Department of Dentistry and Oral Surgery

Research Output 1988 2019

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Article
2006
36 Citations (Scopus)

Synergistic pathogenic effects of combined mouse monoclonal anti-desmoglein 3 IgG antibodies on pemphigus vulgaris blister formation

Kawasaki, H., Tsunoda, K., Hata, T., Ishii, K., Yamada, T. & Amagai, M., 2006 Dec, In : Journal of Investigative Dermatology. 126, 12, p. 2621-2630 10 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Blister
Immunoglobulin G
Antibodies
7 Citations (Scopus)

The efficacy of povidone-iodine products against periodontopathic bacteria

Nakagawa, T., Hosaka, Y., Ishihara, K., Hiraishi, T., Sato, S., Ogawa, T. & Kamoi, K., 2006 Feb, In : Dermatology. 212, SUPPL. 1, p. 109-111 3 p.

Research output: Contribution to journalArticle

Povidone-Iodine
Bacteria
Streptococcus anginosus
Prevotella intermedia
Fusobacterium nucleatum
42 Citations (Scopus)

Tolerance induction by the blockade of CD40/CD154 interaction in pemphigus vulgaris mouse model

Aoki-Ota, M., Kinoshita, M., Ota, T., Tsunoda, K., Iwasaki, T., Tanaka, S., Koyasu, S., Nishikawa, T. & Amagai, M., 2006 Jan, In : Journal of Investigative Dermatology. 126, 1, p. 105-113 9 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Immunoglobulin G
Monoclonal Antibodies
Adoptive Transfer
2005
150 Citations (Scopus)

Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display

Payne, A. S., Ishii, K., Kacir, S., Lin, C., Li, H., Hanakawa, Y., Tsunoda, K., Amagai, M., Stanley, J. R. & Siegel, D. L., 2005 Apr, In : Journal of Clinical Investigation. 115, 4, p. 888-899 12 p.

Research output: Contribution to journalArticle

Pemphigus
Autoantibodies
Bacteriophages
Desmoglein 3
Antibodies
18 Citations (Scopus)

In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line

Shimizu, A., Ishiko, A., Ota, T., Saito, H., Oka, H., Tsunoda, K., Amagai, M. & Nishikawa, T., 2005 May, In : Journal of Investigative Dermatology. 124, 5, p. 984-989 6 p.

Research output: Contribution to journalArticle

Desmoglein 3
Desmosomes
Cadherins
Adhesives
Desmogleins
2004
39 Citations (Scopus)

A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice

Aoki-Ota, M., Tsunoda, K., Ota, T., Iwasaki, T., Koyasu, S., Amagai, M. & Nishikawa, T., 2004 Aug, In : British Journal of Dermatology. 151, 2, p. 346-354 9 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Adoptive Transfer
Knockout Mice
Immunoglobulin G
10 Citations (Scopus)

Auto-reactive B cells against peripheral antigen, desmoglein 3, escape from tolerance mechanism

Ota, T., Aoki-Ota, M., Tsunoda, K., Simoda, K., Nishikawa, T., Amagai, M. & Koyasu, S., 2004 Oct, In : International Immunology. 16, 10, p. 1487-1495 9 p.

Research output: Contribution to journalArticle

Desmoglein 3
B-Lymphocytes
Antigens
Immunoglobulin M
Pemphigus
72 Citations (Scopus)

IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model

Shimizu, A., Ishiko, A., Ota, T., Tsunoda, K., Amagai, M. & Nishikawa, T., 2004 May, In : Journal of Investigative Dermatology. 122, 5, p. 1145-1153 9 p.

Research output: Contribution to journalArticle

Desmoglein 3
Desmosomes
Pemphigus
Keratins
Immunoglobulin G
2003
15 Citations (Scopus)

Gingipains as candidate antigens for Porphyromonas gingivalis vaccine

Nakagawa, T., Saito, A., Hosaka, Y. & Ishihara, K., 2003 Sep, In : Keio Journal of Medicine. 52, 3, p. 158-162 5 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Vaccines
Antigens
Periodontitis
Periodontal Diseases
220 Citations (Scopus)

Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 31

Tsunoda, K., Ota, T., Aoki, M., Yamada, T., Nagai, T., Nakagawa, T., Koyasu, S., Nishikawa, T. & Amagai, M., 2003 Feb 15, In : Journal of Immunology. 170, 4, p. 2170-2178 9 p.

Research output: Contribution to journalArticle

Desmogleins
Pemphigus
Adhesives
Monoclonal Antibodies
Phenotype
18 Citations (Scopus)

Relationship between transmission of Porphyromonas gingivalis and FimA type in spouses

Asano, H., Ishihara, K., Nakagawa, T., Yamada, S. & Okuda, K., 2003 Sep, In : Journal of Periodontology. 74, 9, p. 1355-1360 6 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Spouses
Periodontitis
Pulsed Field Gel Electrophoresis
Chronic Periodontitis
14 Citations (Scopus)

Suppression of the immune response against exogenous desmoglein 3 in desmoglein 3 knockout mice: An implication for gene therapy

Ohyama, M., Ota, T., Aoki, M., Tsunoda, K., Harada, R., Koyasu, S., Nishikawa, T. & Amagai, M., 2003 Apr 1, In : Journal of Investigative Dermatology. 120, 4, p. 610-615 6 p.

