Research Output 1992 2019

2019
Anastomotic Leak
Esophagectomy
Apgar Score
Survival
Esophageal Neoplasms
1 Citation (Scopus)

A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients

Tani, T., Naoki, K., Yasuda, H., Arai, D., Ishioka, K., Ohgino, K., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T. & Soejima, K., 2019 Jan 1, (Accepted/In press) In : Cancer Chemotherapy and Pharmacology.

Research output: Contribution to journalArticle

Chemotherapy
Non-Small Cell Lung Carcinoma
Cells
Drug Therapy
Mutation

Assessment of lymphatic flow based on the sentinel node concept in early gastric adenocarcinoma that satisfies expanded endoscopic resection criteria

Takeuchi, M., Kawakubo, H., Shimada, A., Matsuda, S., Nakahara, T., Mayanagi, S., Irino, T., Fukuda, K., Nakamura, R., Wada, N., Takeuchi, H. & Kitagawa, Y., 2019 Jan 1, (Accepted/In press) In : Gastric Cancer.

Research output: Contribution to journalArticle

Stomach
Adenocarcinoma
Neoplasm Metastasis
Stomach Neoplasms
cyhalothrin
1 Citation (Scopus)

A subanalysis of Japanese patients in a randomized, double-blind, placebo-controlled, phase 3 trial of nivolumab for patients with advanced gastric or gastro-esophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2)

Kato, K., Satoh, T., Muro, K., Yoshikawa, T., Tamura, T., Hamamoto, Y., Chin, K., Minashi, K., Tsuda, M., Yamaguchi, K., Machida, N., Esaki, T., Goto, M., Komatsu, Y., Nakajima, T. E., Sugimoto, N., Yoshida, K., Oki, E., Nishina, T., Tsuji, A. & 11 others, Fujii, H., Kunieda, K., Saitoh, S., Omuro, Y., Azuma, M., Iwamoto, Y., Taku, K., Fushida, S., Chen, L. T., Kang, Y. K. & Boku, N., 2019 Mar 15, In : Gastric Cancer. 22, 2, p. 344-354 11 p.

Research output: Contribution to journalArticle

Open Access
Esophageal Neoplasms
Stomach
Placebos
Drug Therapy
Survival
Stomach
Neoplasms
Weight Loss
Body Weight
Gastric Stump

Clinical utility of novel ultrathin single-balloon enteroscopy: A feasibility study

Takabayashi, K., Hosoe, N., Miyanaga, R., Fukuhara, S., Hukuhara, K., Mizuno, S., Naganuma, M., Yahagi, N., Ogata, H. & Kanai, T., 2019 Jan 1, In : Endoscopy. 51, 5, p. 468-471 4 p.

Research output: Contribution to journalArticle

Feasibility Studies
Conscious Sedation
Ileum
Outpatients
Safety

Comparison of olanexidine versus povidone-iodine for preventing surgical site infection in gastrointestinal surgery: Study protocol for a multicentre, single-blind, randomised controlled clinical trial

Takeuchi, M., Obara, H., Kawakubo, H., Shinoda, M., Okabayashi, K., Mayanagi, S., Irino, T., Fukuda, K., Nakamura, R., Wada, N., Kitago, M., Yagi, H., Abe, Y., Oshima, G., Hori, S., Tsuruta, M., Ishida, T., Yokose, T., Hirukawa, K., Isobe, Y. & 7 others, Sekimoto, Y., Harada, H., Maeda, Y., Shito, M., Kondo, T., Sato, Y. & Kitagawa, Y., 2019 May 1, In : BMJ open. 9, 5, e028269.

Research output: Contribution to journalArticle

Open Access
Povidone-Iodine
Surgical Wound Infection
Local Anti-Infective Agents
Randomized Controlled Trials
Research Ethics Committees
Feasibility Studies
Endoscopy
Names
Single-Balloon Enteroscopy

Determination of the optimal surgical procedure by identifying risk factors for pneumonia after transthoracic esophagectomy

Hayashi, M., Takeuchi, H., Nakamura, R., Suda, K., Wada, N., Kawakubo, H. & Kitagawa, Y., 2019 Jan 1, (Accepted/In press) In : Esophagus.

