The Sakaguchi Laboratory

Research Output

1998

Evaluation of the role of N-linked oligosaccharides in rat placental lactogen action by site-directed mutagenesis

Hattori, N., Nukada, T., Oda, M., Tanaka, S., Ogawa, T. & Shiota, K., 1998 Oct, In : Endocrine journal. 45, 5, p. 659-674 16 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Expression and functional analysis of a hemopoietic progenitor antigen, NJ-1 (114/A10), in the megakaryocytic lineage

Duan, Y., Naruse, T., Nakamura, M., Yamaguchi, Y., Kawashima, T., Morikawa, Y., Kitamura, T. & Suda, T., 1998 Dec 18, In : Biochemical and Biophysical Research Communications. 253, 2, p. 401-406 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at the embryo implantation site in mouse

Yotsumoto, S., Shimada, T., Cui, C. Y., Nakashima, H., Fujiwara, H. & Ko, M. S. H., 1998 Nov 15, In : Developmental Biology. 203, 2, p. 264-275 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Fluid secretion in interlobular ducts isolated from guinea-pig pancreas

Ishiguro, H., Naruse, S., Steward, M. C., Kitagawa, M., Ko, S. B. H., Hayakawa, T. & Case, R. M., 1998 Sep 1, In : Journal of Physiology. 511, 2, p. 407-422 16 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Forced GATA-1 expression in the murine myeloid cell line M1: Induction of c-Mpl expression and megakaryocytic/erythroid differentiation

Yamaguehi, Y., Zon, L. I., Ackerman, S. J., Yamamoto, M. & Suda, T., 1998 Jan 15, In : Blood. 91, 2, p. 450-457 8 p.

Research output: Contribution to journalArticle

Open Access
71 Citations (Scopus)

Function of the receptor tyrosine kin ÄSE, HTK/EPHB4 and its ligand, HTKL/EPHRIN-B2 in erythropoiesis

Inada, T., Sakano, S. & Suda, T., 1998 Dec 1, In : Experimental Hematology. 26, 8, 1 p.

Research output: Contribution to journalArticle

Generation of a monoclonal antibody that induces apoptosis of hematopoietic cells

Mio, H., Satoh, M., Yokokawa, S., Nishio, H., Suda, T. & Tamaoki, T., 1998 Feb 24, In : Biochemical and Biophysical Research Communications. 243, 3, p. 727-731 5 p.

Research output: Contribution to journalArticle

Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome

Ko, M. S. H., Threat, T. A., Wang, X., Horton, J. H., Cui, Y., Wang, X., Pryor, E., Paris, J., Wells-Smith, J., Kitchen, J. R., Rowe, L. B., Eppig, J., Satoh, T., Brant, L., Fujiwara, H., Yotsumoto, S. & Nakashima, H., 1998 Nov, In : Human molecular genetics. 7, 12, p. 1967-1978 12 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Hematopoietic activity of tek-ligand, angiopoietins in murine bone marrow cells

Huang, X. L., Takakura, N. & Suda, T., 1998 Dec 1, In : Experimental Hematology. 26, 8, 1 p.

Research output: Contribution to journalArticle

Islet Cell Tumor in von Hippel-Lindau Disease

Mizlno, N., Naruse, S., Kitagawa, M., Ishiguro, H., Nakak, Y., Ihda, H., Iizuka, N., Ito, O., Seki, Y., Ko, S. B. H., Yoshikawa, T., Hayakawa, T., Sano, T., Kamiya, J., Nimura, Y. & Nagasaka, T., 1998, In : Internal Medicine. 37, 3, p. 295-299 5 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Macrophage-stimulating protein (MSP) and its receptor, RON, stimulate human osteoclast activity but not proliferation: Effect of MSP distinct from that of hepatocyte growth factor

Kurihara, N., Tatsumi, J., Arai, F., Iwama, A. & Suda, T., 1998 Oct 29, In : Experimental Hematology. 26, 11, p. 1080-1085 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene

Yamaguchi, Y., Ackerman, S. J., Minegishi, N., Takiguchi, M., Yamamoto, M. & Suda, T., 1998 May 1, In : Blood. 91, 9, p. 3447-3458 12 p.

