Medical Education Center

Research Output 1986 2019

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2010

[Anti-Ku antibodies].

Hirakata, M. & Suwa, A., 2010 Jun, In : Nippon rinsho. Japanese journal of clinical medicine. 68 Suppl 6, p. 572-574 3 p.

Research output: Contribution to journalArticle

Specimen Handling
Polymyositis
Nuclear Antigens
Systemic Scleroderma
Immunodiffusion

[Anti-PL-7, anti-PL-12, and other anti-aminoacyl tRNA synthetase antibodies].

Hirakata, M., 2010 Jun, In : Nippon rinsho. Japanese journal of clinical medicine. 68 Suppl 6, p. 555-559 5 p.

Research output: Contribution to journalArticle

Threonine-tRNA Ligase
Alanine-tRNA Ligase
Histidine-tRNA Ligase
Specimen Handling
Amino Acyl-tRNA Synthetases
21 Citations (Scopus)

Acid suppression by proton pump inhibitors enhances aquaporin-4 and KCNQ1 expression in gastric fundic parietal cells in mouse

Matsuzaki, J., Suzuki, H., Minegishi, Y., Sugai, E., Tsugawa, H., Yasui, M. & Hibi, T., 2010 Dec, In : Digestive Diseases and Sciences. 55, 12, p. 3339-3348 10 p.

Research output: Contribution to journalArticle

Gastric Parietal Cells
Aquaporin 4
Proton Pump Inhibitors
Lansoprazole
Acids
20 Citations (Scopus)

Acotiamide (Z-338) as a possible candidate for the treatment of functional dyspepsia

Suzuki, H. & Hibi, T., 2010 Jun, In : Neurogastroenterology and Motility. 22, 6, p. 595-599 5 p.

Research output: Contribution to journalArticle

Dyspepsia
Gastric Emptying
Gastrointestinal Motility
Therapeutics
Gastrointestinal Agents
154 Citations (Scopus)

Adrenocortical zonation in humans under normal and pathological conditions

Nishimoto, K., Nakagawa, K., Li, D., Kosaka, T., Oya, M., Mikami, S., Shibata, H., Itoh, H., Mitani, F., Yamazaki, T., Ogishima, T., Suematsu, M. & Mukai, K., 2010 May, In : Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2296-2305 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Steroid 11-beta-Hydroxylase
Aldosterone
Adenoma
Enzymes
6 Citations (Scopus)

Autofluorescence videoendoscopy system using the SAFE-3000 for assessing superficial gastric neoplasia

Imaeda, H., Hosoe, N., Kashiwagi, K., Ida, Y., Saito, Y., Suzuki, H., Aiura, K., Ogata, H., Kumai, K. & Hibi, T., 2010, In : Journal of Gastroenterology and Hepatology (Australia). 25, 4, p. 706-711 6 p.

Research output: Contribution to journalArticle

Stomach
Stomach Neoplasms
Adenoma
Neoplasms
Color
3 Citations (Scopus)

Clinical associations with autoantibody reactivities to individual components of U1 small nuclear ribonucleoprotein

Kaneko, Y., Suwa, A., Hirakata, M., Ikeda, Y. & Kuwana, M., 2010 Mar, In : Lupus. 19, 3, p. 307-312 6 p.

Research output: Contribution to journalArticle

U1 Small Nuclear Ribonucleoproteins
Autoantibodies
Antibodies
Connective Tissue Diseases
Small Nuclear Ribonucleoproteins
5 Citations (Scopus)

Clinical results of observation of the upper gastrointestinal tract by transgastrostomic endoscopy using an ultrathin endoscope

Imaeda, H., Hosoe, N., Nakamizo, H., Kashiwagi, K., Suzuki, H., Saito, Y., Suganuma, K., Ida, Y., Matsuzaki, J., Iwasaki, E., Iwao, Y., Ogata, H. & Hibi, T., 2010, In : Journal of Gastroenterology and Hepatology (Australia). 25, 12, p. 1850-1854 5 p.

