The Sakaguchi Laboratory of Developmental Biology Department of Systems Medicine

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Stem cells Chemical Compounds
Embryonic Stem Cells Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Pluripotent Stem Cells Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Genes Medicine & Life Sciences
Blastocyst Medicine & Life Sciences
Cell Differentiation Medicine & Life Sciences

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Research Output 1985 2018

1 Citations

Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing

Akiyama, T., Sato, S., Chikazawa-Nohtomi, N., Soma, A., Kimura, H., Wakabayashi, S., Ko, S. B. H. & Ko, M. S. H., 2018 Dec 1, In : Scientific Reports. 8, 1, 1189.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Muscle Cells
Skeletal Muscle
RNA
Gene Knockdown Techniques

Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors 10 Technology 1004 Medical Biotechnology

Ida, H., Akiyama, T., Ishiguro, K., Goparaju, S. K., Nakatake, Y., Chikazawa-Nohtomi, N., Sato, S., Kimura, H., Yokoyama, Y., Nagino, M., Ko, M. & Ko, S., 2018 Oct 25, In : Stem Cell Research and Therapy. 9, 1, 277.

Research output: Contribution to journalArticle

Endocrine Cells
Biotechnology
Stem cells
Transcription Factors
Cells

Selective modulation of local linkages between active transcription and oxidative demethylation activity shapes cardiomyocyte-specific gene-body epigenetic status in mice

Oda, M., Wakabayashi, S., Ari Wijetunga, N., Yuasa, S., Enomoto, H., Kaneda, R., Yoon, S. H., Mittal, N., Jing, Q., Suzuki, M., Greally, J. M., Fukuda, K. & Makino, S., 2018 May 10, In : BMC Genomics. 19, 1, 349.

Research output: Contribution to journalArticle

Cardiac Myocytes
Epigenomics
Genes
Body Regions
Histone Code