The Sakaguchi Laboratory

Research output

Research output per year 1979 2021

• 466 Article
• 41 Review article
• 14 Letter
• 10 Chapter
• 26 More
  • 10 Comment/debate
  • 7 Short survey
  • 5 Editorial
  • 4 Conference contribution

Research output per year

Research output per year

Search results

• 2004

  Dimer formation of receptor activator of nuclear factor κB induces incomplete osteoclast formation

  Iwamoto, K., Miyamoto, T., Sawatani, Y., Hosogane, N., Hamaguchi, I., Takami, M., Nomiyama, K., Takagi, K. & Suda, T., 2004 Dec 3, In: Biochemical and Biophysical Research Communications. 325, 1, p. 229-234 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Erythropoietin 100%
  • Osteoclasts 72%
  • Cytoplasmic and Nuclear Receptors 72%
  • AP20187 54%
  • Inducer 54%
  16 Citations (Scopus)

• Dynamic control of cystic fibrosis transmembrane conductance regulator Cl^-/HCO₃^- selectivity by external Cl ^-

  Shcheynikov, N., Kim, K. H., Kim, K. M., Dorwart, M. R., Ko, S. B. H., Goto, H., Naruse, S., Thomas, P. J. & Muallem, S., 2004 May 21, In: Journal of Biological Chemistry. 279, 21, p. 21857-21865 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystic Fibrosis Transmembrane Conductance Regulator 100%
  • Membrane Potential 86%
  • hydroxide ion 75%
  • Membrane Potentials 64%
  • Permeability 25%
  84 Citations (Scopus)

• Gating of CFTR by the STAS domain of SLC26 transporters

  Ko, S. B. H., Zeng, W., Dorwart, M. R., Luo, X., Kim, K. H., Millen, L., Goto, H., Naruse, S., Soyombo, A., Thomas, P. J. & Muallem, S., 2004 Apr, In: Nature Cell Biology. 6, 4, p. 343-350 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Bicarbonates 100%
  • Chlorides 97%
  • Cystic Fibrosis 59%
  • Chloride-Bicarbonate Antiporters 46%
  • Membranes 36%
  335 Citations (Scopus)

• Genetic evidence for CFTR dysfunction in Japanese: background for chronic pancreatitis.

  Fujiki, K., Ishiguro, H., Ko, S. B., Mizuno, N., Suzuki, Y., Takemura, T., Yamamoto, A., Yoshikawa, T., Kitagawa, M., Hayakawa, T., Sakai, Y., Takayama, T., Saito, M., Kondo, T. & Naruse, S., 2004 May, In: Journal of medical genetics. 41, 5, p. e55

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  38 Citations (Scopus)

• Hyperexpression of Inducible Costimulator and Its Contribution on Lamina Propria T Cells in Inflammatory Bowel Disease

  Sato, T., Kanai, T., Watanabe, M., Sakuraba, A., Okamoto, S., Nakai, T., Okazawa, A., Inoue, N., Totsuka, T., Yamazaki, M., Kroczek, R. A., Fukushima, T., Ishii, H. & Hibi, T., 2004 Mar, In: Gastroenterology. 126, 3, p. 829-839 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Inducible T-Cell Co-Stimulator Protein 100%
  • Inflammatory Bowel Diseases 57%
  • Mucous Membrane 48%
  • T-Lymphocytes 37%
  • Ulcerative Colitis 10%
  40 Citations (Scopus)

• Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

  Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T. & Nakayama, K. I., 2004 Mar 5, In: Journal of Biological Chemistry. 279, 10, p. 9417-9423 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Embryonic Structures 100%
  • F-Box Proteins 73%
  • Blood Vessels 71%
  • Protein 50%
  • Endothelial Cells 36%
  205 Citations (Scopus)

• Regulation of cell cycle in hematopoietic stem cells by the niche

  Hirao, A., Arai, F. & Suda, T., 2004 Dec, In: Cell Cycle. 3, 12, p. 1481-1483 3 p.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access

