Department of Internal Medicine

Research Output 1981 2019

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Review article
2019

Balloon Pulmonary Angioplasty (Percutaneous Transluminal Pulmonary Angioplasty) for Chronic Thromboembolic Pulmonary Hypertension: A Japanese Perspective

Kataoka, M., Inami, T., Kawakami, T., Fukuda, K. & Satoh, T., 2019 Jul 22, In : JACC: Cardiovascular Interventions. 12, 14, p. 1382-1388 7 p.

Research output: Contribution to journalReview article

Open Access
Balloon Angioplasty
Angioplasty
Pulmonary Hypertension
Lung
Therapeutics

Biventricular takotsubo cardiomyopathy with asymmetrical wall motion abnormality between left and right ventricle: a report of new case and literature review

Tsugu, T., Nagatomo, Y., Nakajima, Y., Kageyama, T., Endo, J., Itabashi, Y. & Kawakami, T., 2019 Sep 13, In : Journal of Echocardiography. 17, 3, p. 123-128 6 p.

Research output: Contribution to journalReview article

Takotsubo Cardiomyopathy
Heart Ventricles
Kinesis
Electrocardiography
Hong Kong
2 Citations (Scopus)

Capsule endoscopy for small-intestinal disorders: Current status

Hosoe, N., Takabayashi, K., Ogata, H. & Kanai, T., 2019 Jan 1, In : Digestive Endoscopy.

Research output: Contribution to journalReview article

Capsule Endoscopy
Reading
Crohn Disease
Endoscopy
Intestinal Polyps
2 Citations (Scopus)

Cardiorenal Protection: Potential of SGLT2 Inhibitors and GLP-1 Receptor Agonists in the Treatment of Type 2 Diabetes

Nagahisa, T. & Saisho, Y., 2019 Jan 1, (Accepted/In press) In : Diabetes Therapy.

Research output: Contribution to journalReview article

Sodium-Glucose Transport Proteins
Type 2 Diabetes Mellitus
Glucose
Cardiovascular Diseases
Metformin

Characteristics and prognosis of IgG4-related periaortitis/periarteritis: A systematic literature review

Akiyama, M., Kaneko, Y. & Takeuchi, T., 2019 Jan 1, In : Autoimmunity Reviews. 102354.

Research output: Contribution to journalReview article

Immunoglobulins
Arteritis
Aneurysm
Adrenal Cortex Hormones
Pathologic Constriction

Concise Review: Genetic and Epigenetic Regulation of Cardiac Differentiation from Human Pluripotent Stem Cells

Fujita, J., Tohyama, S., Kishino, Y., Okada, M. & Morita, Y., 2019 Jan 1, In : Stem Cells.

Research output: Contribution to journalReview article

Open Access
Pluripotent Stem Cells
Epigenomics
Cardiac Myocytes
Transcription Factors
Histone Code
3 Citations (Scopus)

Current new challenges in the management of ulcerative colitis

Fukuda, T., Naganuma, M. & Kanai, T., 2019 Jan 1, In : Intestinal Research. 17, 1, p. 36-44 9 p.

Research output: Contribution to journalReview article

Ulcerative Colitis
Immunosuppressive Agents
Antibodies
Adrenal Cortex Hormones
Therapeutics

Current state and future prospect of the therapeutic strategy targeting cysteinyl leukotriene metabolism in asthma

Yamamoto, T., Miyata, J., Arita, M., Fukunaga, K. & Kawana, A., 2019 Nov, In : Respiratory Investigation. 57, 6, p. 534-543 10 p.

Research output: Contribution to journalReview article

Asthma
Leukotriene E4
Cytokines
Leukotriene D4
Leukotriene Antagonists

Cysteinyl leukotriene metabolism of human eosinophils in allergic disease

Miyata, J., Fukunaga, K., Kawashima, Y., Ohara, O. & Arita, M., 2019 Jan 1, In : Allergology International.

Research output: Contribution to journalReview article

Open Access
Eosinophils
Fatty Acids
Cytokines
Leukotriene D4
Nasal Polyps

DNA Damage Repair and DNA Methylation in the Kidney

Hayashi, K., Hishikawa, A. & Itoh, H., 2019 Jan 1, In : American Journal of Nephrology.

