The Sakaguchi Laboratory

Research Output

Article

[Regulation of hematopoietic stem cells in niche signaling].

Matsumoto, Y. & Suda, T., 2012 Apr, In : Nihon rinsho. Japanese journal of clinical medicine. 70 Suppl 2, p. 133-138 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

5-Hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells

Suzuki, A., Naruse, S., Kitagawa, M., Ishiguro, H., Yoshikawa, T., Ko, S. B. H., Yamamoto, A., Hamada, H. & Hayakawa, T., 2001 Jan 1, In : Journal of Clinical Investigation. 108, 5, p. 749-756 8 p.

Research output: Contribution to journalArticle

Open Access
45 Citations (Scopus)

Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

Kamada, N., Hisamatsu, T., Okamoto, S., Sato, T., Matsuoka, K., Arai, K., Nakai, T., Hasegawa, A., Inoue, N., Watanabe, N., Akagawa, K. S. & Hibi, T., 2005 Nov 15, In : Journal of Immunology. 175, 10, p. 6900-6908 9 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

A case of acute promyelocytic leukemia (APL) with myeloblastoma in the oral cavity developing after receiving all-trans retinoic acid (ATRA)

Izumi, T., Hatake, K., Imagawa, S., Yoshikda, M., Ohta, M., Sasaki, R., Miwa, A., Suda, T., Sakamoto, S. & Miura, Y., 1994 Jun, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 35, 6, p. 598-602 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A case of lung cancer associated with granulocytosis and production of colony-stimulating activity by the tumour

Suda, T., Miura, Y., Mizoguchi, H., Kubota, K. & Takaku, F., 1980 Jun, In : British Journal of Cancer. 41, 6, p. 980-984 5 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

Fujii, M., Shimokawa, M., Date, S., Takano, A., Matano, M., Nanki, K., Ohta, Y., Toshimitsu, K., Nakazato, Y., Kawasaki, K., Uraoka, T., Watanabe, T., Kanai, T. & Sato, T., 2016 Jun 2, In : Cell Stem Cell. 18, 6, p. 827-838 12 p.

Research output: Contribution to journalArticle

190 Citations (Scopus)

A common signaling pathway via Syk and Lyn tyrosine kinases generated from capping of the sialomucins CD34 and CD43 in immature hematopoietic cells

Tada, J. I., Omine, M., Suda, T. & Yamaguchi, N., 1999 Jun 1, In : Blood. 93, 11, p. 3723-3735 13 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance

Livigni, A., Peradziryi, H., Sharov, A. A., Chia, G., Hammachi, F., Migueles, R. P., Sukparangsi, W., Pernagallo, S., Bradley, M., Nichols, J., Ko, M. S. H. & Brickman, J. M., 2013 Nov 18, In : Current Biology. 23, 22, p. 2233-2244 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function

Nagamachi, A., Nakata, Y., Ueda, T., Yamasaki, N., Ebihara, Y., Tsuji, K., Honda, Z. I., Takubo, K., Suda, T., Oda, H., Inaba, T. & Honda, H., 2014 Jan 31, In : PloS one. 9, 1, e87425.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo

Uchiba, M., Okajima, K., Oike, Y., Ito, Y., Fukudome, K., Isobe, H. & Suda, T., 2004 Jul 9, In : Circulation research. 95, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress

Nishiyama, A., Dey, A., Tamura, T., Ko, M. & Ozato, K., 2012 May 2, In : PloS one. 7, 5, e34719.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Active and water-soluble form of lipidated wnt protein is maintained by a serum glycoprotein afamin/α-albumin

Mihara, E., Hirai, H., Yamamoto, H., Tamura-Kawakami, K., Matano, M., Kikuchi, A., Sato, T. & Takagi, J., 2016 Feb 23, In : eLife. 5, FEBRUARY2016, e11621.

Research output: Contribution to journalArticle

52 Citations (Scopus)

A CTX family cell adhesion molecule, JAM4, is expressed in stem cell and progenitor cell populations of both male germ cell and hematopoietic cell lineages

Nagamatsu, G., Ohmura, M., Mizukami, T., Hamaguchi, I., Hirabayashi, S., Yoshida, S., Hata, Y., Suda, T. & Ohbo, K., 2006 Nov 1, In : Molecular and cellular biology. 26, 22, p. 8498-8506 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Acute Idiopathic Polyneuritis with Ophthalmoplegia, Ataxia, and Areflexia (Fisher's Syndrome). A Case Report and a Review of the Literature

Suda, T., Nihei, K. & Kamoshita, S., 1979 Jan 1, In : NO TO HATTATSU. 11, 4, p. 321-327 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Adverse events in patients with ulcerative colitis treated with indigo naturalis: a Japanese nationwide survey

