Research Output

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Review article
2020

Advances in the diagnosis and treatment of dry eye

Kojima, T., Dogru, M., Kawashima, M., Nakamura, S. & Tsubota, K., 2020 Jan 1, (Accepted/In press) In : Progress in Retinal and Eye Research. 100842.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

A review on the epidemiology of myopia in school children worldwide

Grzybowski, A., Kanclerz, P., Tsubota, K., Lanca, C. & Saw, S. M., 2020 Jan 14, In : BMC ophthalmology. 20, 1, 1 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
2019

A novel and innovative paper-based analytical device for assessing tear lactoferrin of dry eye patients

Sonobe, H., Ogawa, Y., Yamada, K., Shimizu, E., Uchino, Y., Kamoi, M., Saijo, Y., Yamane, M., Citterio, D., Suzuki, K. & Tsubota, K., 2019 Jan, In : Ocular Surface. 17, 1, p. 160-166 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Clinical Factors for Rapid Endothelial Cell Loss After Corneal Transplantation: Novel Findings From the Aqueous Humor

Yazu, H., Yamaguchi, T., Tsubota, K. & Shimazaki, J., 2019 Jun 15, In : Current Ophthalmology Reports. 7, 2, p. 89-97 9 p.

Research output: Contribution to journalReview article

Review: Corneal endothelial cell derivation methods from ES/iPS cells

Hatou, S. & Shimmura, S., 2019 Oct 3, In : Inflammation and Regeneration. 39, 1, 19.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Survey of the effects of internet usage on the happiness of Japanese university students

Kitazawa, M., Yoshimura, M., Hitokoto, H., Sato-Fujimoto, Y., Murata, M., Negishi, K., Mimura, M., Tsubota, K. & Kishimoto, T., 2019 Oct 11, In : Health and Quality of Life Outcomes. 17, 1, 151.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)
2018

Clinical practice guideline for Sjögren’s syndrome 2017

Sumida, T., Azuma, N., Moriyama, M., Takahashi, H., Asashima, H., Honda, F., Abe, S., Ono, Y., Hirota, T., Hirata, S., Tanaka, Y., Shimizu, T., Nakamura, H., Kawakami, A., Sano, H., Ogawa, Y., Tsubota, K., Ryo, K., Saito, I., Tanaka, A. & 14 others, Nakamura, S., Takamura, E., Tanaka, M., Suzuki, K., Takeuchi, T., Yamakawa, N., Mimori, T., Ohta, A., Nishiyama, S., Yoshihara, T., Suzuki, Y., Kawano, M., Tomiita, M. & Tsuboi, H., 2018 May 4, In : Modern rheumatology. 28, 3, p. 383-408 26 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Current management and treatment of dry eye disease

Şimşek, C., Doğru, M., Kojima, T. & Tsubota, K., 2018 Dec 1, In : Turkish Journal of Ophthalmology. 48, 6, p. 309-313 5 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Interferons and dry eye in sjögren’s syndrome

Ogawa, Y., Shimizu, E. & Tsubota, K., 2018 Nov 10, In : International journal of molecular sciences. 19, 11, 3548.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Progress and Control of Myopia by Light Environments

Jiang, X., Kurihara, T., Torii, H. & Tsubota, K., 2018 Sep 1, In : Eye & contact lens. 44, 5, p. 273-278 6 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Roles of hypoxia response in retinal development and pathophysiology

Kurihara, T., 2018 Jan 1, In : Keio Journal of Medicine. 67, 1, p. 1-9 9 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)
2017

A multicenter retrospective survey of refractive surgery in 78,248 eyes

Kamiya, K., Igarashi, A., Hayashi, K., Negishi, K., Sato, M. & Bissen-Miyajima, H., 2017 Sep 1, In : Journal of Refractive Surgery. 33, 9, p. 598-602 5 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

New Perspectives on Dry Eye Definition and Diagnosis: A Consensus Report by the Asia Dry Eye Society

Tsubota, K., Yokoi, N., Shimazaki, J., Watanabe, H., Dogru, M., Yamada, M., Kinoshita, S., Kim, H. M., Tchah, H. W., Hyon, J. Y., Yoon, K. C., Seo, K. Y., Sun, X., Chen, W., Liang, L., Li, M., Liu, Z., Liu, Z., Sun, X., Chen, W. & 45 others, Deng, Y., Hong, J., Jie, Y., Li, M., Li, Y., Liang, L., Qi, H., Wang, H., Yan, X., Yang, W., Ye, Y., Yuan, J., Zhang, H., Zhan, H., Zhang, M., Zhao, S., Kim, H. M., Tchah, H., Choi, C. Y., Chung, E. S., Hyon, J. Y., Kim, H. S., Kim, M. K., Myoung-Joon, Kim, T. I., Lee, D. H., Lee, H. K., Seo, K. Y., Song, J. S., Yoon, K. C., Tsubota, K., Yokoi, N., Amano, S., Arita, R., Dogru, M., Hori, Y., Kawakita, T., Kawashima, M., Koh, S., Nishida, K., Ogawa, Y., Shimazaki, J., Watanabe, H., Yamada, M. & Yamaguchi, M., 2017 Jan 1, In : Ocular Surface. 15, 1, p. 65-76 12 p.

