The Sakaguchi Laboratory

Research Output 1979 2020

1990

Analysis of eosinophil-predominant colonies formed by human hemopoietic precursor cells in the presence of purified interleukin-5

Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Mita Hitoshi, S. Y., Tominaga, A. & Takatsu, K., 1990, In : Acta Haematologica Japonica. 53, 4, p. 688-698 11 p.

Research output: Contribution to journalArticle

Interleukin-5
Eosinophils
8 Citations (Scopus)

A new hematopoietic cell line, KMT-2, having human interleukin-3 receptors

Tamura, S., Sugawara, M., Tanaka, H., Tezuka, E., Nihira, S. I., Miyamoto, C., Suda, T. & Ohta, Y., 1990 Aug 1, In : Blood. 76, 3, p. 501-507 7 p.

Research output: Contribution to journalArticle

Interleukin-3 Receptors
Interleukin-3
Cells
Cell Line
Assays
79 Citations (Scopus)

Colony formation of clone-sorted human hematopoietic progenitors

Ema, H., Suda, T., Miura, Y. & Nakauchi, H., 1990 May 15, In : Blood. 75, 10, p. 1941-1946 6 p.

Research output: Contribution to journalArticle

Macrophages
Sorting
Clone Cells
Bone
Blood
5 Citations (Scopus)

Electron microscopic cytochemistry of pseudo-Chediak-Higashi granules in 5 cases of AML

Mizushima, W., Eguchi, M., Sakakibara, H., Sugita, K., Furukawa, T., Kanagawa, M., Suda, T., Yoshida, M., Miura, Y. & Matsui, J., 1990 Jun, In : [Rinsho ketsueki] The Japanese journal of clinical hematology. 31, 6, p. 799-806 8 p.

Research output: Contribution to journalArticle

Histocytochemistry
Diamines
Acid Phosphatase
Peroxidase
Iron
12 Citations (Scopus)

Growth and differentiation of two human megakaryoblastic cell lines; CMK and UT-7.

Miura, Y., Komatsu, N. & Suda, T., 1990, In : Progress in Clinical and Biological Research. 356, p. 259-270 12 p.

Research output: Contribution to journalArticle

Cell Line
Growth
Thrombopoiesis
Phorbol Esters
Granulocyte-Macrophage Colony-Stimulating Factor
360 Citations (Scopus)

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release

Kurihara, N., Bertolini, D., Suda, T., Akiyama, Y. & Roodman, G. D., 1990 Jun 1, In : Journal of Immunology. 144, 11, p. 4226-4230 5 p.

Research output: Contribution to journalArticle

Osteoclasts
Interleukin-1
Interleukin-6
Bone Marrow
Calcitriol
41 Citations (Scopus)

In vitro differentiation of leukemic cells to eosinophils in the presence of interleukin-5 in two cases of acute myeloid leukemia with the translocation (8;21)(q22;q22)

Ema, H., Kitano, K., Suda, T., Sato, Y., Muroi, K., Ohta, M., Yoshida, M., Sakamoto, S., Eguchi, M. & Miura, Y., 1990 Jan 15, In : Blood. 75, 2, p. 350-356 7 p.

Research output: Contribution to journalArticle

Interleukin-5
Eosinophils
Acute Myeloid Leukemia
Cell Differentiation
Bone
38 Citations (Scopus)

In vivo changes of hemopoietic progenitors and the expression of the interleukin 5 gene in eosinophilic mice infected with Toxocara canis

Yamaguchi, Y., Matsui, T., Kasahara, T., Etoh, S., Tominaga, A., Takatsu, K., Miura, Y. & Suda, T., 1990, In : Experimental Hematology. 18, 11, p. 1152-1157 6 p.

Research output: Contribution to journalArticle

Toxocara canis
Interleukin-5
Spleen
Genes
Eosinophils
68 Citations (Scopus)

Role of IL-5 in IL-2-induced eosinophilia: In vivo and in vitro expression of IL-5 mRNA by IL-2 1

Yamaguchi, Y., Suda, T., Shiozaki, H., Miura, Y., Hitoshi, Y., Tominaga, A., Takatsu, K. & Kasahara, T., 1990 Aug 1, In : Journal of Immunology. 145, 3, p. 873-877 5 p.

Research output: Contribution to journalArticle

Interleukin-5
Eosinophilia
Interleukin-1
Interleukin-2
Messenger RNA
136 Citations (Scopus)

Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules

Hayashi, S. I., Kunisada, T., Ogawa, M., Sudo, T., Kodama, H., Suda, T., Nishikawa, S. & Nishikawa, S. I., 1990, In : Journal of Experimental Medicine. 171, 5, p. 1683-1695 13 p.

