Center for Preventive Medicine

Research Output

2020

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Mizuno, S., Ono, K., Mikami, Y., Naganuma, M., Fukuda, T., Minami, K., Masaoka, T., Terada, S., Yoshida, T., Saigusa, K., Hirahara, N., Miyata, H., Suda, W., Hattori, M. & Kanai, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A Case of Rare Cutaneous Metastasis from Advanced Pancreatic Cancer

Ito, H., Tajiri, T., Hiraiwa, S. I., Sugiyama, T., Ito, A., Shinma, Y., Kaneko, M., Anzai, K., Tsuda, S., Ichikawa, H., Nagata, J., Kojima, S. & Watanabe, N., 2020, In : Case Reports in Oncology. 13, 1, p. 49-54 6 p.

Research output: Contribution to journalArticle

Open Access

Adherence to antihypertensive medication and its predictors among non-elderly adults in Japan

Nishimura, S., Kumamaru, H., Shoji, S., Sawano, M., Kohsaka, S. & Miyata, H., 2020 Jul 1, In : Hypertension Research. 43, 7, p. 705-714 10 p.

Research output: Contribution to journalArticle

A Phase II Study of Regorafenib With a Lower Starting Dose in Patients With Metastatic Colorectal Cancer: Exposure–Toxicity Analysis of Unbound Regorafenib and Its Active Metabolites (RESET Trial)

Suzuki, T., Sukawa, Y., Imamura, C., Masuishi, T., Satake, H., Kumekawa, Y., Funakoshi, S., Kotaka, M., Horie, Y., Kawai, S., Okuda, H., Terazawa, T., Kondoh, C., Kato, K., Yoshimura, K., Ishikawa, H., Hamamoto, Y., Boku, N., Takaishi, H. & Kanai, T., 2020 Mar, In : Clinical Colorectal Cancer. 19, 1, p. 13-21.e3

Research output: Contribution to journalArticle

A significant association of non-obese non-alcoholic fatty liver disease with sarcopenic obesity

Kashiwagi, K., Takayama, M., Fukuhara, K., Shimizu-Hirota, R., Chu, P. S., Nakamoto, N., Inoue, N., Iwao, Y. & Kanai, T., 2020 Aug, In : Clinical Nutrition ESPEN. 38, p. 86-93 8 p.

Research output: Contribution to journalArticle

Open Access

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: The Hisayama Study

Inaishi, J., Saisho, Y., Hirakawa, Y., Yoshida, D., Hata, J., Mukai, N., Watanabe, Y., Oda, Y., Itoh, H. & Ninomiya, T., 2020 Jan 1, (Accepted/In press) In : Journal of Diabetes Investigation.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Associations of birthweight and history of childhood obesity with beta cell mass in Japanese adults

Sasaki, H., Saisho, Y., Inaishi, J., Watanabe, Y., Tsuchiya, T., Makio, M., Sato, M., Kitago, M., Yamada, T. & Itoh, H., 2020 Jun 1, In : Diabetologia. 63, 6, p. 1199-1210 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Case of isolated neurosarcoidosis requiring differentiation from tuberculous meningitis

Deguchi, I., Osada, T., Suzuki, T., Tabata, S., Arai, E., Uchino, A., Hayashi, T., Takahashi, S., Momoshima, S. & Takao, M., 2020, In : Clinical Neurology. 60, 3, p. 213-218 6 p.

Research output: Contribution to journalArticle

Open Access

Clinical, Endoscopic, and Pathological Characteristics of Immune Checkpoint Inhibitor-Induced Gastroenterocolitis

Hayashi, Y., Hosoe, N., Takabayashi, K., Limpias Kamiya, K. J. L., Tsugaru, K., Shimozaki, K., Hirata, K., Fukuhara, K., Fukuhara, S., Mutaguchi, M., Sujino, T., Sukawa, Y., Hamamoto, Y., Naganuma, M., Takaishi, H., Shimoda, M., Ogata, H. & Kanai, T., 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Clinical characteristics of patients with not well-controlled severe asthma in Japan: Analysis of the Keio Severe Asthma Research Program in Japanese population (KEIO-SARP) registry

Tanosaki, T., Kabata, H., Matsusaka, M., Miyata, J., Masaki, K., Mochimaru, T., Okuzumi, S., Kuwae, M., Watanabe, R., Suzuki, Y., Sayama, K., Izuhara, K., Asano, K. & Fukunaga, K., 2020, (Accepted/In press) In : Allergology International.