  • Stem Cell Niche 100%
  • Hematopoietic Stem Cells 76%
  • Cell Cycle 61%
  • Angiopoietin-1 21%
  • Side-Population Cells 11%
  31 Citations (Scopus)

• Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

  Ito, K., Hirao, A., Arai, F., Matsuoka, S., Takubo, K., Hamaguchi, I., Nomiyama, K., Hosokawa, K., Sakurada, K., Nakagata, N., Ikeda, Y., Mak, T. W. & Suda, T., 2004 Oct 21, In: Nature. 431, 7011, p. 997-1002 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Ataxia Telangiectasia 100%
  • Hematopoietic Stem Cells 77%
  • Oxidative Stress 57%
  • Bone Marrow Failure Disorders 35%
  • Reactive Oxygen Species 21%
  901 Citations (Scopus)

• T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction or Th1 mediated immunopathology in Crohn's disease

  Matsuoka, K., Inoue, N., Sato, T., Okamoto, S., Hisamatsu, T., Kishi, Y., Sakuraba, A., Hitotsumatsu, O., Ogata, H., Koganei, K., Fukushima, T., Kanai, T., Watanabe, M., Ishii, H. & Hibi, T., 2004 Sep, In: Gut. 53, 9, p. 1303-1308 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-12 100%
  • Crohn Disease 92%
  • Up-Regulation 70%
  • T-Lymphocytes 60%
  • Mucous Membrane 38%
  108 Citations (Scopus)
• 2003

  Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration

  Oike, Y., Yasunaga, K., Ito, Y., Matsumoto, S. I., Maekawa, H., Morisada, T., Arai, F., Nakagata, N., Takeya, M., Masuho, Y. & Suda, T., 2003 Aug 5, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 16, p. 9494-9499 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietins 100%
  • Mouse Angptl6 protein 92%
  • Epidermal Growth Factor 67%
  • Regeneration 58%
  • Intercellular Signaling Peptides and Proteins 48%
  87 Citations (Scopus)

• Defective smooth muscle development in qkl-deficient mice

  Li, Z., Takakura, N., Oike, Y., Imanaka, T., Araki, K., Suda, T., Kaname, T., Kondo, T., Abe, K. & Yamamura, K. I., 2003 Oct, In: Development Growth and Differentiation. 45, 5-6, p. 449-462 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Development 100%
  • Smooth Muscle Myocytes 75%
  • Smooth Muscle 75%
  • Yolk Sac 67%
  • Embryonic Structures 56%
  53 Citations (Scopus)

• Differentiation and function of osteoclasts

  Miyamoto, T. & Suda, T., 2003 Mar, In: Keio Journal of Medicine. 52, 1, p. 1-7 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Osteoclasts 100%
  • Bone and Bones 26%
  • Osteopetrosis 21%
  • RANK Ligand 19%
  • Osteogenesis 13%
  111 Citations (Scopus)

• Distinct roles of ephrin-B2 forward and EphB4 reverse signaling in endothelial cells

  Hamada, K., Oike, Y., Ito, Y., Maekawa, H., Miyata, K., Shimomura, T. & Suda, T., 2003 Feb 1, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 2, p. 190-197 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ephrin-B2 100%
  • Endothelial Cells 44%
  • Cell Adhesion 33%
  • EphB4 Receptor 22%
  • Cell Movement 19%
  75 Citations (Scopus)

• Ephrin-B2 Induces Migration of Endothelial Cells Through the Phosphatidylinositol-3 Kinase Pathway and Promotes Angiogenesis in Adult Vasculature

  Maekawa, H., Oike, Y., Kanda, S., Ito, Y., Yamada, Y., Kurihara, H., Nagai, R. & Suda, T., 2003 Nov, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 11, p. 2008-2014 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ephrin-B2 100%
  • Phosphatidylinositol 3-Kinase 60%
  • Endothelial Cells 44%
  • Human Umbilical Vein Endothelial Cells 31%
  • 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 14%
  68 Citations (Scopus)