Research output: Contribution to journalArticle

Inbred BALB C Mouse
Colony-Forming Units Assay
Interleukin-7
Stromal Cells
Hematopoietic Stem Cells
27 Citations (Scopus)

Structural comparison of murine T-cell (B151K12)-derived T-cell-replacing factor (IL-5) with RIL-5: Dimer formation is essential for the expression of biological activity

Takahashi, T., Yamaguchi, N., Mita, S., Yamaguchi, Y., Suda, T., Tominaga, A., Kikuchi, Y., Miura, Y. & Takatsu, K., 1990, In : Molecular Immunology. 27, 9, p. 911-920 10 p.

Research output: Contribution to journalArticle

Interleukin-5
T-Lymphocytes
Amino Acid Sequence
Complementary DNA
Peptides
62 Citations (Scopus)

Target cells for granulocyte colony-stimulating factor, interleukin-3, and interleukin-5 in differentiation pathways of neutrophils and eosinophils

Ema, H., Suda, T., Nagayoshi, K., Miura, Y., Civin, C. I. & Nakauchi, H., 1990 Nov 15, In : Blood. 76, 10, p. 1956-1961 6 p.

Research output: Contribution to journalArticle

Interleukin-3
Interleukin-5
Granulocyte Colony-Stimulating Factor
Eosinophils
Neutrophils
1989
11 Citations (Scopus)

A highly inducible system of gene expression by positive feedback production of glucocorticoid receptors

Ko, M. & Takano, T., 1989, In : DNA. 8, 2, p. 127-133 7 p.

Research output: Contribution to journalArticle

Gene expression regulation
Glucocorticoid Receptors
Gene Expression Regulation
beta-Galactosidase
Viruses
24 Citations (Scopus)

An auto-inducible vector conferring high glucocorticoid inducibility upon stable transformant cells

Ko, M., Naomi, T., Norifumi, S. & Toshiya, T., 1989 Dec 14, In : Gene. 84, 2, p. 383-389 7 p.

Research output: Contribution to journalArticle

Glucocorticoids
Glucocorticoid Receptors
Genes
Reporter Genes
Galactosidases
57 Citations (Scopus)

A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1α

Suda, T., Okada, S., Suda, J., Miura, Y., Ito, M., Sudo, T., Hayashi, S. I., Nishikawa, S. I. & Nakauchi, H., 1989, In : Blood. 74, 6, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

Interleukin-7
Interleukin-1
B-Lymphocytes
Cells
Immunoglobulin M
5 Citations (Scopus)

Cultured human basophils with ultrastructural and ultracytochemical features of mast cells

Eguchi, M., Suda, J., Sugita, K., Suda, T. & Furukawa, T., 1989, In : European Journal of Haematology. 42, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Basophils
Mast Cells
Glycoconjugates
Cytoplasmic Granules
Acid Phosphatase
8 Citations (Scopus)

Effects of the in vivo administration of recombinant human granulocyte colony-stimulating factor following cytotoxic chemotherapy on granulocytic precursors in patients with malignant lymphoma

Ema, H., Suda, T., Sakamoto, S., Tomonaga, T., Tsunoda, J. I., Muroi, K., Komatsu, N., Miwa, A., Ohsaka, A., Yoshida, M., Motoyoshi, K., Takaku, F. & Miura, Y., 1989 Jun, In : Japanese Journal of Cancer Research. 80, 6, p. 577-582 6 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Lymphoma
Bone Marrow
Granulocyte-Macrophage Progenitor Cells
Drug Therapy
207 Citations (Scopus)

Generation of osteoclasts from isolated hematopoietic progenitor cells

Kurihara, N., Suda, T., Miura, Y., Nakauchi, H., Kodama, H., Hiura, K., Hakeda, Y. & Kumegawa, M., 1989, In : Blood. 74, 4, p. 1295-1302 8 p.

Research output: Contribution to journalArticle

Interleukin-3
Osteoclasts
Hematopoietic Stem Cells
Macrophages
Methylcellulose
79 Citations (Scopus)

Growth and differentiation of a human megakaryoblastic cell line, CMK

Komatsu, N., Suda, T., Moroi, M., Tokuyama, N., Sakata, Y., Okada, M., Nishida, T., Hirai, Y., Sato, T., Fuse, A. & Miura, Y., 1989, In : Blood. 74, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Cells
Cell Line
Interleukin-3
Acetates
35 Citations (Scopus)

TREATMENT OF DRUG-INDUCED AGRANULOCYTOSIS WITH GRANULOCYTE-COLONY STIMULATING FACTOR

Muroi, K., Ito, M., Sasaki, R., Suda, T., Sakamoto, S. & Miura, Y., 1989 Jul 1, In : The Lancet. 334, 8653, p. 55 1 p.

