribution to journalArticle

Open Access

ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice

Suzuki, S., Ishii, M., Asakura, T., Namkoong, H., Okamori, S., Yagi, K., Kamata, H., Kusumoto, T., Kagawa, S., Hegab, A. E., Yoda, M., Horiuchi, K., Hasegawa, N. & Betsuyaku, T., 2020 Jun, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 6, p. L1172-L1182

Research output: Contribution to journalArticle

Adenosine leakage from perforin-burst extracellular vesicles inhibits perforin secretion by cytotoxic T-lymphocytes

Tadokoro, H., Hirayama, A., Kudo, R., Hasebe, M., Yoshioka, Y., Matsuzaki, J., Yamamoto, Y., Sugimoto, M., Soga, T. & Ochiya, T., 2020 Apr, In : PloS one. 15, 4, e0231430.

Research output: Contribution to journalArticle

Open Access

Adherence to antihypertensive medication and its predictors among non-elderly adults in Japan

Nishimura, S., Kumamaru, H., Shoji, S., Sawano, M., Kohsaka, S. & Miyata, H., 2020 Jul 1, In : Hypertension Research. 43, 7, p. 705-714 10 p.

Research output: Contribution to journalArticle

Adrenal cortex hypoxia modulates aldosterone production in heart failure

Yamashita, K., Ito, K., Endo, J., Matsuhashi, T., Katsumata, Y., Yamamoto, T., Shirakawa, K., Isobe, S., Kataoka, M., Yoshida, N., Goto, S., Moriyama, H., Kitakata, H., Mitani, F., Fukuda, K., Goda, N., Ichihara, A. & Sano, M., 2020 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Open Access

Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia conducted in Japan during the past quarter century

Yanada, M., Takami, A., Yamasaki, S., Arai, Y., Konuma, T., Uchida, N., Najima, Y., Fukuda, T., Tanaka, M., Ozawa, Y., Ikegame, K., Takanashi, M., Ichinohe, T., Okamoto, S., Atsuta, Y. & Yano, S., 2020 Jun 1, In : Annals of Hematology. 99, 6, p. 1351-1360 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Allogeneic hematopoietic cell transplantation in patients with untreated acute myeloid leukemia: a KSGCT multicenter retrospective analysis

on behalf of the Kanto Study Group for Cell Therapy (KSGCT), 2020 Jul 1, In : Bone Marrow Transplantation. 55, 7, p. 1497-1501 5 p.

Research output: Contribution to journalLetter

Allogeneic Hematopoietic Stem Cell Transplantation for Post-essential Thrombocythemia and Post-polycythemia Vera Myelofibrosis

Murata, M., Suzuki, R., Nishida, T., Shirane, S., Shimazu, Y., Minami, Y., Mori, T., Doki, N., Kanda, Y., Uchida, N., Tanaka, M., Ishikawa, J., Togitani, K., Fukuda, T., Ichinohe, T., Atsuta, Y., Nagamura-Inoue, T. & Kiyoi, H., 2020, In : Internal medicine (Tokyo, Japan). 59, 16, p. 1947-1956 10 p.

Research output: Contribution to journalArticle

Open Access

A miRNA-based diagnostic model predicts resectable lung cancer in humans with high accuracy

Asakura, K., Kadota, T., Matsuzaki, J., Yoshida, Y., Yamamoto, Y., Nakagawa, K., Takizawa, S., Aoki, Y., Nakamura, E., Miura, J., Sakamoto, H., Kato, K., Watanabe, S. I. & Ochiya, T., 2020 Dec 1, In : Communications biology. 3, 1, 134.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
2 Citations (Scopus)

An official JRS statement: The principles of fractional exhaled nitric oxide (FeNO) measurement and interpretation of the results in clinical practice

Japanese Respiratory Society Assembly on Pulmonary Physiology, 2020, (Accepted/In press) In : Respiratory Investigation.

Research output: Contribution to journalReview article

A novel technique to avoid perforation of the right ventricle by the temporary pacing lead during transcatheter aortic valve implantation

Tanaka, M., Yanagisawa, R., Yashima, F., Arai, T., Watanabe, Y., Naganuma, T., Shirai, S., Araki, M., Tada, N., Yamanaka, F., Shimizu, H., Fukuda, K., Yamamoto, M. & Hayashida, K., 2020, (Accepted/In press) In : Cardiovascular Intervention and Therapeutics.