• Ethanol induces fluid hypersecretion from guinea-pig pancreatic duct cells

  Yamamoto, A., Ishiguro, H., Ko, S. B. H., Suzuki, A., Wang, Y., Hamada, H., Mizuno, N., Kitagawa, M., Hayakawa, T. & Naruse, S., 2003 Sep 15, In: Journal of Physiology. 551, 3, p. 917-926 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Fluids and Secretions 100%
  • Pancreatic Ducts 99%
  • Secretin 77%
  • Guinea Pigs 75%
  • Ethanol 72%
  34 Citations (Scopus)

• Functional phenotype of phosphoinositide 3-kinase p85α-null platelets characterized by an impaired response to GP VI stimulation

  Watanabe, N., Nakajima, H., Suzuki, H., Oda, A., Matsubara, Y., Moroi, M., Terauchi, Y., Kadowaki, T., Suzuki, H., Koyasu, S., Ikeda, Y. & Handa, M., 2003 Jul 15, In: Blood. 102, 2, p. 541-548 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphoinositide 100%
  • Phosphatidylinositol 3-Kinase 74%
  • Glycoprotein 67%
  • Glycoproteins 62%
  • Blood Platelets 57%
  71 Citations (Scopus)

• Inhibition of Angiogenesis and Vascular Leakiness by Angiopoietin-Related Protein 4

  Ito, Y., Oike, Y., Yasunaga, K., Hamada, K., Miyata, K., Matsumoto, S. I., Sugano, S., Tanihara, H., Masuho, Y. & Suda, T., 2003 Oct 15, In: Cancer Research. 63, 20, p. 6651-6657 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietin-like 4 Protein 100%
  • Angiopoietins 81%
  • Angiopoietin-like Proteins 47%
  • Psychological Inhibition 46%
  • Corneal Neovascularization 40%
  144 Citations (Scopus)

• Neuropilin-1 on hematopoietic cells as a source of vascular development

  Yamada, Y., Oike, Y., Ogawa, H., Ito, Y., Fujisawa, H., Suda, T. & Takakura, N., 2003 Mar 1, In: Blood. 101, 5, p. 1801-1809 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuropilin-1 100%
  • Blood Vessels 39%
  • Dimerization 30%
  • human VEGFA protein 29%
  • Vascular Endothelial Growth Factor Receptor 15%
  37 Citations (Scopus)

• The expression of platelet endothelial cell adhesion molecule-1 in mouse primordial germ cells during their migration and early gonadal formation

  Wakayama, T., Hamada, K., Yamamoto, M., Suda, T. & Iseki, S., 2003 May 1, In: Histochemistry and Cell Biology. 119, 5, p. 355-362 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mouse Pecam1 protein 100%
  • Platelet Endothelial Cell Adhesion Molecule-1 67%
  • Germ Cells 47%
  • Gonads 18%
  • Alkaline Phosphatase 14%
  26 Citations (Scopus)
• 2002

  AE4 is a DIDS-sensitive Cl^-/HCO₃^- exchanger in the basolateral membrane of the renal CCD and the SMG duct

  Ko, S. B. H., Luo, X., Hager, H., Rojek, A., Choi, J. Y., Licht, C., Suzuki, M., Muallem, S., Nielsen, S. & Ishibashi, K., 2002 Oct, In: American Journal of Physiology - Cell Physiology. 283, 4 52-4, p. C1206-C1218

  Research output: Contribution to journal › Article › peer-review

  • Chloride-Bicarbonate Antiporters 100%
  • 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid 95%
  • Protein Isoforms 53%
  • Membranes 39%
  • Kidney 35%
  89 Citations (Scopus)

• A molecular mechanism for aberrant CFTR-dependent HCO₃^- transport in cystic fibrosis

