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Research Output 1986 2019

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1986
7 Citations (Scopus)

In vitro production of autoantibodies to U1 ribonucleoproteins by peripheral blood mononuclear cells from patients with connective tissue diseases

Ohosone, Y., Akizuki, M., Hirakata, M., Satoh, M., Yamagata, H. & Homma, M., 1986, In : Arthritis and Rheumatism. 29, 11, p. 1343-1350 8 p.

Research output: Contribution to journalArticle

Ribonucleoproteins
Connective Tissue Diseases
Autoantibodies
Blood Cells
Antibodies
1988
15 Citations (Scopus)

Coexistence of CREST syndrome and primary biliary cirrhosis. Serological studies of two cases

Hirakata, M., Akizuki, M., Miyachi, K., Matsushima, H., Okano, T. & Homma, M., 1988, In : Journal of Rheumatology. 15, 7, p. 1166-1170 5 p.

Research output: Contribution to journalArticle

CREST Syndrome
Biliary Liver Cirrhosis
Antibody Specificity
Antibodies
Centromere
5 Citations (Scopus)

Pyloric stenosis in a patient with progressive systemic sclerosis

Hirakata, M., Akizuki, M., Okano, Y., Hama, N., Tojo, T., Asakura, H., Kumai, K., Ishibiki, K., Hosoda, Y. & Homma, M., 1988 Sep, In : Clinical Rheumatology. 7, 3, p. 394-397 4 p.

Research output: Contribution to journalArticle

Pyloric Stenosis
Diffuse Scleroderma
Duodenum
Edema
Stomach
1990
55 Citations (Scopus)

Isolation and phosphorylation of the Bacillus subtilis degS and degU gene products

Mukai, K., Kawata, M. & Tanaka, T., 1990 Nov 15, In : Journal of Biological Chemistry. 265, 32, p. 20000-20006 7 p.

Research output: Contribution to journalArticle

Phosphorylation
Bacilli
Bacillus subtilis
Genes
Phosphates
1991
1 Citation (Scopus)

Analysis of free radical production by fluorescent probes in CCL4-induced liver injury

Kato, S., Suematsu, M., Suzuki, H., Ishii, H. & Tsuchiya, M., 1991, In : Journal of Toxicological Sciences. 16, SUPPL. 2, p. 79-82 4 p.

Research output: Contribution to journalArticle

Fluorescent Dyes
Liver
Free Radicals
12 Citations (Scopus)

Repeated intestinal ulcerations in a patient with systemic lupus erythematosus and high serum antiphospholipid antibody levels

Sasamura, H., Nakamoto, H., Ryuzaki, M., Kumagai, K., Abe, S., Suzuki, H., Hirakata, M., Tojo, T., Handa, M., Yamamoto, M., Teramoto, T., Hosoda, Y. & Saruta, T., 1991, In : Southern Medical Journal. 84, 4, p. 515-516 2 p.

Research output: Contribution to journalArticle

Antiphospholipid Antibodies
Systemic Lupus Erythematosus
Serum
Prothrombin Time
Vasculitis
26 Citations (Scopus)

Structural differences in 5′-flanking regions of rat cytochrome P-450aldo and P-45011β genes

Mukai, K., Imai, M., Shimada, H., Okada, Y., Ogishima, T. & Ishimura, Y., 1991 Nov 14, In : Biochemical and Biophysical Research Communications. 180, 3, p. 1187-1193 7 p.

Research output: Contribution to journalArticle

5' Flanking Region
Cytochromes
Rats
Genes
Nuclease Protection Assays
1992

A 75-year-old woman with longstanding hypertension, resulting in congestive heart failure and renal failure.

Handa, S., Yoshikawa, T., Kondoh, T., Wakui, M., Suzuki, H., Yuasa, Y., Kameyama, K. & Hata, J., 1992 Mar, In : Keio Journal of Medicine. 41, 1, p. 33-39 7 p.

