Department of Transfusion Medicine and Cell Therapy

Research Output 1981 2019

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2008
16 Citations (Scopus)

Haemostatic effects of polymerized albumin particles carrying fibrinogen γ-chain dodecapeptide as platelet substitutes in severely thrombocytopenic rabbits

Okamura, Y., Fujie, T., Nogawa, M., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2008 Jun, In : Transfusion Medicine. 18, 3, p. 158-166 9 p.

Research output: Contribution to journalArticle

Hemostatics
Fibrinogen
Albumins
Blood Platelets
Rabbits
14 Citations (Scopus)
Whole-Body Irradiation
Hematopoietic Stem Cell Transplantation
Cytarabine
Granulocyte Colony-Stimulating Factor
Acute Myeloid Leukemia
2007
12 Citations (Scopus)

A role for glycosphingolipid-enriched microdomains in platelet glycoprotein Ib-mediated platelet activation

Jin, W., Inoue, O., Tamura, N., Suzuki-inoue, K., Satoh, K., Berndt, M. C., Handa, M., Goto, S. & Ozaki, Y., 2007 May, In : Journal of Thrombosis and Haemostasis. 5, 5, p. 1034-1040 7 p.

Research output: Contribution to journalArticle

Platelet Glycoprotein GPIb-IX Complex
Platelet Membrane Glycoproteins
Glycosphingolipids
Platelet Activation
Blood Platelets
15 Citations (Scopus)

Blood eosinophilia as a marker of favorable outcome after allogeneic stem cell transplantation

Aisa, Y., Mori, T., Nakazato, T., Shimizu, T., Yamazaki, R., Ikeda, Y. & Okamoto, S., 2007 Sep, In : Transplant International. 20, 9, p. 761-770 10 p.

Research output: Contribution to journalArticle

Eosinophilia
Stem Cell Transplantation
Graft vs Host Disease
Survival
Incidence
6 Citations (Scopus)

Hepatic veno-occlusive disease after tranexamic acid administration in oatients undergoing allogeneic hematopoietic stem cell transplantation

Mori, T., Aisa, Y., Shimizu, T., Yamazaki, R., Mihara, A., Yajima, T., Hibi, T., Ikeda, Y. & Okamoto, S., 2007 Sep, In : American Journal of Hematology. 82, 9, p. 838-839 2 p.

Research output: Contribution to journalArticle

Hepatic Veno-Occlusive Disease
Tranexamic Acid
Hematopoietic Stem Cell Transplantation
Antifibrinolytic Agents
Plasminogen
13 Citations (Scopus)

Myelitis associated with human herpes virus 6 (HHV-6) after allogeneic cord blood transplantation

Mori, T., Mihara, A., Yamazaki, R., Shimizu, T., Aisa, Y., Suzuki, S., Ikeda, Y. & Okamoto, S., 2007, In : Scandinavian Journal of Infectious Diseases. 39, 3, p. 276-278 3 p.

Research output: Contribution to journalArticle

Myelitis
Fetal Blood
Transplantation
Viruses
Hematopoietic Stem Cell Transplantation
74 Citations (Scopus)
Human Herpesvirus 6
Hematopoietic Stem Cell Transplantation
Central Nervous System Diseases
Transplantation
Fetal Blood
9 Citations (Scopus)
Unrelated Donors
Tacrolimus
Graft vs Host Disease
Hematologic Neoplasms
Fetal Blood
11 Citations (Scopus)
Whole-Body Irradiation
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Cytarabine
Granulocyte Colony-Stimulating Factor
2006
3 Citations (Scopus)

Acinetobacter lwoffii septicemia associated with a peripheral intravascular catheter

Mori, T., Nakazato, T., Yamazaki, R., Ikeda, Y. & Okamoto, S., 2006 Jul 18, In : Internal Medicine. 45, 12, p. 803-804 2 p.

Research output: Contribution to journalArticle

Acinetobacter Infections
Acinetobacter
Indwelling Catheters
Bone Marrow Transplantation
Sepsis
6 Citations (Scopus)

Analyzing the mechanism of Rap1 activation in platelets: Rap1 activation is related to the release reaction mediated through the collagen receptor GPVI

Jung, S. M., Ohnuma, M., Watanabe, N., Sonoda, M., Handa, M. & Moroi, M., 2006, In : Thrombosis Research. 118, 4, p. 509-521 13 p.