Research output: Contribution to journalArticle

Open Access

Development of an Indigo Naturalis Suppository for Topical Induction Therapy in Patients with Ulcerative Colitis

Yoshimatsu, Y., Naganuma, M., Sugimoto, S., Tanemoto, S., Umeda, S., Fukuda, T., Nomura, E., Yoshida, K., Ono, K., Mutaguchi, M., Nanki, K., Mizuno, S., Mikami, Y., Fukuhara, K., Sujino, T., Takabayashi, K., Ogata, H., Iwao, Y. & Kanai, T., 2020 Jul 1, In : Digestion. 101, 4, p. 492-498 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Discrepancy in recognition of symptom burden among patients with atrial fibrillation

Katsumata, Y., Kimura, T., Kohsaka, S., Ikemura, N., Ueda, I., Fujisawa, T., Nakajima, K., Nishiyama, T., Aizawa, Y., Oki, T., Suzuki, M., Heidenreich, P. A., Fukuda, K. & Takatsuki, S., 2020, (Accepted/In press) In : American heart journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Efficacy and safety of immediate oral intake in patients with mild acute pancreatitis: A randomized controlled trial

Horibe, M., Iwasaki, E., Nakagawa, A., Matsuzaki, J., Minami, K., Machida, Y., Tamagawa, H., Takimoto, Y., Ueda, M., Katayama, T., Kawasaki, S., Matsushita, M., Seino, T., Fukuhara, S. & Kanai, T., 2020 Jun, In : Nutrition. 74, 110724.

Research output: Contribution to journalArticle

Efficacy and safety of once-weekly exenatide after switching from twice-daily exenatide in patients with type 2 diabetes

for the Twin-exenatide Study Group, 2020 Mar 1, In : Journal of Diabetes Investigation. 11, 2, p. 382-388 7 p.

Research output: Contribution to journalArticle

Open Access

Evidence-based diagnosis and clinical practice guidelines for intestinal Behçet’s disease 2020 edited by Intractable Diseases, the Health and Labour Sciences Research Grants

Watanabe, K., Tanida, S., Inoue, N., Kunisaki, R., Kobayashi, K., Nagahori, M., Arai, K., Uchino, M., Koganei, K., Kobayashi, T., Takeno, M., Ueno, F., Matsumoto, T., Mizuki, N., Suzuki, Y. & Hisamatsu, T., 2020 Jul 1, In : Journal of gastroenterology. 55, 7, p. 679-700 22 p.

Research output: Contribution to journalArticle

Open Access

FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression

Kodani, N., Nakae, J., Kobayashi, M., Kikuchi, O., Kitamura, T. & Itoh, H., 2020 Jan 24, In : iScience. 23, 1, 100798.

Research output: Contribution to journalArticle

Open Access

Horibe GI bleeding prediction score: a simple score for triage decision-making in patients with suspected upper GI bleeding

Horibe, M., Iwasaki, E., Bazerbachi, F., Kaneko, T., Matsuzaki, J., Minami, K., Masaoka, T., Hosoe, N., Ogura, Y., Namiki, S., Hosoda, Y., Ogata, H., Chan, A. T. & Kanai, T., 2020, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Hospital meal intake in acute heart failure patients and its association with long-term outcomes

Yoshida, T., Shoji, S., Shiraishi, Y., Kawana, M., Kohno, T., Inoue, K., Fukuda, K., Heidenreich, P. A. & Kohsaka, S., 2020 May 10, In : Open Heart. 7, 1, e001248.

Research output: Contribution to journalArticle

Open Access

Impact of electrical pulse cut mode during endoscopic papillectomy: Pilot randomized clinical trial

Iwasaki, E., Minami, K., Itoi, T., Yamamoto, K., Tsuji, S., Sofuni, A., Tsuchiya, T., Tanaka, R., Tonozuka, R., Machida, Y., Takimoto, Y., Tamagawa, H., Katayama, T., Kawasaki, S., Seino, T., Horibe, M., Fukuhara, S., Kitago, M., Ogata, H. & Kanai, T., 2020 Jan 1, In : Digestive Endoscopy. 32, 1, p. 127-135 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Improving obesity and blood pressure

Tanaka, M., 2020 Feb 1, In : Hypertension Research. 43, 2, p. 79-89 11 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study

For the INDIGO Study Group, 2020 Feb 1, In : Journal of gastroenterology. 55, 2, p. 169-180 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice

Imai, J., Yahata, T., Ichikawa, H., Ibrahim, A. A., Yazawa, M., Sumiyoshi, H., Inagaki, Y., Matsushima, M., Suzuki, T., Mine, T., Ando, K., Miyata, T. & Hozumi, K., 2020, In : Intestinal Research. 18, 2, p. 219-228 10 p., 0037.