Research output: Contribution to journalArticle

Mefenamic Acid
Ketoprofen
Colony-Stimulating Factors
Agranulocytosis
Granulocyte Colony-Stimulating Factor
1988
43 Citations (Scopus)

Bipotential murine hemopoietic cell line (NFS-60) that is responsive to IL-3, GM-CSF, G-CSF, and erythropoietin

Hara, K., Suda, T., Suda, J., Eguchi, M., Ihle, J. N., Nagata, S., Miura, Y. & Saito, M., 1988, In : Experimental Hematology. 16, 4, p. 256-261 6 p.

Research output: Contribution to journalArticle

Interleukin-3
Granulocyte Colony-Stimulating Factor
Granulocyte-Macrophage Colony-Stimulating Factor
Erythropoietin
Cell Line
3 Citations (Scopus)

Confirmation of bone marrow engraftment by detection of M/N blood group antigens on erythroblasts in erythroid bursts

Kitano, K., Kajii, E., Ikemoto, S., Amemiya, Y., Komatsu, N., Suda, T. & Miura, Y., 1988, In : British Journal of Haematology. 69, 3, p. 329-333 5 p.

Research output: Contribution to journalArticle

Erythroblasts
Blood Group Antigens
Erythrocytes
Bone Marrow
Tissue Donors
19 Citations (Scopus)

Difference of cell lineage expression of haematopoietic progenitor cells in Philadelphia-positive acute lymphoblastic leukaemia and chronic myelogenous leukaemia

Kitano, K., Sato, Y., Suda, T. & Miura, Y., 1988, In : British Journal of Haematology. 70, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

Cell Lineage
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hematopoietic Stem Cells
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Karyotype
14 Citations (Scopus)

Differentiation in vitro of T3+ large granular lymphocytes with characteristic cytotoxic activity from an isolated hematopoietic progenitor colony

Minato, N., Hattori, M., Sudo, T., Kano, S., Miura, Y., Suda, J. & Suda, T., 1988, In : Journal of Experimental Medicine. 167, 3, p. 762-776 15 p.

Research output: Contribution to journalArticle

Interleukin-3
Lymphocytes
Hematopoietic Stem Cells
Macrophages
Interleukin-2
38 Citations (Scopus)

Effect of interleukin 6 (IL-6) on the differentiation and proliferation of murine and human hemopoietic progenitors

Suda, T., Yamaguchi, Y., Suda, J., Miura, Y., Okano, A. & Akiyama, Y., 1988, In : Experimental Hematology. 16, 11, p. 891-895 5 p.

Research output: Contribution to journalArticle

Interleukin-6
Neutrophils
Macrophages
Bone Marrow Cells
Granulocyte-Macrophage Progenitor Cells

Effects of IL-5 on eosinophilopoiesis and eosinophil functions

Yamaguchi, Y., Suda, T., Mira, Y. & Takatsu, K., 1988, In : International Journal of Immunopharmacology. 10, SUPPL. 1, p. 52 1 p.

Research output: Contribution to journalArticle

Interleukin-5
Eosinophils
9 Citations (Scopus)

Establishment of megakaryoblastic cell lines by coinfection of Abelson murine leukemia virus and recombinant SV40-retrovirus

Kajigaya, S., Suda, T., Suda, J., Eguchi, M., Moroi, M., Sudo, T., Saito, M. & Miura, Y., 1988 Jun, In : Japanese Journal of Cancer Research. 79, 6, p. 726-733 8 p.

Research output: Contribution to journalArticle

Abelson murine leukemia virus
Retroviridae
Coinfection
Cell Line
Cholinesterases
531 Citations (Scopus)

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor

Yamaguchi, Y., Hayashi, Y., Sugama, Y., Miura, Y., Kasahara, T., Kitamura, S., Torisu, M., Mita, S., Tominaga, A., Takatsu, K. & Suda, T., 1988, In : Journal of Experimental Medicine. 167, 5, p. 1737-1742 6 p.