Research output: Contribution to journalArticle

Platelet Activation
Integrins
Phosphatidylinositol 3-Kinases
Adenosine Diphosphate
Tyrosine
20 Citations (Scopus)

Brief oral cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients

Mori, T., Yamazaki, R., Aisa, Y., Nakazato, T., Kudo, M., Yashima, T., Kondo, S., Ikeda, Y. & Okamoto, S., 2006 Apr, In : Supportive Care in Cancer. 14, 4, p. 392-395 4 p.

Research output: Contribution to journalArticle

Stomatitis
Cryotherapy
Melphalan
Hematopoietic Stem Cells
Transplants
15 Citations (Scopus)

Cryotherapy for the prevention of high-dose melphalan-induced oral mucositis [2]

Mori, T., Aisa, Y., Yamazaki, R., Mihara, A., Ikeda, Y. & Okamoto, S., 2006 Nov, In : Bone Marrow Transplantation. 38, 9, p. 637-638 2 p.

Research output: Contribution to journalArticle

Alkylating Antineoplastic Agents
Peripheral Blood Stem Cell Transplantation
Stomatitis
Cryotherapy
Melphalan
3 Citations (Scopus)

Excretion of cytosine arabinoside in saliva after its administration at high doses

Mori, T., Yamazaki, R., Nakazato, T., Aisa, Y., Enoki, S., Arai, M., Ikeda, Y. & Okamoto, S., 2006 Jun, In : Anti-Cancer Drugs. 17, 5, p. 597-598 2 p.

Research output: Contribution to journalArticle

Cytarabine
Saliva
Hematologic Neoplasms
Cerebrospinal Fluid
High Pressure Liquid Chromatography
3 Citations (Scopus)

Gelatinous degeneration in a recipient of allogeneic bone marrow transplantation [3]

Aisa, Y., Mori, T., Nakazato, T., Yamazaki, R., Ikeda, Y. & Okamoto, S., 2006 Dec, In : International Journal of Hematology. 84, 5, p. 465-467 3 p.

Research output: Contribution to journalArticle

Transplantation Chimera
Primary Myelofibrosis
Homologous Transplantation
Graft vs Host Disease
Bone Marrow Transplantation
27 Citations (Scopus)
Platelet Glycoprotein GPIb-IX Complex
Glycoproteins
Latex
Platelets
Latexes
32 Citations (Scopus)

N-terminal region of CCAAT/enhancer-binding protein ε is critical for cell cycle arrest, apoptosis, and functional maturation during myeloid differentiation

Nakajima, H., Watanabe, N., Shibata, F., Kitamura, T., Ikeda, Y. & Handa, M., 2006 May 19, In : Journal of Biological Chemistry. 281, 20, p. 14494-14502 9 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Cell Cycle Checkpoints
Cells
Apoptosis
Apoptosis Regulatory Proteins
11 Citations (Scopus)
Stem Cell Transplantation
Hematologic Neoplasms
HLA Antigens
Cytotoxic T-Lymphocytes
Tissue Donors
5 Citations (Scopus)
valacyclovir
Unrelated Donors
Homologous Transplantation
Cytomegalovirus Infections
Bone Marrow Transplantation
38 Citations (Scopus)
Hematopoietic Stem Cell Transplantation
Thrombocytopenia
Stem Cell Transplantation
Blood Platelets
Thrombopoietin
8 Citations (Scopus)

Successful management of liver injury caused by imatinib mesylate in a patient with previously untreated chronic myelogenous leukemia in the chronic phase [13]

Yamazaki, R., Okamoto, S., Chen, C. K., Tada, S., Saito, H., Shibata, R., Sakamoto, M., Mori, T. & Ikeda, Y., 2006 Jul, In : Leukemia and Lymphoma. 47, 7, p. 1427-1430 4 p.

Research output: Contribution to journalArticle

Piperazines
Leukemia, Myeloid, Chronic Phase
Blast Crisis
Pyrimidines
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
6 Citations (Scopus)

Systemic infection due to Acremonium after allogeneic peripheral blood stem cell transplantation

Yamazaki, R., Mori, T., Aisa, Y., Nakazato, T., Mihara, A., Ikeda, Y. & Okamoto, S., 2006 Sep 5, In : Internal Medicine. 45, 16, p. 989-990 2 p.