  Ko, S. B. H., Shcheynikov, N., Choi, J. Y., Luo, X., Ishibashi, K., Thomas, P. J., Kim, J. Y., Kim, K. H., Lee, M. G., Naruse, S. & Muallem, S., 2002 Nov 1, In: EMBO Journal. 21, 21, p. 5662-5672 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystic Fibrosis Transmembrane Conductance Regulator 100%
  • Cystic Fibrosis 77%
  • Conductance 75%
  • Reaction Stoichiometry 18%
  • Congenital chloride diarrhea 18%
  267 Citations (Scopus)

• Aquaporins in rat pancreatic interlobular ducts

  Ko, S. B. H., Naruse, S., Kitagawa, M., Ishiguro, H., Furuya, S., Mizuno, N., Wang, Y., Yoshikawa, T., Suzuki, A., Shimano, S. & Hayakawa, T., 2002, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 282, 2 45-2, p. G324-G331

  Research output: Contribution to journal › Article › peer-review

  • Aquaporins 100%
  • Pancreatic Ducts 89%
  • Mercuric Chloride 53%
  • Water 51%
  • Epithelium 29%
  44 Citations (Scopus)

• A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis

  Suenobu, S., Takakura, N., Inada, T., Yamada, Y., Yuasa, H., Zhang, X. Q., Sakano, S., Oike, Y. & Suda, T., 2002, In: Biochemical and Biophysical Research Communications. 293, 3, p. 1124-1131 8 p.

  Research output: Contribution to journal › Article › peer-review

  • EphB4 Receptor 100%
  • Ephrin-B2 89%
  • Erythropoietin 75%
  • Cord 65%
  • Erythropoiesis 62%
  48 Citations (Scopus)

• Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

  Hirao, A., Cheung, A., Duncan, G., Girard, P. M., Elia, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., De Stanchina, E., Bristow, R. G., Suda, T., Lowe, S. W., Jeggo, P. A., Elledge, S. J. & Mak, T. W., 2002 Sep, In: Molecular and cellular biology. 22, 18, p. 6521-6532 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Ataxia Telangiectasia 100%
  • Ionizing Radiation 50%
  • Apoptosis 48%
  • Neoplasms 25%
  • Thymocytes 21%
  307 Citations (Scopus)

• Differentiation of trophoblast lineage is associated with DNA methylation and demethylation

  Ohgane, J., Hattori, N., Oda, M., Tanaka, S. & Shiota, K., 2002 Jan 18, In: Biochemical and Biophysical Research Communications. 290, 2, p. 701-706 6 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Demethylation 100%
  • Demethylation 83%
  • Trophoblasts 76%
  • Giant Cells 75%
  • DNA Methylation 69%
  39 Citations (Scopus)

• Effect of direct angiogenesis inhibition in rheumatoid arthritis using a soluble vascular endothelial growth factor receptor 1 chimeric protein

  Sekimoto, T., Hamada, K., Oike, Y., Matsuoka, T., Matsumoto, M., Chosa, E., Suda, T., Tajima, N. & Yamamura, K. I., 2002 Feb 12, In: Journal of Rheumatology. 29, 2, p. 240-245 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Endothelial Growth Factor Receptor-1 100%
  • Rheumatoid Arthritis 62%
  • Synovial Membrane 29%
  • Proteins 27%
  • human FLT1 protein 24%
  24 Citations (Scopus)

• Expression and function of NJ-1 surface antigen in megakaryopoiesis

  Tang, H., Zhang, X. Q., Naruse, T., Ohbo, K. & Suda, T., 2002 Jan 1, In: Biochemical and Biophysical Research Communications. 292, 3, p. 667-674 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Megakaryocytes 100%
  • Surface Antigens 87%
  • Antigen 69%
  • Protein 34%
  • Molecule 28%

• Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells

  Burger, P. E., Coetzee, S., McKeehan, W. L., Kan, M., Cook, P., Fan, Y., Suda, T., Hebbel, R. P., Novitzky, N., Muller, W. A. & Lynette Wilson, E., 2002 Nov 15, In: Blood. 100, 10, p. 3527-3535 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Fibroblast Growth Factor, Type 1 100%
  • Endothelial Progenitor Cells 83%
  • Marker 59%
  • Antigen 38%
  • Endothelial Cells 37%
  85 Citations (Scopus)