Research output: Contribution to journalReview article

Open Access
DNA Methylation
DNA Repair
DNA Damage
Kidney
Podocytes

Electric endocut and autocut resection for endoscopic papillectomy: A systematic review

Minami, K., Iwasaki, E., Fukuhara, S., Horibe, M., Seino, T., Kawasaki, S., Katayama, T., Takimoto, Y., Tamagawa, H., MacHida, Y., Kanai, T. & Itoi, T., 2019 Jan 1, In : Internal Medicine. 58, 19, p. 2767-2772 6 p.

Research output: Contribution to journalReview article

Open Access
Pancreatitis
Incidence
Hemorrhage
PubMed
Libraries
1 Citation (Scopus)

Epigenetic regulation of T helper cells and intestinal pathogenicity

Hagihara, Y., Yoshimatsu, Y., Mikami, Y., Takada, Y., Mizuno, S. & Kanai, T., 2019 Jan 1, In : Seminars in Immunopathology.

Research output: Contribution to journalReview article

Helper-Inducer T-Lymphocytes
Inflammatory Bowel Diseases
Epigenomics
Virulence
Immune System
1 Citation (Scopus)

Features of and preventive measures against hypertension in the young

Kawabe, H., Azegami, T., Takeda, A., Kanda, T., Saito, I., Saruta, T. & Hirose, H., 2019 Jan 1, In : Hypertension Research.

Research output: Contribution to journalReview article

Open Access
Hypertension
Students
Blood Pressure
Obesity
Habits
1 Citation (Scopus)

Hypertension as a Metabolic Disorder and the Novel Role of the Gut

Tanaka, M. & Itoh, H., 2019 Aug 1, In : Current Hypertension Reports. 21, 8, 63.

Research output: Contribution to journalReview article

Open Access
Blood Pressure
Hypertension
Salts
Sodium
Sympathetic Nervous System
2 Citations (Scopus)

Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine

Akiyama, S., Matsuoka, K., Fukuda, K., Hamada, S., Shimizu, M., Nanki, K., Mizuno, S., Kiyohara, H., Arai, M., Sugimoto, S., Iwao, Y., Ogata, H., Hisamatsu, T., Naganuma, M., Motobayashi, M., Suzuki, K., Takenaka, K., Fujii, T., Saito, E., Nagahori, M. & 5 others, Ohtsuka, K., Mochizuki, M., Watanabe, M., Hashiguchi, M. & Kanai, T., 2019 Jan 1, In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalReview article

Inflammatory Bowel Diseases
Erythrocyte Indices
Leukopenia
Leukocyte Count
Genotype

Management of elderly ulcerative colitis in Japan

Higashiyama, M., Sugita, A., Koganei, K., Wanatabe, K., Yokoyama, Y., Uchino, M., Nagahori, M., Naganuma, M., Bamba, S., Kato, S., Takeuchi, K., Omori, T., Takagi, T., Matsumoto, S., Nagasaka, M., Sagami, S., Kitamura, K., Katsurada, T., Sugimoto, K., Takatsu, N. & 6 others, Saruta, M., Sakurai, T., Watanabe, K., Nakamura, S., Suzuki, Y. & Hokari, R., 2019 Jan 1, In : Journal of gastroenterology.

Research output: Contribution to journalReview article

Ulcerative Colitis
Japan
Comorbidity
Polypharmacy
Epidemiology
Open Access
Nicotinamide Mononucleotide
Sirtuin 1
Diabetic Nephropathies
NAD
Podocytes
3 Citations (Scopus)

Spreading depression as a preclinical model of migraine

Harriott, A. M., Takizawa, T., Chung, D. Y. & Chen, S. P., 2019 May 2, In : Journal of Headache and Pain. 20, 1, 45.

Research output: Contribution to journalReview article

Open Access
Migraine Disorders
Optogenetics
Neuroglia
Epilepsy
Theoretical Models
Open Access
Indigo Carmine
Immune System Diseases
Inflammatory Bowel Diseases
Therapeutics
Psoriasis
Open Access
Renin-Angiotensin System
Vaccines
Hypertension
Antihypertensive Agents
Medication Adherence

Worldwide Network for Blood and Marrow Transplantation (WBMT) perspective: the role of biosimilars in hematopoietic cell transplant: current opportunities and challenges in low- and lower-middle income countries

Muhsen, I. N., Hashmi, S. K., Niederweiser, D., Kroeger, N., Agrawal, S., Pasquini, M. C., Atsuta, Y., Ballen, K. K., Seber, A., Saber, W., Kharfan-Dabaja, M. A., Rasheed, W., Okamoto, S., Khera, N., Wood, W. A., Koh, M. B. C., Greinix, H., Kodera, Y., Szer, J., Horowitz, M. M. & 2 others, Weisdorf, D. & Aljurf, M., 2019 Jan 1, (Accepted/In press) In : Bone Marrow Transplantation.