Research output: Contribution to journalArticle

Acremonium
Peripheral Blood Stem Cell Transplantation
Mycoses
Myelodysplastic Syndromes
Homologous Transplantation
2 Citations (Scopus)

Varicella-zoster virus infection under administration of ganciclovir after allogeneic bone marrow transplantation

Mori, T., Shimizu, T., Yamazaki, R., Aisa, Y., Nakazato, T., Ikeda, Y. & Okamoto, S., 2006 Mar, In : Scandinavian Journal of Infectious Diseases. 38, 3, p. 227-228 2 p.

Research output: Contribution to journalArticle

Virus Activation
Ganciclovir
Human Herpesvirus 3
Homologous Transplantation
Herpes Zoster
2005
11 Citations (Scopus)

Altered metabolism of tacrolimus in hepatic veno-occlusive disease

Mori, T., Shimizu, T., Yamazaki, R., Nakazato, T., Ikeda, Y. & Okamoto, S., 2005 Oct, In : Transplant International. 18, 10, p. 1215-1217 3 p.

Research output: Contribution to journalArticle

Hepatic Veno-Occlusive Disease
Tacrolimus
Hematopoietic Stem Cell Transplantation
Graft Rejection
Hepatomegaly
7 Citations (Scopus)
Benign Mucous Membrane Pemphigoid
Follicular Lymphoma
Oropharynx
Stem Cell Transplantation
Graft vs Host Disease
21 Citations (Scopus)

Effects of immunosuppressive agents on magnesium metabolism early after allogeneic hematopoietic stem cell transplantation

Aisa, Y., Mori, T., Nakazato, T., Shimizu, T., Yamazaki, R., Ikeda, Y. & Okamoto, S., 2005 Oct 27, In : Transplantation. 80, 8, p. 1046-1050 5 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Immunosuppressive Agents
Magnesium
Tacrolimus
Cyclosporine
36 Citations (Scopus)
Immunodominant Epitopes
T-Lymphocyte Epitopes
Hematopoietic Stem Cell Transplantation
HLA Antigens
Cytomegalovirus
46 Citations (Scopus)

Hemostatic effects of phospholipid vesicles carrying fibrinogen γ chain dodecapeptide in vitro and in vivo

Okamura, Y., Maekawa, I., Teramura, Y., Maruyama, H., Handa, M., Ikeda, Y. & Takeoka, S., 2005 Nov, In : Bioconjugate Chemistry. 16, 6, p. 1589-1596 8 p.

Research output: Contribution to journalArticle

Phospholipids
Hemostatics
Fibrinogen
Polyethylene glycols
Blood Platelets
38 Citations (Scopus)

Membrane-proximal α/β stalk interactions differentially regulate integrin activation

Kamata, T., Handa, M., Sato, Y., Ikeda, Y. & Aiso, S., 2005 Jul 1, In : Journal of Biological Chemistry. 280, 26, p. 24775-24783 9 p.

Research output: Contribution to journalArticle

Integrins
Chemical activation
Ligands
Membranes
Divalent Cations
13 Citations (Scopus)

Platelet glycoprotein Ib alpha polymorphisms affect the interaction with von Willebrand factor under flow conditions

Matsubara, Y., Murata, M., Hayashi, T., Suzuki, K., Okamura, Y., Handa, M., Ishihara, H., Shibano, T. & Ikeda, Y., 2005 Feb, In : British Journal of Haematology. 128, 4, p. 533-539 7 p.

Research output: Contribution to journalArticle

Platelet Glycoprotein GPIb-IX Complex
Platelet Membrane Glycoproteins
von Willebrand Factor
Thrombosis
Alleles
16 Citations (Scopus)

Tacrolimus-azithromycin interaction in a recipient of allogeneic bone marrow transplantation [2]

Mori, T., Aisa, Y., Nakazato, T., Yamazaki, R., Ikeda, Y. & Okamoto, S., 2005 Jun, In : Transplant International. 18, 6, p. 757-758 2 p.

Research output: Contribution to journalArticle

Azithromycin
Homologous Transplantation
Tacrolimus
Bone Marrow Transplantation
Drug Interactions
20 Citations (Scopus)

The effects of platelet-rich plasma on cutaneous incisional wound healing in rats [1]

Kimura, A., Ogata, H., Yazawa, M., Watanabe, N., Mori, T. & Nakajima, T., 2005 Dec, In : Journal of Dermatological Science. 40, 3, p. 205-208 4 p.