Research output: Contribution to journalArticle

Esophagectomy
Pneumonia
Thoracotomy
Logistic Models
Regression Analysis
1 Citation (Scopus)
Esophageal Neoplasms
Lymph Nodes
Neoplasm Metastasis
Neoplasm Micrometastasis
Dissection

Effect of First-line S-1 Plus Oxaliplatin With or Without Ramucirumab Followed by Paclitaxel Plus Ramucirumab on Advanced Gastric Cancer in East Asia: The Phase 2 RAINSTORM Randomized Clinical Trial

Yoshikawa, T., Muro, K., Shitara, K., Oh, D. Y., Kang, Y. K., Chung, H. C., Kudo, T., Chin, K., Kadowaki, S., Hamamoto, Y., Hironaka, S., Yoshida, K., Yen, C. J., Omuro, Y., Bai, L. Y., Maeda, K., Ozeki, A., Yoshikawa, R. & Kitagawa, Y., 2019 Aug 2, In : JAMA network open. 2, 8, p. e198243

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Far East
Paclitaxel
Stomach Neoplasms
Randomized Controlled Trials
3 Citations (Scopus)

Efficacy and safety of 0.6% sodium alginate solution in endoscopic submucosal dissection for esophageal and gastric neoplastic lesion: A randomized controlled study

Uemura, N., Oda, I., Saito, Y., Ono, H., Fujisaki, J., Matsuhashi, N., Ohata, K., Yahagi, N., Yada, T., Satoh, M., Tajiri, H., Inomata, M. & Kitano, S., 2019 Jan 1, In : Digestive Endoscopy.

Research output: Contribution to journalArticle

Open Access
Hyaluronic Acid
Stomach
Safety
Injections
Gastric Mucosa
6 Citations (Scopus)

Efficacy of afatinib or osimertinib plus cetuximab combination therapy for non-small-cell lung cancer with EGFR exon 20 insertion mutations

Hasegawa, H., Yasuda, H., Hamamoto, J., Masuzawa, K., Tani, T., Nukaga, S., Hirano, T., Kobayashi, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Lung Cancer. 127, p. 146-152 7 p.

Research output: Contribution to journalArticle

Insertional Mutagenesis
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Exons
Therapeutics

Experimental and clinicopathological analysis of HOXB9 in gastric cancer

Kato, F., Wada, N., Hayashida, T., Fukuda, K., Nakamura, R., Takahashi, T., Kawakubo, H., Takeuchi, H. & Kitagawa, Y., 2019 Mar 1, In : Oncology Letters. 17, 3, p. 3097-3102 6 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Lymphangiogenesis
Neoplasms
Vascular Endothelial Growth Factor D
Vascular Endothelial Growth Factor Receptor-3

Exploratory subgroup analysis of patients with prior trastuzumab use in the ATTRACTION-2 trial: a randomized phase III clinical trial investigating the efficacy and safety of nivolumab in patients with advanced gastric/gastroesophageal junction cancer

Satoh, T., Kang, Y. K., Chao, Y., Ryu, M. H., Kato, K., Cheol Chung, H., Chen, J. S., Muro, K., Ki Kang, W., Yeh, K. H., Yoshikawa, T., Oh, S. C., Bai, L. Y., Tamura, T., Lee, K. W., Hamamoto, Y., Kim, J. G., Chin, K., Oh, D. Y., Minashi, K. & 5 others, Cho, J. Y., Tsuda, M., Tanimoto, M., Chen, L. T. & Boku, N., 2019 Jan 1, In : Gastric Cancer.

Research output: Contribution to journalArticle

Open Access
Esophagogastric Junction
Phase III Clinical Trials
Stomach
Randomized Controlled Trials
Safety

Feasibility study comparing underwater endoscopic mucosal resection and conventional endoscopic mucosal resection for superficial non-ampullary duodenal epithelial tumor < 20 mm

Kiguchi, Y., Kato, M., Nakayama, A., Sasaki, M., Mizutani, M., Tsutsumi, K., Akimoto, T., Takatori, Y., Mutaguchi, M., Takabayashi, K., Ochiai, Y., Maehata, T., Kanai, T. & Yahagi, N., 2019 Jan 1, (Accepted/In press) In : Digestive Endoscopy.

Research output: Contribution to journalArticle

Open Access
Feasibility Studies
Neoplasms
Multivariate Analysis
Endoscopic Mucosal Resection
Observational Studies

Flexible traction method for endoscopic resection by using an endoscopic hand suturing technique

Goto, O., Sasaki, M., Akimoto, T., Kaise, M., Iwakiri, K. & Yahagi, N., 2019 Jan 1, In : Endoscopy. 51, 1, p. E3-E4

Research output: Contribution to journalComment/debate

Traction
Hand
1 Citation (Scopus)

Gastric lymphatic flows may change before and after endoscopic submucosal dissection: in vivo porcine survival models

Nohara, K., Goto, O., Takeuchi, H., Sasaki, M., Maehata, T., Yahagi, N. & Kitagawa, Y., 2019 Jan 1, (Accepted/In press) In : Gastric Cancer.