• Mechanism of hypercalcemia in adult T-cell leukemia: Overexpression of receptor activator of nuclear factor κb ligand on adult T-cell leukemia cells

  Nosaka, K., Miyamoto, T., Sakai, T., Mitsuya, H., Suda, T. & Matsuoka, M., 2002 Jan 15, In: Blood. 99, 2, p. 634-640 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypercalcemic 100%
  • RANK Ligand 80%
  • Adult T Cell Leukemia Lymphoma 77%
  • Hypercalcemia 66%
  • Cytoplasmic and Nuclear Receptors 61%
  126 Citations (Scopus)

• Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation

  Arai, F., Ohneda, O., Miyamoto, T., Zhang, X. Q. & Suda, T., 2002 Jun 17, In: Journal of Experimental Medicine. 195, 12, p. 1549-1563 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Activated-Leukocyte Cell Adhesion Molecule 100%
  • Mesenchymal Stem Cells 53%
  • Osteogenesis 52%
  • Bone Marrow 43%
  • Metatarsal Bones 7%
  178 Citations (Scopus)

• Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes

  Mera, A., Suga, M., Nakayama, Y., Ando, M., Suda, T. & Yamaguchi, N., 2002 Nov 1, In: Immunology Letters. 84, 2, p. 117-124 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Shape 100%
  • Interleukin-3 99%
  • macrophage stimulating protein 98%
  • Mitogen-Activated Protein Kinase Kinases 92%
  • Phosphotransferases 51%
  6 Citations (Scopus)

• Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells

  Oike, Y., Ito, Y., Hamada, K., Zhang, X. Q., Miyata, K., Arai, F., Inada, T., Araki, K., Nakagata, N., Takeya, M., Kisanuki, Y. Y., Yanagisawa, M., Gale, N. W. & Suda, T., 2002 Aug 15, In: Blood. 100, 4, p. 1326-1333 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ephrin-B2 100%
  • Tyrosine 54%
  • Endothelial Cells 44%
  • Repellent 38%
  • Eph Family Receptors 17%
  106 Citations (Scopus)

• The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO₃^- salvage transporter human Na⁺-HCO₃^- cotransport isoform 3

  Park, M., Ko, S. B. H., Choi, J. Y., Muallem, G., Thomas, P. J., Pushkin, A., Lee, M. S., Kim, J. Y., Lee, M. G., Muallem, S. & Kurtz, I., 2002 Dec 27, In: Journal of Biological Chemistry. 277, 52, p. 50503-50509 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystic Fibrosis Transmembrane Conductance Regulator 100%
  • Protein Isoforms 64%
  • Submandibular Gland 17%
  • Pancreas 12%
  • ethylisopropylamiloride 11%
  78 Citations (Scopus)
• 2001

  5-Hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells

  Suzuki, A., Naruse, S., Kitagawa, M., Ishiguro, H., Yoshikawa, T., Ko, S. B. H., Yamamoto, A., Hamada, H. & Hayakawa, T., 2001, In: Journal of Clinical Investigation. 108, 5, p. 749-756 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fluids and Secretions 100%
  • Pancreatic Ducts 84%
  • Guinea Pigs 65%
  • Serotonin 63%
  • Secretin 51%
  45 Citations (Scopus)

• ALCAM (CD166): Its role in hematopoietic and endothelial development

  Ohneda, O., Ohneda, K., Arai, F., Lee, J., Miyamoto, T., Fukushima, Y., Dowbenko, D., Lasky, L. A. & Suda, T., 2001 Oct 1, In: Blood. 98, 7, p. 2134-2142 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Activated-Leukocyte Cell Adhesion Molecule 100%
  • Capillary Tube 79%
  • Hematopoiesis 37%
  • Yolk Sac 33%
  • Aorta 29%
  118 Citations (Scopus)