Research output: Contribution to journalArticle

Upper Gastrointestinal Tract
Gastrostomy
Endoscopes
Endoscopy
Observation
36 Citations (Scopus)

Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption in patients with severe heart failure

Baba, A., Akaishi, M., Shimada, M., Monkawa, T., Wakabayashi, Y., Takahashi, M., Nagatomo, Y. & Yoshikawa, T., 2010, In : Circulation Journal. 74, 7, p. 1372-1378 7 p.

Research output: Contribution to journalArticle

Autoantibodies
Heart Failure
Immunoglobulin G
Stroke Volume
Blood Component Removal
62 Citations (Scopus)

Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori

Hirata, K., Suzuki, H., Nishizawa, T., Tsugawa, H., Muraoka, H., Saito, Y., Matsuzaki, J. & Hibi, T., 2010, In : Journal of Gastroenterology and Hepatology (Australia). 25, SUPPL. 1

Research output: Contribution to journalArticle

Clarithromycin
Helicobacter pylori
Point Mutation
Drug Resistance
Messenger RNA
23 Citations (Scopus)

Delayed gastric emptying and disruption of the interstitial cells of Cajal network after gastric ischaemia and reperfusion

Suzuki, S., Suzuki, H., Horiguchi, K., Tsugawa, H., Matsuzaki, J., Takagi, T., Shimojima, N. & Hibi, T., 2010 May, In : Neurogastroenterology and Motility. 22, 5

Research output: Contribution to journalArticle

Interstitial Cells of Cajal
Gastric Emptying
Reperfusion
Stomach
Ischemia
30 Citations (Scopus)

Fibroblast expression of an IκB dominant-negative transgene attenuates renal fibrosis

Inoue, T., Takenaka, T., Hayashi, M., Monkawa, T., Yoshino, J., Shimoda, K., Neilson, E. G., Suzuki, H. & Okada, H., 2010 Dec, In : Journal of the American Society of Nephrology. 21, 12, p. 2047-2052 6 p.

Research output: Contribution to journalArticle

Transgenes
Fibrosis
Fibroblasts
Kidney
Epithelium
10 Citations (Scopus)

Gallstones increase the prevalence of Barrett's esophagus

Matsuzaki, J., Suzuki, H., Asakura, K., Saito, Y., Hirata, K., Takebayashi, T. & Hibi, T., 2010 Feb, In : Journal of Gastroenterology. 45, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Metaplasia
Gallstones
Odds Ratio
Confidence Intervals
15 Citations (Scopus)

H. pylori-eradication therapy increases RUNX3 expression in the glandular epithelial cells in enlarged-fold gastritis

Suzuki, M., Suzuki, H., Minegishi, Y., Ito, K., Nishizawa, T. & Hibi, T., 2010 May, In : Journal of Clinical Biochemistry and Nutrition. 46, 3, p. 259-264 6 p.

Research output: Contribution to journalArticle

Oxidative stress
Pylorus
Gastritis
Helicobacter pylori
Epithelial Cells
79 Citations (Scopus)

Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents

Kanazawa, H., Ieda, M., Kimura, K., Arai, T., Kawaguchi-Manabe, H., Matsuhashi, T., Endo, J., Sano, M., Kawakami, T., Kimura, T., Monkawa, T., Hayashi, M., Iwanami, A., Okano, H., Okada, Y., Ishibashi-Ueda, H., Ogawa, S. & Fukuda, K., 2010 Feb 1, In : Journal of Clinical Investigation. 120, 2, p. 408-421 14 p.

