The Sakaguchi Laboratory

Research Output 1979 2020

2014
113 Citations (Scopus)

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis

Kamisawa, T., Okazaki, K., Kawa, S., Ito, T., Inui, K., Irie, H., Nishino, T., Notohara, K., Nishimori, I., Tanaka, S., Nishiyama, T., Suda, K., Shiratori, K., Tanaka, M., Shimosegawa, T., Kubo, K., Ohara, H., Irisawa, A., Fujinaga, Y., Hasebe, O. & 19 others, Yamamoto, H., Uchida, K., Kanno, A., Kubota, K., Ko, S., Sakagami, J., Shimizu, K., Sugiyama, M., Tada, M., Nakazawa, T., Nishino, H., Hamano, H., Hirooka, Y., Hirano, K., Masamune, A., Masuda, A., Mizuno, N., Yamaguchi, K. & Yoshida, H., 2014, In : Journal of Gastroenterology. 49, 6, p. 961-970 10 p.

Research output: Contribution to journalArticle

Pancreatitis
Guidelines
Steroids
Obstructive Jaundice
Therapeutics
2 Citations (Scopus)

Chromatin properties of regulatory DNA probed by manipulation of transcription factors

Sharov, A. A., Nishiyama, A., Qian, Y., Dudekula, D. B., Longo, D. L., Schlessinger, D. & Ko, M., 2014 Aug 1, In : Journal of Computational Biology. 21, 8, p. 569-577 9 p.

Research output: Contribution to journalArticle

Transcription factors
Chromatin
Transcription Factor
Manipulation
DNA
3 Citations (Scopus)

Classical Th1 cells obtain colitogenicity by co-existence of RORγt-expressing T cells in experimental colitis

Saigusa, K., Hisamatsu, T., Handa, T., Sujino, T., Mikami, Y., Hayashi, A., Mizuno, S., Takeshita, K., Sato, T., Matsuoka, K. & Kanai, T., 2014 Oct 1, In : Inflammatory Bowel Diseases. 20, 10, p. 1820-1827 8 p.

Research output: Contribution to journalArticle

Th1 Cells
Colitis
T-Lymphocytes
Th17 Cells
Cell Count
5 Citations (Scopus)

Continuous low-dose irradiation by I-125 seeds induces apoptosis of gastric cancer cells regardless of histological origin

Takabayashi, K., Kashiwagi, K., Kawata, T., Sato, T., Matsuoka, K., Hisamatsu, T., Takaishi, H., Hibi, T., Ogata, H., Yahagi, N., Kitagawa, Y., Shigematsu, N. & Kanai, T., 2014 Jan, In : Cancer Biology and Therapy. 15, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Seeds
Apoptosis
In Situ Nick-End Labeling
Heterografts
36 Citations (Scopus)

Cross-talk between RORγt + innate lymphoid cells and intestinal macrophages induces mucosal IL-22 production In Crohn's disease

Mizuno, S., Mikami, Y., Kamada, N., Handa, T., Hayashi, A., Sato, T., Matsuoka, K., Matano, M., Ohta, Y., Sugita, A., Koganei, K., Sahara, R., Takazoe, M., Hisamatsu, T. & Kanai, T., 2014, In : Inflammatory Bowel Diseases. 20, 8, p. 1426-1434 9 p.

Research output: Contribution to journalArticle

Crohn Disease
Macrophages
Lymphocytes
interleukin-22
Mucous Membrane
4 Citations (Scopus)

Culturing intestinal stem cells: Applications for colorectal cancer research

Fujii, M. & Sato, T., 2014, In : Frontiers in Genetics. 5, JUN, 169.

Research output: Contribution to journalShort survey

Organoids
Colorectal Neoplasms
Stem Cells
Genetic Models
Human Development

Direct reprogramming of fibroblasts and preadipocytes into functional megakaryocytes.

Matsubara, Y., 2014, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 55, 4, p. 387-395 9 p.