Research output: Contribution to journalArticle

Eosinophil Chemotactic Factors
Interleukin-5
Eosinophils
Parasitic Diseases
In Vitro Techniques
5 Citations (Scopus)

Karyotype evolution and multilineage involvement of Philadelphia chromosome-positive clones in blastic transformation of two patients with chronic myelocytic leukemia

Sato, Y., Kitano, K., Tsunoda, S., Yoshida, M., Kajii, E., Suda, T., Sakamoto, S., Motoyoshi, K., Saito, M. & Miura, Y., 1988, In : Blood. 71, 6, p. 1561-1567 7 p.

Research output: Contribution to journalArticle

Philadelphia Chromosome
Macrophages
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chromosomes
Stem cells
24 Citations (Scopus)

Platelet peroxidase-positive blast cells in transient myeloproliferative disorder with Down's syndrome

Suda, J., Eguchi, M., Ozawa, T., Furukawa, T., Hayashi, Y., Kojima, S., Maeda, H., Tadokoro, K., Sato, Y., Miura, Y., Ohara, A. & Suda, T., 1988, In : British Journal of Haematology. 68, 2, p. 181-187 7 p.

Research output: Contribution to journalArticle

Peroxidase
Down Syndrome
Blood Platelets
Megakaryocytes
Basophils
5 Citations (Scopus)

Proliferative effect of human granulocyte colony-stimulating factor on blast cells of acute promyelocytic leukemia

Kitano, K., Suda, T., Sato, Y. & Miura, Y., 1988 Jul, In : Japanese Journal of Cancer Research. 79, 7, p. 843-849 7 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Granulocyte Colony-Stimulating Factor
Granulocyte Precursor Cells
Methylcellulose
Metaphase
442 Citations (Scopus)

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors

Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Harada, N., Tominaga, A. & Takatsu, K., 1988, In : Journal of Experimental Medicine. 167, 1, p. 43-56 14 p.

Research output: Contribution to journalArticle

Interleukin-5
Eosinophils
Granulocyte Colony-Stimulating Factor
Interleukin-3
Fluorouracil
1987
55 Citations (Scopus)
Myeloid Leukemia
Calcitriol
Cholecalciferol
Myeloid Cells
Pharmaceutical Preparations
9 Citations (Scopus)

Effect of recombinant human granulocyte colony-stimulating factor on hemopoietic cells in serum-free culture

Ohara, A., Suda, T., Saito, M., Miura, Y., Okabe, T. & Takaku, F., 1987, In : Experimental Hematology. 15, 6, p. 695-699 5 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Erythropoietin
Serum
Neutrophils
Macrophages
23 Citations (Scopus)

Effects of recombinant murine granulocyte colony-stimulating factor on granulocyte-macrophage and blast colony formation

Suda, T., Suda, J., Kajigaya, S., Nagata, S., Asano, S., Saito, M. & Miura, Y., 1987, In : Experimental Hematology. 15, 9, p. 958-965 8 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Granulocytes
Macrophages
Neutrophils
Interleukin-3
2 Citations (Scopus)

Erythroid- and myeloid-lineage involvement in chronic myelomonocytic leukemia

Sato, Y., Suda, T., Suda, J., Saito, M. & Miura, Y., 1987, In : Experimental Hematology. 15, 4, p. 316-322 7 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Metaphase
Clone Cells
Chromosomes
Erythroblasts
2 Citations (Scopus)

Nude mice bearing human CSF-producing tumor: Analysis of hemopoietic factor(s) acting on primitive stem cells

Takeda, K., Suda, T., Sudo, T. & Miura, Y., 1987, In : Cell Structure and Function. 12, 3, p. 273-280 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Survival of highly proliferative colony forming cells after treatment bone marrow cells with 4-hydroperoxycyclophosphamide

Komatsu, N., Suda, T., Suda, J. & Miura, Y., 1987, In : Cancer Research. 47, 23, p. 6371-6376 6 p.

Research output: Contribution to journalArticle

perfosfamide
Bone Marrow Cells
Survival
Myeloid Progenitor Cells
Erythroid Precursor Cells

The role of interleukin-3 in the proliferation of murine mast cells in vitro

Mori, M., Suda, T., Suda, J., Miura, Y. & Saito, M., 1987, In : Acta Haematologica Japonica. 50, 1, p. 59-64 6 p.