Research output: Contribution to journalArticle

Open Access
57 Citations (Scopus)

Models of lineage switching in hematopoietic development: A new myeloid-committed eosinophil cell line (YJ) demonstrates trilineage potential

Yamaguchi, Y., Nishio, H., Kasahara, T., Ackerman, S. J., Koyanagi, H. & Suda, T., 1998 Jan 1, In : Leukemia. 12, 9, p. 1430-1439 10 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Molecular cloning and characterization of a new member of the rat placental prolactin (PRL) family, PRL-like protein H

Iwatsuki, K., Oda, M., Sun, W., Tanaka, S., Ogawa, T. & Shiota, K., 1998 Jan 1, In : Endocrinology. 139, 12, p. 4976-4983 8 p.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)

Overexpression of C-terminal Src kinase homologous kinase suppresses activation of Lyn tyrosine kinase required for VLA5-mediated Dami cell spreading

Hirao, A., Huang, X. L., Suda, T. & Yamaguchi, N., 1998 Apr 17, In : Journal of Biological Chemistry. 273, 16, p. 10004-10010 7 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

The effect of VIP/PACAP family of peptides on pancreatic blood flow and secretion in conscious dogs

Ito, O., Naruse, S., Kitagawa, M., Ishiguro, H., Ko, S., Nakajima, M. & Hayakawa, T., 1998 Nov 30, In : Regulatory Peptides. 78, 1-3, p. 105-112 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1999

A common signaling pathway via Syk and Lyn tyrosine kinases generated from capping of the sialomucins CD34 and CD43 in immature hematopoietic cells

Tada, J. I., Omine, M., Suda, T. & Yamaguchi, N., 1999 Jun 1, In : Blood. 93, 11, p. 3723-3735 13 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Arginine vasopressin inhibits fluid secretion in guinea pig pancreatic duct cells

Ko, S. B. H., Naruse, S., Kitagawa, M., Ishiguro, H., Murakami, M. & Hayakawa, T., 1999 Jul, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 277, 1 40-1, p. G48-G54

Research output: Contribution to journalArticle

16 Citations (Scopus)

C/EBPβ and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: Implication for C/EBPβ activity in eosinophil gene expression

Yamaguchi, Y., Nishio, H., Kishi, K., Ackerman, S. J. & Suda, T., 1999 Aug 15, In : Blood. 94, 4, p. 1429-1439 11 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo

De Maximy, A. A., Nakatake, Y., Moncada, S., Itoh, N., Thiery, J. P. & Bellusci, S., 1999 Mar 1, In : Mechanisms of Development. 81, 1-2, p. 213-216 4 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor κB (RANK) receptors

Arai, F., Miyamoto, T., Ohneda, O., Inada, T., Sudo, T., Brasel, K., Miyata, T., Anderson, D. M. & Suda, T., 1999 Dec 20, In : Journal of Experimental Medicine. 190, 12, p. 1741-1754 14 p.

Research output: Contribution to journalArticle

475 Citations (Scopus)

Endothelial growth factor receptors in human fetal heart

Partanen, T. A., Makinen, T., Arola, J., Suda, T., Weich, H. A. & Alitalo, K., 1999 Aug 10, In : Circulation. 100, 6, p. 583-586 4 p.

Research output: Contribution to journalArticle

Open Access
43 Citations (Scopus)

Green fluorescent protein as a selectable marker of retrovirally transduced hematopoietic progenitors

Kume, A., Hashiyama, M., Suda, T. & Ozawa, K., 1999 Jan 1, In : Stem Cells. 17, 4, p. 226-232 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Induction of cell shape changes through activation of the interleukin-3 common β chain receptor by the RON receptor-type tyrosine kinase

Mera, A., Suga, M., Ando, M., Suda, T. & Yamaguchi, N., 1999 May 28, In : Journal of Biological Chemistry. 274, 22, p. 15766-15774 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

In vitro effects of angiopoietins and VEGF on hematopoietic and endothelial cells

Huang, X. L., Takakura, N. & Suda, T., 1999 Oct 14, In : Biochemical and Biophysical Research Communications. 264, 1, p. 133-138 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

In vitro hematopoietic and endothelial cell development from cells expressing TEK receptor in murine aorta-gonad-mesonephros region