Research output: Contribution to journalArticle

Stomach
Swine
Indocyanine Green
Arteries
Gastrectomy

Haemostasis treatment using dual red imaging during endoscopic submucosal dissection: A multicentre, open-label, randomised controlled trial

Fujimoto, A., Saito, Y., Abe, S., Hoteya, S., Nomura, K., Yasuda, H., Matsuo, Y., Uraoka, T., Kuribayashi, S., Saito, I., Tsuji, Y., Maehata, T., Ochiai, Y., Nishizawa, T. & Yahagi, N., 2019 Mar 1, In : BMJ Open Gastroenterology. 6, 1, e000275.

Research output: Contribution to journalArticle

Open Access
Hemostasis
Randomized Controlled Trials
Light
Therapeutics
Dissection

How I do it: Endoscopic diagnosis for superficial non-ampullary duodenal epithelial tumors

Nakayama, A., Kato, M., Takatori, Y., Shimoda, M., Mizutani, M., Tsutsumi, K., Kiguchi, Y., Akimoto, T., Sasaki, M., Mutaguchi, M., Takabayashi, K., Maehata, T., Ochiai, Y., Kanai, T. & Yahagi, N., 2019 Jan 1, (Accepted/In press) In : Digestive Endoscopy.

Research output: Contribution to journalArticle

Neoplasms
Odds Ratio
Endoscopy
Observational Studies
Multivariate Analysis
1 Citation (Scopus)
Neoadjuvant Therapy
Cohort Studies
Retrospective Studies
Esophagectomy
Pleural Empyema

Management of perforation related to endoscopic submucosal dissection for superficial duodenal epithelial tumors

Fukuhara, S., Kato, M., Iwasaki, E., Sasaki, M., Tsutsumi, K., Kiguchi, Y., Akimoto, T., Takatori, Y., Nakayama, A., Maehata, T., Minami, K., Ogata, H., Kanai, T. & Yahagi, N., 2019 Jan 1, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Neoplasms
Pancreatic Ducts
Drainage
C-Reactive Protein
Endoscopic Mucosal Resection

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations

Ikemura, S., Yasuda, H., Matsumoto, S., Kamada, M., Hamamoto, J., Masuzawa, K., Kobayashi, K., Manabe, T., Arai, D., Nakachi, I., Kawada, I., Ishioka, K., Nakamura, M., Namkoong, H., Naoki, K., Ono, F., Araki, M., Kanada, R., Ma, B., Hayashi, Y. & 8 others, Mimaki, S., Yoh, K., Kobayashi, S. S., Kohno, T., Okuno, Y., Goto, K., Tsuchihara, K. & Soejima, K., 2019 May 14, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10025-10030 6 p.

Research output: Contribution to journalArticle

Open Access
Molecular Dynamics Simulation
Lung Neoplasms
Mutation
Pharmaceutical Preparations
Protein-Tyrosine Kinases

Monomer preference of EGFR tyrosine kinase inhibitors influences the synergistic efficacy of combination therapy with cetuximab

Oashi, A., Yasuda, H., Kobayashi, K., Tani, T., Hamamoto, J., Masuzawa, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Molecular cancer therapeutics. 18, 9, p. 1593-1601 9 p.

Research output: Contribution to journalArticle

Dimerization
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Therapeutics
4 Citations (Scopus)

Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial

Kato, K., Cho, B. C., Takahashi, M., Okada, M., Lin, C. Y., Chin, K., Kadowaki, S., Ahn, M. J., Hamamoto, Y., Doki, Y., Yen, C. C., Kubota, Y., Kim, S. B., Hsu, C. H., Holtved, E., Xynos, I., Kodani, M. & Kitagawa, Y., 2019 Nov, In : The Lancet Oncology. 20, 11, p. 1506-1517 12 p.

Research output: Contribution to journalArticle

Drug Therapy
Survival
Interstitial Lung Diseases
Research Personnel
docetaxel

Optimal use of anthracycline-free perioperative chemotherapy in HER2-positive breast cancer patients

Watanuki, R., Hayashida, T., Kawai, Y., Kikuchi, M., Nakashoji, A., Yokoe, T., Toyota, T., Seki, T., Takahashi, M. & Kitagawa, Y., 2019 Jan 1, In : International Journal of Clinical Oncology.

Research output: Contribution to journalArticle

Anthracyclines
Breast Neoplasms
Drug Therapy
Adjuvant Chemotherapy
Disease-Free Survival

Rebamipide solution as a submucosal injection material for possible prevention of gastric stenosis after endoscopic submucosal dissection

Fujimoto, A., Uraoka, T. & Yahagi, N., 2019 Apr 1, In : Digestive Endoscopy. 31, S1, p. 22-23 2 p.