Research output: Contribution to journalReview article

142 Citations (Scopus)

TFOS DEWS II Definition and Classification Report

Craig, J. P., Nichols, K. K., Akpek, E. K., Caffery, B., Dua, H. S., Joo, C. K., Liu, Z., Nelson, J. D., Nichols, J. J., Tsubota, K. & Stapleton, F., 2017 Jul, In : Ocular Surface. 15, 3, p. 276-283 8 p.

Research output: Contribution to journalReview article

466 Citations (Scopus)

TFOS DEWS II Introduction

Nelson, J. D., Craig, J. P., Akpek, E. K., Azar, D. T., Belmonte, C., Bron, A. J., Clayton, J. A., Dogru, M., Dua, H. S., Foulks, G. N., Gomes, J. A. P., Hammitt, K. M., Holopainen, J., Jones, L., Joo, C. K., Liu, Z., Nichols, J. J., Nichols, K. K., Novack, G. D., Sangwan, V. & 6 others, Stapleton, F., Tomlinson, A., Tsubota, K., Willcox, M. D. P., Wolffsohn, J. S. & Sullivan, D. A., 2017 Jul, In : Ocular Surface. 15, 3, p. 269-275 7 p.

Research output: Contribution to journalReview article

51 Citations (Scopus)

TFOS DEWS II pathophysiology report

Bron, A. J., de Paiva, C. S., Chauhan, S. K., Bonini, S., Gabison, E. E., Jain, S., Knop, E., Markoulli, M., Ogawa, Y., Perez, V., Uchino, Y., Yokoi, N., Zoukhri, D. & Sullivan, D. A., 2017 Jul, In : Ocular Surface. 15, 3, p. 438-510 73 p.

Research output: Contribution to journalReview article

257 Citations (Scopus)
2016

Visual outcomes after LASIK using topography-guided vs wavefront-guided customized ablation systems

Toda, I., Ide, T., Fukumoto, T. & Tsubota, K., 2016 Nov 1, In : Journal of Refractive Surgery. 32, 11, p. 727-732 6 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)
2013

Changing trends in the treatment of dry-eye disease

Dogru, M., Nakamura, M., Shimazaki, J. & Tsubota, K., 2013 Dec 1, In : Expert Opinion on Investigational Drugs. 22, 12, p. 1581-1601 21 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)
2012

A novel clinical entity, IgG4-relateddisease (IgG4RD): General concept and details

Umehara, H., Okazaki, K., Masaki, Y., Kawano, M., Yamamoto, M., Saeki, T., Matsui, S., Sumida, T., Mimori, T., Tanaka, Y., Tsubota, K., Yoshino, T., Kawa, S., Suzuki, R., Takegami, T., Tomosugi, N., Kurose, N., Ishigaki, Y., Azumi, A., Kojima, M. & 38 others, Nakamura, S., Inoue, D., Fujikawa, K., Hamano, H., Kubo, K., Yamamoto, H., Hirokawa, M., Itoh, K., Kamisawa, T., Kawabata, D., Matsumoto, M., Minamoto, S., Murayama, K., Nishiyama, S., Ogawa, Y., Origuchi, T., Oyama, N., Sato, Y., Seto, M., Sugai, S., Tsukamoto, N., Takahira, M., Takahashi, H., Tsuboi, H., Waseda, Y., Kitagawa, K., Nojima, T., Yokoyama, H., Tonami, H., Fukushima, T., Tanaka, M., Fujita, Y., Sawaki, T., Kawanami, T., Miki, M., Iwao, H., Nakajima, A. & Nakamura, T., 2012 Feb, In : Modern rheumatology. 22, 1, p. 1-14 14 p.

Research output: Contribution to journalReview article

519 Citations (Scopus)

Neuroprotective effects of lutein in the retina

Ozawa, Y., Sasaki, M., Takahashi, N., Kamoshita, M., Miyake, S. & Tsubota, K., 2012 Jan 1, In : Current Pharmaceutical Design. 18, 1, p. 51-56 6 p.

Research output: Contribution to journalReview article

90 Citations (Scopus)

Renin-angiotensin system hyperactivation can induce inflammation and retinal neural dysfunction

Kurihara, T., Ozawa, Y., Ishida, S., Okano, H. & Tsubota, K., 2012, In : International Journal of Inflammation. 2012, 581695.

Research output: Contribution to journalReview article

28 Citations (Scopus)

The Vision van, a mobile eye clinic, Aids relief Efforts in Tsunami-Stricken areas

Oshima, C. R., Yuki, K., Uchida, A., Dogru, M., Koto, T., Ozawa, Y. & Tsubota, K., 2012 Mar 1, In : Keio Journal of Medicine. 61, 1, p. 10-14 5 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2011

[Improvement in the method of cultivated corneal epithelial sheet generation].