Hamaguchi, I., Huang, X. L., Takakura, N., Tada, J. I., Yamaguchi, Y., Kodama, H. & Suda, T., 1999 Mar 1, In : Blood. 93, 5, p. 1549-1556 8 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Novel association of the Src family kinases, Hck and c-Fgr, with CCR3 receptor stimulation: A possible mechanism for eotaxin-induced human eosinophil chemotaxis

El-Shazly, A., Yamaguchi, N., Masuyama, K., Suda, T. & Ishikawa, T., 1999 Oct 14, In : Biochemical and Biophysical Research Communications. 264, 1, p. 163-170 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Regulation of B-1 cell activation and its autoantibody production by Lyn kinase-regulated signallings

Ochi, H., Takeshita, H., Suda, T., Nisitani, S., Honjo, T. & Watanabe, T., 1999 Dec 1, In : Immunology. 98, 4, p. 595-603 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Two novel mouse genes - Nubp2, mapped to the t-complex on chromosome 17, and Nubp1, mapped to chromosome 16 - Establish a new gene family of nucleotide-binding proteins in eukaryotes

Nakashima, H., Grahovac, M. J., Mazzarella, R., Fujiwara, H., Kitchen, J. R., Threat, T. A. & Ko, M. S. H., 1999 Sep 1, In : Genomics. 60, 2, p. 152-160 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2000

A role for hematopoietic stem cells in promoting angiogenesis

Takakura, N., Watanabe, T., Suenobu, S., Yamada, Y., Noda, T., Ito, Y., Satake, M. & Suda, T., 2000 Jul 21, In : Cell. 102, 2, p. 199-209 11 p.

Research output: Contribution to journalArticle

Open Access
432 Citations (Scopus)

Bicarbonate transport in microperfused pancreatic ducts.

Ishiguro, H., Naruse, S., Kitagawa, M., Suzuki, A., Yamamoto, A., Ko, S. B., Hayakawa, T., Case, M. & Steward, M., 2000 Aug, In : Journal of Korean medical science. 15 Suppl, p. S16

Research output: Contribution to journalReview article

Open Access

Elevated levels of macrophage-stimulating protein in induced sputum of patients with bronchiectasis

Takano, Y., Sakamoto, O., Suga, M., Suda, T. & Ando, M., 2000, In : Respiratory Medicine. 94, 8, p. 784-790 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Eleven densely clustered genes, six of them novel, in 176 kb of mouse t-complex DNA

Kargul, G. J., Nagaraja, R., Shimada, T., Grahovac, M. J., Lim, M. K., Nakashima, H., Waeltz, P., Ma, P., Chen, E., Schlessinger, D. & Ko, M. S. H., 2000, In : Genome Research. 10, 7, p. 916-923 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tanaka, T. S., Jaradat, S. A., Lim, M. K., Kargul, G. J., Wang, X., Grahovac, M. J., Pantano, S., Sano, Y., Piao, Y., Nagaraja, R., Doi, H., Wood, W. H., Becker, K. G. & Ko, M. S. H., 2000 Aug 1, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 16, p. 9127-9132 6 p.

Research output: Contribution to journalArticle

354 Citations (Scopus)

Hematopoiesis and angiogenesis

Suda, T., 2000 Dec 1, In : International journal of hematology. 71, 2, p. 99-107 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver

Hsu, H. C., Ema, H., Osawa, M., Nakamura, Y., Suda, T. & Nakauchi, H., 2000 Dec 1, In : Blood. 96, 12, p. 3757-3762 6 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development

Ko, M. S. H., Kitchen, J. R., Wang, X., Threat, T. A., Wang, X., Hasegawa, A., Sun, T., Grahovac, M. J., Kargul, G. J., Lim, M. K., Cui, Y. S., Sano, Y., Tanaka, T., Liang, Y., Mason, S., Paonessa, P. D., Sauls, A. D., DePalma, G. E., Sharara, R., Rowe, L. B. & 3 others, Eppig, J., Morrell, C. & Doi, H., 2000 Apr, In : Development. 127, 8, p. 1737-1749 13 p.

Research output: Contribution to journalArticle

202 Citations (Scopus)

Serotonin and pancreatic duct function.

