Medical Education Center

Research Output 1986 2019

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2001
52 Citations (Scopus)

Dietary phosphorus deprivation induces 25-hydroxyvitamin D3 1α-hydroxylase gene expression

Yoshida, T., Yoshida, N., Monkawa, T., Hayashi, M. & Saruta, T., 2001, In : Endocrinology. 142, 5, p. 1720-1726 7 p.

Research output: Contribution to journalArticle

Dietary Phosphorus
Calcifediol
Mixed Function Oxygenases
Hypophosphatemia
Gene Expression
1 Citation (Scopus)
asparaginyl-tRNA synthetase
Transfer RNA
Autoantibodies
Substrates
Enzymes
3 Citations (Scopus)

Intravital demonstration of modulation of T lymphocyte migration by CINC/gro in rat Peyer's patches

Fujimori, H., Miura, S., Koseki, S., Hokari, R., Tsuzuki, Y., Komoto, S., Hara, Y., Suzuki, H., Serizawa, H. & Ishii, H., 2001, In : Digestion. 63, SUPPL. 1, p. 97-102 6 p.

Research output: Contribution to journalArticle

Peyer's Patches
T-Lymphocytes
Venules
Lymphocytes
Interleukin-8
15 Citations (Scopus)

Loading of mechanical pressure activates mitogen-activated protein kinase and early immediate gene in intestinal epithelial cells

Hirokawa, M., Miura, S., Kishikawa, H., Yoshida, H., Nakamizo, H., Higuchi, H., Nakatsumi, R. C., Suzuki, H., Saito, H. & Ishii, H., 2001, In : Digestive Diseases and Sciences. 46, 9, p. 1993-2003 11 p.

Research output: Contribution to journalArticle

Immediate-Early Genes
Mitogen-Activated Protein Kinases
Epithelial Cells
Pressure
Cell Proliferation
38 Citations (Scopus)

Polaprezinc attenuates the Helicobacter pylori-induced gastric mucosal leucocyte activation in Mongolian gerbils - A study using intravital videomicroscopy

Suzuki, H., Mori, M., Seto, K., Miyazawa, M., Kai, A., Suematsu, M., Yoneta, T., Miura, S. & Ishii, H., 2001, In : Alimentary Pharmacology and Therapeutics. 15, 5, p. 715-725 11 p.

Research output: Contribution to journalArticle

polaprezinc
Video Microscopy
Gerbillinae
Helicobacter pylori
Stomach
2000
1 Citation (Scopus)

A case of aortoduodenal fistula occurring after surgery and radiation for pancreatic cancer

Kitajima, M., Takahashi, S., Ueda, M., Hoshimoto, S., Koizumi, J., Matsumoto, K., Suzuki, H., Takeda, A., Kutsuki, S., Okita, H. & Hata, J. I., 2000 Mar, In : Keio Journal of Medicine. 49, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Celiac Artery
Fistula
Pathologic Constriction
Superior Mesenteric Artery
24 Citations (Scopus)

A case of polymyositis associated with hepatitis B infection

Nojima, T., Hirakata, M., Sato, S., Fujii, T., Suwa, A., Mimori, T. & Ikeda, Y., 2000, In : Clinical and Experimental Rheumatology. 18, 1, p. 86-88 3 p.

Research output: Contribution to journalArticle

Polymyositis
Myositis
Hepatitis B
Infection
Hepatitis

Antiphospholipid syndrome(APS)

Hirakata, M., 2000, In : Ryōikibetsu shōkōgun shirīzu. 30 Pt 5, p. 389-392 4 p.

Research output: Contribution to journalArticle

beta 2-Glycoprotein I
Lupus Coagulation Inhibitor
Habitual Abortion
Antiphospholipid Antibodies
Antiphospholipid Syndrome
6 Citations (Scopus)

Cell-specific expression of the IP3 receptor gene family in the kidney

Hayashi, M., Monkawa, T. & Saruta, T., 2000 Jul, In : Experimental Nephrology. 8, 4-5, p. 215-218 4 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Kidney
Protein Isoforms
Genes
Knockout Mice
13 Citations (Scopus)

Daily regeneration of rat adrenocortical cells: Circadian and zonal variations in cytogenesis

Miyamoto, H., Mitani, F., Mukai, K., Suematsu, M. & Ishimura, Y., 2000, In : Endocrine Research. 26, 4, p. 899-904 6 p.

