Department of Pharmacokinetics and Pharmacodynamics

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Pharmacokinetics Medicine & Life Sciences
oxaliplatin Medicine & Life Sciences
docetaxel Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
P-Glycoprotein Medicine & Life Sciences
Genotype Medicine & Life Sciences
Population Medicine & Life Sciences

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Research Output 1998 2018

Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype-Guided Dosing of Tamoxifen

Nakamura, T., Toshimoto, K., Lee, W., Imamura, C. K., Tanigawara, Y. & Sugiyama, Y., 2018 Jul 1, In : CPT: Pharmacometrics and Systems Pharmacology. 7, 7, p. 474-482 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Pharmacokinetics
Tamoxifen
Genotype
Predict
1 Citations

Dynamic changes in CD44v-positive cells after preoperative anti-HER2 therapy and its correlation with pathologic complete response in HER2-positive breast cancer

Yamauchi, T., Fernandez, J. R. E., Imamura, C., Yamauchi, H., Jinno, H., Takahashi, M., Kitagawa, Y., Nakamura, S., Lim, B., Krishnamurthy, S., Reuben, J. M., Liu, D., Tripathy, D., Chen, H., Takebe, N., Saya, H. & Ueno, N. T., 2018 Jan 1, In : Oncotarget. 9, 6, p. 6872-6882 11 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Epithelial-Mesenchymal Transition
Neoplastic Stem Cells
Therapeutics
Biomarkers

Individualized Dosing of Axitinib Based on First-Dose Area Under the Concentration–Time Curve for Metastatic Renal-Cell Carcinoma

Miura, Y., Imamura, C., Uchino, K., Kishida, T., Matsubara, N., Shinojima, T., Kondo, K., Hongo, F., Yoshimura, K., Tanigawara, Y. & Takano, T., 2018 Jan 1, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Disease-Free Survival
Survival Rate
Hand-Foot Syndrome
Confidence Intervals