Naruse, S., Suzuki, A., Ishiguro, H., Kitagawa, M., Ko, S. B., Yoshikawa, T., Yamamoto, A., Hamada, H. & Hayakawa, T., 2000 Aug, In : Journal of Korean medical science. 15 Suppl, p. S27-28

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

The role of IL-18 on the pathogenesis of Crohn’s disease

Hibi, T., Kana, T., Watanabe, M., Okazawa, S. & Sato, T., 2000, In : Japanese Journal of Clinical Immunology. 23, 6, p. 607-610 4 p.

Research output: Contribution to journalArticle

Vegf-c signaling pathways through vegfr-2 and vegfr-3 in vasculo-angiogenesis and hematopoeesis

Hamada, K., Oike, Y., Takakura, N., Ito, Y., Jussila, L., Dumont, D. J., Alitalo, K. & Suda, T., 2000 Dec 1, In : Blood. 96, 11 PART I, p. 35a

Research output: Contribution to journalArticle

3 Citations (Scopus)

VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis

Hamada, K., Oike, Y., Takakura, N., Ito, Y., Jussila, L., Dumont, D. J., Alitalo, K. & Suda, T., 2000 Dec 1, In : Blood. 96, 12, p. 3793-3800 8 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)
2001

5-Hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells

Suzuki, A., Naruse, S., Kitagawa, M., Ishiguro, H., Yoshikawa, T., Ko, S. B. H., Yamamoto, A., Hamada, H. & Hayakawa, T., 2001, In : Journal of Clinical Investigation. 108, 5, p. 749-756 8 p.

Research output: Contribution to journalArticle

Open Access
45 Citations (Scopus)

A murine dopamine neuron-specific cDNA library and microarray: Increased COX1 expression during methamphetamine neurotoxicity

Barrett, T., Xie, T., Piao, Y., Dillon-Carter, O., Kargul, G. J., Lim, M. K., Chrest, F. J., Wersto, R., Rowley, D. L., Juhaszova, M., Zhou, L., Vawter, M. P., Becker, K. G., Cheadle, C., Wood, W. H., McCann, U. D., Freed, W. J., Ko, M. S., Ricaurte, G. A. & Donovan, D. M., 2001, In : Neurobiology of Disease. 8, 5, p. 822-833 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method

Piao, Y., Ko, N. T., Lim, M. K. & Ko, M. S. H., 2001, In : Genome Research. 11, 9, p. 1553-1558 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Endomucin is expressed in embryonic dorsal aorta and is able to inhibit cell adhesion

Ueno, M., Igarashi, K., Kimura, N., Okita, K., Takizawa, M., Nobuhisa, I., Kojima, T., Kitamura, T., Samulowitz, U., Vestweber, D., Shimomura, T., Suda, T., Nakashima, K. & Taga, T., 2001 Sep 21, In : Biochemical and Biophysical Research Communications. 287, 2, p. 501-506 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis

Yamada, Y., Takakura, N., Yasue, H., Ogawa, H., Fujisawa, H. & Suda, T., 2001 Mar 15, In : Blood. 97, 6, p. 1671-1678 8 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Expression of angiopoietin-2 in human glioma cells and its role for angiogenesis

Koga, K., Todaka, T., Morioka, M., Hamada, J. I., Kai, Y., Yano, S., Okamura, A., Ushio, Y., Takakura, N. & Suda, T., 2001 Aug 15, In : Cancer Research. 61, 16, p. 6248-6254 7 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Expression of discoidin domain receptor 1 tyrosine kinase on the human bronchial epithelium

Sakamoto, O., Suga, M., Suda, T. & Ando, M., 2001, In : European Respiratory Journal. 17, 5, p. 969-974 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Genetic mapping and functional studies of a natural inhibitor of the insulin receptor tyrosine kinase: the mouse ortholog of human alpha2-HS glycoprotein.

Cintrón, V. J., Ko, M. S., Chi, K. D., Gross, J. P., Srinivas, P. R., Goustin, A. S. & Grunberger, G., 2001, In : International journal of experimental diabetes research. 1, 4, p. 249-263 15 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Increased renal angiopoietin-1 expression in folic acid-induced nephrotoxicity in mice

Long, D. A., Woolf, A. S., Suda, T. & Yuan, H. T., 2001 Dec 17, In : Journal of the American Society of Nephrology. 12, 12, p. 2721-2731 11 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)