Research output: Contribution to journalArticle

Takayasu Arteritis
Pulmonary Edema
Chronic Kidney Failure
Renal Insufficiency
Heart Failure
113 Citations (Scopus)

Autoantibodies to small nuclear and cytoplasmic ribonucleoproteins in Japanese patients with inflammatory muscle disease

Hirakata, M., Mimori, T., Akizuki, M., Craft, J., Hardin, J. A. & Homma, M., 1992 Apr, In : Arthritis and Rheumatism. 35, 4, p. 449-456 8 p.

Research output: Contribution to journalArticle

Small Cytoplasmic Ribonucleoproteins
Small Nuclear Ribonucleoproteins
Myositis
Autoantibodies
Dermatomyositis
77 Citations (Scopus)

Early midzonal oxidative stress preceding cell death in hypoperfused rat liver

Suematsu, M., Suzuki, H., Ishii, H., Kato, S., Yanagisawa, T., Asako, H., Suzuki, M. & Tsuchiya, M., 1992, In : Gastroenterology. 103, 3, p. 994-1001 8 p.

Research output: Contribution to journalArticle

Oxidative Stress
Cell Death
Propidium
Liver
Hydrogen Peroxide
73 Citations (Scopus)

Effect of rat CINC/gro, a member of the interleukin-8 family, on leukocytes in microcirculation of the rat mesentery

Watanabe, K., Suematsu, M., Iida, M., Takaishi, K., Iizuka, Y., Suzuki, H., Suzuki, M., Tsuchiya, M. & Tsurufuji, S., 1992, In : Experimental and Molecular Pathology. 56, 1, p. 60-69 10 p.

Research output: Contribution to journalArticle

Microcirculation
Mesentery
Chemotactic Factors
Interleukin-8
Rats

Enzyme-linked immunosorbent assay of anti-Ku antibodies using purified recombinant Ku antigens

Suwa, A., Mimori, T., Hama, N., Fujii, T., Hirakata, M., Ohosone, Y., Akizuki, M. & Homma, M., 1992, In : Japanese Journal of Clinical Immunology. 15, 4, p. 337-345 9 p.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Enzyme-Linked Immunosorbent Assay
Galactosidases
Polymyositis
Recombinant Fusion Proteins
194 Citations (Scopus)

Helicobacter pylori-associated ammonia production enhances neutrophil- dependent gastric mucosal cell injury

Suzuki, M., Miura, S., Suematsu, M., Fukumura, D., Kurose, I., Suzuki, H., Kai, A., Kudoh, Y., Ohashi, M. & Tsuchiya, M., 1992, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 263, 5 26-5

Research output: Contribution to journalArticle

Ammonia
Helicobacter pylori
Stomach
Neutrophils
Wounds and Injuries
9 Citations (Scopus)

Quantitative analysis of mesenteric microcirculatory disturbances induced by autonomic nervous irritation.

Liu, Y. Y., Miura, S., Suzuki, H., Kurose, I., Fukumura, D., Suzuki, M., Suematsu, M. & Tsuchiya, M., 1992 Sep, In : Keio Journal of Medicine. 41, 3, p. 128-133 6 p.

Research output: Contribution to journalArticle

Venules
Arterioles
Electric Stimulation
Permeability
Autonomic Pathways
8 Citations (Scopus)

Spontaneous remission of dermatomyositis which developed one month after normal delivery

Suwa, A., Hirakata, M., Tsuzaka, K., Hama, N., Fujii, T., Mimori, T. & Akizuki, M., 1992, In : Ryumachi. 32, 1, p. 73-79 7 p.

Research output: Contribution to journalArticle

Puerperal Disorders
Spontaneous Remission
Dermatomyositis
Pregnancy

The use of digital imaging photonic microscopy to investigate oxygen-derived free radicals in microcirculatory disturbances

Tsuchiya, M., Suzuki, H. & Suematsu, M., 1992, In : Japanese Journal of Plastic and Reconstructive Surgery. 35, 10, p. 1059-1065 7 p.