Research output: Contribution to journalArticle

p45 Subunit NF-E2 Transcription Factor
Genetic Transduction
Nuclear Transfer Techniques
Thrombopoietin
Induced Pluripotent Stem Cells
7 Citations (Scopus)

Effectiveness and clinical results of endoscopic management of sigmoid volvulus using unsedated water-immersion colonoscopy

Sugimoto, S., Hosoe, N., Mizukami, T., Tsunoda, Y., Ito, T., Imamura, S., Tamura, T., Nagakubo, S., Morohoshi, Y., Koike, Y., Fujita, Y., Komatsu, H., Ogata, H. & Kanai, T., 2014, In : Digestive Endoscopy. 26, 4, p. 564-568 5 p.

Research output: Contribution to journalArticle

Intestinal Volvulus
Sigmoid Colon
Immersion
Colonoscopy
Water
31 Citations (Scopus)

Efficient generation of integration-free human induced pluripotent stem cells from keratinocytes by simple transfection of episomal vectors

Piao, Y., Hung, S. S. C., Lim, S. Y., Wong, R. C. B. & Ko, M., 2014, In : Stem cells translational medicine. 3, 7, p. 787-791 5 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Keratinocytes
Transfection
Hip
Embryoid Bodies

Endoscopic ultrasound-guided drainage for a mediastinal pancreatic pseudocyst

Sugimoto, S., Yamagishi, Y., Higuchi, H. & Kanai, T., 2014, In : Internal Medicine. 53, 22, p. 2651-2652 2 p.

Research output: Contribution to journalArticle

Interventional Ultrasonography
Alcoholic Pancreatitis
Pancreatic Pseudocyst
Mediastinum
Pleural Effusion
69 Citations (Scopus)

Heterogeneity and hierarchy of hematopoietic stem cells

Ema, H., Morita, Y. & Suda, T., 2014 Feb, In : Experimental Hematology. 42, 2, p. 74-82 9 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Terminology
Cell Differentiation
Stem Cells
Transplantation
9 Citations (Scopus)

Intestinal tumor in a dish

Ohta, Y. & Sato, T., 2014 Jan 1, In : Frontiers in Medicine. 1, MAY, 14.

Research output: Contribution to journalShort survey

Open Access
Colorectal Neoplasms
Organoids
Pharmaceutical Preparations
Neoplasms
Stem Cells
55 Citations (Scopus)

Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling

Kobayashi, I., Kobayashi-Sun, J., Kim, A. D., Pouget, C., Fujita, N., Suda, T. & Traver, D., 2014 Aug 21, In : Nature. 512, 7514, p. 319-323 5 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Somites
Ligands
Blood Vessels
Aorta
32 Citations (Scopus)

KLF5 regulates the integrity and oncogenicity of intestinal stem cells

Nakaya, T., Ogawa, S., Manabe, I., Tanaka, M., Sanada, M., Sato, T., Taketo, M. M., Nakao, K., Clevers, H., Fukayama, M., Kuroda, M. & Nagai, R., 2014 May 15, In : Cancer Research. 74, 10, p. 2882-2891 10 p.

Research output: Contribution to journalArticle

Stem Cells
Catenins
Colorectal Neoplasms
Intestinal Neoplasms
Induced Pluripotent Stem Cells
9 Citations (Scopus)

Macrophages and dendritic cells emerge in the liver during intestinal inflammation and predispose the liver to inflammation

Mikami, Y., Mizuno, S., Nakamoto, N., Hayashi, A., Sujino, T., Sato, T., Kamada, N., Matsuoka, K., Hisamatsu, T., Ebinuma, H., Hibi, T., Yoshimura, A. & Kanai, T., 2014 Jan 2, In : PLoS One. 9, 1, e84619.

Research output: Contribution to journalArticle

Macrophages
dendritic cells
Liver
Dendritic Cells
macrophages
428 Citations (Scopus)

Metabolic requirements for the maintenance of self-renewing stem cells

Ito, K. & Suda, T., 2014, In : Nature Reviews Molecular Cell Biology. 15, 4, p. 243-256 14 p.