Research output: Contribution to journalArticle

Growth Substances
Platelets
Rats
Blood Proteins
Skin
1 Citation (Scopus)

Thrombopoietin (TPO)

Ishida, A. & Handa, M., 2005, In : Nippon rinsho. Japanese journal of clinical medicine. 63 Suppl 8, p. 618-620 3 p.

Research output: Contribution to journalArticle

Diagnostic Reagent Kits
Thrombopoietin
Idiopathic Thrombocytopenic Purpura
Aplastic Anemia
Myelodysplastic Syndromes
2004
27 Citations (Scopus)

Basic studies on the bone formation ability by platelet rich plasma in rabbits

Yazawa, M., Ogata, H., Kimura, A., Nakajima, T., Mori, T. & Watanabe, N., 2004, In : Journal of Craniofacial Surgery. 15, 3, p. 1 1 p.

Research output: Contribution to journalArticle

Fibrin Tissue Adhesive
Platelet-Rich Plasma
Osteogenesis
Rabbits
Bone and Bones
5 Citations (Scopus)

Diagnostic usefulness of bronchoalveolar lavage in Hermansky-Pudlak syndrome: A case with double lung cancers

Takahashi, K., Ishida, T., Ogura, G., Ishii, T., Oshima, K., Sato, S., Muroi, M., Kanazawa, K., Saito., J., Otsuka, Y., Watanabe, K., Handa, M. & Munakata, M., 2004 Oct, In : Internal Medicine. 43, 10, p. 972-976 5 p.

Research output: Contribution to journalArticle

Hermanski-Pudlak Syndrome
Ceroid
Bronchoalveolar Lavage Fluid
Bronchoalveolar Lavage
Cell Biology
4 Citations (Scopus)

Influence of antiplatelet substances on platelet-rich plasma

Yazawa, M., Ogata, H., Nakajima, T. & Watanabe, N., 2004 Jun, In : Journal of Oral and Maxillofacial Surgery. 62, 6, p. 714-718 5 p.

Research output: Contribution to journalArticle

Platelet-Rich Plasma
Blood Platelets
Intercellular Signaling Peptides and Proteins
Platelet-Derived Growth Factor
Transforming Growth Factors
7 Citations (Scopus)

Quantitative analysis of PRAME for detection of minimal residual disease in leukemia.

Matsushita, M., Yamazaki, R. & Kawakami, Y., 2004, In : Methods in molecular medicine. 97, p. 267-275 9 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Neoplasm Antigens
Tumor Biomarkers
Reverse Transcriptase Polymerase Chain Reaction
Leukemia
2003
54 Citations (Scopus)

Basic studies on the clinical applications of platelet-rich plasma

Yazawa, M., Ogata, H., Nakajima, T., Mori, T., Watanabe, N. & Handa, M., 2003, In : Cell Transplantation. 12, 5, p. 509-518 10 p.

Research output: Contribution to journalArticle

Platelet-Rich Plasma
Platelets
Blood Platelets
Plasmas
Fibrin Tissue Adhesive
15 Citations (Scopus)

Bernard-Soulier syndrome with a homozygous 13 base pair deletion in the signal peptide-coding region of the platelet glycoprotein Ibβ gene

Watanabe, R., Ishibashi, T., Saitoh, Y., Shichishima, T., Maruyama, Y., Enomoto, Y., Handa, M., Oda, A., Ambo, H., Murata, M. & Ikeda, Y., 2003 Jun, In : Blood Coagulation and Fibrinolysis. 14, 4, p. 387-394 8 p.

Research output: Contribution to journalArticle

Bernard-Soulier Syndrome
Platelet Glycoprotein GPIb-IX Complex
Platelet Membrane Glycoproteins
Protein Sorting Signals
Base Pairing
83 Citations (Scopus)

Different effects of various anti-GPIIB-IIIa agents on shear-induced platelet activation and expression of procoagulant activity

Goto, S., Tamura, N., Li, M., Handa, M., Ikeda, Y., Handa, S. & Ruggri, Z. M., 2003 Sep, In : Journal of Thrombosis and Haemostasis. 1, 9, p. 2022-2030 9 p.

Research output: Contribution to journalArticle

tirofiban
Platelet Activation
P-Selectin
Platelet-Rich Plasma
Blood Platelets
4 Citations (Scopus)
Neoplasm Drug Resistance
Piperazines
bcr-abl Fusion Proteins
Blast Crisis
Pyrimidines
9 Citations (Scopus)

Granulocyte transfusion as a treatment for enterococcal meningoencephalitis after allogeneic bone marrow transplantation from an unrelated donor

Tsukada, Y., Nagayama, H., Mori, T., Shimizu, T., Sato, N., Takayama, N., Ishida, A., Handa, M., Ikeda, Y. & Okamoto, S., 2003 Jan, In : Bone Marrow Transplantation. 31, 1, p. 69-72 4 p.