Research output: Contribution to journalArticle

Optics and Photonics
Free Radicals
Microscopy
Oxygen
1993
24 Citations (Scopus)

Helicobacter pylori elicits gastric mucosal cell damage associated with neutrophil-derived toxic oxidants

Suzuki, M., Miura, S., Suematsu, M., Fukumura, D., Suzuki, H., Kai, A. & Tsuchiya, M., 1993, In : European Journal of Gastroenterology and Hepatology. 5, SUPPL. 1

Research output: Contribution to journalArticle

Poisons
Oxidants
Helicobacter pylori
Stomach
Neutrophils
50 Citations (Scopus)

Intravital and Electron Microscopic Observation of Ito Cells in Rat Hepatic Microcirculation

Suematsu, M., Oda, M., Suzuki, H., Kaneko, H., Watanabe, N., Furusho, T., Masushige, S. & Tsuchiya, M., 1993 Jul, In : Microvascular Research. 46, 1, p. 28-42 15 p.

Research output: Contribution to journalArticle

Microcirculation
Hepatic Stellate Cells
Rats
Vitamin A
Electrons
65 Citations (Scopus)

Isolation and characterization of rat CYP11B genes involved in late steps of mineralo- and glucocorticoid syntheses

Mukai, K., Imai, M., Shimada, H. & Ishimura, Y., 1993 Apr 25, In : Journal of Biological Chemistry. 268, 12, p. 9130-9137 8 p.

Research output: Contribution to journalArticle

Steroid 11-beta-Hydroxylase
Mineralocorticoids
Glucocorticoids
Rats
Cytochrome P-450 CYP11B2
21 Citations (Scopus)

Xanthine oxidase-mediated intracellular oxidative stress in response to cerulein in rat pancreatic acinar cells

Suzuki, H., Suematsu, M., Miura, S., Asako, H., Kurose, I., Ishii, H., Houzawa, S. & Tsuchiya, M., 1993, In : Pancreas. 8, 4, p. 465-470 6 p.

Research output: Contribution to journalArticle

Ceruletide
Xanthine Oxidase
Acinar Cells
Oxidative Stress
Fluorescence
1994
71 Citations (Scopus)

Autoantibodies to RNA polymerase II are common in systemic lupus erythematosus and overlap syndrome: Specific recognition of the phosphorylated (IIO) form by a subset of human sera

Satoh, M., Ajmani, A. K., Ogasawara, T., Langdon, J. J., Hirakata, M., Wang, J. & Reeves, W. H., 1994 Nov, In : Journal of Clinical Investigation. 94, 5, p. 1981-1989 9 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Systemic Lupus Erythematosus
Autoantibodies
Systemic Scleroderma
RNA Polymerase I
209 Citations (Scopus)

Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells

Kawasaki, M., Uchida, S., Monkawa, T., Miyawaki, A., Mikoshiba, K., Marumo, F. & Sasaki, S., 1994, In : Neuron. 12, 3, p. 597-604 8 p.

Research output: Contribution to journalArticle

Chloride Channels
Protein Kinase C
Organism Cloning
Brain
Amino Acids
160 Citations (Scopus)

DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA

Suwa, A., Hirakata, M., Takeda, Y., Jesch, S. A., Mimori, T. & Hardin, J. A., 1994 Jul 19, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 15, p. 6904-6908 5 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
DNA
Holoenzymes
Autoantigens
Cell Extracts
157 Citations (Scopus)

Expression and distribution of aquaporin of collecting duct are regulated by vasopressin V2 receptor in rat kidney

Hayashi, M., Sasaki, S., Tsuganezawa, H., Monkawa, T., Kitajima, W., Konishi, K., Fushimi, K., Marumo, F. & Saruta, T., 1994 Nov, In : Journal of Clinical Investigation. 94, 5, p. 1778-1783 6 p.