INDIGO survey Group, 2019 Oct 1, In : Journal of gastroenterology. 54, 10, p. 891-896 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

AE4 is a DIDS-sensitive Cl-/HCO3- exchanger in the basolateral membrane of the renal CCD and the SMG duct

Ko, S. B. H., Luo, X., Hager, H., Rojek, A., Choi, J. Y., Licht, C., Suzuki, M., Muallem, S., Nielsen, S. & Ishibashi, K., 2002 Oct, In : American Journal of Physiology - Cell Physiology. 283, 4 52-4, p. C1206-C1218

Research output: Contribution to journalArticle

88 Citations (Scopus)

A finger sweat chloride test for the detection of a high-risk group of chronic pancreatitis

Naruse, S., Ishiguro, H., Suzuki, Y., Fujiki, K., Ko, S. B. H., Mizuno, N., Takemura, T., Yamamoto, A., Yoshikawa, T., Jin, C., Suzuki, R., Kitagawa, M., Tsuda, T., Kondo, T. & Hayakawa, T., 2004 Mar, In : Pancreas. 28, 3, p. e80-e85

Research output: Contribution to journalArticle

14 Citations (Scopus)

Aging and cancer in hematopoietic stem cells

Nitta, E. & Suda, T., 2009 May 1, In : Japanese Journal of Geriatrics. 46, 3, p. 195-199 5 p.

Research output: Contribution to journalArticle

A Highly Inducible System of Gene Expression by Positive Feedback Production of Glucocorticoid Receptors

Ko, M. S. H. & Takano, T., 1989 Mar, In : DNA. 8, 2, p. 127-133 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 I. Concept and diagnosis of autoimmune pancreatitis

Okazaki, K., Kawa, S., Kamisawa, T., Ito, T., Inui, K., Irie, H., Nishino, T., Notohara, K., Nishimori, I., Tanaka, S., Nishiyama, T., Suda, K., Shiratori, K., Tanaka, M., Shimosegawa, T., Kubo, K., Ohara, H., Irisawa, A., Fujinaga, Y., Hasebe, O. & 19 others, Yamamoto, H., Uchida, K., Kanno, A., Kubota, K., Ko, S., Sakagami, J., Shimizu, K., Sugiyama, M., Tada, M., Nakazawa, T., Nishino, H., Hamano, H., Hirooka, Y., Hirano, K., Masamune, A., Masuda, A., Mizuno, N., Yamaguchi, K. & Yoshida, H., 2014 Apr, In : Journal of gastroenterology. 49, 4, p. 567-588 22 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 II. Extrapancreatic lesions, differential diagnosis

Kawa, S., Okazaki, K., Kamisawa, T., Kubo, K., Ohara, H., Hasebe, O., Fujinaga, Y., Irisawa, A., Notohara, K., Ito, T., Inui, K., Irie, H., Nishino, T., Nishimori, I., Tanaka, S., Nishiyama, T., Suda, K., Shiratori, K., Tanaka, M., Shimosegawa, T. & 19 others, Yamamoto, H., Uchida, K., Kanno, A., Kubota, K., Ko, S., Sakagami, J., Shimizu, K., Sugiyama, M., Tada, M., Nakazawa, T., Nishino, H., Hamano, H., Hirooka, Y., Hirano, K., Masamune, A., Masuda, A., Mizuno, N., Yamaguchi, K. & Yoshida, H., 2014 May, In : Journal of gastroenterology. 49, 5, p. 765-784 20 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis

Kamisawa, T., Okazaki, K., Kawa, S., Ito, T., Inui, K., Irie, H., Nishino, T., Notohara, K., Nishimori, I., Tanaka, S., Nishiyama, T., Suda, K., Shiratori, K., Tanaka, M., Shimosegawa, T., Kubo, K., Ohara, H., Irisawa, A., Fujinaga, Y., Hasebe, O. & 19 others, Yamamoto, H., Uchida, K., Kanno, A., Kubota, K., Ko, S., Sakagami, J., Shimizu, K., Sugiyama, M., Tada, M., Nakazawa, T., Nishino, H., Hamano, H., Hirooka, Y., Hirano, K., Masamune, A., Masuda, A., Mizuno, N., Yamaguchi, K. & Yoshida, H., 2014 Jun, In : Journal of gastroenterology. 49, 6, p. 961-970 10 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

Analysis of C-KIT, TIE and HTK expression on leukemic cells using flow cytometry: A preliminary report

Muroi, K., Suda, T., Kawano, C., Amemiya, Y., Eguchi, M., Miura, Y. & Ozawa, K., 1998 Sep 1, In : Leukemia Research. 22, 9, p. 827-830 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Analysis of CSK homologous kinase (CHK/HYL) in hematopoiesis by utilizing gene knockout mice

Hamaguchi, I., Yamaguchi, N., Suda, J., Iwama, A., Hirao, A., Hashiyama, M., Aizawa, S. I. & Suda, T., 1996 Jul 5, In : Biochemical and Biophysical Research Communications. 224, 1, p. 172-179 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Analysis of eosinophil-predominant colonies formed by human hemopoietic precursor cells in the presence of purified interleukin-5

Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Mita Hitoshi, S. Y., Tominaga, A. & Takatsu, K., 1990 Jan 1, In : Acta Haematologica Japonica. 53, 4, p. 688-698 11 p.

