The Sakaguchi Laboratory

Research Output 1979 2020

2017
15 Citations (Scopus)

Single fecal microbiota transplantation failed to change intestinal microbiota and had limited effectiveness against ulcerative colitis in Japanese patients

Mizuno, S., Nanki, K., Matsuoka, K., Saigusa, K., Ono, K., Arai, M., Sugimoto, S., Kiyohara, H., Nakashima, M., Takeshita, K., Naganuma, M., Suda, W., Hattori, M. & Kanai, T., 2017, In : Intestinal Research. 15, 1, p. 68-74 7 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Information Services
Tissue Donors
Dysbiosis
Clinical Trials
6 Citations (Scopus)
Mesalamine
colitis
relapse
remission
Ulcerative Colitis
39 Citations (Scopus)

Violet Light Exposure Can Be a Preventive Strategy Against Myopia Progression

Torii, H., Kurihara, T., Seko, Y., Negishi, K., Ohnuma, K., Inaba, T., Kawashima, M., Jiang, X., Kondo, S., Miyauchi, M., Miwa, Y., Katada, Y., Mori, K., Kato, K., Tsubota, K., Goto, H., Oda, M., Hatori, M. & Tsubota, K., 2017 Feb 1, In : EBioMedicine. 15, p. 210-219 10 p.

Research output: Contribution to journalArticle

Contact lenses
Myopia
Elongation
Eyeglasses
Light
159 Citations (Scopus)

Visualization and targeting of LGR5 + human colon cancer stem cells

Shimokawa, M., Ohta, Y., Nishikori, S., Matano, M., Takano, A., Fujii, M., Date, S., Sugimoto, S., Kanai, T. & Sato, T., 2017 May 11, In : Nature. 545, 7653, p. 187-192 6 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Colonic Neoplasms
Neoplasms
Colorectal Neoplasms
Organoids
2016
162 Citations (Scopus)

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

Fujii, M., Shimokawa, M., Date, S., Takano, A., Matano, M., Nanki, K., Ohta, Y., Toshimitsu, K., Nakazato, Y., Kawasaki, K., Uraoka, T., Watanabe, T., Kanai, T. & Sato, T., 2016 Jun 2, In : Cell Stem Cell. 18, 6, p. 827-838 12 p.

Research output: Contribution to journalArticle

Organoids
Colorectal Neoplasms
Carcinogenesis
Transcriptome
Heterografts
47 Citations (Scopus)

Active and water-soluble form of lipidated wnt protein is maintained by a serum glycoprotein afamin/α-albumin

Mihara, E., Hirai, H., Yamamoto, H., Tamura-Kawakami, K., Matano, M., Kikuchi, A., Sato, T. & Takagi, J., 2016 Feb 23, In : eLife. 5, FEBRUARY2016, e11621.

Research output: Contribution to journalArticle

Wnt Proteins
Colony-Forming Units Assay
Detergents
Albumins
Assays
33 Citations (Scopus)

Clinical Efficacy and Safety of Oral Qing-Dai in Patients with Ulcerative Colitis: A Single-Center Open-Label Prospective Study

Sugimoto, S., Naganuma, M., Kiyohara, H., Arai, M., Ono, K., Mori, K., Saigusa, K., Nanki, K., Takeshita, K., Takeshita, T., Mutaguchi, M., Mizuno, S., Bessho, R., Nakazato, Y., Hisamatsu, T., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2016 Mar 10, (Accepted/In press) In : Digestion. p. 193-201 9 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Prospective Studies
Safety
Indigo Carmine
Occult Blood
19 Citations (Scopus)

Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways

Kikuchi, I., Takahashi-Kanemitsu, A., Sakiyama, N., Tang, C., Tang, P. J., Noda, S., Nakao, K., Kassai, H., Sato, T., Aiba, A. & Hatakeyama, M., 2016 Sep 21, In : Nature Communications. 7, 12887.

Research output: Contribution to journalArticle

Hedgehogs
notches
Tyrosine
tyrosine
Phosphorylation

Discrepancy in the classification of water immersion from water exchange colonoscopy

Sugimoto, S. & Mizukami, T., 2016 Mar 1, In : Gastrointestinal Endoscopy. 83, 3, p. 676-677 2 p.