Research output: Contribution to journalArticle

Vasopressin Receptors
Aquaporins
Kidney
Dehydration
Osmolar Concentration
12 Citations (Scopus)

Gastric Mucosal Injury: Microcirculation and Helicobacter Pylori

Suzuki, H., Miura, S., Nakamura, M. & Tsuchiya, M., 1994, In : The Keio journal of medicine. 43, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Autonomic Nervous System
Microcirculation
Helicobacter pylori
Stomach
Wounds and Injuries
72 Citations (Scopus)

In vivo visualization of oxygen radical-dependent photoemission

Tsuchiya, M., Suematsu, M. & Suzuki, H., 1994, In : Methods in Enzymology. 233, p. 128-140 13 p.

Research output: Contribution to journalArticle

Photoemission
Reactive Oxygen Species
Visualization
Oxidants
Tissue
41 Citations (Scopus)

Rat ClNC/gro: A novel mediator for locomotive and secretagogue activation of neutrophils in vivo

Suzuki, H., Suematsu, M., Miura, S., Liu, Y. Y., Watanabe, K., Miyasaka, M., Tsurufuji, S. & Tsuchiya, M., 1994, In : Journal of Leukocyte Biology. 55, 5, p. 652-657 6 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Luminol
Neutrophils
Luminescence
Endothelium
Type I DNA Topoisomerase
Systemic Scleroderma
Epitopes
Lung
Observation
100 Citations (Scopus)

Rebamipide, a novel antiulcer agent, attenuates Helicobacter pylori induced gastric mucosal cell injury associated with neutrophil derived oxidants

Suzuki, M., Miura, S., Mori, M., Kai, A., Suzuki, H., Fukumura, D., Suematsu, M. & Tsuchiya, M., 1994 Oct, In : Gut. 35, 10, p. 1375-1378 4 p.

Research output: Contribution to journalArticle

Oxidants
Helicobacter pylori
Pylorus
Stomach
Neutrophils
3 Citations (Scopus)

Sulfhydryl blocker-induced colitis in the rat: Immunological changes in thymus gland and colonic mucosa

Suzuki, H., Hibi, T., Oda, M., Hosoda, Y., Mori, M., Miura, S., Tanaka, S., Watanabe, M. & Tscuhiya, M., 1994, In : Journal of Gastroenterology and Hepatology (Australia). 9, 6, p. 544-550 7 p.

Research output: Contribution to journalArticle

Ethylmaleimide
Colitis
Thymus Gland
Mucous Membrane
Colon
8 Citations (Scopus)

Verotoxin induces hemorrhagic lesions in rat small intestine - Temporal alteration of vasoactive substances

Tashiro, H., Miura, S., Kurose, I., Fukumura, D., Suzuki, H., Suematsu, M., Yoshioka, M., Tsuchiya, M., Kai, A. & Kudoh, Y., 1994 Jun, In : Digestive Diseases and Sciences. 39, 6, p. 1230-1238 9 p.

Research output: Contribution to journalArticle

Shiga Toxins
Platelet Activating Factor
Small Intestine
Neutrophils
Escherichia coli O157
1995
1 Citation (Scopus)

A case of rheumatoid arthritis complicated with salazosulfapyridine-induced aplastic anemia

Suwa, A., Kawai, S., Hirakata, M., Hirakata, M. & Inada, S., 1995 Feb, In : Nihon Rinsho Men"eki Gakkai kaishi = Japanese journal of clinical immunology. 18, 1, p. 116-122 7 p.

Research output: Contribution to journalArticle

Sulfasalazine
Aplastic Anemia
Rheumatoid Arthritis
Blood Cell Count
Testosterone Congeners
185 Citations (Scopus)

Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits

Monkawa, T., Miyawaki, A., Sugiyama, T., Yoneshima, H., Yamamoto-Hino, M., Furuichi, T., Saruta, T., Hasegawa, M. & Mikoshiba, K., 1995 Jun 16, In : Journal of Biological Chemistry. 270, 24, p. 14700-14704 5 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
CHO Cells
Cells
Cell Line
Inositol 1,4,5-Trisphosphate
7 Citations (Scopus)

Inhibitions of platelet-activating factor production and granulocyte oxidative activation by Rikkunshi-To in the process of gastric mucosal injury