Research output: Contribution to journalArticle

Stem Cells
Metabolomics
Glycolysis
Hematopoietic Stem Cells
Metabolic Networks and Pathways
32 Citations (Scopus)

Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress

Tai-Nagara, I., Matsuoka, S., Ariga, H. & Suda, T., 2014 Jan 2, In : Blood. 123, 1, p. 41-50 10 p.

Research output: Contribution to journalArticle

Oxidative stress
Hematopoietic Stem Cells
Stem cells
Oxidative Stress
Reactive Oxygen Species

Not merely quiescent: Telomeres in quiescent HSCs

Nakamura-Ishizu, A. & Suda, T., 2014 Nov 20, In : Blood. 124, 22, p. 3179-3180 2 p.

Research output: Contribution to journalArticle

Animals
Apoptosis
9 Citations (Scopus)

R-spondins/Lgrs expression in tooth development

kawasaki, M., Porntaveetus, T., Kawasaki, K., Oommen, S., Otsuka-Tanaka, Y., Hishinuma, M., Nomoto, T., Maeda, T., Takubo, K., Suda, T., Sharpe, P. T. & Ohazama, A., 2014, In : Developmental Dynamics. 243, 6, p. 844-851 8 p.

Research output: Contribution to journalArticle

Tooth
Diastema
Odontogenesis
Supernumerary Tooth
Tooth Germ
8 Citations (Scopus)

SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)

Yamamizu, K., Schlessinger, D. & Ko, M., 2014 Nov 1, In : Development (Cambridge). 141, 22, p. 4254-4266 13 p.

Research output: Contribution to journalArticle

Germ Layers
Embryonic Stem Cells
Cell Differentiation
Transcription Factors
Doxycycline
10 Citations (Scopus)

Telomerase reverse transcriptase has an extratelomeric function in somatic cell reprogramming

Kinoshita, T., Nagamatsu, G., Saito, S., Takubo, K., Horimoto, K. & Suda, T., 2014 May 30, In : Journal of Biological Chemistry. 289, 22, p. 15776-15787 12 p.

Research output: Contribution to journalArticle

Telomerase
Chromosomes
Stem cells
Induced Pluripotent Stem Cells
Chromosome Aberrations
73 Citations (Scopus)

The analysis, roles and regulation of quiescence in hematopoietic stem cells

Nakamura-Ishizu, A., Takizawa, H. & Suda, T., 2014 Dec 15, In : Development (Cambridge). 141, 24, p. 4656-4666 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Single-Cell Analysis
Multipotent Stem Cells
Intrinsic Factor
Adult Stem Cells
34 Citations (Scopus)

The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells

Kobayashi, C. I., Takubo, K., Kobayashi, H., Nakamura-Ishizu, A., Honda, H., Kataoka, K., Kumano, K., Akiyama, H., Sudo, T., Kurokawa, M. & Suda, T., 2014 Apr 17, In : Blood. 123, 16, p. 2540-2549 10 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Protein-Tyrosine Kinases
Interleukin-2
Stem cells
Leukemia
41 Citations (Scopus)

Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2

Simmini, S., Bialecka, M., Huch, M., Kester, L., Van De Wetering, M., Sato, T., Beck, F., Van Oudenaarden, A., Clevers, H. & Deschamps, J., 2014, In : Nature Communications. 5, 6728.

Research output: Contribution to journalArticle

stem cells
Stem cells
Stomach
Transcription Factors
Stem Cells
2 Citations (Scopus)

Unprecedented cell-selection using ultra-quick freezing combined with aquaporin expression

Kato, Y., Miyauchi, T., Abe, Y., Kojić, D., Tanaka, M., Chikazawa, N., Nakatake, Y., Ko, S., Kobayashi, D., Hazama, A., Fujiwara, S., Uchida, T. & Yasui, M., 2014 Feb 18, In : PLoS One. 9, 2, e87644.