Research output: Contribution to journalArticle

Sympathetic Nervous System
Cholinergic Agents
Rodentia
Heart Failure
Cytokines
75 Citations (Scopus)

Helicobacter pylori eradication therapy

Suzuki, H., Nishizawa, T. & Hibi, T., 2010 Apr, In : Future Microbiology. 5, 4, p. 639-648 10 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Proton Pump Inhibitors
Amoxicillin
Metronidazole
Clarithromycin
12 Citations (Scopus)

Homology model of the DNA gyrase enzyme of Helicobacter pylori, a target of quinolone-based eradication therapy

Matsuzaki, J., Suzuki, H., Tsugawa, H., Nishizawa, T. & Hibi, T., 2010, In : Journal of Gastroenterology and Hepatology (Australia). 25, SUPPL. 1

Research output: Contribution to journalArticle

DNA Gyrase
Quinolones
Helicobacter pylori
Enzymes
Therapeutics
10 Citations (Scopus)

Ileal Mucosa-Associated Lymphoid Tissue (MALT) lymphoma with a large-cell component that regressed spontaneously

Makino, Y., Suzuki, H., Nishizawa, T., Kameyama, K., Hisamatsu, T., Imaeda, H., Mukai, M. & Hibi, T., 2010 Mar, In : Gut and Liver. 4, 1, p. 117-121 5 p.

Research output: Contribution to journalArticle

Marginal Zone B-Cell Lymphoma
Cellular Structures
Ileum
Non-Hodgkin's Lymphoma
Language
8 Citations (Scopus)

Partial regression of duodenal lesions of intestinal follicular lymphoma after antibiotic treatment

Yaguchi, T., Imaeda, H., Kizaki, M., Hosoe, N., Suzuki, H., Ogata, H., Iwao, Y., Kameyama, K., Ikeda, Y. & Hibi, T., 2010 Oct, In : Digestive Endoscopy. 22, 4, p. 316-318 3 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Anti-Bacterial Agents
Duodenum
Endoscopy
Lymphoma
7 Citations (Scopus)

Serum lipid levels are positively associated with non-erosive reflux disease, but not with functional heartburn

Matsuzaki, J., Suzuki, H., Iwasaki, E., Yokoyama, H., Sugino, Y. & Hibi, T., 2010 Sep, In : Neurogastroenterology and Motility. 22, 9

Research output: Contribution to journalArticle

Heartburn
Gastroesophageal Reflux
Lipids
Serum
Esophagitis
65 Citations (Scopus)

The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the japanese population

Shimane, K., Kochi, Y., Horita, T., Ikari, K., Amano, H., Hirakata, M., Okamoto, A., Yamada, R., Myouzen, K., Suzuki, A., Kubo, M., Atsumi, T., Koike, T., Takasaki, Y., Momohara, S., Yamanaka, H., Nakamura, Y. & Yamamoto, K., 2010 Feb, In : Arthritis and Rheumatism. 62, 2, p. 574-579 6 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Single Nucleotide Polymorphism
Rheumatoid Arthritis
Population
Genome-Wide Association Study
2009
8 Citations (Scopus)

Caudal regression and tracheoesophageal malformation induced by adriamycin: A novel chick model of vater association

Naito, Y., Kimura, T., Aramaki, M., Izumi, K., Okada, Y., Suzuki, H., Takahashi, T. & Kosaki, K., 2009 Jun, In : Pediatric Research. 65, 6, p. 607-612 6 p.

Research output: Contribution to journalArticle

Doxorubicin
Embryonic Structures
Egg White
Lymphocyte Activation
Cell Division
143 Citations (Scopus)

Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells

Saito, Y., Suzuki, H., Tsugawa, H., Nakagawa, I., Matsuzaki, J., Kanai, Y. & Hibi, T., 2009 Jul 30, In : Oncogene. 28, 30, p. 2738-2744 7 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
MicroRNAs
Epigenomics
Stomach Neoplasms
Down-Regulation
42 Citations (Scopus)

Clinical and histopathological features of myopathies in Japanese patients with anti-SRP autoantibodies

Takada, T., Hirakata, M., Suwa, A., Kaneko, Y., Kuwana, M., Ishihara, T. & Ikeda, Y., 2009, In : Modern Rheumatology. 19, 2, p. 156-164 9 p.