Research output: Contribution to journalArticle

Regeneration
Adrenocorticotropic Hormone
Zona Fasciculata
Zona Glomerulosa
Adrenal Cortex
92 Citations (Scopus)

Identification of 25-hydroxyvitamin D3 1α-hydroxylase gene expression in macrophages

Monkawa, T., Yoshida, T., Hayashi, M. & Saruta, T., 2000, In : Kidney International. 58, 2, p. 559-568 10 p.

Research output: Contribution to journalArticle

Calcifediol
Mixed Function Oxygenases
Macrophages
Gene Expression
Messenger RNA
116 Citations (Scopus)

Interstitial lung disease in polymyositis and dermatomyositis

Hirakata, M. & Nagai, S., 2000, In : Current Opinion in Rheumatology. 12, 6, p. 501-508 8 p.

Research output: Contribution to journalArticle

Dermatomyositis
Interstitial Lung Diseases
Autoantibodies
Morbidity
Therapeutics
5 Citations (Scopus)

In vivo identification of parasinus macrophage in the mesenteric lymph node

Nagata, H., Hokari, R., Suzuki, H., Miura, S., Sekizuka, E. & Ishii, H., 2000, In : Clinical Hemorheology and Microcirculation. 23, 2-4, p. 345-348 4 p.

Research output: Contribution to journalArticle

Phagocytes
Lymph Nodes
Macrophages
Injections
Lymphatic Vessels
23 Citations (Scopus)

Matrix metalloproteinase expression in cultured human gastric wall fibroblasts - Interactions with Helicobacter pylori isolated from patients with ulcers

Yokoyama, T., Otani, Y., Kurihara, N., Sakurai, Y., Kameyama, K., Suzuki, H., Igarashi, N., Kimata, M., Wada, N., Kubota, T., Kumai, K. & Kitajima, M., 2000, In : Alimentary Pharmacology and Therapeutics, Supplement. 14, 1, p. 193-198 6 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Helicobacter pylori
Ulcer
Matrix Metalloproteinase 1
Stomach

Meningitis in mixed connective tissue disease

Mimori, T., Yasuoka, H., Suzuki, M., Nojima, T., Sato, S., Fujii, T., Suwa, A. & Hirakata, M., 2000, In : Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology. 23, 6, p. 647-651 5 p.

Research output: Contribution to journalArticle

Mixed Connective Tissue Disease
Meningitis
Systemic Lupus Erythematosus
16 Citations (Scopus)

Myositis and interstitial lung disease associated with autoantibody to a transfer RNA-related protein Wa

Kajihara, M., Kuwana, M., Tokuda, H., Yamane, K., Kubo, M., Hirakata, M. & Mimori, T., 2000, In : Journal of Rheumatology. 27, 11, p. 2707-2710 4 p.

Research output: Contribution to journalArticle

Myositis
Interstitial Lung Diseases
Transfer RNA
Autoantibodies
Systemic Scleroderma
61 Citations (Scopus)

Novel mutations in thiazide-sensitive Na-Cl cotransporter gene of patients with Gitelman's syndrome

Monkawa, T., Kurihara, I., Kobayashi, K., Hayashi, M. & Saruta, T., 2000 Jan, In : Journal of the American Society of Nephrology. 11, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

Gitelman Syndrome
Mutation
Genes
Missense Mutation
Alleles
28 Citations (Scopus)

Role of apoptosis in Helicobacter pylori-associated gastric mucosal injury

Suzuki, H. & Ishii, H., 2000, In : Journal of Gastroenterology and Hepatology (Australia). 15, SUPPL.