Research output: Contribution to journalLetter

Immersion
Colonoscopy
Pain
Water
13 Citations (Scopus)

EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells

Nakajo, A., Yoshimura, S. I., Togawa, H., Kunii, M., Iwano, T., Izumi, A., Noguchi, Y., Watanabe, A., Goto, A., Sato, T. & Harada, A., 2016, In : Journal of Cell Biology. 212, 3, p. 297-306 10 p.

Research output: Contribution to journalArticle

Carrier Proteins
Epithelial Cells
Small Intestine
Dynamins
Lysosomes
5 Citations (Scopus)

Emergence of undifferentiated colonies from mouse embryonic stem cells undergoing differentiation by retinoic acid treatment

Sharova, L. V., Sharov, A. A., Piao, Y., Stagg, C. A., Amano, T., Qian, Y., Dudekula, D., Schlessinger, D. & Ko, M., 2016 Apr 29, (Accepted/In press) In : In Vitro Cellular and Developmental Biology - Animal. p. 1-9 9 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Tretinoin
Stem cells
Cell Differentiation
Leukemia Inhibitory Factor
1 Citation (Scopus)

Endoscopic Severity Predicts Long-Term Prognosis in Crohn's Disease Patients with Clinical Remission

Naganuma, M., Hisamatsu, T., Matsuoka, K., Kiyohara, H., Arai, M., Sugimoto, S., Mori, K., Nanki, K., Ohno, K., Mutaguchi, M., Mizuno, S., Bessho, R., Nakazato, Y., Hosoe, N., Inoue, N., Iwao, Y., Ogata, H. & Kanai, T., 2016 Jan 1, In : Digestion. 93, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

Crohn Disease
Recurrence
Colonoscopy
C-Reactive Protein
Cohort Studies
1 Citation (Scopus)

Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos

Ishiguro, K. I., Nakatake, Y., Chikazawa-Nohtomi, N., Kimura, H., Akiyama, T., Oda, M., Ko, S. & Ko, M., 2016 Oct 3, (Accepted/In press) In : In Vitro Cellular and Developmental Biology - Animal. p. 1-12 12 p.

Research output: Contribution to journalArticle

Zinc Fingers
Blastocyst
Stem cells
Zinc
Proteins
3 Citations (Scopus)

Gene array analysis of neural crest cells identifies transcription factors necessary for direct conversion of embryonic fibroblasts into neural crest cells

Motohashi, T., Watanabe, N., Nishioka, M., Nakatake, Y., Yulan, P., Mochizuki, H., Kawamura, Y., Ko, M., Goshima, N. & Kunisada, T., 2016 Mar 15, In : Biology Open. 5, 3, p. 311-322 12 p.

Research output: Contribution to journalArticle

neural crest
Neural Crest
Fibroblasts
fibroblasts
Transcription Factors
8 Citations (Scopus)

Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines

Yamamizu, K., Sharov, A. A., Piao, Y., Amano, M., Yu, H., Nishiyama, A., Dudekula, D. B., Schlessinger, D. & Ko, M., 2016 May 6, In : Scientific Reports. 6, 25667.

Research output: Contribution to journalArticle

Gene Expression Profiling
Transcription Factors
Cell Line
Embryonic Stem Cells
Transcriptome
45 Citations (Scopus)

Indole compounds may be promising medicines for ulcerative colitis

Sugimoto, S., Naganuma, M. & Kanai, T., 2016 May 9, (Accepted/In press) In : Journal of Gastroenterology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Indigo Carmine
Tryptophan
Aryl Hydrocarbon Receptors
indole
2 Citations (Scopus)

Induction of specific neuron types by overexpression of single transcription factors

Teratani-Ota, Y., Yamamizu, K., Piao, Y., Sharova, L., Amano, M., Yu, H., Schlessinger, D., Ko, M. & Sharov, A. A., 2016 Jun 1, (Accepted/In press) In : In Vitro Cellular and Developmental Biology - Animal. p. 1-13 13 p.