Research output: Contribution to journalArticle

Signal Recognition Particle
Muscular Diseases
Autoantibodies
Myositis
Staining and Labeling
5 Citations (Scopus)

Clinical results of endoscopic hemostasis using a short transparent hood and short hemoclips for non-variceal upper gastrointestinal bleeding: Original article

Hosoe, N., Imaeda, H., Kashiwagi, K., Naganuma, M., Inoue, N., Suzuki, H., Suganuma, K., Ida, Y., Nakamizo, H., Aiura, K., Ogata, H., Iwao, Y., Kumai, K. & Hibi, T., 2009 Apr, In : Digestive Endoscopy. 21, 2, p. 93-96 4 p.

Research output: Contribution to journalArticle

Endoscopic Hemostasis
Surgical Instruments
Hemostasis
Hemorrhage
Endoscopes
83 Citations (Scopus)

Differentiation of murine embryonic stem and induced pluripotent stem cells to renal lineage in vitro

Morizane, R., Monkawa, T. & Itoh, H., 2009 Dec 25, In : Biochemical and Biophysical Research Communications. 390, 4, p. 1334-1339 6 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Stem cells
Kidney
Embryonic Stem Cells
Activins
27 Citations (Scopus)

Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of mongolian gerbils

Nishizawa, T., Suzuki, H., Nakagawa, I., Minegishi, Y., Masaoka, T., Iwasaki, E. & Hibi, T., 2009 Apr, In : Digestion. 79, 2, p. 99-108 10 p.

Research output: Contribution to journalArticle

Hedgehogs
Gerbillinae
Gastric Mucosa
Helicobacter pylori
Stomach
1 Citation (Scopus)

Erratum: Clinical and histopathological features of myopathies in Japanese patients with anti-SRP autoantibodies (Modern Rheumatology 10.1007/s10165-008-0139-8)

Takada, T., Hirakata, M., Suwa, A., Kaneko, Y., Kuwana, M., Ishihara, T. & Ikeda, Y., 2009, In : Modern Rheumatology. 19, 2, p. 165 1 p.

Research output: Contribution to journalArticle

Rheumatology
Muscular Diseases
Autoantibodies
81 Citations (Scopus)

Helicobacter pylori and gastric cancer

Suzuki, H., Iwasaki, E. & Hibi, T., 2009 Jun, In : Gastric Cancer. 12, 2, p. 79-87 9 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Stomach Neoplasms
Nobel Prize
Peptic Ulcer
Bacterial Infections
33 Citations (Scopus)
Marginal Zone B-Cell Lymphoma
Gastric Mucosa
Helicobacter pylori
Therapeutics
Non-Hodgkin's Lymphoma
12 Citations (Scopus)

Helicobacter pylori and microcirculation

Suzuki, H., Suzuki, M., Imaeda, H. & Hibi, T., 2009, In : Microcirculation. 16, 7, p. 547-558 12 p.

Research output: Contribution to journalArticle

Microcirculation
Helicobacter pylori
Helicobacter Infections
Stomach
Bacteria
77 Citations (Scopus)

Japanese herbal medicine in functional gastrointestinal disorders

Suzuki, H., Inadomi, J. M. & Hibi, T., 2009 Jul, In : Neurogastroenterology and Motility. 21, 7, p. 688-696 9 p.

Research output: Contribution to journalArticle

Herbal Medicine
Gastrointestinal Diseases
Aptitude
Ileus
Dyspepsia
2 Citations (Scopus)

Lifestyle-related diseases and H. pylori

Suzuki, H., Matsuzaki, J. & Hibi, T., 2009 Dec, In : Nippon rinsho. Japanese journal of clinical medicine. 67, 12, p. 2366-2371 6 p.