Research output: Contribution to journalArticle

Analysis of human TIE2 function on hematopoietic stem cells in umbilical cord blood

Yuasa, H., Takakura, N., Shimomura, T., Suenobu, S., Yamada, T., Nagayama, H., Oike, Y. & Suda, T., 2002 Nov 30, In : Biochemical and Biophysical Research Communications. 298, 5, p. 731-737 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Analysis of the survival of mature human eosinophils: Interleukin-5 prevents apoptosis in mature human eosinophils

Yamaguchi, Y., Suda, T., Ohta, S., Tominaga, K., Miura, Y. & Kasahara, T., 1991 Jan 1, In : Blood. 78, 10, p. 2542-2547 6 p.

Research output: Contribution to journalArticle

Open Access
255 Citations (Scopus)

An auto-inducible vector conferring high glucocorticoid inducibility upon stable transformant cells

Ko, M. S. H., Naomi, T., Norifumi, S. & Toshiya, T., 1989 Dec 14, In : Gene. 84, 2, p. 383-389 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

An Autopsy Case of Reye Syndrome during a Remission of Malignant Lymphoma

Hamano, Y., Suda, T., Kamoshita, S. & Koike, M., 1983 Jan, In : NO TO HATTATSU. 15, 5, p. 438-444 7 p.

Research output: Contribution to journalArticle

An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity

Shirakawa, T., Yaman-Deveci, R., Tomizawa, S. I., Kamizato, Y., Nakajima, K., Sone, H., Sato, Y., Sharif, J., Yamashita, A., Takada-Horisawa, Y., Yoshida, S., Ura, K., Muto, M., Koseki, H., Suda, T. & Ohbo, K., 2013 Sep 1, In : Development (Cambridge). 140, 17, p. 3565-3576 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

A new hematopoietic cell line, KMT-2, having human interleukin-3 receptors

Tamura, S., Sugawara, M., Tanaka, H., Tezuka, E., Nihira, S., Miyamoto, C., Suda, T. & Ohta, Y., 1990 Jan 1, In : Blood. 76, 3, p. 501-507 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy

Lee, J., Kim, K. E., Choi, D. K., Jang, J. Y., Jung, J. J., Kiyonari, H., Shioi, G., Chang, W., Suda, T., Mochizuki, N., Nakaoka, Y., Komuro, I., Yoo, O. J. & Koh, G. Y., 2013 Sep 18, In : Science translational medicine. 5, 203, 203ra127.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis

Adachi, H., Fujiwara, Y., Kondo, T., Nishikawa, T., Ogawa, R., Matsumura, T., Ishii, N., Nagai, R., Miyata, K., Tabata, M., Motoshima, H., Furukawa, N., Tsuruzoe, K., Kawashima, J., Takeya, M., Yamashita, S., Koh, G. Y., Nagy, A., Suda, T., Oike, Y. & 1 others, Araki, E., 2009 Feb 20, In : Biochemical and Biophysical Research Communications. 379, 4, p. 806-811 6 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium

Pin, C., Parker, A., Gunning, A. P., Ohta, Y., Johnson, I. T., Carding, S. R. & Sato, T., 2015 Feb 1, In : Integrative Biology (United Kingdom). 7, 2, p. 213-228 16 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Antibacterial activity of highly negative charged polyoxotungstates, K 27[KAs4W40O140] and K 18[KSb9W21O86], and Keggin-structural polyoxotungstates against Helicobacter pylori

Inoue, M., Segawa, K., Matsunaga, S., Matsumoto, N., Oda, M. & Yamase, T., 2005 May, In : Journal of Inorganic Biochemistry. 99, 5, p. 1023-1031 9 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

A pilot open-labeled prospective randomized study between weekly and intensive treatment of granulocyte and monocyte adsorption apheresis for active ulcerative colitis

Sakuraba, A., Sato, T., Naganuma, M., Morohoshi, Y., Matsuoka, K., Inoue, N., Takaishi, H., Ogata, H., Iwao, Y. & Hibi, T., 2008 Jan 1, In : Journal of gastroenterology. 43, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

A PML-PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

Ito, K., Carracedo, A., Weiss, D., Arai, F., Ala, U., Avigan, D. E., Schafer, Z. T., Evans, R. M., Suda, T., Lee, C. H. & Pandolfi, P. P., 2012 Sep 1, In : Nature medicine. 18, 9, p. 1350-1358 9 p.