Research output: Contribution to journalArticle

Helicobacter pylori
Stomach
Apoptosis
Wounds and Injuries
Cell Death
3 Citations (Scopus)

Systemic lupus erythematosus associated with Down syndrome [4]

Suwa, A., Ezaki, T., Hirakata, M., Mimori, T., Satoh, S. & Inada, S., 2000, In : Clinical and Experimental Rheumatology. 18, 5, p. 650-651 2 p.

Research output: Contribution to journalArticle

Down Syndrome
Systemic Lupus Erythematosus
1999
8 Citations (Scopus)

A case of polymyositis with anti-OJ (isoleucyltransfer RNA synthetase) antibodies [5]

Suwa, A., Hirakata, M., Satoh, S., Ezaki, T., Mimori, T. & Inada, S., 1999, In : Clinical and Experimental Rheumatology. 17, 6, p. 755-756 2 p.

Research output: Contribution to journalArticle

Isoleucine-tRNA Ligase
Polymyositis
Ligases
Prednisolone
Autoantibodies

Anti-Jo-1 autoantibodies (anti-histidyl tRNA synthetase autoantibodies)

Hirakata, M. & Mimori, T., 1999, In : Nippon rinsho. Japanese journal of clinical medicine. 57 Suppl, p. 431-434 4 p.

Research output: Contribution to journalArticle

Histidine-tRNA Ligase
Precipitin Tests
Polymyositis
Dermatomyositis
Immunodiffusion
138 Citations (Scopus)

Anti-KS: Identification of autoantibodies to asparaginyl-transfer RNA synthetase associated with interstitial lung disease

Hirakata, M., Suwa, A., Nagai, S., Kron, M. A., Trieu, E. P., Mimori, T., Akizuki, M. & Targoff, I. N., 1999 Feb 15, In : Journal of Immunology. 162, 4, p. 2315-2320 6 p.

Research output: Contribution to journalArticle

Amino Acyl-tRNA Synthetases
Interstitial Lung Diseases
asparaginyl-tRNA synthetase
Myositis
Autoantibodies
Histidine-tRNA Ligase
Amino Acyl-tRNA Synthetases
Polymyositis
Dermatomyositis
Autoantibodies
50 Citations (Scopus)

Association of human leukocyte antigen class II genes with autoantibody profiles, but not with disease susceptibility in Japanese patients with systemic sclerosis

Kuwana, M., Inoko, H., Kameda, H., Nojima, T., Sato, S., Nakamura, K., Ogasawara, T., Hirakata, M., Ohosone, Y., Kaburaki, J., Okano, Y. & Mimori, T., 1999 Apr, In : Internal Medicine. 38, 4, p. 336-344 9 p.

Research output: Contribution to journalArticle

MHC Class II Genes
Systemic Scleroderma
Disease Susceptibility
HLA Antigens
Autoantibodies
28 Citations (Scopus)

Calcitonin induces 25-hydroxyvitamin D3 1α-hydroxylase mRNA expression via protein kinase C pathway in LLC-PK1 cells

Yoshida, N., Yoshida, T., Nakamura, A., Monkawa, T., Hayashi, M. & Saruta, T., 1999 Dec, In : Journal of the American Society of Nephrology. 10, 12, p. 2474-2479 6 p.

Research output: Contribution to journalArticle

25-Hydroxyvitamin D3 1-alpha-Hydroxylase
LLC-PK1 Cells
Calcifediol
Calcitonin
Mixed Function Oxygenases
31 Citations (Scopus)

Carbon monoxide-mediated alterations in paracellular permeability and vesicular transport in acetaminophen-treated perfused rat liver

Mori, M., Suematsu, M., Kyokane, T., Sano, T., Suzuki, H., Yamaguchi, T., Ishimura, Y. & Ishii, H., 1999, In : Hepatology. 30, 1, p. 160-168 9 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Acetaminophen
Heme Oxygenase (Decyclizing)
Permeability
Liver
20 Citations (Scopus)

Cloning of porcine 25-hydroxyvitamin D3 1α-hydroxylase and its regulation by cAMP in LLC-PK1 cells

Yoshida, T., Yoshida, N., Nakamura, A., Monkawa, T., Hayashi, M. & Saruta, T., 1999 May, In : Journal of the American Society of Nephrology. 10, 5, p. 963-970 8 p.