Research output: Contribution to journalArticle

Pylorus
Life Style
Infection
Cerebrovascular Disorders
Gastric Mucosa
27 Citations (Scopus)

Past rifampicin dosing determines rifabutin resistance of helicobacter pylori

Suzuki, S., Suzuki, H., Nishizawa, T., Kaneko, F., Ootani, S., Muraoka, H., Saito, Y., Kobayashi, I. & Hibi, T., 2009 Mar, In : Digestion. 79, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

Rifabutin
Rifampin
Helicobacter pylori
Microbial Sensitivity Tests
Chronic Disease Hospitals
47 Citations (Scopus)

Quinolone-based third-line therapy for Helicobacter pylori eradication

Nishizawa, T., Suzuki, H. & Hibi, T., 2009 Mar, In : Journal of Clinical Biochemistry and Nutrition. 44, 2, p. 119-124 6 p.

Research output: Contribution to journalArticle

Quinolones
Helicobacter pylori
Furazolidone
Rifabutin
Proton Pump Inhibitors
28 Citations (Scopus)

Rebamipide-promoted restoration of gastric mucosal sonic hedgehog expression after early helicobacter pylori eradication

Nishizawa, T., Suzuki, H., Nakagawa, I., Minegishi, Y., Masaoka, T., Iwasaki, E. & Hibi, T., 2009 Jun, In : Digestion. 79, 4, p. 259-262 4 p.

Research output: Contribution to journalArticle

Anti-Ulcer Agents
Hedgehog Proteins
Gerbillinae
Quinolones
Helicobacter Infections
21 Citations (Scopus)

Silent acid reflux and asthma control

Asano, K. & Suzuki, H., 2009 Apr 9, In : New England Journal of Medicine. 360, 15, p. 1551-1553 3 p.

Research output: Contribution to journalArticle

Omeprazole
Proton Pump Inhibitors
Gastroesophageal Reflux
Treatment Failure
Asthma
5 Citations (Scopus)

Successful treatment of refractory polymyositis with the immunosuppressant mizoribine: Case report

Suwa, A., Hirakata, M., Kaneko, Y., Sato, S., Suzuki, Y. & Kuwana, M., 2009, In : Clinical Rheumatology. 28, 2, p. 227-229 3 p.

Research output: Contribution to journalArticle

Polymyositis
Immunosuppressive Agents
Cell Proliferation
Antimetabolites
Cerebral Infarction
47 Citations (Scopus)

The role of microRNAs in gastrointestinal cancers

Saito, Y., Suzuki, H. & Hibi, T., 2009, In : Journal of Gastroenterology. 44, SUPPL. 19, p. 18-22 5 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
MicroRNAs
Small Untranslated RNA
Neoplasms
Chemoprevention
15 Citations (Scopus)

Tubulointerstitial nephritis antigen-like 1 is expressed in extraembryonic tissues and interacts with laminin 1 in the Reichert membrane at postimplantation in the mouse

Igarashi, T., Tajiri, Y., Sakurai, M., Sato, E., Li, D., Mukai, K., Suematsu, M., Fukui, E., Yoshizawa, M. & Matsumoto, H., 2009, In : Biology of Reproduction. 81, 5, p. 948-955 8 p.

Research output: Contribution to journalArticle

Interstitial Nephritis
Antigens
Membranes
Blastocyst
Lipocalin 1
2008
7 Citations (Scopus)

Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori

Tsugawa, H., Suzuki, H., Nakagawa, I., Nishizawa, T., Saito, Y., Suematsu, M. & Hibi, T., 2008 Nov 7, In : Biochemical and Biophysical Research Communications. 376, 1, p. 46-51 6 p.

Research output: Contribution to journalArticle

2-oxoglutarate synthase
Coenzyme A-Transferases
Salvaging
Helicobacter pylori
Energy Metabolism

Anti-aminoacyl tRNA synthetase autoantibodies and their clinical significance

Hirakata, M., 2008, In : Japanese Journal of Chest Diseases. 67, 5, p. 359-369 11 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Dermatomyositis
Interstitial Lung Diseases
Autoantibodies
76 Citations (Scopus)

Clinical and radiological features of pneumocystis pneumonia in patients with rheumatoid arthritis, in comparison with methotrexate pneumonitis and pneumocystis pneumonia in acquired immunodeficiency syndrome: A multicenter study

Tokuda, H., Sakai, F., Yamada, H., Johkoh, T., Imamura, A., Dohi, M., Hirakata, M., Yamada, T., Kamatani, N., Kikuchi, Y., Sugii, S., Takeuchi, T., Tateda, K. & Goto, H., 2008, In : Internal Medicine. 47, 10, p. 915-923 9 p.

