The Sakaguchi Laboratory

Research Output

1992

Function, molecular structure and gene expression of stem cell factor (SCF)

Okada, S. & Suda, T., 1992 Aug, In : Nippon rinsho. Japanese journal of clinical medicine. 50, 8, p. 1872-1878 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Granulocyte-macrophage colony-stimulating factor and erythropoietin act competitively to induce two different programs of differentiation in the human pluripotent cell line UT-7

Hermine, O., Mayeux, P., Titeux, M., Mitjavila, M. T., Casadevall, N., Guichard, J., Komatsu, N., Suda, T., Miura, Y., Vainchenker, W. & Breton-Gorius, J., 1992 Jan 1, In : Blood. 80, 12, p. 3060-3069 10 p.

Research output: Contribution to journalArticle

Open Access
53 Citations (Scopus)

Herbimycin A, an Inhibitor of Tyrosine Kinase, Prolongs Survival of Mice Inoculated with Myeloid Leukemia CI Cells with High Expression of v-abl Tyrosine Kinase

Honma, Y., Okabe-Kado, J., Kasukabe, T., Hozumi, M., Kodama, H., Kajigaya, S., Suda, T. & Miura, Y., 1992 Jul, In : Cancer Research. 52, 14, p. 4017-4020 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

In vitro reconstitution of an erythropoietin gene transcription system using its 5′-flanking sequence and a nuclear extract from anemic kidney

Tsuchiya, T., Ochiai, H., Imajoh-Ohmi, S., Ueda, M., Suda, T., Nakamura, M. & Kanegasaki, S., 1992 Jan 15, In : Biochemical and Biophysical Research Communications. 182, 1, p. 137-143 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells

Okada, S., Nakauchi, H., Nagayoshi, K., Nishikawa, S. I., Miura, Y. & Suda, T., 1992 Dec 1, In : Blood. 80, 12, p. 3044-3050 7 p.

Research output: Contribution to journalArticle

394 Citations (Scopus)

Megaloblastic Anemia Associated with Psoriasis: Case Report and Review of the Literature

Iwama, A., Miwa, A., Suzuki, T., Ema, H., Suda, T., Sakamoto, S. & Miura, Y., 1992 Jan 1, In : Internal Medicine. 31, 1, p. 127-130 4 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens: Absence of reactivity with normal hematopoietic progenitor cells

Muroi, K., Suda, T., Nojiri, H., Ema, H., Amemiya, Y., Miura, Y., Nakauchi, H., Singhal, A. & Hakomori, S. I., 1992 Jan 1, In : Blood. 79, 3, p. 713-719 7 p.

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

Suppressive Effect of LD78 on the Proliferation of Human Hemopoietic Progenitors

Shiozaki, H., Ide, T., Nakao, J., Imamura, T., Nakamura, M., Shimada, K., Miura, Y. & Suda, T., 1992 May, In : Japanese Journal of Cancer Research. 83, 5, p. 499-504 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synergistic effect of IL-3 and IL-6 on highly enriched murine hemopoietic progenitors

Okada, S., Nakauchi, H., Nagayoshi, K., Nakamura, M., Miura, Y. & Suda, T., 1992 Jan 1, In : Experimental Hematology. 20, 5, p. 546-551 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Two Cases of Acute Myeloid Leukemia Evolving into a Chronic Myelomonocytic Leukemia-like State after Induction Therapy

Iwama, A., Miwa, A., Suzuki, T., Komatsu, N., Yoshida, M., Suda, T., Sakamoto, S. & Miura, Y., 1992 Jan 1, In : Internal Medicine. 31, 2, p. 214-217 4 p.

Research output: Contribution to journalArticle

Open Access

Two types of murine CD34 mRNA generated by alternative splicing

Suda, J., Sudo, T., Ito, M., Ohno, N., Yamaguchi, Y. & Suda, T., 1992, In : Blood. 79, 9, p. 2288-2295 8 p.

Research output: Contribution to journalArticle

Open Access
57 Citations (Scopus)
1991

Analysis of the survival of mature human eosinophils: Interleukin-5 prevents apoptosis in mature human eosinophils

Yamaguchi, Y., Suda, T., Ohta, S., Tominaga, K., Miura, Y. & Kasahara, T., 1991 Jan 1, In : Blood. 78, 10, p. 2542-2547 6 p.