Research output: Contribution to journalArticle

Open Access

Ischemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment

Shoji, S., Sawano, M., Sandhu, A. T., Heidenreich, P. A., Shiraishi, Y., Ikemura, N., Ueno, K., Suzuki, M., Numasawa, Y., Fukuda, K. & Kohsaka, S., 2020 Apr 1, In : JAMA network open. 3, 4, p. e202004

Research output: Contribution to journalArticle

Open Access

Levonorgestrel Inhibits Embryo Attachment by Eliminating Uterine Induction of Leukemia Inhibitory Factor

Matsuo, M., Hirota, Y., Fukui, Y., Fujita, H., Saito-Fujita, T., Kaku, T., Gebril, M., Hirata, T., Akaeda, S., Hiraoka, T., Tanaka, T., Haraguchi, H., Saito-Kanatani, M., Shimizu-Hirota, R., Takeda, N., Fujii, T. & Osuga, Y., 2020 Feb 1, In : Endocrinology (United States). 161, 2, bqz005.

Research output: Contribution to journalArticle

Long-Term Outcomes According to Etiology May Alter Under Different Circumstances

Shoji, S., Shiraishi, Y., Kohsaka, S., Fukuda, K. & Yoshikawa, T., 2020 Jan, In : JACC: Heart Failure. 8, 1, p. 83-84 2 p.

Research output: Contribution to journalLetter

Open Access

Management of perforation related to endoscopic submucosal dissection for superficial duodenal epithelial tumors

Fukuhara, S., Kato, M., Iwasaki, E., Sasaki, M., Tsutsumi, K., Kiguchi, Y., Akimoto, T., Takatori, Y., Nakayama, A., Maehata, T., Minami, K., Ogata, H., Kanai, T. & Yahagi, N., 2020 May, In : Gastrointestinal Endoscopy. 91, 5, p. 1129-1137 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine

Fukuda, T., Naganuma, M., Takabayashi, K., Hagihara, Y., Tanemoto, S., Nomura, E., Yoshimatsu, Y., Sugimoto, S., Nanki, K., Mizuno, S., Mikami, Y., Fukuhara, K., Sujino, T., Mutaguchi, M., Inoue, N., Ogata, H., Iwao, Y., Abe, T. & Kanai, T., 2020, (Accepted/In press) In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalArticle

Open Access

Multiple immune-related adverse events and anti-tumor efficacy: Real-world data on various solid tumors

Shimozaki, K., Sukawa, Y., Beppu, N., Kurihara, I., Suzuki, S., Mizuno, R., Funakoshi, T., Ikemura, S., Tsugaru, K., Togasaki, K., Kawasaki, K., Hirata, K., Hayashi, H., Hamamoto, Y., Takaishi, H. & Kanai, T., 2020, In : Cancer Management and Research. 12, p. 4585-4593 9 p.

Research output: Contribution to journalArticle

Open Access

Potential association of metabolic and musculoskeletal disorders with lumbar intervertebral disc degeneration: Cross-sectional study using medical checkup data

Fujita, N., Ishihara, S., Michikawa, T., Azuma, K., Suzuki, S., Tsuji, O., Nagoshi, N., Okada, E., Yagi, M., Tsuji, T., Takayama, M., Matsumoto, H., Nakamura, M., Matsumoto, M. & Watanabe, K., 2020 May, In : Journal of Orthopaedic Science. 25, 3, p. 384-388 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Predictors of residual low back pain after acute osteoporotic compression fracture

Inose, H., Kato, T., Ichimura, S., Nakamura, H., Hoshino, M., Togawa, D., Hirano, T., Tokuhashi, Y., Ohba, T., Haro, H., Tsuji, T., Sato, K., Sasao, Y., Takahata, M., Otani, K., Momoshima, S., Yuasa, M., Hirai, T., Yoshii, T. & Okawa, A., 2020, (Accepted/In press) In : Journal of Orthopaedic Science.