Research output: Contribution to journalArticle

Interleukin-3
Mast Cells
Pokeweed Mitogens
Spleen
Conditioned Culture Medium
1986
10 Citations (Scopus)

A recombinant murine granulocyte/macrophage (GM) colony-stimulating factor derived from an inducer T cell line (IH5.5). Functional restriction to GM progenitor cells

Kajigaya, S., Suda, T., Suda, J., Saito, M., Miura, Y., Iizuka, M., Kobayashi, S., Minato, N. & Sudo, T., 1986, In : Journal of Experimental Medicine. 164, 4, p. 1102-1113 12 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Progenitor Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Helper-Inducer T-Lymphocytes
Macrophages
T-Lymphocytes

Erythropoietic activity in mouse spleen cell-conditioned medium detected by erythroid colony formation of fetal mouse liver cells in serum-free cultures

Kajigaya, S., Kubota, K., Suda, T. & Miura, Y., 1986, In : Acta Haematologica Japonica. 49, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Conditioned Culture Medium
Spleen
Erythropoietin
Liver
Erythroid Precursor Cells
37 Citations (Scopus)

Megakaryocytopoiesis in vitro of patients with essential thrombocythaemia: Effect of plasma and serum on megakaryocytic colony formation

Komatsu, N., Suda, T., Sakata, Y., Eguchi, M., Kaji, K., Saito, M. & Miura, Y., 1986, In : British Journal of Haematology. 64, 2, p. 241-252 12 p.

Research output: Contribution to journalArticle

Thrombopoiesis
Essential Thrombocythemia
Megakaryocytes
Phytohemagglutinins
Serum
26 Citations (Scopus)

Multilineage expression of haemopoietic precursors with an abnormal clone in idiopathic myelofibrosis

Sato, Y., Suda, T., Suda, J., Ohsaka, A., Kubota, K., Saito, M. & Miura, Y., 1986, In : British Journal of Haematology. 64, 4, p. 657-667 11 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Metaphase
Clone Cells
Cell Line
Blood Cells
6 Citations (Scopus)

Myeloid and erythroid lineage expression of haemopoietic progenitors derived from an abnormal clone in erythroleukaemia

Suda, T., Sato, Y., Furukawa, Y., Eguchi, M., Saito, M. & Miura, Y., 1986, In : British Journal of Haematology. 64, 4, p. 647-656 10 p.

Research output: Contribution to journalArticle

Leukemia, Erythroblastic, Acute
Metaphase
Clone Cells
Bone Marrow Cells
Chromosomes
27 Citations (Scopus)

Purified interleukin-3 and erythropoietin support the terminal differentiation of hemopoietic progenitors in serum-free culture

Suda, J., Suda, T., Kubota, K., Ihle, J. N., Saito, M. & Miura, Y., 1986, In : Blood. 67, 4, p. 1002-1006 5 p.

Research output: Contribution to journalArticle

Interleukin-3
Erythropoietin
Erythroid Cells
Serum
Stem Cells
1985
36 Citations (Scopus)

Clonal analysis of basophil differentiation in bone marrow cultures from a Down's syndrome patient with megakaryoblastic leukemia

Suda, T., Suda, J., Miura, Y., Hayashi, Y., Eguchi, M., Tadokoro, K. & Saito, M., 1985, In : Blood. 66, 6, p. 1278-1283 6 p.

Research output: Contribution to journalArticle

Methylcellulose
Basophils
Down Syndrome
Histamine
Bone

Proliferation and differentiation of murine mast cells in vitro

Suda, T., 1985, In : Acta Haematologica Japonica. 48, 8, p. 1937-1945 9 p.

Research output: Contribution to journalArticle

Mast Cells
Cell Proliferation
Colony-Stimulating Factors
In Vitro Techniques
Cell Differentiation
337 Citations (Scopus)

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

Noda, M., Ko, M., Ogura, A., Liu, D. G., Amano, T., Takano, T. & Ikawa, Y., 1985, In : Nature. 318, 6041, p. 73-75 3 p.

Research output: Contribution to journalArticle

ras Genes
PC12 Cells
Sarcoma
Nerve Growth Factor
Viruses
1983

An autopsy case of Reye syndrome during a remission of malignant lymphoma

Hamano, Y., Suda, T., Kamoshita, S. & Koike, M., 1983, In : No To Hattatsu. 15, 5, p. 438-444 7 p.

Research output: Contribution to journalArticle

Reye Syndrome
Autopsy
Lymphoma
Encephalocele
Tachypnea

Birbeck like granules in 3 cases of acute leukemia of children

Yamamoto, S., Eguchi, M., Kato, K., Sugiyama, S., Furukawa, T., Sekine, I. & Suda, T., 1983, In : Acta Haematologica Japonica. 46, 6, p. 1216-1221 6 p.

Research output: Contribution to journalArticle