Research output: Contribution to journalReview article

Biosimilar Pharmaceuticals
Transplantation
Bone Marrow
Transplants
Cell Transplantation
2018
2 Citations (Scopus)

Acute heart failure management in the USA and Japan: overview of practice patterns and review of evidence

Tanaka, T. D., Sawano, M., Ramani, R., Friedman, M. & Kosaka, S., 2018 Oct 1, In : ESC heart failure. 5, 5, p. 931-947 17 p.

Research output: Contribution to journalReview article

Japan
Heart Failure
Medical Manuscripts
Therapeutics
Public Health
29 Citations (Scopus)

A new class of drugs for heart failure: SGLT2 inhibitors reduce sympathetic overactivity

Sano, M., 2018 May 1, In : Journal of Cardiology. 71, 5, p. 471-476 6 p.

Research output: Contribution to journalReview article

Sodium-Glucose Transport Proteins
Heart Failure
Pharmaceutical Preparations
Type 2 Diabetes Mellitus
Kidney
3 Citations (Scopus)
Stomach Neoplasms
Neoplasms
Therapeutics
Immunotherapy
Japan
4 Citations (Scopus)

Clinical practice guideline for Sjögren’s syndrome 2017

Sumida, T., Azuma, N., Moriyama, M., Takahashi, H., Asashima, H., Honda, F., Abe, S., Ono, Y., Hirota, T., Hirata, S., Tanaka, Y., Shimizu, T., Nakamura, H., Kawakami, A., Sano, H., Ogawa, Y., Tsubota, K., Ryo, K., Saito, I., Tanaka, A. & 14 others, Nakamura, S., Takamura, E., Tanaka, M., Suzuki, K., Takeuchi, T., Yamakawa, N., Mimori, T., Ohta, A., Nishiyama, S., Yoshihara, T., Suzuki, Y., Kawano, M., Tomiita, M. & Tsuboi, H., 2018 May 4, In : Modern Rheumatology. 28, 3, p. 383-408 26 p.

Research output: Contribution to journalReview article

Practice Guidelines
Japan
Information Services
Information Dissemination
Rheumatology
10 Citations (Scopus)

CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) in 2018

The Task Force on Primary Percutaneous Coronary Intervention (PCI) of the Japanese Cardiovascular Interventional Therapeutics (CVIT), 2018 Apr 1, In : Cardiovascular Intervention and Therapeutics. 33, 2, p. 178-203 26 p.

Research output: Contribution to journalReview article

Percutaneous Coronary Intervention
Myocardial Infarction
Guidelines
Japan
Therapeutics
18 Citations (Scopus)

Follicular helper T cells in the pathogenesis of IgG4-related disease

Akiyama, M., Suzuki, K., Yasuoka, H., Kaneko, Y., Yamaoka, K. & Takeuchi, T., 2018 Feb 1, In : Rheumatology (United Kingdom). 57, 2, p. 236-245 10 p., kex171.

Research output: Contribution to journalReview article

Helper-Inducer T-Lymphocytes
Immunoglobulin G
Germinal Center
Plasma Cells
Immunoglobulin Class Switching

Immune checkpoint inhibitors and neuromuscular adverse events

Suzuki, S., 2018 Apr 1, In : Brain and Nerve. 70, 4, p. 461-466 6 p.

Research output: Contribution to journalReview article

Myositis
Dysgeusia
Therapeutics
Neoplasms
Polyneuropathies
1 Citation (Scopus)

Management of challenging immune-related gastrointestinal adverse events associated with immune checkpoint inhibitors

Hamamoto, Y., Shin, N., Hoshino, T. & Kanai, T., 2018 Dec 1, In : Future Oncology. 14, 30, p. 3187-3198 12 p.