Kurose, I., Miura, S., Fukumura, D., Suzuki, H., Tsuchiya, M. & Ishii, H., 1995, In : Pathophysiology. 2, 3, p. 153-159 7 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Granulocytes
Stomach
Electric Stimulation
Luminol
9 Citations (Scopus)

Interstitial lung disease in patients with connective tissue diseases

Hirakata, M., Nakamura, K., Kaburaki, J., Suwa, A., Mimori, T., Kanazawa, M. & Akizuki, M., 1995 Dec, In : Nihon Kyōbu Shikkan Gakkai zasshi. 33 Suppl, p. 268-276 9 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Interstitial Lung Diseases
Dermatomyositis
Amino Acyl-tRNA Synthetases
Systemic Lupus Erythematosus
32 Citations (Scopus)

Involvement of an AP-1 complex in zone-specific expression of the CYP11B1 gene in the rat adrenal cortex

Mukai, K., Mitani, F., Shimada, H. & Ishimura, Y., 1995, In : Molecular and Cellular Biology. 15, 11, p. 6003-6012 10 p.

Research output: Contribution to journalArticle

Steroid 11-beta-Hydroxylase
Adrenal Cortex
Transcription Factor AP-1
Steroidogenic Factor 1
Zona Fasciculata
35 Citations (Scopus)

Massive pericardial effusion in scleroderma: A review of five cases

Satoh, M., Tokuhira, M., Hama, N., Hirakata, M., Kuwana, M., Akizuki, M., Ichikawa, Y., Ogawa, S. & Homma, M., 1995 Jun, In : Rheumatology. 34, 6, p. 564-567 4 p.

Research output: Contribution to journalArticle

Scleroderma
Pericarditis
Pericardial Effusion
Blood
blood cell count
43 Citations (Scopus)

Substance P induces degranulation of mast cells and leukocyte adhesion to venular endothelium

Suzuki, H., Miura, S., Liu, Y. Y., Tsuchiya, M. & Ishii, H., 1995, In : Peptides. 16, 8, p. 1447-1452 6 p.

Research output: Contribution to journalArticle

Substance P
Mast Cells
Cell Adhesion
Endothelium
Leukocytes
6 Citations (Scopus)

Three cases with systemic rheumatic diseases who developed pulmonary lesions suggestive of bronchiolitis obliterans organizing pneumonia

Nakamura, K., Hirakata, M., Fujii, T., Yoshida, T., Mimori, T., Mukai, M. & Akizuki, M., 1995, In : Ryumachi. 35, 1, p. 9-14 6 p.

Research output: Contribution to journalArticle

Cryptogenic Organizing Pneumonia
Rheumatic Diseases
Lung
Lung Diseases
Prednisolone
1996
17 Citations (Scopus)

Anti-U5 small nuclear ribonucleoprotein (snRNP) antibodies: A rare anti-U snRNP specificity

Okano, Y., Targoff, I. N., Oddis, C. V., Fujii, T., Kuwana, M., Tsuzaka, K., Hirakata, M., Mimori, T., Craft, J. & Medsger, T. A., 1996 Oct, In : Clinical Immunology and Immunopathology. 81, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

U5 Small Nuclear Ribonucleoproteins
Small Nuclear Ribonucleoproteins
Antibodies
Serum
Connective Tissue Diseases
29 Citations (Scopus)

Autoantibodies to DNA-dependent protein kinase probes for the catalytic subunit

Suwa, A., Hirakata, M., Takeda, Y., Okano, Y., Mimori, T., Inada, S., Watanabe, F., Teraoka, H., Dynan, W. S. & Hardin, J. A., 1996 Mar 15, In : Journal of Clinical Investigation. 97, 6, p. 1417-1421 5 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Autoantibodies
Catalytic Domain
DNA
Serum
28 Citations (Scopus)