Research output: Contribution to journalArticle

Pneumocystis Pneumonia
Methotrexate
Multicenter Studies
Rheumatoid Arthritis
Pneumonia
58 Citations (Scopus)

Clinical characteristics of cytomegalovirus infection in rheumatic diseases: Multicentre survey in a large patient population

Takizawa, Y., Inokuma, S., Tanaka, Y., Saito, K., Atsumi, T., Hirakata, M., Kameda, H., Hirohata, S., Kondo, H., Kumagai, S. & Tanaka, Y., 2008, In : Rheumatology. 47, 9, p. 1373-1378 6 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Rheumatic Diseases
Methylprednisolone
Immunosuppressive Agents
Population
13 Citations (Scopus)
Adiponectin
Gastroesophageal Reflux
X-Rays
Body Mass Index
Obesity
14 Citations (Scopus)

Gastric epithelial cell modality and proton pump inhibitor

Masaoka, T., Suzuki, H. & Hibi, T., 2008 May, In : Journal of Clinical Biochemistry and Nutrition. 42, 3, p. 191-196 6 p.

Research output: Contribution to journalArticle

Proton Pump Inhibitors
Tumors
Stomach
Animals
stomach
26 Citations (Scopus)

Gatifloxacin-based triple therapy as a third-line regimen for Helicobacter pylori eradication

Nishizawa, T., Suzuki, H., Nakagawa, I., Iwasaki, E., Masaoka, T. & Hibi, T., 2008, In : Journal of Gastroenterology and Hepatology (Australia). 23, SUPPL. 2

Research output: Contribution to journalArticle

Helicobacter pylori
Rabeprazole
Clarithromycin
Amoxicillin
Bacteria
90 Citations (Scopus)

Helicobacter pylori eradication shifts monocyte Fcγ receptor balance toward inhibitory FcγRIIB in immune thrombocytopenic purpura patients

Asahi, A., Nishimoto, T., Okazaki, Y., Suzuki, H., Masaoka, T., Kawakami, Y., Ikeda, Y. & Kuwana, M., 2008 Aug 1, In : Journal of Clinical Investigation. 118, 8, p. 2939-2949 11 p.

Research output: Contribution to journalArticle

Idiopathic Thrombocytopenic Purpura
Fc Receptors
Helicobacter pylori
Monocytes
Purpura
3 Citations (Scopus)

High incidence of dieulafoy's lesions in upper gastrointestinal bleeding associated with polyarteritis - Clinical examination of patients of polyarteritis nodosa with rapidly progressive glomerulonephritis

Ohara, T., Kanoh, Y., Taguma, Y., Hashimoto, H., Suzuki, H., Sakai, Y., Kondo, F., Kameyama, J. I., Tani, N., Yoshino, K. & Kitajima, M., 2008 May, In : Hepato-Gastroenterology. 55, 84, p. 821-825 5 p.

Research output: Contribution to journalArticle

Polyarteritis Nodosa
Glomerulonephritis
Hemorrhage
Incidence
Stomach Ulcer
7 Citations (Scopus)

Longterm effect of intermittent cyclical etidronate therapy on corticosteroid-induced osteoporosis in Japanese patients with connective tissue disease: 7-Year followup

Sato, S., Takada, T., Katsuki, Y., Kimura, N., Kaneko, Y., Suwa, A., Hirakata, M. & Kuwana, M., 2008 Jan, In : Journal of Rheumatology. 35, 1, p. 142-146 5 p.

Research output: Contribution to journalArticle

Etidronic Acid
Connective Tissue Diseases
Osteoporosis
Adrenal Cortex Hormones
Bone Density