Research output: Contribution to journalArticle

327 Citations (Scopus)

A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells

Azuma, M., Hirao, A., Takubo, K., Hamaguchi, I., Kitamura, T. & Suda, T., 2005 Dec 16, In : Biochemical and Biophysical Research Communications. 338, 2, p. 1164-1170 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Aquaporin 1 water channel is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune pancreatitis

Ko, S. B. H., Mizuno, N., Yatabe, Y., Yoshikawa, T., Ishiguro, H., Yamamoto, A., Azuma, S., Naruse, S., Yamao, K., Muallem, S. & Goto, H., 2009 Dec 1, In : Journal of Medical Investigation. 56, SUPPL. 1, p. 318-321 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Aquaporins in rat pancreatic interlobular ducts

Ko, S. B. H., Naruse, S., Kitagawa, M., Ishiguro, H., Furuya, S., Mizuno, N., Wang, Y., Yoshikawa, T., Suzuki, A., Shimano, S. & Hayakawa, T., 2002 Jun 27, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 282, 2 45-2, p. G324-G331

Research output: Contribution to journalArticle

42 Citations (Scopus)

A recombinant murine granulocyte/macrophage (GM) colony-stimulating factor derived from an inducer T cell line (IH5.5): Functional restriction to GM progenitor cells

Kajigaya, S., Suda, T., Suda, J., Saito, M., Miura, Y., Iizuka, M., Kobayashi, S., Minato, N. & Sudo, T., 1986 Oct 1, In : Journal of Experimental Medicine. 164, 4, p. 1102-1113 12 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

A role for borg5 during trophectoderm differentiation.

Vong, Q. P., Liu, Z., Yoo, J. G., Chen, R., Xie, W., Sharov, A. A., Fan, C. M., Liu, C., Ko, M. S. H. & Zheng, Y., 2010 Jun, In : Stem cells (Dayton, Ohio). 28, 6, p. 1030-1038 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A role for hematopoietic stem cells in promoting angiogenesis

Takakura, N., Watanabe, T., Suenobu, S., Yamada, Y., Noda, T., Ito, Y., Satake, M. & Suda, T., 2000 Jul 21, In : Cell. 102, 2, p. 199-209 11 p.

Research output: Contribution to journalArticle

Open Access
431 Citations (Scopus)

A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis

Suenobu, S., Takakura, N., Inada, T., Yamada, Y., Yuasa, H., Zhang, X. Q., Sakano, S., Oike, Y. & Suda, T., 2002 Jan 1, In : Biochemical and Biophysical Research Communications. 293, 3, p. 1124-1131 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Asian diagnostic criteria for autoimmune pancreatitis: Consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis

Otsuki, M., Chung, J. B., Okazaki, K., Kim, M. H., Kamisawa, T., Kawa, S., Park, S. W., Shimosegawa, T., Lee, K., Ito, T., Nishimori, I., Notohara, K., Naruse, S., Ko, S. B. H. & Kihara, Y., 2008 Jun 1, In : Journal of gastroenterology. 43, 6, p. 403-408 6 p.

Research output: Contribution to journalArticle

361 Citations (Scopus)

A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice

Hayashi, A., Sato, T., Kamada, N., Mikami, Y., Matsuoka, K., Hisamatsu, T., Hibi, T., Roers, A., Yagita, H., Ohteki, T., Yoshimura, A. & Kanai, T., 2013 Jun 12, In : Cell Host and Microbe. 13, 6, p. 711-722 12 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1α

Suda, T., Okada, S., Suda, J., Miura, Y., Ito, M., Sudo, T., Hayashi, S. I., Nishikawa, S. I. & Nakauchi, H., 1989 Jan 1, In : Blood. 74, 6, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

A systematic molecular genetic approach to study mammalian germline development

Abe, K., Ko, M. S. H. & Macgregor, G. R., 1998 Dec 2, In : International Journal of Developmental Biology. 42, 7, p. 1051-1065 15 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Bicarbonate-rich fluid secretion predicted by a computational model of guinea-pig pancreatic duct epithelium

Yamaguchi, M., Steward, M. C., Smallbone, K., Sohma, Y., Yamamoto, A., Ko, S. B. H., Kondo, T. & Ishiguro, H., 2017 Mar 15, In : Journal of Physiology. 595, 6, p. 1947-1972 26 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Bipotential murine hemopoietic cell line (NFS-60) that is responsive to IL-3, GM-CSF, G-CSF, and erythropoietin

Hara, K., Suda, T., Suda, J., Eguchi, M., Ihle, J. N., Nagata, S., Miura, Y. & Saito, M., 1988 Jan 1, In : Experimental Hematology. 16, 4, p. 256-261 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)