Research output: Contribution to journalArticle

25-Hydroxyvitamin D3 1-alpha-Hydroxylase
LLC-PK1 Cells
Calcifediol
Mixed Function Oxygenases
Organism Cloning
70 Citations (Scopus)

Development of functional zonation in the rat adrenal cortex

Mitani, F., Mukai, K., Miyamoto, H., Suematsu, M. & Ishimura, Y., 1999, In : Endocrinology. 140, 7, p. 3342-3353 12 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Zona Fasciculata
Zona Glomerulosa
DNA
Zona Reticularis
17 Citations (Scopus)

Enhanced DNA fragmentation in the thymus of spontaneously hypertensive rats

Suzuki, H., Delano, F. A., Jamshidi, N., Katz, D., Mori, M., Kosaki, K., Gottlieb, R. A., Ishii, H. & Schmid-Schönbein, G. W., 1999 Jun, In : American Journal of Physiology - Heart and Circulatory Physiology. 276, 6 45-6

Research output: Contribution to journalArticle

DNA Fragmentation
Inbred SHR Rats
Thymus Gland
Inbred WKY Rats
Adrenalectomy
8 Citations (Scopus)

Ethanol intake preceding Helicobacter pylori inoculation promotes gastric mucosal inflammation in Mongolian gerbils

Suzuki, H., Mori, M., Seto, K., Nagahashi, S., Kawaguchi, C., Kai, A., Akiba, Y., Suzuki, M., Suematsu, M., Miura, S. & Ishii, H., 1999, In : Journal of Gastroenterology and Hepatology (Australia). 14, 11, p. 1062-1069 8 p.

Research output: Contribution to journalArticle

Gerbillinae
Helicobacter pylori
Stomach
Ethanol
Inflammation
54 Citations (Scopus)

Helicobacter pylori-associated gastric pro- and antioxidant formation in mongolian gerbils

Suzuki, H., Mori, M., Seto, K., Kai, A., Kawaguchi, C., Suzuki, M., Suematsu, M., Yoneta, T., Miura, S. & Ishii, H., 1999 Mar, In : Free Radical Biology and Medicine. 26, 5-6, p. 679-684 6 p.

Research output: Contribution to journalArticle

Gerbillinae
Helicobacter pylori
Glutathione
Stomach
Thiobarbituric Acid Reactive Substances
43 Citations (Scopus)

Increased expression of inducible nitric oxide synthase and peroxynitrite in Helicobacter Pylori gastric ulcer

Sakaguchi, A. A., Miura, S., Takeuchi, T., Hokari, R., Mizumori, M., Yoshida, H., Higuchi, H., Mori, M., Kimura, H., Suzuki, H. & Ishii, H., 1999 Oct, In : Free Radical Biology and Medicine. 27, 7-8, p. 781-789 9 p.

Research output: Contribution to journalArticle

Peroxynitrous Acid
Nitric Oxide Synthase Type II
Stomach Ulcer
Helicobacter pylori
Ulcer
10 Citations (Scopus)

Intracellular calcium concentration in the inositol trisphosphate receptor type 1 knockout mouse

Hayashi, M., Monkawa, T., Yoshida, T., Sasamura, H., Matsumoto, M., Inoue, T., Mikoshiba, K. & Saruta, T., 1999 Oct, In : Journal of the American Society of Nephrology. 10, 10, p. 2094-2101 8 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Inositol
Knockout Mice
Calcium
Angiotensin II
3 Citations (Scopus)

Microvascular oxidative stress, immune reaction and apoptosis in hypertensives

Suzuki, H., Suematsu, M. & Schmid-Schönbein, G. W., 1999, In : Clinical Hemorheology and Microcirculation. 21, 3-4, p. 161-168 8 p.