Research output: Contribution to journalArticle

Aquaporins
aquaporins
Freezing
freezing
CHO Cells
2013

[Induction of megakaryocytes and platelet production from mouse and human fibroblasts by p45 NF-E2/Maf].

Ono, Y. & Matsubara, Y., 2013 Nov, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 54, 11, p. 2025-2030 6 p.

Research output: Contribution to journalArticle

p45 Subunit NF-E2 Transcription Factor
Proto-Oncogene Proteins c-maf
Megakaryocytes
Transcription Factors
Blood Platelets

[Intestinal stem cells].

Sato, T., 2013 Sep, In : Seikagaku. The Journal of Japanese Biochemical Society. 85, 9, p. 743-748 6 p.

Research output: Contribution to journalReview article

Stem cells
Cell Division
Intestines
Cell Differentiation
Cultured Cells
22 Citations (Scopus)

A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance

Livigni, A., Peradziryi, H., Sharov, A. A., Chia, G., Hammachi, F., Migueles, R. P., Sukparangsi, W., Pernagallo, S., Bradley, M., Nichols, J., Ko, M. & Brickman, J. M., 2013 Nov 18, In : Current Biology. 23, 22, p. 2233-2244 12 p.

Research output: Contribution to journalArticle

Xenopus
Stem cells
adhesion
stem cells
embryo (animal)
31 Citations (Scopus)

An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity

Shirakawa, T., Yaman-Deveci, R., Tomizawa, S. I., Kamizato, Y., Nakajima, K., Sone, H., Sato, Y., Sharif, J., Yamashita, A., Takada-Horisawa, Y., Yoshida, S., Ura, K., Muto, M., Koseki, H., Suda, T. & Ohbo, K., 2013 Sep 1, In : Development (Cambridge). 140, 17, p. 3565-3576 12 p.

Research output: Contribution to journalArticle

Spermatogonia
Epigenomics
DNA Methylation
Histone Code
Pluripotent Stem Cells
65 Citations (Scopus)

Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy

Lee, J., Kim, K. E., Choi, D. K., Jang, J. Y., Jung, J. J., Kiyonari, H., Shioi, G., Chang, W., Suda, T., Mochizuki, N., Nakaoka, Y., Komuro, I., Yoo, O. J. & Koh, G. Y., 2013 Sep 18, In : Science Translational Medicine. 5, 203, 203ra127.

Research output: Contribution to journalArticle

Angiopoietin-1
Integrins
Blood Vessels
Retinal Vessels
Retinopathy of Prematurity
96 Citations (Scopus)

A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice

Hayashi, A., Sato, T., Kamada, N., Mikami, Y., Matsuoka, K., Hisamatsu, T., Hibi, T., Roers, A., Yagita, H., Ohteki, T., Yoshimura, A. & Kanai, T., 2013 Jun 12, In : Cell Host and Microbe. 13, 6, p. 711-722 12 p.

Research output: Contribution to journalArticle

Clostridium butyricum
Colitis
Interleukin-10
Macrophages
Mucous Membrane
4 Citations (Scopus)

Conversion of primordial germ cells to pluripotent stem cells: Methods for cell tracking and culture conditions

Nagamatsu, G. & Suda, T., 2013, Methods in Molecular Biology. Vol. 1052. p. 49-56 8 p. (Methods in Molecular Biology; vol. 1052).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Tracking
Pluripotent Stem Cells
Germ Cells
Cell Culture Techniques
Fertilization
11 Citations (Scopus)

Cytoplasmic expression of LGR5 in pancreatic adenocarcinoma

Mizuno, N., Yatabe, Y., Hara, K., Hijioka, S., Imaoka, H., Shimizu, Y., Ko, S. & Yamao, K., 2013, In : Frontiers in Physiology. 4 SEP, Article 269.