Kawakita, T., 2011 Nov, In : Nihon Ganka Gakkai zasshi. 115, 11, p. 1007-1014 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Neural degeneration in the retina of the streptozotocin-induced type 1 diabetes model

Ozawa, Y., Kurihara, T., Sasaki, M., Ban, N., Yuki, K., Kubota, S. & Tsubota, K., 2011 Dec 1, In : Experimental Diabetes Research. 2011, 108328.

Research output: Contribution to journalReview article

52 Citations (Scopus)

Pharmacotherapy of dry eye

Dogru, M. & Tsubota, K., 2011 Feb 1, In : Expert Opinion on Pharmacotherapy. 12, 3, p. 325-334 10 p.

Research output: Contribution to journalReview article

50 Citations (Scopus)

Review of diagnosis and clinical course of retinoblastoma

Nozaki, M., Kase, S., Yoshida, K., Ishijima, K., Noda, M., Suzuki, S., Azuma, N. & Ishida, S., 2011 Jul 15, In : Japanese Journal of Clinical Ophthalmology. 65, 7, p. 1123-1127 5 p.

Research output: Contribution to journalReview article

2010

Pattern-reversal visual-evoked potential in patients with occult macular dystrophy

Hanazono, G., Ohde, H., Shinoda, K., Tsunoda, K., Tsubota, K. & Miyake, Y., 2010, In : Clinical Ophthalmology. 4, 1, p. 1515-1520 6 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Retinal aging and sirtuins

Ozawa, Y., Kubota, S., Narimatsu, T., Yuki, K., Koto, T., Sasaki, M. & Tsubota, K., 2010 Sep 1, In : Ophthalmic research. 44, 3, p. 199-203 5 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

The era of antiaging ophthalmology comes of age: Antiaging approach for dry eye treatment

Tsubota, K., Kawashima, M., Inaba, T., Dogru, M., Ogawa, Y., Nakamura, S., Shinmura, K., Higuchi, A. & Kawakita, T., 2010 Sep 1, In : Ophthalmic research. 44, 3, p. 146-154 9 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)
2008

Pathologic roles of prorenin and (pro)renin receptor in the eye

Satofuka, S., Ichihara, A., Nagai, N., Tsubota, K., Itoh, H. & Ishida, S., 2008 May 2, In : Frontiers in Bioscience. 13, 10, p. 3884-3895 12 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2007

Oxidative stress and inflammation: hypothesis for the mechanism of aging

Tsubota, K., 2007 Mar, In : Nippon Ganka Gakkai zasshi. 111, 3, p. 193-205; discussion 206

Research output: Contribution to journalReview article

19 Citations (Scopus)
2006

Deep anterior lamellar keratoplasty

Shimmura, S. & Tsubota, K., 2006 Aug 1, In : Current Opinion in Ophthalmology. 17, 4, p. 349-355 7 p.

Research output: Contribution to journalReview article

106 Citations (Scopus)

Laboratory findings in tear fluid analysis

Ohashi, Y., Dogru, M. & Tsubota, K., 2006 Jul 15, In : Clinica Chimica Acta. 369, 1, p. 17-28 12 p.

Research output: Contribution to journalReview article

132 Citations (Scopus)
2005

Ocular surface findings in Hallopeau-Siemens subtype of dystrophic epidermolysis bullosa: Report of a case and literature review

Matsumoto, Y., Dogru, M. & Tsubota, K., 2005 May 1, In : Cornea. 24, 4, p. 474-479 6 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Recording oculoplastic findings

Noda, M., 2005 Jun 1, In : Japanese Journal of Clinical Ophthalmology. 59, 6, p. 808-812 5 p.

Research output: Contribution to journalReview article

Successful topical application of a new antifungal agent, micafungin, in the treatment of refractory fungal corneal ulcers: Report of three cases and literature review

Matsumoto, Y., Dogru, M., Goto, E., Fujishima, H. & Tsubota, K., 2005 Aug 1, In : Cornea. 24, 6, p. 748-753 6 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)
2004

Clinical characteristics of conjunctivochalasis with or without aqueous tear deficiency

Tseng, S. C. G., Di Pascuale, M. A., Espana, E. M. & Kawakita, T., 2004 Mar, In : British Journal of Ophthalmology. 88, 3, p. 388-392 5 p.

Research output: Contribution to journalReview article

103 Citations (Scopus)

New insights into the diagnosis and treatment of dry eye

Dogru, M. & Tsubota, K., 2004 Apr, In : Ocular Surface. 2, 2, p. 59-75 17 p.

Research output: Contribution to journalReview article

38 Citations (Scopus)

Revised Japanese criteria for Sjögren's syndrome (1999): Availability and validity

Fujibayashi, T., Sugai, S., Miyasaka, N., Hayashi, Y. & Tsubota, K., 2004 Dec 1, In : Modern rheumatology. 14, 6, p. 425-434 10 p.

Research output: Contribution to journalReview article

177 Citations (Scopus)
2003

Surgical treatment of choroidal hemorrhage

Chen, C. J., Shinoda, H., Eshita, T., Kitamura, S., Shinoda, K. & Inoue, M., 2003 Dec 1, In : Japanese Journal of Clinical Ophthalmology. 57, 13, p. 1803-1807 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)