Research output: Contribution to journalArticle

Glucocorticoids
Endothelium
Oxidative Stress
Apoptosis
Hypertension
28 Citations (Scopus)

Omeprazole attenuates neutrophil-endothelial cell adhesive interaction induced by extracts of Helicobacter pylori

Suzuki, M., Mori, M., Fukumura, D., Suzuki, H., Miura, S. & Ishii, H., 1999, In : Journal of Gastroenterology and Hepatology (Australia). 14, 1, p. 27-31 5 p.

Research output: Contribution to journalArticle

Omeprazole
Helicobacter pylori
Cell Communication
Adhesives
Neutrophils
21 Citations (Scopus)

Paracrine upregulation of VEGF receptor mRNA in endothelial cells by hypoxia-exposed Hep G2 cells

Suzuki, H., Seto, K., Shinoda, Y., Mori, M., Ishimura, Y., Suematsu, M. & Ishii, H., 1999 Jan, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 276, 1 39-1

Research output: Contribution to journalArticle

Cell Hypoxia
Vascular Endothelial Growth Factor Receptor
Hep G2 Cells
Vascular Endothelial Growth Factor A
Up-Regulation
15 Citations (Scopus)

Polaprezinc, a gastroprotective agent: Attenuation of monochloramine-evoked gastric DNA fragmentation

Suzuki, H., Mori, M., Seto, K., Nagahashi, S., Kawaguchi, C., Morita, H., Suzuki, M., Miura, S., Yoneta, T. & Ishii, H., 1999 Dec, In : Journal of Gastroenterology. 34, SUPPL. 11, p. 43-46 4 p.

Research output: Contribution to journalArticle

polaprezinc
Carnosine
DNA Fragmentation
Stomach
Carotenoids
10 Citations (Scopus)

Protective role of adrenal glucocorticoids for gastric mucosa in spontaneously hypertensive rats

Suzuki, H., Miura, S., Mori, M., Akiba, Y., Nagahashi, S., Zweifach, B. W., Ishii, H. & Schmid-Schönbein, G. W., 1999, In : Journal of Gastroenterology and Hepatology (Australia). 14, 4, p. 376-383 8 p.

Research output: Contribution to journalArticle

Inbred SHR Rats
Gastric Mucosa
Glucocorticoids
Inbred WKY Rats
Adrenalectomy
30 Citations (Scopus)

Rheumatoid arthritis associated with methotrexate-induced pneumonitis: Improvement with i.v. cyclophosphamide therapy

Suwa, A., Hirakata, M., Satoh, S., Mimori, T., Utsumi, K. & Inada, S., 1999, In : Clinical and Experimental Rheumatology. 17, 3, p. 355-358 4 p.

Research output: Contribution to journalArticle

Methotrexate
Cyclophosphamide
Rheumatoid Arthritis
Pneumonia
Therapeutics
50 Citations (Scopus)

Serum vascular endothelial growth factor in the course of transcatheter arterial embolization of Hepatocellular Carcinoma

Suzuki, H., Mori, M., Kawaguchi, C., Adachi, M., Miura, S. & Ishii, H., 1999 Jun, In : International Journal of Oncology. 14, 6, p. 1087-1090 4 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Hepatocellular Carcinoma
Liver
Hepatocyte Growth Factor
Serum
1 Citation (Scopus)

Simultaneous analysis of propionic acid analgesic and antipyretic drugs in human plasma by gas chromatography

Shinozuka, T., Nakajima, R., Takei, S., Ohue, O., Ogamo, A., Terada, M., Murai, T. & Yanagida, J., 1999, In : Japanese Journal of Forensic Toxicology. 17, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Plasma Gases
Antipyretics
Gas chromatography
Gas Chromatography
Analgesics
27 Citations (Scopus)

Studies on cytogenesis in adult rat adrenal cortex: Circadian and zonal variations and their modulation by adrenocorticotropic hormone

Miyamoto, H., Mitani, F., Mukai, K., Suematsu, M. & Ishimura, Y., 1999, In : Journal of Biochemistry. 126, 6, p. 1175-1183 9 p.