Research output: Contribution to journalArticle

Neurons
Embryonic Stem Cells
Transcription Factors
Stem cells
GABAergic Neurons
15 Citations (Scopus)

Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response

Saito, Y., Nakaoka, T., Sakai, K., Muramatsu, T., Toshimitsu, K., Kimura, M., Kanai, T., Sato, T. & Saito, H., 2016 May 4, In : Scientific Reports. 6, 25311.

Research output: Contribution to journalArticle

Organoids
DNA Methylation
Neoplasms
DNA
Interferons
9 Citations (Scopus)

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

Dominguez-Brauer, C., Hao, Z., Elia, A. J., Fortin, J. M., Nechanitzky, R., Brauer, P. M., Sheng, Y., Mana, M. D., Chio, I. I. C., Haight, J., Pollett, A., Cairns, R., Tworzyanski, L., Inoue, S., Reardon, C., Marques, A., Silvester, J., Cox, M. A., Wakeham, A., Yilmaz, O. H. & 5 others, Sabatini, D. M., van Es, J. H., Clevers, H., Sato, T. & Mak, T. W., 2016 Aug 4, In : Cell Stem Cell. 19, 2, p. 205-216 12 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Wnt Signaling Pathway
Equidae
Colorectal Neoplasms
Stem Cells
5 Citations (Scopus)

Osteoprotegerin regulates pancreatic β-cell homeostasis upon microbial invasion

Kuroda, Y., Maruyama, K., Fujii, H., Sugawara, I., Ko, S., Yasuda, H., Matsui, H. & Matsuo, K., 2016 Jan 11, In : PLoS One. 11, 1, e0146544.

Research output: Contribution to journalArticle

Osteoprotegerin
lipopolysaccharides
homeostasis
Homeostasis
insulin secretion
15 Citations (Scopus)

Recent trends and future directions for the medical treatment of ulcerative colitis

Naganuma, M., Mizuno, S., Nanki, K., Sugimoto, S. & Kanai, T., 2016 Dec 1, In : Clinical Journal of Gastroenterology. 9, 6, p. 329-336 8 p.

Research output: Contribution to journalReview article

Ulcerative Colitis
Mesalamine
Therapeutics
Tumor Necrosis Factor-alpha
Adrenal Cortex Hormones
35 Citations (Scopus)

SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling

Oudhoff, M. J., Braam, M. J. S., Freeman, S. A., Wong, D., Rattray, D. G., Wang, J., Antignano, F., Snyder, K., Refaeli, I., Hughes, M. R., McNagny, K. M., Gold, M. R., Arrowsmith, C. H., Sato, T., Rossi, F. M. V., Tatlock, J. H., Owen, D. R., Brown, P. J. & Zaph, C., 2016 Apr 4, In : Developmental Cell. 37, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

Catenins
Regeneration
Carcinogenesis
Methylation
Proteins
25 Citations (Scopus)

The ulcerative colitis endoscopic index of severity is useful to predict medium- to long-term prognosis in ulcerative colitis patients with clinical remission

Arai, M., Naganuma, M., Sugimoto, S., Kiyohara, H., Ono, K., Mori, K., Saigusa, K., Nanki, K., Mutaguchi, M., Mizuno, S., Bessho, R., Nakazato, Y., Hosoe, N., Matsuoka, K., Inoue, N., Ogata, H., Iwao, Y. & Kanai, T., 2016, In : Journal of Crohn's and Colitis. 10, 11, p. 1303-1309 7 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Colonoscopy
Recurrence
Hemorrhage
C-Reactive Protein
19 Citations (Scopus)

Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells

Akiyama, T., Wakabayashi, S., Soma, A., Sato, S., Nakatake, Y., Oda, M., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S. & Ko, M., 2016 Oct 15, In : Development (Cambridge). 143, 20, p. 3674-3685 12 p.