Research output: Contribution to journalArticle

Unrelated Donors
Meningoencephalitis
Homologous Transplantation
Bone Marrow Transplantation
Granulocytes
19 Citations (Scopus)

Hemostatic effects of polymerized albumin particles bearing rGPIa/IIa in thrombocytopenic mice

Teramura, Y., Okamura, Y., Takeoka, S., Tsuchiyama, H., Narumi, H., Kainoh, M., Handa, M., Ikeda, Y. & Tsuchida, E., 2003 Jun 20, In : Biochemical and Biophysical Research Communications. 306, 1, p. 256-260 5 p.

Research output: Contribution to journalArticle

Bearings (structural)
Hemostatics
Albumins
Platelets
Blood Platelets

Measurement of plasma von Willebrand factor cleaving protease in patients with varied thrombotic microangiopathy

Katagiri, H., Kawai, Y., Sugizaki, N., Sakai, K., Handa, M., Okamoto, S. & Watanabe, K., 2003, In : Rinsho byori. The Japanese journal of clinical pathology. 51, 6, p. 516-521 6 p.

Research output: Contribution to journalArticle

Thrombotic Microangiopathies
von Willebrand Factor
Thrombotic Thrombocytopenic Purpura
Plasma Exchange
Thrombocytopenia
28 Citations (Scopus)
Melanoma-Specific Antigens
Hematologic Neoplasms
Leukemia
Therapeutics
Residual Neoplasm
2002
6 Citations (Scopus)

A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibα

Matsubara, Y., Murata, M., Moriki, T., Yokoyama, K., Watanabe, N., Nakajima, H., Handa, M., Kawano, K., Aoki, N., Yoshino, H. & Ikeda, Y., 2002, In : Thrombosis and Haemostasis. 87, 5, p. 867-872 6 p.

Research output: Contribution to journalArticle

Platelet Glycoprotein GPIb-IX Complex
Platelet Membrane Glycoproteins
von Willebrand Factor
Leucine
Ristocetin
36 Citations (Scopus)

Carbon monoxide modulates endotoxin-induced microvascular leukocyte adhesion through platelet-dependent mechanisms

Morisaki, H., Katayama, T., Kotake, Y., Ito, M., Handa, M., Ikeda, Y., Takeda, J. & Suematsu, M., 2002 Sep, In : Anesthesiology. 97, 3, p. 701-709 9 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Endotoxins
Heme Oxygenase-1
Leukocytes
Blood Platelets
49 Citations (Scopus)

Dose-adjusted preemptive therapy for cytomegalovirus disease based on real-time polymerase chain reaction after allogeneic hematopoietic stem cell transplantation

Mori, T., Okamoto, S., Watanabe, R., Yajima, T., Iwao, Y., Yamazaki, R., Nakazato, T., Sato, N., Iguchi, T., Nagayama, H., Takayama, N., Hibi, T. & Ikeda, Y., 2002, In : Bone Marrow Transplantation. 29, 9, p. 777-782 6 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Ganciclovir
Cytomegalovirus
Real-Time Polymerase Chain Reaction
Viral Load

Localized recurrence of acute lymphoblastic leukemia-L3 in the tonsil after 3-years' remission

Yamazaki, R., Takayama, N., Hamano, Y., Mori, T., Okamoto, S. & Ikeda, Y., 2002, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 43, 11, p. 1004-1008 5 p.

Research output: Contribution to journalArticle

Palatine Tonsil
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Burkitt Lymphoma
Recurrence
Peripheral Blood Stem Cell Transplantation
12 Citations (Scopus)

Rapid and efficient generation of lentivirally gene-modified dendritic cells from DC progenitors with bone marrow stromal cells

Sumimoto, H., Tsuji, T., Miyoshi, H., Hagihara, M., Yamazaki, R., Okamoto, S., Ikeda, Y., Takahashi, T. & Kawakami, Y., 2002 Dec 20, In : Journal of Immunological Methods. 271, 1-2, p. 153-165 13 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Dendritic Cells
Genes
Fetal Blood
Stem Cell Factor