Research output: Contribution to journalArticle

Open Access
255 Citations (Scopus)

Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor

Kodama, H., Yamasaki, A., Nose, M., Niida, S., Ohgame, Y., Abe, M., Kumegawa, M. & Suda, T., 1991 Jan 1, In : Journal of Experimental Medicine. 173, 1, p. 269-272 4 p.

Research output: Contribution to journalArticle

Open Access
320 Citations (Scopus)

Cytokines and diseases: hematopoietic factors and hematological diseases

Suda, T., 1991 Sep 10, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 80, 9, p. 1383-1387 5 p.

Research output: Contribution to journalReview article

Open Access

Effect of synthesized constituents in the L-tryptophan product on the differentiation of eosinophils and the induction of IL-6: A possible cause of eosinophilia-myalgia syndrome

Yamaguchi, Y., Tsunoda, J. I., Suda, T., Miura, Y., Shioiri-Nakano, K. & Kasahara, T., 1991 Aug 15, In : Biochemical and Biophysical Research Communications. 178, 3, p. 1008-1013 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Effects of interleukin 3, interleukin 6, and granulocyte colony-stimulating factor on sorted murine splenic progenitor cells

Okada, S., Suda, T., Suda, J., Tokuyama, N., Nagayoshi, K., Miura, Y. & Nakauchi, H., 1991 Mar 8, In : Experimental Hematology. 19, 1, p. 42-46 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
261 Citations (Scopus)

Function of hemopoietic stem cells

Suda, T., 1991 May, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 36, 7, p. 1202-1210 9 p.

Research output: Contribution to journalArticle

Generation of b lymphocytes from a single hemopoietic progenitor cell in vitro

Ohara, A., Suda, T., Tokuyama, N., Suda, J., Nakayama, K. I., Miura, Y., Nishikawa, S. I. & Nakauchi, H., 1991 Jul, In : International immunology. 3, 7, p. 703-709 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Hematopoietic Factors and Hematological Diseases

Suda, T., 1991 Jan 1, In : Japanese Journal of Medicine. 30, 6, p. 600-602 3 p.

Research output: Contribution to journalArticle

Open Access

Induction by some protein kinase inhibitors of differentiation of a mouse megakaryoblastic cell line established by coinfection with Abelson murine leukemia virus and recombinant SV40 retrovirus

Honma, Y., Okabe-Kado, J., Kasukabe, T., Hozumi, M., Kajigaya, S., Suda, T. & Miura, Y., 1991 Sep 1, In : Cancer Research. 51, 17, p. 4649-4655 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Long-term bone marrow failure accompanied by skin pigmentation

Muroi, K., Amemiya, Y., Miwa, A., Suda, T., Sakamoto, S., Noguchi, K. & Miura, Y., 1991 Jan 1, In : International journal of hematology. 54, 4, p. 281-287 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Multiple myeloma with hemolytic anemia and thrombocytopenia

Muroi, K., Imagawa, S., Suda, T., Kajii, E., Otuka, Y., Sakurabayashi, I., Amemiya, Y., Sakamoto, S. & Miura, Y., 1991 Aug, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 32, 8, p. 909-911 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Multipotent and Committed CD34+ Cells in Bone Marrow Transplantation

Ema, H., Suda, T., Nakauchi, H., Nakamura, Y., Iwama, A., Imagawa, S., Akutsu, M., Kano, Y., Kato, S., Yabe, M., Yoshida, M., Sakamoto, S., Amemiya, Y. & Miura, Y., 1991 May, In : Japanese Journal of Cancer Research. 82, 5, p. 547-552 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Response of newly established mouse myeloid leukemic cell lines to MC3T3-G2/PA6 preadipocytes and hematopoietic factors

Kodama, H., Iizuka, M., Tomiyama, T., Yoshida, K., Seki, M., Suda, T. & Nishikawa, S. I., 1991, In : Blood. 77, 1, p. 49-54 6 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Support of early B-cell differentiation in mouse fetal liver by stromal cells and interleukin-7

Gunji, Y., Suda, J., Yamaguchi, Y., Nakauchi, H., Nishikawa, S. I., Yanai, N., Obinata, M., Yanagisawa, M., Miura, Y. & Suda, T., 1991, In : Blood. 77, 12, p. 2612-2617 6 p.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)
1990

Analysis of eosinophil-predominant colonies formed by human hemopoietic precursor cells in the presence of purified interleukin-5

Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Mita Hitoshi, S. Y., Tominaga, A. & Takatsu, K., 1990 Jan 1, In : Acta Haematologica Japonica. 53, 4, p. 688-698 11 p.