• Bifurcation of osteoclasts and dendritic cells from common progenitors

  Miyamoto, T., Ohneda, O., Arai, F., Iwamoto, K., Okada, S., Takagi, K., Anderson, D. M. & Suda, T., 2001 Oct 15, In: Blood. 98, 8, p. 2544-2554 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Colony Stimulating Factor 100%
  • Granulocyte-Macrophage Colony-Stimulating Factor 70%
  • Osteoclasts 69%
  • Dendritic Cells 59%
  • Macrophage Colony-Stimulating Factor 27%
  219 Citations (Scopus)

• Endomucin is expressed in embryonic dorsal aorta and is able to inhibit cell adhesion

  Ueno, M., Igarashi, K., Kimura, N., Okita, K., Takizawa, M., Nobuhisa, I., Kojima, T., Kitamura, T., Samulowitz, U., Vestweber, D., Shimomura, T., Suda, T., Nakashima, K. & Taga, T., 2001 Sep 21, In: Biochemical and Biophysical Research Communications. 287, 2, p. 501-506 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Sialomucins 100%
  • Complementary DNA 66%
  • Cell Adhesion 59%
  • Aorta 55%
  • Endothelial Cells 35%
  7 Citations (Scopus)

• Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis

  Yamada, Y., Takakura, N., Yasue, H., Ogawa, H., Fujisawa, H. & Suda, T., 2001 Mar 15, In: Blood. 97, 6, p. 1671-1678 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuropilin-1 100%
  • human VEGFA protein 31%
  • Blood Vessels 26%
  • Mesoderm 24%
  • Vascular Endothelial Growth Factor Receptor 20%
  56 Citations (Scopus)

• Expression of angiopoietin-2 in human glioma cells and its role for angiogenesis

  Koga, K., Todaka, T., Morioka, M., Hamada, J. I., Kai, Y., Yano, S., Okamura, A., Ushio, Y., Takakura, N. & Suda, T., 2001 Aug 15, In: Cancer Research. 61, 16, p. 6248-6254 7 p.

  Research output: Contribution to journal › Article › peer-review

  • human ANGPT2 protein 100%
  • Glioma 46%
  • Angiogenesis Inducing Agents 14%
  • Astrocytoma 13%
  • Glioblastoma 8%
  133 Citations (Scopus)

• Expression of discoidin domain receptor 1 tyrosine kinase on the human bronchial epithelium

  Sakamoto, O., Suga, M., Suda, T. & Ando, M., 2001, In: European Respiratory Journal. 17, 5, p. 969-974 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Discoidin Domain Receptor 1 100%
  • Epithelium 43%
  • Collagen Type IV 18%
  • Epithelial Cells 14%
  • Collagen 11%
  28 Citations (Scopus)

• HCO₃^- Salvage Mechanisms in the Submandibular Gland Acinar and Duct Cells

  Luo, X., Choi, J. Y., Ko, S. B. H., Pushkin, A., Kurtz, I., Ahn, W., Lee, M. G. & Muallem, S., 2001 Mar 30, In: Journal of Biological Chemistry. 276, 13, p. 9808-9816 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Submandibular Gland 100%
  • Acinar Cells 99%
  • Amiloride 87%
  • Acids 63%
  • hydroxide ion 40%
  68 Citations (Scopus)

• Increased renal angiopoietin-1 expression in folic acid-induced nephrotoxicity in mice

  Long, D. A., Woolf, A. S., Suda, T. & Yuan, H. T., 2001 Dec 17, In: Journal of the American Society of Nephrology. 12, 12, p. 2721-2731 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietin-1 100%
  • Folic Acid 70%
  • Capillaries 41%
  • Kidney 37%
  • Coloring Agents 23%
  53 Citations (Scopus)

• In early development of the rat mRNA for the major myelin protein P₀ is expressed in nonsensory areas of the embryonic inner ear, notochord, enteric nervous system, and olfactory ensheathing cells