Research output: Contribution to journalArticle

Adenocarcinoma
Pancreatic Neoplasms
Endocrine Cells
Cytoplasm
Stem Cells

Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice

Handa, T., Kanai, T., Sato, T., Mikami, Y., Sujino, T., Hayashi, A., Mizuno, S., Matsumoto, A., Hisamatsu, T. & Hibi, T., 2013 Feb, In : Immunology Letters. 150, 1-2, p. 123-129 7 p.

Research output: Contribution to journalArticle

Colitis
Dendritic Cells
Bone Marrow
Immune Tolerance
Antigen Presentation
3 Citations (Scopus)

Endoscopic detorsion for sigmoid volvulus using unsedated water-immersion colonoscopy

Sugimoto, S., Mizukami, T., Ito, T., Tsunoda, Y., Imamura, S., Tamura, T., Nagakubo, S., Morohoshi, Y., Koike, Y., Fujita, Y. & Komatsu, H., 2013 Sep 17, In : Endoscopy. 45, SUPPL2

Research output: Contribution to journalComment/debate

Open Access
Intestinal Volvulus
Sigmoid Colon
Immersion
Colonoscopy
Water
13 Citations (Scopus)

Establishment of novel prediction system of intestinal absorption in humans using human intestinal tissues

Miyake, M., Toguchi, H., Nishibayashi, T., Higaki, K., Sugita, A., Koganei, K., Kamada, N., Kitazume, M. T., Hisamatsu, T., Sato, T., Okamoto, S., Kanai, T. & Hibi, T., 2013 Aug, In : Journal of Pharmaceutical Sciences. 102, 8, p. 2564-2571 8 p.

Research output: Contribution to journalArticle

Intestinal Absorption
Pharmaceutical Preparations
Metoprolol
Atenolol
Ulcerative Colitis
486 Citations (Scopus)

Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications

Sato, T. & Clevers, H., 2013, In : Science. 340, 6137, p. 1190-1194 5 p.

Research output: Contribution to journalReview article

Stem Cells
Wnt Receptors
Organoids
Stem Cell Research
Regenerative Medicine
57 Citations (Scopus)

Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7

Nagamachi, A., Matsui, H., Asou, H., Ozaki, Y., Aki, D., Kanai, A., Takubo, K., Suda, T., Nakamura, T., Wolff, L., Honda, H. & Inaba, T., 2013 Sep 9, In : Cancer Cell. 24, 3, p. 305-317 13 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Endosomes
Neoplasms
Cytokine Receptors
Myeloid Leukemia
29 Citations (Scopus)

Hematopoietic stem cell niche: An interplay among a repertoire of multiple functional niches

Nakamura-Ishizu, A. & Suda, T., 2013 Feb, In : Biochimica et Biophysica Acta - General Subjects. 1830, 2, p. 2404-2409 6 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Hematopoietic Stem Cells
Stem cells
Stem Cells
Neoplastic Stem Cells
38 Citations (Scopus)

Identification of transcription factors for lineage-specific ESC differentiation

Yamamizu, K., Piao, Y., Sharov, A. A., Zsiros, V., Yu, H., Nakazawa, K., Schlessinger, D. & Ko, M., 2013 Dec 17, In : Stem Cell Reports. 1, 6, p. 545-559 15 p.

Research output: Contribution to journalArticle

Transcription Factors
Cell Differentiation
Transcriptome
Gene expression
Muscle Cells
20 Citations (Scopus)

IL-22-Producing RORγt-Dependent Innate Lymphoid Cells Play a Novel Protective Role in Murine Acute Hepatitis

Matsumoto, A., Kanai, T., Mikami, Y., Cho, H., Nakamoto, N., Ebinuma, H., Saito, H., Sato, T., Yagita, H. & Hibi, T., 2013 Apr 23, In : PLoS One. 8, 4, e62853.