Research output: Contribution to journalArticle

A new hematopoietic cell line, KMT-2, having human interleukin-3 receptors

Tamura, S., Sugawara, M., Tanaka, H., Tezuka, E., Nihira, S., Miyamoto, C., Suda, T. & Ohta, Y., 1990, In : Blood. 76, 3, p. 501-507 7 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Colony formation of clone-sorted human hematopoietic progenitors

Ema, H., Suda, T., Miura, Y. & Nakauchi, H., 1990 Jan 1, In : Blood. 75, 10, p. 1941-1946 6 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Electron microscopic cytochemistry of pseudo-Chediak-Higashi granules in 5 cases of AML

Mizushima, W., Eguchi, M., Sakakibara, H., Sugita, K., Furukawa, T., Kanagawa, M., Suda, T., Yoshida, M., Miura, Y. & Matsui, J., 1990 Jun 1, In : [Rinsho ketsueki] The Japanese journal of clinical hematology. 31, 6, p. 799-806 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Growth and differentiation of two human megakaryoblastic cell lines; CMK and UT-7.

Miura, Y., Komatsu, N. & Suda, T., 1990, In : Progress in clinical and biological research. 356, p. 259-270 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release

Kurihara, N., Bertolini, D., Suda, T., Akiyama, Y. & Roodman, G. D., 1990 Jan 1, In : Journal of Immunology. 144, 11, p. 4226-4230 5 p.

Research output: Contribution to journalArticle

365 Citations (Scopus)

In vitro differentiation of leukemic cells to eosinophils in the presence of interleukin-5 in two cases of acute myeloid leukemia with the translocation (8;21) (q22;q22)

Ema, H., Kitano, K., Suda, T., Sato, Y., Muroi, K., Ohta, M., Yoshida, M., Sakamoto, S., Eguchi, M. & Miura, Y., 1990, In : Blood. 75, 2, p. 350-356 7 p.

Research output: Contribution to journalArticle

Open Access
41 Citations (Scopus)

In vivo changes of hemopoietic progenitors and the expression of the interleukin 5 gene in eosinophilic mice infected with Toxocara canis

Yamaguchi, Y., Matsui, T., Kasahara, T., Etoh, S., Tominaga, A., Takatsu, K., Miura, Y. & Suda, T., 1990 Dec 1, In : Experimental Hematology. 18, 11, p. 1152-1157 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Role of IL-5 in IL-2-induced eosinophilia. In vivo and in vitro expression of IL-5 mRNA by IL-2

Yamaguchi, Y., Suda, T., Shiozaki, H., Miura, Y., Hitoshi, Y., Tominaga, A., Takatsu, K. & Kasahara, T., 1990 Jan 1, In : Journal of Immunology. 145, 3, p. 873-877 5 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Structural comparison of murine T-cell (B151K12)-derived T-cell-replacing factor (IL-5) with RIL-5: Dimer formation is essential for the expression of biological activity

Takahashi, T., Yamaguchi, N., Mita, S., Yamaguchi, Y., Suda, T., Tominaga, A., Kikuchi, Y., Miura, Y. & Takatsu, K., 1990 Sep, In : Molecular Immunology. 27, 9, p. 911-920 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Target cells for granulocyte colony-stimulating factor, interleukin-3, and interleukin-5 in differentiation pathways of neutrophils and eosinophils

Ema, H., Suda, T., Nagayoshi, K., Miura, Y., Civin, C. I. & Nakauchi, H., 1990 Jan 1, In : Blood. 76, 10, p. 1956-1961 6 p.