Research output: Contribution to journalArticle

Histone Demethylases
Pluripotent Stem Cells
Developmental Genes
Preclinical Drug Evaluations
Cell Transplantation
11 Citations (Scopus)

Ulcerative colitis endoscopic index of severity is associated with long-term prognosis in ulcerative colitis patients treated with infliximab

Saigusa, K., Matsuoka, K., Sugimoto, S., Arai, M., Kiyohara, H., Takeshita, K., Mizuno, S., Mori, K., Nanki, K., Takeshita, T., Nakazato, Y., Yajima, T., Naganuma, M., Hisamatsu, T., Ogata, H., Iwao, Y. & Kanai, T., 2016 Sep 1, In : Digestive Endoscopy. 28, 6, p. 665-670 6 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Therapeutics
Observer Variation
Infliximab
Colonoscopy
29 Citations (Scopus)

Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress

Ohashi, W., Kimura, S., Iwanaga, T., Furusawa, Y., Irié, T., Izumi, H., Watanabe, T., Hijikata, A., Hara, T., Ohara, O., Koseki, H., Sato, T., Robine, S., Mori, H., Hattori, Y., Watarai, H., Mishima, K., Ohno, H., Hase, K. & Fukada, T., 2016 Oct 1, In : PLoS Genetics. 12, 10, e1006349.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
homeostasis
endoplasmic reticulum
transporters
stem cells
4 Citations (Scopus)

Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis

Ishiguro, K. I., Monti, M., Akiyama, T., Kimura, H., Chikazawa-Nohtomi, N., Sakota, M., Sato, S., Redi, C. A., Ko, S. & Ko, M., 2016 Oct 3, (Accepted/In press) In : In Vitro Cellular and Developmental Biology - Animal. p. 1-12 12 p.

Research output: Contribution to journalArticle

Prophase
Oogenesis
Zinc Fingers
Spermatogenesis
Zinc
15 Citations (Scopus)
Zinc Fingers
Transcriptional Activation
Genome
Blastocyst
Heterochromatin
2015
13 Citations (Scopus)

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium

Pin, C., Parker, A., Gunning, A. P., Ohta, Y., Johnson, I. T., Carding, S. R. & Sato, T., 2015 Feb 1, In : Integrative Biology (United Kingdom). 7, 2, p. 213-228 16 p.

Research output: Contribution to journalArticle

Organoids
Intestinal Mucosa
Paneth Cells
Growth
Stem cells
4 Citations (Scopus)

Back to 2D Culture for Ground State of Intestinal Stem Cells

Shimokawa, M. & Sato, T., 2015, In : Cell Stem Cell. 17, 1, p. 5-7 3 p.

Research output: Contribution to journalReview article

Stem Cells
Fetal Stem Cells
Large Intestine
Small Intestine
Population
7 Citations (Scopus)

Combination therapy with infliximab and thiopurine compared to infliximab monotherapy in maintaining remission of postoperative crohn's disease

Sakuraba, A., Okamoto, S., Matsuoka, K., Sato, T., Naganuma, M., Hisamatsu, T., Iwao, Y., Ogata, H., Kanai, T. & Hibi, T., 2015 May 6, In : Digestion. 91, 3, p. 233-238 6 p.

Research output: Contribution to journalArticle

Crohn Disease
Recurrence
Therapeutics
Infliximab
Remission Induction
10 Citations (Scopus)

Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures

Amano, T., Jeffries, E., Amano, M., Ko, A. C., Yu, H. & Ko, M., 2015 May 6, In : DNA Research. 22, 5, p. 331-342 12 p.

Research output: Contribution to journalArticle

Aneuploidy
Down Syndrome
Cell Culture Techniques
Chromosomes, Human, Pair 21
Biological Products
6 Citations (Scopus)

Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes

Sakamoto, H., Takeda, N., Arai, F., Hosokawa, K., Garcia, P., Suda, T., Frampton, J. & Ogawa, M., 2015 Feb 1, In : Stem Cells. 33, 2, p. 479-490 12 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-myb
Hematopoietic Stem Cells
Oncogene Proteins
Hematopoiesis
Bromodeoxyuridine
14 Citations (Scopus)

Diagnostic and therapeutic applications of water-immersion colonoscopy

Sugimoto, S. & Mizukami, T., 2015 Jun 7, In : World Journal of Gastroenterology. 21, 21, p. 6451-6459 9 p.

Research output: Contribution to journalReview article

Open Access
Immersion
Colonoscopy
Colonoscopes
Water
Colon
63 Citations (Scopus)

Efficient genetic engineering of human intestinal organoids using electroporation

Fujii, M., Matano, M., Nanki, K. & Sato, T., 2015 Oct 29, In : Nature Protocols. 10, 10, p. 1474-1485 12 p.