Research output: Contribution to journalArticle

Antigen-driven selection of antibodies against SSA, SSB and the centromere complex', including a novel antigen, MIS12 complex, in human salivary glands

Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., Kato, S., Tsunoda, K., Arase, H. & Takeuchi, T., 2020 Jan 1, In : Annals of the rheumatic diseases. 79, 1, p. 150-158 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn's disease in Japanese and Korean patients: The OPERA study

Saruta, M., Park, D. I., Kim, Y. H., Yang, S. K., Jang, B. I., Cheon, J. H., Im, J. P., Kanai, T., Katsuno, T., Ishiguro, Y., Nagaoka, M., Isogawa, N., Li, Y., Banerjee, A., Ahmad, A., Hassan-Zahraee, M., Clare, R., Gorelick, K. J., Cataldi, F., Watanabe, M. & 1 others, Hibi, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

Open Access

Anti-RNP antibodies delineate a subgroup of myositis: A systematic retrospective study on 46 patients

Wesner, N., Uruha, A., Suzuki, S., Mariampillai, K., Granger, B., Champtiaux, N., Rigolet, A., Schoindre, Y., Lejeune, S., Guillaume-Jugnot, P., Vautier, M., Hervier, B., Simon, A., Granier, F., Gallay, L., Nishino, I., Benveniste, O. & Allenbach, Y., 2020 Mar, In : Autoimmunity Reviews. 19, 3, 102465.

Research output: Contribution to journalLetter

Antisynthetase myopathy

Suzuki, S., 2020, In : Clinical Neurology. 60, 3, p. 175-180 6 p.

Research output: Contribution to journalArticle

Open Access

Anti-TSLP antibodies: Targeting a master regulator of type 2 immune responses

Nakajima, S., Kabata, H., Kabashima, K. & Asano, K., 2020 Apr, In : Allergology International. 69, 2, p. 197-203 7 p.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)

A paradigm shift in the treatment of type 2 diabetes and heart failure

Sano, M., 2020, In : Journal of atherosclerosis and thrombosis. 27, 8, p. 727-731 5 p.

Research output: Contribution to journalArticle

Open Access

A phase 3 study of nivolumab in previously treated advanced gastric or gastroesophageal junction cancer (ATTRACTION-2): 2-year update data

Chen, L. T., Satoh, T., Ryu, M. H., Chao, Y., Kato, K., Chung, H. C., Chen, J. S., Muro, K., Kang, W. K., Yeh, K. H., Yoshikawa, T., Oh, S. C., Bai, L. Y., Tamura, T., Lee, K. W., Hamamoto, Y., Kim, J. G., Chin, K., Oh, D. Y., Minashi, K. & 5 others, Cho, J. Y., Tsuda, M., Sameshima, H., Kang, Y. K. & Boku, N., 2020 May 1, In : Gastric Cancer. 23, 3, p. 510-519 10 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

A Phase II Study of Regorafenib With a Lower Starting Dose in Patients With Metastatic Colorectal Cancer: Exposure–Toxicity Analysis of Unbound Regorafenib and Its Active Metabolites (RESET Trial)

Suzuki, T., Sukawa, Y., Imamura, C., Masuishi, T., Satake, H., Kumekawa, Y., Funakoshi, S., Kotaka, M., Horie, Y., Kawai, S., Okuda, H., Terazawa, T., Kondoh, C., Kato, K., Yoshimura, K., Ishikawa, H., Hamamoto, Y., Boku, N., Takaishi, H. & Kanai, T., 2020 Mar, In : Clinical Colorectal Cancer. 19, 1, p. 13-21.e3

Research output: Contribution to journalArticle

Appropriateness of Transcatheter Aortic Valve Replacement: Insight from the OCEAN-TAVI Registry

Inohara, T., Vemulapalli, S., Kohsaka, S., Yashima, F., Watanabe, Y., Shirai, S., Tada, N., Araki, M., Naganuma, T., Yamanaka, F., Ueno, H., Tabata, M., Mizutani, K., Higashimori, A., Takagi, K., Yamamoto, M., Shimizu, H., Fukuda, K. & Hayashida, K., 2020, (Accepted/In press) In : Circulation: Cardiovascular Quality and Outcomes. e006146.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Appropriate timing for a biochemical evaluation after adrenalectomy for unilateral aldosterone-producing adenoma

Takamatsu, K., Takeda, T., Hattori, S., Tanaka, N., Morita, S., Matsumoto, K., Kosaka, T., Mizuno, R., Shinojima, T., Kikuchi, E., Asanuma, H., Kurihara, I., Itoh, H. & Oya, M., 2020 Jun 1, In : Clinical Endocrinology. 92, 6, p. 503-508 6 p.

Research output: Contribution to journalArticle

A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort

Ohwada, C., Sakaida, E., Igarashi, A., Kobayashi, T., Doki, N., Mori, T., Kato, J., Koda, Y., Kanamori, H., Tanaka, M., Tachibana, T., Fujisawa, S., Nakajima, Y., Numata, A., Toyosaki, M., Aoyama, Y., Onizuka, M., Hagihara, M., Koyama, S., Kanda, Y. & 9 others, Nakasone, H., Shimizu, H., Kato, S., Watanabe, R., Shono, K., Sakai, R., Saito, T., Nakaseko, C. & Okamoto, S., 2020 Jan, In : Biology of Blood and Marrow Transplantation. 26, 1, p. 162-170 9 p.