Research output: Contribution to journalArticle

Open Access
66 Citations (Scopus)
1989

A Highly Inducible System of Gene Expression by Positive Feedback Production of Glucocorticoid Receptors

Ko, M. S. H. & Takano, T., 1989 Mar, In : DNA. 8, 2, p. 127-133 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

An auto-inducible vector conferring high glucocorticoid inducibility upon stable transformant cells

Ko, M. S. H., Naomi, T., Norifumi, S. & Toshiya, T., 1989 Dec 14, In : Gene. 84, 2, p. 383-389 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1α

Suda, T., Okada, S., Suda, J., Miura, Y., Ito, M., Sudo, T., Hayashi, S. I., Nishikawa, S. I. & Nakauchi, H., 1989, In : Blood. 74, 6, p. 1936-1941 6 p.

Research output: Contribution to journalArticle

Open Access
60 Citations (Scopus)

Cultured human basophils with ultrastructural and ultracytochemical features of mast cells

Eguchi, M., Suda, J., Sugita, K., Suda, T. & Furukawa, T., 1989 Jan, In : European Journal of Haematology. 42, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effects of the in vivo Administration of Recombinant Human Granulocyte Colony‐stimulating Factor Following Cytotoxic Chemotherapy on Granulocytic Precursors in Patients with Malignant Lymphoma

Ema, H., Suda, T., Sakamoto, S., Tomonaga, T., Tsunoda, J. ., Muroi, K., Komatsu, N., Miwa, A., Ohsaka, A., Yoshida, M., Motoyoshi, K., Takaku, F. & Miura, Y., 1989 Jun, In : Japanese Journal of Cancer Research. 80, 6, p. 577-582 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Generation of osteoclasts from isolated hematopoietic progenitor cells

Kurihara, N., Suda, T., Miura, Y., Nakauchi, H., Kodama, H., Hiura, K., Hakeda, Y. & Kumegawa, M., 1989, In : Blood. 74, 4, p. 1295-1302 8 p.

Research output: Contribution to journalArticle

Open Access
208 Citations (Scopus)

Growth and differentiation of a human megakaryoblastic cell line, CMK

Komatsu, N., Suda, T., Moroi, M., Tokuyama, N., Sakata, Y., Okada, M., Nishida, T., Hirai, Y., Sato, T., Fuse, A. & Miura, Y., 1989 Jan 1, In : Blood. 74, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

TREATMENT OF DRUG-INDUCED AGRANULOCYTOSIS WITH GRANULOCYTE-COLONY STIMULATING FACTOR

Muroi, K., Ito, M., Sasaki, R., Suda, T., Sakamoto, S. & Miura, Y., 1989 Jul 1, In : The Lancet. 334, 8653, 1 p.

Research output: Contribution to journalLetter

35 Citations (Scopus)
1988

Bipotential murine hemopoietic cell line (NFS-60) that is responsive to IL-3, GM-CSF, G-CSF, and erythropoietin

Hara, K., Suda, T., Suda, J., Eguchi, M., Ihle, J. N., Nagata, S., Miura, Y. & Saito, M., 1988 Jan 1, In : Experimental Hematology. 16, 4, p. 256-261 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Confirmation of bone marrow engraftment by detection of M/N blood group antigens on erythroblasts in erythroid bursts

Kitano, K., Kajii, E., Ikemoto, S., Amemiya, Y., Komatsu, N., Suda, T. & Miura, Y., 1988 Jan 1, In : British Journal of Haematology. 69, 3, p. 329-333 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Difference of cell lineage expression of haematopoietic progenitor cells in Philadelphia-positive acute lymphoblastic leukaemia and chronic myelogenous leukaemia

Kitano, K., Sato, Y., Suda, T. & Miura, Y., 1988 Jan 1, In : British Journal of Haematology. 70, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Effect of interleukin 6 (IL-6) on the differentiation and proliferation of murine and human hemopoietic progenitors

Suda, T., Yamaguchi, Y., Suda, J., Miura, Y., Okano, A. & Akiyama, Y., 1988 Dec 1, In : Experimental Hematology. 16, 11, p. 891-895 5 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Effects of IL-5 on eosinophilopoiesis and eosinophil functions

Yamaguchi, Y., Suda, T., Mira, Y. & Takatsu, K., 1988, In : International Journal of Immunopharmacology. 10, SUPPL. 1, 1 p.

Research output: Contribution to journalArticle