Research output: Contribution to journalArticle

Organoids
Genetic engineering
Genetic Engineering
Electroporation
Genes
21 Citations (Scopus)

ExAtlas: An interactive online tool for meta-analysis of gene expression data

Sharov, A. A., Schlessinger, D. & Ko, M., 2015 Dec 1, In : Journal of Bioinformatics and Computational Biology. 13, 6, 1550019.

Research output: Contribution to journalArticle

Gene expression
Meta-Analysis
Gene Ontology
Genes
Transcriptome
3 Citations (Scopus)

Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese

Kondo, S., Fujiki, K., Ko, S., Yamamoto, A., Nakakuki, M., Ito, Y., Shcheynikov, N., Kitagawa, M., Naruse, S. & Ishiguro, H., 2015 Aug 18, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 4, p. G260-G269

Research output: Contribution to journalArticle

Alcoholic Pancreatitis
Cystic Fibrosis Transmembrane Conductance Regulator
Chronic Pancreatitis
Regulator Genes
Cystic Fibrosis
15 Citations (Scopus)

H1foo Has a Pivotal Role in Qualifying Induced Pluripotent Stem Cells

Kunitomi, A., Yuasa, S., Sugiyama, F., Saito, Y., Seki, T., Kusumoto, D., Kashimura, S., Takei, M., Tohyama, S., Hashimoto, H., Egashira, T., Tanimoto, Y., Mizuno, S., Tanaka, S., Okuno, H., Yamazawa, K., Watanabe, H., Oda, M., Kaneda, R., Matsuzaki, Y. & 5 others, Nagai, T., Okano, H., Yagami, K. I., Tanaka, M. & Fukuda, K., 2015 Apr 28, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Stem cells
Embryonic Stem Cells
Oocytes
Histones
10 Citations (Scopus)

Ink4a/arf-dependent loss of parietal cells induced by oxidative stress promotes CD44-dependent gastric tumorigenesis

Seishima, R., Wada, T., Tsuchihashi, K., Okazaki, S., Yoshikawa, M., Oshima, H., Oshima, M., Sato, T., Hasegawa, H., Kitagawa, Y., Goldenring, J. R., Saya, H. & Nagano, O., 2015 Jun 1, In : Cancer Prevention Research. 8, 6, p. 492-501 10 p.

Research output: Contribution to journalArticle

Stomach
Carcinogenesis
Oxidative Stress
Reactive Oxygen Species
Metaplasia
19 Citations (Scopus)

Maternal TET3 is dispensable for embryonic development but is required for neonatal growth

Tsukada, Y. I., Akiyama, T. & Nakayama, K. I., 2015 Oct 28, In : Scientific reports. 5, 15876.

Research output: Contribution to journalArticle

Open Access
5-Methylcytosine
Zygote
Embryonic Development
Mothers
DNA Methylation
63 Citations (Scopus)

Mini-Gut Organoids: Reconstitution of the Stem Cell Niche

Date, S. & Sato, T., 2015 Nov 13, In : Annual Review of Cell and Developmental Biology. 31, p. 269-289 21 p.

Research output: Contribution to journalArticle

Organoids
Stem Cell Niche
Stem Cells
Carcinogenesis
Epithelium
360 Citations (Scopus)

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids

Matano, M., Date, S., Shimokawa, M., Takano, A., Fujii, M., Ohta, Y., Watanabe, T., Kanai, T. & Sato, T., 2015, In : Nature Medicine. 21, 3, p. 256-262 7 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Organoids
Human Engineering
Tumors
Colorectal Neoplasms
6 Citations (Scopus)

Recognition of and recent issues in hereditary diffuse gastric cancer

Sugimoto, S., Komatsu, H., Morohoshi, Y. & Kanai, T., 2015 Jun 7, In : Journal of Gastroenterology. 50, 8, p. 831-843 13 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Genetic Testing
Mutation
Organoids
Breast Neoplasms
58 Citations (Scopus)

SnapShot: Growing Organoids from Stem Cells

Sato, T. & Clevers, H., 2015 Jun 20, In : Cell. 161, 7, p. 1700-1700.e1

Research output: Contribution to journalComment/debate

Digestive system
Stem cells
Animals
Epithelial Cells
39 Citations (Scopus)

Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer

Oshima, H., Nakayama, M., Han, T. S., Naoi, K., Ju, X., Maeda, Y., Robine, S., Tsuchiya, K., Sato, T., Sato, H., Taketo, M. M. & Oshima, M., 2015 Feb 15, In : Cancer Research. 75, 4, p. 766-776 11 p.