Research output: Contribution to journalArticle

hepatitis
Liver
Hepatitis
T-cells
Lymphocytes
8 Citations (Scopus)

Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas

Ko, S., Azuma, S., Yokoyama, Y., Yamamoto, A., Kyokane, K., Niida, S., Ishiguro, H. & Ko, M., 2013 Jun 16, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 304, 12

Research output: Contribution to journalArticle

Pancreas
Stem Cells
Inflammation
Pancreatitis
Adrenal Cortex Hormones
602 Citations (Scopus)

In vitro expansion of single Lgr5 + liver stem cells induced by Wnt-driven regeneration

Huch, M., Dorrell, C., Boj, S. F., Van Es, J. H., Li, V. S. W., Van De Wetering, M., Sato, T., Hamer, K., Sasaki, N., Finegold, M. J., Haft, A., Vries, R. G., Grompe, M. & Clevers, H., 2013 Feb 14, In : Nature. 494, 7436, p. 247-250 4 p.

Research output: Contribution to journalArticle

Organoids
Regeneration
Stem Cells
Liver
Bile Ducts
13 Citations (Scopus)

Kinetics of drug selection systems in mouse embryonic stem cells

Nakatake, Y., Fujii, S., Masui, S., Sugimoto, T., Torikai-Nishikawa, S., Adachi, K. & Niwa, H., 2013 Aug 7, In : BMC Biotechnology. 13, 64.

Research output: Contribution to journalArticle

Pharmacokinetics
Transgenes
Genes
Drug Resistance
Pharmaceutical Preparations
31 Citations (Scopus)

Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients

Miyoshi, J., Matsuoka, K., Inoue, N., Hisamatsu, T., Ichikawa, R., Yajima, T., Okamoto, S., Naganuma, M., Sato, T., Kanai, T., Ogata, H., Iwao, Y. & Hibi, T., 2013 Dec 15, In : Journal of Crohn's and Colitis. 7, 12

Research output: Contribution to journalArticle

Tacrolimus
Ulcerative Colitis
Steroids
Remission Induction
Colectomy
4 Citations (Scopus)

Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder.

Sato, T., Ikeda, M., Yotsumoto, S., Shimada, Y., Higuchi, T., Kobayashi, H., Fukuda, T., Ohashi, T., Suda, T. & Ohteki, T., 2013 Apr 18, In : Blood. 121, 16, p. 3267-3273 7 p.

Research output: Contribution to journalArticle

Transplantation Conditioning
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Interferon Type I
Stem cells
Interferons
17 Citations (Scopus)

Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells

Yamashita, M., Nitta, E., Nagamatsu, G., Ikushima, Y. M., Hosokawa, K., Arai, F. & Suda, T., 2013 Nov 8, In : Biochemical and Biophysical Research Communications. 441, 1, p. 196-201 6 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Maintenance
DNA Damage
Apoptosis
111 Citations (Scopus)

Primary mouse small intestinal epithelial cell cultures

Sato, T. & Clevers, H., 2013, Epithelial Cell Culture Protocols: Second Edition. Vol. 945. p. 319-328 10 p. (Methods in Molecular Biology; vol. 945).

Research output: Chapter in Book/Report/Conference proceedingChapter

Stem Cells
Intestinal Mucosa
Cell Culture Techniques
Epithelial Cells
Organoids
24 Citations (Scopus)

Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells.

Ikushima, Y. M., Arai, F., Hosokawa, K., Toyama, H., Takubo, K., Furuyashiki, T., Narumiya, S. & Suda, T., 2013 Mar 14, In : Blood. 121, 11, p. 1995-2007 13 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Prostaglandins E
Stem cells
Mesenchymal Stromal Cells
Receptors, Prostaglandin E, EP2 Subtype
16 Citations (Scopus)

Repression of global protein synthesis by Eif1a-like genes that are expressed specifically in the two-cell embryos and the transient Zscan4-positive state of embryonic stem cells

Hung, S. S. C., Wong, R. C. B., Sharov, A. A., Nakatake, Y., Yu, H. & Ko, M., 2013 Aug, In : DNA Research. 20, 4, p. 391-401 11 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factors
Embryonic Stem Cells
Embryonic Structures
Genes
Proteins