The Sakaguchi Laboratory

Research Output 1979 2019

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Review article
2019
2 Citations (Scopus)

Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine

Akiyama, S., Matsuoka, K., Fukuda, K., Hamada, S., Shimizu, M., Nanki, K., Mizuno, S., Kiyohara, H., Arai, M., Sugimoto, S., Iwao, Y., Ogata, H., Hisamatsu, T., Naganuma, M., Motobayashi, M., Suzuki, K., Takenaka, K., Fujii, T., Saito, E., Nagahori, M. & 5 others, Ohtsuka, K., Mochizuki, M., Watanabe, M., Hashiguchi, M. & Kanai, T., 2019 Jan 1, In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalReview article

Inflammatory Bowel Diseases
Erythrocyte Indices
Leukopenia
Leukocyte Count
Genotype
6 Citations (Scopus)

Modeling Human Digestive Diseases With CRISPR-Cas9–Modified Organoids

Fujii, M., Clevers, H. & Sato, T., 2019 Feb 1, In : Gastroenterology. 156, 3, p. 562-576 15 p.

Research output: Contribution to journalReview article

Clustered Regularly Interspaced Short Palindromic Repeats
Organoids
Technology
Digestive System Diseases
Stem Cell Niche
2018
24 Citations (Scopus)

Advancing Intestinal Organoid Technology Toward Regenerative Medicine

Nakamura, T. & Sato, T., 2018 Jan 1, In : CMGH. 5, 1, p. 51-60 10 p.

Research output: Contribution to journalReview article

Organoids
Regenerative Medicine
Technology
Intestines
Tissue Scaffolds
5 Citations (Scopus)

Gastroenteropancreatic neuroendocrine neoplasms: genes, therapies and models

Kawasaki, K., Fujii, M. & Sato, T., 2018 Feb 26, In : Disease models & mechanisms. 11, 2

Research output: Contribution to journalReview article

Gene therapy
Neoplasm Genes
Genetic Therapy
Neoplasms
Organoids
2017
1 Citation (Scopus)

Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem Cells

Akiyama, T., Wakabayashi, S., Soma, A., Sato, S., Nakatake, Y., Oda, M., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S. & Ko, M., 2017, In : Stem Cells International. 2017, 7215010.

Research output: Contribution to journalReview article

Pluripotent Stem Cells
Epigenomics
Muscle Cells
Skeletal Muscle
Transcription Factors
2016
13 Citations (Scopus)

Recent trends and future directions for the medical treatment of ulcerative colitis

Naganuma, M., Mizuno, S., Nanki, K., Sugimoto, S. & Kanai, T., 2016 Dec 1, In : Clinical Journal of Gastroenterology. 9, 6, p. 329-336 8 p.

Research output: Contribution to journalReview article

Ulcerative Colitis
Mesalamine
Therapeutics
Tumor Necrosis Factor-alpha
Adrenal Cortex Hormones
2015
4 Citations (Scopus)

Back to 2D Culture for Ground State of Intestinal Stem Cells

Shimokawa, M. & Sato, T., 2015, In : Cell Stem Cell. 17, 1, p. 5-7 3 p.

Research output: Contribution to journalReview article

Stem Cells
Fetal Stem Cells
Large Intestine
Small Intestine
Population
14 Citations (Scopus)

Diagnostic and therapeutic applications of water-immersion colonoscopy

Sugimoto, S. & Mizukami, T., 2015 Jun 7, In : World Journal of Gastroenterology. 21, 21, p. 6451-6459 9 p.

Research output: Contribution to journalReview article

Open Access
Immersion
Colonoscopy
Colonoscopes
Water
Colon
2013

[Intestinal stem cells].

Sato, T., 2013 Sep, In : Seikagaku. The Journal of Japanese Biochemical Society. 85, 9, p. 743-748 6 p.

Research output: Contribution to journalReview article

Stem cells
Cell Division
Intestines
Cell Differentiation
Cultured Cells
474 Citations (Scopus)

Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications

Sato, T. & Clevers, H., 2013, In : Science. 340, 6137, p. 1190-1194 5 p.

Research output: Contribution to journalReview article

Stem Cells
Wnt Receptors
Organoids
Stem Cell Research
Regenerative Medicine