  Kolatsi-Joannou, M., Li, X. Z., Suda, T., Yuan, H. T. & Woolf, A. S., 2001, In: Developmental Dynamics. 222, 1, p. 40-51 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Myelin P0 Protein 100%
  • Notochord 87%
  • Enteric Nervous System 84%
  • Inner Ear 68%
  • Messenger RNA 36%
  42 Citations (Scopus)

• Insulinoma with Subsequent Association of Zollinger-Ellison Syndrome

  Mizuno, N., Naruse, S., Kitagawa, M., Ishiguro, H., Ito, O., Ko, S. B. H., Yoshikawa, T., Tanahashi, C., Ito, M. & Hayakawa, T., 2001 May, In: Internal Medicine. 40, 5, p. 386-390 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zollinger-Ellison Syndrome 100%
  • Insulinoma 86%
  • Gastrins 53%
  • gastrin I 40%
  • Acinar Cell Carcinoma 33%
  7 Citations (Scopus)

• Interleukin-18 and Crohn's disease

  Kanai, T., Watanabe, M., Okazawa, A., Sato, T. & Hibi, T., 2001 Feb 6, In: Digestion. 63, SUPPL. 1, p. 37-42 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-18 100%
  • Crohn Disease 81%
  • Macrophages 29%
  • T-Lymphocytes 26%
  • Intestinal Mucosa 22%
  28 Citations (Scopus)

• Localization of recombination activating gene 1/green fluorescent protein (RAG1/GFP) expression in secondary lymphoid organs after immunization with T-dependent antigens in rag1/gfp knockin mice

  Igarashi, H., Kuwata, N., Kiyota, K., Sumita, K., Suda, T., Ono, S., Bauer, S. R. & Sakaguchi, N., 2001 May 1, In: Blood. 97, 9, p. 2680-2687 8 p.

  Research output: Contribution to journal › Article › peer-review

  • RAG-1 Genes 100%
  • Green Fluorescent Proteins 64%
  • Immunization 50%
  • Antigen 50%
  • Germinal Center 47%
  37 Citations (Scopus)

• Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn’s disease

  Kanai, T., Watanabe, M., Okazawa, A., Sato, T., Yamazaki, M., Okamoto, S., Ishii, H., Totsuka, T., Iiyama, R., Okamoto, R., Ikeda, M., Kurimoto, M., Takeda, K., Akira, S. & Hibi, T., 2001, In: Gastroenterology. 121, 4, p. 875-888 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-18 100%
  • Crohn Disease 81%
  • Sulfonic Acids 75%
  • Trinitrobenzenes 70%
  • Macrophages 59%
  156 Citations (Scopus)

• Organization of the chemokine genes in the human and mouse major clusters of CC and CXC chemokines: Diversification between the two species

  Nomiyama, H., Mera, A., Ohneda, O., Miura, R., Suda, T. & Yoshie, O., 2001 Apr, In: Genes and Immunity. 2, 2, p. 110-113 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • CXC Chemokines 100%
  • CC Chemokines 98%
  • Chemokines 73%
  • Organizations 65%
  • Multigene Family 33%
  34 Citations (Scopus)

• Overexpression of the Csk homologous kinase (Chk tyrosine kinase) induces multinucleation: A possible role for chromosome-associated Chk in chromosome dynamics

  Yamaguchi, N., Nakayama, Y., Urakami, T., Suzuki, S., Nakamura, T., Suda, T. & Oku, N., 2001 May 30, In: Journal of Cell Science. 114, 9, p. 1631-1641 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Tyrosine 100%
  • Protein-Tyrosine Kinases 98%
  • Chromosomes 85%
  • Phosphotransferases 83%
  • Spindle Apparatus 67%
  49 Citations (Scopus)

• PAL31 expression in rat trophoblast giant cells

  Oda, M., Sun, W., Hattori, N., Tanaka, S. & Shiota, K., 2001 Sep 28, In: Biochemical and Biophysical Research Communications. 287, 3, p. 721-726 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Trophoblasts 100%
  • Giant Cells 98%
  • Endoreduplication 72%
  • Subcellular Localization 62%
  • Cell Cycle 54%
  6 Citations (Scopus)