Research output: Contribution to journalLetter

Open Access
Stomach
Pathologic Constriction
Injections
rebamipide
Endoscopic Mucosal Resection

Response:

Fujimoto, A., Uraoka, T. & Yahagi, N., 2019 Mar 1, In : Gastrointestinal Endoscopy. 89, 3, p. 645-646 2 p.

Research output: Contribution to journalLetter

Open Access
Stomach
Lymph Nodes
Neoplasm Metastasis
Carcinoma
Stomach Neoplasms
Open Access
Intestinal Perforation
Gastrointestinal Stromal Tumors
Kidney
Cyclosporine
Small Intestine
docetaxel
Fluorouracil
Cisplatin
Chemoradiotherapy
Esophagectomy
1 Citation (Scopus)

The clinical potential of oligonucleotide therapeutics against pancreatic cancer

Takakura, K., Kawamura, A., Torisu, Y., Koido, S., Yahagi, N. & Saruta, M., 2019 Jul 1, In : International journal of molecular sciences. 20, 13, 3331.

Research output: Contribution to journalReview article

Open Access
oligonucleotides
Oligonucleotides
Pancreatic Neoplasms
cancer
RNA

Thyroid and Parathyroid Functions After Pharyngo-Laryngo-Esophagectomy for Cervical Esophageal Cancer

Saito, Y., Kawakubo, H., Takami, H., Aoyama, J., Mayanagi, S., Irino, T., Fukuda, K., Suda, K., Nakamura, R., Wada, N. & Kitagawa, Y., 2019 Jan 1, In : Annals of Surgical Oncology.

Research output: Contribution to journalArticle

Esophagectomy
Esophageal Neoplasms
Uterine Cervical Neoplasms
Thyroid Gland
Hypoparathyroidism

Tongue surface model can predict radiation tongue mucositis due to intensity-modulated radiation therapy for head and neck cancer

Musha, A., Fukata, K., Saitoh, J. I., Shirai, K., Abe, T., Mizukami, T., Kawashima, M., Yokoo, S., Chikamatsu, K., Ohno, T. & Nakano, T., 2019 Jan 1, In : International Journal of Oral and Maxillofacial Surgery.

Research output: Contribution to journalArticle

Mucositis
Head and Neck Neoplasms
Tongue
Radiotherapy
Radiation

Treatment Results of Endoscopic Mucosal Resection with a Ligation Device for Duodenal Neuroendocrine Tumors

Fujimoto, A., Sasaki, M., Goto, O., Maehata, T., Ochiai, Y., Kato, M., Nakayama, A., Akimoto, T., Kuramoto, J., Hayashi, Y., Kameyama, K. & Yahagi, N., 2019 Mar 15, In : Internal medicine (Tokyo, Japan). 58, 6, p. 773-777 5 p.

Research output: Contribution to journalArticle

Open Access
Neuroendocrine Tumors
Ligation
Equipment and Supplies
Neoplasm Metastasis
Therapeutics
1 Citation (Scopus)
Hand-Foot Syndrome
Foot
Hand
Drug Therapy
Skin

Utility of the one-step nucleic acid amplification assay in sentinel node mapping for early gastric cancer patients

Shimada, A., Takeuchi, H., Nishi, T., Mayanagi, S., Fukuda, K., Suda, K., Nakamura, R., Wada, N., Kawakubo, H., Nakahara, T., Kameyama, K. & Kitagawa, Y., 2019 Jan 1, (Accepted/In press) In : Gastric Cancer.

Research output: Contribution to journalArticle

Nucleic Acids
Stomach Neoplasms
Lymph Nodes
Gastrectomy
Neoplasm Metastasis

大腸癌化学療法の変遷と展望

Translated title of the contribution: Systemic chemotherapy for metastatic colorectal cancer: History and New eraShimozaki, K., Inokuchi, K. & Hamamoto, Y., 2019 Jan 1, In : Journal of Japanese Society of Gastroenterology. 116, 11, p. 902-912 11 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
History
Drug Therapy
2018
1 Citation (Scopus)

Absence of high-risk stigmata predicts good prognosis even in severely anemic patients with suspected acute upper gastrointestinal bleeding

Horibe, M., Ogura, Y., Matsuzaki, J., Kaneko, T., Yokota, T., Okawa, O., Nakatani, Y., Iwasaki, E., Nishizawa, T., Hosoe, N., Masaoka, T., Yahagi, N., Namiki, S. & Kanai, T., 2018 Jan 1, (Accepted/In press) In : United European Gastroenterology Journal.