Research output: Contribution to journalReview article

Gastroenterology
Immunosuppressive Agents
Endoscopy
Diarrhea
Referral and Consultation

Review of the small intestinal mucosal lesion

Hosoe, N., Ogata, H. & Kanai, T., 2018 Jan 1, In : Journal of Japanese Society of Gastroenterology. 115, 7, p. 605-611 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Temporal trends in renal function and birthweight in Japanese adolescent males (1998-2015)

Kanda, T., Takeda, A., Hirose, H., Abe, T., Urai, H., Inokuchi, M., Wakino, S., Tokumura, M., Itoh, H. & Kawabe, H., 2018 Feb 1, In : Nephrology Dialysis Transplantation. 33, 2, p. 304-310 7 p.

Research output: Contribution to journalReview article

Glomerular Filtration Rate
Kidney
Population
Chronic Renal Insufficiency
Proteinuria
15 Citations (Scopus)

The group 2 innate lymphoid cell (ILC2) regulatory network and its underlying mechanisms

Kabata, H., Moro, K. & Koyasu, S., 2018 Nov 1, In : Immunological Reviews. 286, 1, p. 37-52 16 p.

Research output: Contribution to journalReview article

Lymphocytes
Cytokines
Interleukin-27
Interleukin-9
Leukotriene E4
6 Citations (Scopus)

Transcription factors as therapeutic targets in chronic kidney disease

Hishikawa, A., Hayashi, K. & Itoh, H., 2018 Jan 1, In : Molecules. 23, 5, 1123.

Research output: Contribution to journalReview article

kidney diseases
Chronic Renal Insufficiency
Transcription Factors
Epigenomics
NF-E2 Transcription Factor

Treatment strategy for inflammatory bowel disease with a focus on biologicals

Fukuda, T., Naganuma, M. & Kanai, T., 2018 Jan 1, In : Journal of Japanese Society of Gastroenterology. 115, 3, p. 272-282 11 p.

Research output: Contribution to journalReview article

Inflammatory Bowel Diseases
5 Citations (Scopus)
Therapeutics
Patient Satisfaction
Surveys and Questionnaires
Patient Reported Outcome Measures
Sodium-Glucose Transport Proteins
2017
5 Citations (Scopus)

Clinical significance of cardiometabolic memory: A systematic review of randomized controlled trials

Itoh, H., Kurihara, I., Miyashita, K. & Tanaka, M., 2017 Jun 1, In : Hypertension Research. 40, 6, p. 526-534 9 p.

Research output: Contribution to journalReview article

Randomized Controlled Trials
Risk Reduction Behavior
Dyslipidemias
Blood Pressure
Hypertension
6 Citations (Scopus)

Effect of prophylactic clipping in colorectal endoscopic resection: A meta-analysis of randomized controlled studies

Nishizawa, T., Suzuki, H., Goto, O., Ogata, H., Kanai, T. & Yahagi, N., 2017 Oct 1, In : United European Gastroenterology Journal. 5, 6, p. 859-867 9 p.

Research output: Contribution to journalReview article

Meta-Analysis
Hemorrhage
Odds Ratio
Databases
PubMed
18 Citations (Scopus)
Cortical Spreading Depression
Microglia
Brain
Neurons
Yolk Sac
1 Citation (Scopus)

Hemoperitoneum secondary to rupture of a hepatic metastasis from small cell lung cancer during chemotherapy: A case with a literature review

Mochimaru, T., Minematsu, N., Ohsawa, K., Tomomatsu, K., Miura, H., Betsuyaku, T. & Murakami, M., 2017, In : Internal Medicine. 56, 6, p. 695-699 5 p.

Research output: Contribution to journalReview article

Hemoperitoneum
Small Cell Lung Carcinoma
Rupture
Neoplasm Metastasis
Drug Therapy
20 Citations (Scopus)

Integrated Diagnosis Project for Inflammatory Myopathies: An association between autoantibodies and muscle pathology

Suzuki, S., Uruha, A., Suzuki, N. & Nishino, I., 2017 Jul 1, In : Autoimmunity Reviews. 16, 7, p. 693-700 8 p.

Research output: Contribution to journalReview article

Myositis
Autoantibodies
Pathology
Dermatomyositis
Muscles

Intestinal immune response is regulated by gut microbe

Shun, T., Tomohisa, S. & Kanai, T., 2017 Jan 1, In : Japanese Journal of Clinical Immunology. 40, 6, p. 408-415 8 p.