Research output: Contribution to journalArticle

Desmoglein 3
Gene therapy
Knockout Mice
Genetic Therapy
Immunoglobulin G
2002
35 Citations (Scopus)

Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris

Ohyama, M., Amagai, M., Tsunoda, K., Ota, T., Koyasu, S., Hata, J. I., Umezawa, A. & Nishikawa, T., 2002, In : Journal of Investigative Dermatology. 118, 1, p. 199-204 6 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Immunoglobulin G
Skin
Desmoglein 1
66 Citations (Scopus)

Pathogenic autoantibody production requires loss of tolerance against desmoglein 3 in both T and B cells in experimental pemphigus vulgaris

Tsunoda, K., Ota, T., Suzuki, H., Ohyama, M., Nagai, T., Nishikawa, T., Amagai, M. & Koyasu, S., 2002, In : European Journal of Immunology. 32, 3, p. 627-633 7 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Autoantibodies
B-Lymphocytes
T-Lymphocytes
19 Citations (Scopus)

Ultrastructural changes in mice actively producing antibodies to desmoglein 3 parallel those in patients with pemphigus vulgaris

Shimizu, A., Ishiko, A., Ota, T., Tsunoda, K., Koyasu, S., Amagai, M. & Nishikawa, T., 2002, In : Archives of Dermatological Research. 294, 7, p. 318-323 6 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Antibodies
Cadherins
Blister
2000
21 Citations (Scopus)

Production of the entire extracellular domain of BP180 (type XVII collagen) by baculovirus expression

Hata, Y., Fujii, Y., Tsunoda, K. & Amagai, M., 2000 Aug, In : Journal of Dermatological Science. 23, 3, p. 183-190 8 p.

Research output: Contribution to journalArticle

Bullous Pemphigoid
Baculoviridae
Epitopes
Antigens
Serum
204 Citations (Scopus)

Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus

Amagai, M., Tsunoda, K., Suzuki, H., Nishifuji, K., Koyasu, S. & Nishikawa, T., 2000 Mar, In : Journal of Clinical Investigation. 105, 5, p. 625-631 7 p.

Research output: Contribution to journalArticle

Desmoglein 3
Pemphigus
Autoantigens
Knockout Mice
Autoimmune Diseases
1999
332 Citations (Scopus)

The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile

Amagai, M., Tsunoda, K., Zillikens, D., Nagai, T. & Nishikawa, T., 1999, In : Journal of the American Academy of Dermatology. 40, 2 I, p. 167-170 4 p.

Research output: Contribution to journalArticle

Desmogleins
Pemphigus
Autoantibodies
Phenotype
Desmoglein 3
1997

Clinical application of gargle containing ELASE® to stomatitis due to radiation theraphy/anticances agent administration

Takamori, K., Asanami, S., Yokota, J., Kumagai, A., Tunoda, K., Okada, M., Kizu, H., Shiba, H. & Okada, Y., 1997, In : Oral Therapeutics and Pharmacology. 16, 3, p. 99-103 5 p.

Research output: Contribution to journalArticle

Stomatitis
Radiotherapy
Radiation
Mouth Neoplasms
Pain

Clinical effects of arbekacin on MRSA infections after oral and maxillofacial surgery

Onizawa, K., Uchiyama, K., Iwabuchi, H., Tsunoda, K., Okada, Y. & Asanami, S., 1997, In : Oral Therapeutics and Pharmacology. 16, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

Oral Surgery
Methicillin-Resistant Staphylococcus aureus
Intravenous Infusions
Infection
habekacin
1993
15 Citations (Scopus)

Clinical applications and basic studies of laser in dentistry and oral surgery.

Nanami, T., Shiba, H., Ikeuchi, S., Nagai, T., Asanami, S. & Shibata, T., 1993 Dec, In : Keio Journal of Medicine. 42, 4, p. 199-201 3 p.

Research output: Contribution to journalArticle

Oral Surgery
Dentistry
Lasers
Dentin
Mouth Diseases
9 Citations (Scopus)

The activatory effect of low incident energy He-Ne laser radiation on hydroxyapatite implants in rabbit mandibular bone

Asanami, S., Shiba, H., Ohtaishi, M., Okada, Y., Ohsaka, F. & Tanaka, Y., 1993, In : Laser Therapy. 5, 1, p. 29-32 4 p.

Research output: Contribution to journalArticle

Durapatite
Laser radiation
Hydroxyapatite
Bone
Lasers
1991
2 Citations (Scopus)

Adenocarcinoma of the sublingual gland.

Uchiyama, K., Ikeuchi, S., Shiba, H., Okada, Y. & Asanami, S., 1991 Mar, In : Keio Journal of Medicine. 40, 1, p. 20-24 5 p.

Research output: Contribution to journalArticle

Sublingual Gland
Adenocarcinoma
Neoplasm Metastasis
Mouth Floor
Dissection
1988
4 Citations (Scopus)

Studies of the clinical usefulness of porous hydroxylapatite in the field of dental and oral surgery.

Asanami, S., Koike, O., Chikata, M., Shiba, H., Ikeuchi, S., Okada, Y., Ohsaka, F. & Nomoto, T., 1988 Sep, In : Keio Journal of Medicine. 37, 3, p. 265-281 17 p.

Research output: Contribution to journalArticle