Research output: Contribution to journalArticle

A randomized controlled trial of a smoking cessation smartphone application with a carbon monoxide checker

Masaki, K., Tateno, H., Nomura, A., Muto, T., Suzuki, S., Satake, K., Hida, E. & Fukunaga, K., 2020 Dec 1, In : npj Digital Medicine. 3, 1, 35.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
Open Access
3 Citations (Scopus)

A significant association of non-obese non-alcoholic fatty liver disease with sarcopenic obesity

Kashiwagi, K., Takayama, M., Fukuhara, K., Shimizu-Hirota, R., Chu, P. S., Nakamoto, N., Inoue, N., Iwao, Y. & Kanai, T., 2020 Aug, In : Clinical Nutrition ESPEN. 38, p. 86-93 8 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Hayashi, K., Hishikawa, A., Hashiguchi, A., Azegami, T., Yoshimoto, N., Nakamichi, R., Tokuyama, H. & Itoh, H., 2020 Dec 1, In : Scientific reports. 10, 1, 237.

Research output: Contribution to journalArticle

Open Access

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: The Hisayama Study

Inaishi, J., Saisho, Y., Hirakawa, Y., Yoshida, D., Hata, J., Mukai, N., Watanabe, Y., Oda, Y., Itoh, H. & Ninomiya, T., 2020 Sep 1, In : Journal of Diabetes Investigation. 11, 5, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Association of radiographic findings in hand X-ray with clinical features and autoantibodies in patients with systemic sclerosis

Sakata, K., Kaneko, Y., Yasuoka, H. & Takeuchi, T., 2020 Jan 1, In : Clinical Rheumatology. 39, 1, p. 113-118 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association of Second-Generation Drug-Eluting Stent Length With 2-Year Adverse Clinical Outcomes Among Japanese Patients With Ischemic Heart Disease

Ejiri, K., Sawano, M., Numasawa, Y., Noma, S., Ito, H., Fukuda, K. & Kohsaka, S., 2020 Aug 3, In : JAMA network open. 3, 8, p. e2012546

Research output: Contribution to journalArticle

Open Access

Associations among liver disease, serum lipid profile, body mass index, ketonuria, meal skipping, and the alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 genotypes in Japanese men with alcohol dependence

Yokoyama, A., Taniki, N., Nakamoto, N., Tomita, K., Hara, S., Mizukami, T., Maruyama, K. & Yokoyama, T., 2020 May 1, In : Hepatology Research. 50, 5, p. 565-577 13 p.

Research output: Contribution to journalArticle

Open Access

Associations of birthweight and history of childhood obesity with beta cell mass in Japanese adults

Sasaki, H., Saisho, Y., Inaishi, J., Watanabe, Y., Tsuchiya, T., Makio, M., Sato, M., Kitago, M., Yamada, T. & Itoh, H., 2020 Jun 1, In : Diabetologia. 63, 6, p. 1199-1210 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages

Hirata, T., Arai, Y., Yuasa, S., Abe, Y., Takayama, M., Sasaki, T., Kunitomi, A., Inagaki, H., Endo, M., Morinaga, J., Yoshimura, K., Adachi, T., Oike, Y., Takebayashi, T., Okano, H. & Hirose, N., 2020 Dec 1, In : Nature communications. 11, 1, 3820.

Research output: Contribution to journalArticle

Open Access

Atrial Fibrillation-Associated Ischemic Stroke Patients with Prior Anticoagulation Have Higher Risk for Recurrent Stroke

Tanaka, K., Koga, M., Lee, K. J., Kim, B. J., Park, E. L., Lee, J., Mizoguchi, T., Yoshimura, S., Cha, J. K., Lee, B. C., Nakahara, J., Suzuki, N., Bae, H. J. & Toyoda, K., 2020 Apr 1, In : Stroke. p. 1150-1157 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus

Hanaoka, H., Nishimoto, T., Okazaki, Y., Takeuchi, T. & Kuwana, M., 2020 Apr 21, In : Arthritis Research and Therapy. 22, 1, 88.

Research output: Contribution to journalArticle

Open Access

Author Correction: De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies (Scientific Reports, (2017), 7, 1, (16871), 10.1038/s41598-017-17209-0)

Mitsuhashi, K., Ito, D., Mashima, K., Oyama, M., Takahashi, S. & Suzuki, N., 2020 Dec 1, In : Scientific reports. 10, 1, 8746.

Research output: Contribution to journalComment/debate

Open Access