Research output: Contribution to journalArticle

Adrenal Cortex
Adrenocorticotropic Hormone
Cell proliferation
Rats
Zona Fasciculata
1998
5 Citations (Scopus)

A case of systemic lupus erythematosus associated with spinal epidural hematoma

Satoh, S., Hirakata, M., Kameda, H., Hama, N., Yoshida, T., Mimori, T., Akizuki, M. & Ikeda, Y., 1998, In : Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology. 21, 4, p. 166-171 6 p.

Research output: Contribution to journalArticle

Spinal Epidural Hematoma
Systemic Lupus Erythematosus
Spinal Cord Diseases
Thoracic Vertebrae
Hematoma
6 Citations (Scopus)

Acute exacerbation of subacute interstitial pneumonia after thoracoscopic lung biopsy

Tasaka, S., Kanazawa, M., Komune, Y., Soejima, K., Hirakata, M., Yamaguchi, K., Naruke, M., Mukai, M., Kawabata, Y. & Kobayashi, K., 1998, In : Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 36, 2, p. 182-186 5 p.

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Lymphocytes
Biopsy
Lung
Steroids
32 Citations (Scopus)

Adrenocorticotropic hormone stimulates CYP11B1 gene transcription through a mechanism involving AP-1 factors

Mukai, K., Mitani, F., Agake, R. & Ishimura, Y., 1998 Aug 15, In : European Journal of Biochemistry. 256, 1, p. 190-200 11 p.

Research output: Contribution to journalArticle

Steroid 11-beta-Hydroxylase
Transcription Factor AP-1
Transcription
Adrenocorticotropic Hormone
Genes
2 Citations (Scopus)

Analysis of autoantigens and clinical significance of antinuclear antibodies

Mimori, T., Matsumura, M., Ishida, M., Takahashi, Y., Hirakata, M. & Ohosone, Y., 1998, In : Rinsho byori. The Japanese journal of clinical pathology. 46, 4, p. 303-310 8 p.

Research output: Contribution to journalArticle

Antinuclear Antibodies
Autoantigens
Transfer RNA
Autoantibodies
Serum
9 Citations (Scopus)

A novel antibody directed against a three-dimensional configuration of a 95-kDa protein in patients with autoimmune hepatic diseases

Miyachi, K., Matsushima, H., Hankins, R. W., Hirakata, M., Mimori, T., Hosaka, H., Amagasaki, Y., Miyakawa, H., Kako, M., Shibata, M., Onozuka, Y. & Ueno, U., 1998, In : Scandinavian Journal of Immunology. 47, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Antibodies
Liver
Serum
Cell Extracts
25 Citations (Scopus)

Augmented levels of gastric mucosal leucocyte activation by infection with cagA gene-positive Helicobacter pylori

Suzuki, H., Suzuki, M., Mori, M., Kitahora, T., Yokoyama, H., Miura, S., Hibi, T. & Ishii, H., 1998, In : Journal of Gastroenterology and Hepatology (Australia). 13, 3, p. 294-300 7 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Stomach
Leukocytes
Infection
Reactive Oxygen Species
2 Citations (Scopus)
Rheumatic Diseases
Cell Extracts
HeLa Cells
Immunoblotting
Autoantibodies
15 Citations (Scopus)

Effect of chronic ethanol feeding on endotoxininduced hepatic injury: Role of adhesion molecules on leukocytes and hepatic sinusoid

Ohki, E., Kato, S., Ohgo, H., Mizukami, T., Fukuda, M., Tamai, H., Okamura, Y., Matsumoto, M., Suzuki, H., Yokoyama, H. & Ishii, H., 1998, In : Alcoholism: Clinical and Experimental Research. 22, 3 SUPPL. 1

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Rats
Ethanol
Liver
Adhesion