Research output: Contribution to journalArticle

Christianity
Hemorrhage
Blood Transfusion
Hemoglobins
Mortality
2 Citations (Scopus)

Advanced Endoscopic Treatment of Gastric and Duodenal Neoplasms: Beyond Standard EMR and ESD

Kato, M. & Yahagi, N., 2018 Oct 1, In : American Journal of Gastroenterology. 113, 10, p. 1423-1426 4 p.

Research output: Contribution to journalArticle

Duodenal Neoplasms
Stomach Neoplasms

A gastric follicular lymphoma presenting as a submucosal tumor with a diagnosis determined by endoscopic resection

Fujimoto, A., Akimoto, T., Nakayama, A., Mikami, S., Tsujikawa, H., Kameyama, K., Okamoto, S., Maehata, T., Ochiai, Y., Goto, O., Kato, M., Sasaki, M., Uraoka, T. & Yahagi, N., 2018 Jan 1, In : Internal Medicine. 57, 13, p. 1849-1853 5 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Neoplasms
Endosonography
Colonoscopy
Stomach
2 Citations (Scopus)

Air Bubble Sign: A New Screening Method for Anastomotic Leakage After Esophagectomy for Esophageal Cancer

Shoji, Y., Takeuchi, H., Fukuda, K., Nakamura, R., Wada, N., Kawakubo, H. & Kitagawa, Y., 2018 Jan 9, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Anastomotic Leak
Esophagectomy
Esophageal Neoplasms
Air
Tomography
2 Citations (Scopus)

Analysis of sensitivity and cell death pathways mediated by anti-cancer drugs using three-dimensional culture system

Kinoshita, T., Higuchi, H., Ayano-Kabashima-Niibe, Sakai, G., Hamamoto, Y., Takaishi, H. & Kanai, T., 2018 Jan 1, In : International Journal of Cancer Research. 14, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

irinotecan
Cell Death
Apoptosis
Caspases
Pharmaceutical Preparations
1 Citation (Scopus)
Esophagectomy
Pneumonia
Randomized Controlled Trials
Paralysis
Anastomotic Leak

Antitumor effect of lapatinib and cytotoxic agents by suppression of E2F1 in HER2-positive breast cancer

Matsumoto, A., Hayashida, T., Takahashi, M., Jinno, H. & Kitagawa, Y., 2018 Jul 1, In : Molecular Medicine Reports. 18, 1, p. 958-964 7 p.

Research output: Contribution to journalArticle

E2F1 Transcription Factor
Cytotoxins
Breast Neoplasms
Thymidylate Synthase
gemcitabine
3 Citations (Scopus)
Stomach Neoplasms
Neoplasms
Therapeutics
Immunotherapy
Japan
7 Citations (Scopus)

Clinical impact of closure of the mucosal defect after duodenal endoscopic submucosal dissection

Kato, M., Ochiai, Y., Fukuhara, S., Maehata, T., Sasaki, M., Kiguchi, Y., Akimoto, T., Fujimoto, A., Nakayama, A., Kanai, T. & Yahagi, N., 2018 Jan 1, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Length of Stay
C-Reactive Protein
Logistic Models
Odds Ratio
Confidence Intervals

Clinicopathologic features of hormone-receptor-positive breast cancer patients with late recurrence

Murata, T., Jinno, H., Takahashi, M., Shimoda, M., Hayashida, T., Kameyama, K. & Kitagawa, Y., 2018 Jan 1, (Accepted/In press) In : Breast Journal.

Research output: Contribution to journalArticle

Hormones
Breast Neoplasms
Recurrence
Tamoxifen
Disease-Free Survival
1 Citation (Scopus)

Current status and challenges of endoscopic treatments for duodenal tumors

Ochiai, Y., Kato, M., Kiguchi, Y., Akimoto, T., Nakayama, A., Sasaki, M., Fujimoto, A., Maehata, T., Goto, O. & Yahagi, N., 2018 Dec 1, In : Digestion. 99, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Duodenum
Adenoma
Carcinoma
1 Citation (Scopus)

Current status and feasibility of endoscopic full-thickness resection in Japan: Results of a questionnaire survey

Yamamoto, Y., Uedo, N., Abe, N., Mori, H., Ikeda, H., Kanzaki, H., Hirasawa, K., Yoshida, N., Goto, O., Morita, S. & Zhou, P., 2018 Apr 1, In : Digestive Endoscopy. 30, p. 2-6 5 p.

Research output: Contribution to journalEditorial

Japan
Surveys and Questionnaires