Autoantibodies to glycyl-transfer RNA synthetase in myositis

Hirakata, M., Suwa, A., Takeda, Y., Matsuoka, Y., Irimajiri, S., Targoff, I. N., Hardin, J. A. & Craft, J., 1996 Jan, In : Arthritis and Rheumatism. 39, 1, p. 146-151 6 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Myositis
Autoantibodies
Antibodies
Aminoacylation
4 Citations (Scopus)

Autoimmunity to RNA polymerase II is focused at the carboxyl terminal domain of the large subunit

Hirakata, M., Kanungo, J., Suwa, A., Takeda, Y., Craft, J. & Hardin, J. A., 1996 Nov, In : Arthritis and Rheumatism. 39, 11, p. 1886-1891 6 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Autoimmunity
Autoantigens
Peptides
Serum
3 Citations (Scopus)

Case of MPO-ANCA positive interstitial pneumonitis and necrotizing, crescentic glomerulonephritis

Chikaraishi, A., Ohosone, Y., Kameda, H., Nakamura, K., Ogasawara, T., Hirakata, M., Konishi, K., Kuramochi, S., Mimori, T. & Ikeda, Y., 1996, In : Ryumachi. 36, 6, p. 869-873 5 p.

Research output: Contribution to journalArticle

Antineutrophil Cytoplasmic Antibodies
Interstitial Lung Diseases
Glomerulonephritis
Intermittent Claudication
Rheumatoid Factor
16 Citations (Scopus)

Chronic ethanol consumption enhances endotoxin induced hepatic sinusoidal leukocyte adhesion

Ohki, E., Kato, S., Horie, Y., Mizukami, T., Tamai, H., Yokoyama, H., Ito, D., Fukuda, M., Suzuki, H., Kurose, I. & Ishii, H., 1996, In : Alcoholism: Clinical and Experimental Research. 20, 9 SUPPL.

Research output: Contribution to journalArticle

Endotoxins
Rats
Leukocytes
Ethanol
Adhesion
7 Citations (Scopus)
Amino Acyl-tRNA Synthetases
Interstitial Lung Diseases
Immunoprecipitation
Autoantibodies
Muscles
5 Citations (Scopus)

Data on high-performance thin-layer chromatography of analgesic and antipyretic drugs

Shinozuka, T., Terada, M., Ogamo, A., Nakajima, R., Takei, S., Murai, T., Wakasugi, C. & Yanagida, J., 1996, In : Japanese Journal of Forensic Toxicology. 14, 3, p. 246-252 7 p.

Research output: Contribution to journalArticle

Thin layer chromatography
Antipyretics
Thin Layer Chromatography
Phenylbutazone
Analgesics
30 Citations (Scopus)

Effects of long term stimulation of ACTH- and angiotensin II-secretions on the rat adrenal cortex

Mitani, F., Miyamoto, H., Mukai, K. & Ishimura, Y., 1996, In : Endocrine Research. 22, 4, p. 421-431 11 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Angiotensin II
Adrenocorticotropic Hormone
Zona Glomerulosa
Cytochrome P-450 CYP11B2
48 Citations (Scopus)

Enhanced levels of chemiluminescence and platelet activating factor in urease-positive gastric ulcers

Suzuki, H., Miura, S., Imaeda, H., Suzuki, M., Han, J. Y., Mori, M., Fukumura, D., Tsuchiya, M. & Ishii, H., 1996, In : Free Radical Biology and Medicine. 20, 3, p. 449-454 6 p.

Research output: Contribution to journalArticle

Chemiluminescence
Urease
Platelet Activating Factor
Stomach Ulcer
Luminescence
10 Citations (Scopus)

Identification of a DRB1*0405 variant (DRB1*04052) using the PCR-RFLP method

Moribe, T., Kaneshige, T., Hirakata, M., Mimori, T., Akitsuki, M. & Inoko, H., 1996, In : Tissue Antigens. 47, 5, p. 450-453 4 p.

Research output: Contribution to journalArticle

Nucleic Acid Sequence Homology
Molecular Sequence Data
MHC Class II Genes
Sequence Alignment
HLA-DR Antigens