Research output: Contribution to journalArticle

Intestinal Neoplasms
Epithelium
Epithelial Cells
Dextran Sulfate
Intestinal Mucosa
29 Citations (Scopus)

Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells

Akiyama, T., Xin, L., Oda, M., Sharov, A. A., Amano, M., Piao, Y., Cadet, J. S., Dudekula, D. B., Qian, Y., Wang, W., Ko, S. & Ko, M., 2015 May 6, In : DNA Research. 22, 5, p. 307-318 12 p.

Research output: Contribution to journalArticle

Heterochromatin
Genomic Instability
Telomere Homeostasis
Chromatin Assembly and Disassembly
Karyotype
2014
2 Citations (Scopus)

[Homeostatic regulation of hematopoiesis by the hematopoietic stem cell niche]

Takubo, K., 2014 Dec 1, In : Seikagaku. The Journal of Japanese Biochemical Society. 86, 6, p. 755-765 11 p.

Research output: Contribution to journalArticle

Alpha Subunit Hypoxia-Inducible Factor 1
Intracellular Signaling Peptides and Proteins
Endothelial cells
Granulocyte Colony-Stimulating Factor
Cadherins
16 Citations (Scopus)

Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function

Nagamachi, A., Nakata, Y., Ueda, T., Yamasaki, N., Ebihara, Y., Tsuji, K., Honda, Z. I., Takubo, K., Suda, T., Oda, H., Inaba, T. & Honda, H., 2014 Jan 31, In : PLoS One. 9, 1, e87425.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
apoptosis
inflammation
Cells
53 Citations (Scopus)

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 I. Concept and diagnosis of autoimmune pancreatitis

Okazaki, K., Kawa, S., Kamisawa, T., Ito, T., Inui, K., Irie, H., Nishino, T., Notohara, K., Nishimori, I., Tanaka, S., Nishiyama, T., Suda, K., Shiratori, K., Tanaka, M., Shimosegawa, T., Kubo, K., Ohara, H., Irisawa, A., Fujinaga, Y., Hasebe, O. & 19 others, Yamamoto, H., Uchida, K., Kanno, A., Kubota, K., Ko, S., Sakagami, J., Shimizu, K., Sugiyama, M., Tada, M., Nakazawa, T., Nishino, H., Hamano, H., Hirooka, Y., Hirano, K., Masamune, A., Masuda, A., Mizuno, N., Yamaguchi, K. & Yoshida, H., 2014, In : Journal of Gastroenterology. 49, 4, p. 567-588 22 p.

Research output: Contribution to journalArticle

Pancreatitis
Guidelines
Differential Diagnosis
Databases
26 Citations (Scopus)

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 II. Extrapancreatic lesions, differential diagnosis

Kawa, S., Okazaki, K., Kamisawa, T., Kubo, K., Ohara, H., Hasebe, O., Fujinaga, Y., Irisawa, A., Notohara, K., Ito, T., Inui, K., Irie, H., Nishino, T., Nishimori, I., Tanaka, S., Nishiyama, T., Suda, K., Shiratori, K., Tanaka, M., Shimosegawa, T. & 19 others, Yamamoto, H., Uchida, K., Kanno, A., Kubota, K., Ko, S., Sakagami, J., Shimizu, K., Sugiyama, M., Tada, M., Nakazawa, T., Nishino, H., Hamano, H., Hirooka, Y., Hirano, K., Masamune, A., Masuda, A., Mizuno, N., Yamaguchi, K. & Yoshida, H., 2014, In : Journal of Gastroenterology. 49, 5, p. 765-784 20 p.

Research output: Contribution to journalArticle

Pancreatitis
Autoimmune Diseases
Japan
Differential Diagnosis
Guidelines