Research output: Contribution to journalReview article

Microbiota
Dysbiosis
Homeostasis
Intestinal Diseases
Inflammatory Bowel Diseases
4 Citations (Scopus)

Manipulation of Pluripotent Stem Cell Metabolism for Clinical Application

Tohyama, S., Tanosaki, S., Someya, S., Fujita, J. & Fukuda, K., 2017 Mar 1, In : Current Stem Cell Reports. 3, 1, p. 28-34 7 p.

Research output: Contribution to journalReview article

Pluripotent Stem Cells
Metabolome
Costs and Cost Analysis
Preclinical Drug Evaluations
Cell Survival
2 Citations (Scopus)

New onset of myasthenia gravis after intravesical Bacillus Calmette-Guerin

Takizawa, T., Kojima, M., Suzuki, S., Osada, T., Kitagawa, S., Nakahara, J., Takahashi, S. & Suzuki, N., 2017 Nov 1, In : Medicine (United States). 96, 46, e8757.

Research output: Contribution to journalReview article

Myasthenia Gravis
Mycobacterium bovis
Methylprednisolone
Urinary Bladder Neoplasms
Pharmaceutical Preparations
4 Citations (Scopus)

Polymyositis with elevated serum IgG4 levels and abundant IgG4 + plasma cell infiltration

Anan, R., Akiyama, M., Kaneko, Y., Kikuchi, J., Suzuki, K., Matsubara, S. & Takeuchi, T., 2017 Dec 1, In : Medicine (United States). 96, 48, e8710.

Research output: Contribution to journalReview article

Polymyositis
Plasma Cells
Immunoglobulin G
Serum
Muscles

Questionnaire survey on the process of specialty training in neurology in Japan

Sonoo, M., Nishiyama, K., Ando, T., Shindo, K., Kanda, T., Aoki, M., Kamei, S., Kikuchi, S., Kusunoki, S., Suzuki, N., Sobue, G., Nakashima, K., Hara, H., Hirata, K., Mizusawa, H., Murai, H., Murata, M., Mochizuki, H., Takahashi, R. & Kira, J. I., 2017, In : Clinical Neurology. 57, 7, p. 402-410 9 p.

Research output: Contribution to journalReview article

Neurology
Japan
Internship and Residency
Urban Hospitals
Documentation
2 Citations (Scopus)

Remyelination in multiple sclerosis: Pathology and treatment strategies

Nakahara, J., 2017 Jan 1, In : Clinical and Experimental Neuroimmunology. 8, p. 40-46 7 p.

Research output: Contribution to journalReview article

Multiple Sclerosis
Pathology
Demyelinating Diseases
Myelin Sheath
Therapeutics

Research and development of therapy for advanced heart failure by utilizing pluripotent stem cell-derived cardiomyocytes

Tanosaki, S., Tohyama, S. & Fukuda, K., 2017, In : Folia Pharmacologica Japonica. 150, 5, p. 246-250 5 p.

Research output: Contribution to journalReview article

Pluripotent Stem Cells
Cardiac Myocytes
Heart Failure
Research
Therapeutics
5 Citations (Scopus)

Targeted antibody therapy and relevant novel biomarkers for precision medicine for rheumatoid arthritis

Kaneko, Y. & Takeuchi, T., 2017 Nov 1, In : International Immunology. 29, 11, p. 511-517 7 p.

Research output: Contribution to journalReview article

Precision Medicine
Rheumatoid Arthritis
Biomarkers
Antibodies
Monoclonal Antibodies
2016
1 Citation (Scopus)

Bone turnover and bone structure in clinical animal models of COPD

Sasaki, M. & Chubachi, S., 2016 Jan 1, In : Clinical calcium. 26, 10, p. 1413-1418 6 p.

Research output: Contribution to journalReview article

Bone Remodeling
Emphysema
Chronic Obstructive Pulmonary Disease
Animal Models
Osteoporosis

Comment on: Expandable cardiovascular progenitor cells reprogrammed from fibroblasts

Yamakawa, H. & Fukuda, K., 2016, In : Stem Cell Investigation. 2016, DEC, 89.

Research output: Contribution to journalReview article

Stem Cells
Fibroblasts