Research output: Contribution to journalArticle

Risk Factors of Nonunion After Acute Osteoporotic Vertebral Fractures: A Prospective Multicenter Cohort Study

Inose, H., Kato, T., Ichimura, S., Nakamura, H., Hoshino, M., Togawa, D., Hirano, T., Tokuhashi, Y., Ohba, T., Haro, H., Tsuji, T., Sato, K., Sasao, Y., Takahata, M., Otani, K., Momoshima, S., Yuasa, M., Hirai, T., Yoshii, T. & Okawa, A., 2020 Jul 1, In : Spine. 45, 13, p. 895-902 8 p.

Research output: Contribution to journalArticle

Open Access

Significance of echocardiographic evaluation for transcatheter aortic valve implantation

Shirakawa, K. & Murata, M., 2020 Jan 1, In : Cardiovascular Intervention and Therapeutics. 35, 1, p. 85-95 11 p.

Research output: Contribution to journalReview article

Open Access

Successful Retreatment Using Pembrolizumab for Non–small-cell Lung Cancer After Severe Immune-related Hepatitis: A Case Report

Kobayashi, K., Nakachi, I., Mitsuishi, A., Arai, D., Sakurai, K., Masaki, K., Chiyotani, A., Takahashi, H., Tahara, T. & Soejima, K., 2020 Jan, In : Clinical Lung Cancer. 21, 1, p. e30-e32

Research output: Contribution to journalArticle

Toward the realization of cardiac regenerative medicine using pluripotent stem cells

Kishino, Y., Fujita, J., Tohyama, S., Okada, M., Tanosaki, S., Someya, S. & Fukuda, K., 2020 Jan 13, In : Inflammation and Regeneration. 40, 1, 1.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Transient hypotension during endoscopic resection of gangliocytic paraganglioma with ampullary involvement

Katayama, T., Iwasaki, E., Minami, K., Fukuhara, S. & Kanai, T., 2020 Jan, In : VideoGIE. 5, 1, p. 26-28 3 p.

Research output: Contribution to journalArticle

Open Access
2019

A multimodal (FACILE) classification for optical diagnosis of inflammatory bowel disease associated neoplasia

Iacucci, M., McQuaid, K., Gui, X. S., Iwao, Y., Lethebe, B. C., Lowerison, M., Matsumoto, T., Shivaji, U. N., Smith, S. C. L., Subramanian, V., Uraoka, T., Sanduleanu, S., Ghosh, S. & Kiesslich, R., 2019, In : Endoscopy. 51, 2, p. 133-141 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

An Autopsy Case of Anaplastic Pancreatic Ductal Carcinoma (Spindle Cell Type) Multiple Onset in the Pancreas

Ito, H., Hiraiwa, S. I., Sugiyama, T., Tajiri, T., Yoshii, H., Izumi, H., Yamaji, Y., Kaneko, M., Tsuda, S., Ichikawa, H., Nagata, J., Kojima, S., Takashimizu, S., Shirai, T. & Watanabe, N., 2019 Jan 1, In : Case Reports in Oncology. 12, 1, p. 332-338 7 p.

Research output: Contribution to journalArticle

Open Access

An autopsy case of primary extranodal NK/T cell lymphoma (extranodal NK/T-cell lymphoma) of the bile duct

Ito, H., Hiraiwa, S. I., Sugiyama, T., Tajiri, T., Yamaji, Y., Kaneko, M., Tsuda, S., Ichikawa, H., Nagata, J., Kojima, S., Takashimizu, S., Shirai, T. & Watanabe, N., 2019 Jun 1, In : Clinical journal of gastroenterology. 12, 3, p. 209-212 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Association between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study

Inaishi, J., Hirakawa, Y., Horikoshi, M., Akiyama, M., Higashioka, M., Yoshinari, M., Hata, J., Mukai, N., Kamatani, Y., Momozawa, Y., Kubo, M. & Ninomiya, T., 2019 Jun 19, In : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3213-3222 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cancer therapeutics-related cardiac dysfunction in a patient treated with abiraterone for castration-resistant prostate cancer

Tsugu, T., Nagatomo, Y., Nakajima, Y., Kageyama, T., Akise, Y., Endo, J., Itabashi, Y., Murata, M. & Mitamura, H., 2019 Apr 15, In : Journal of Medical Ultrasonics. 46, 2, p. 239-243 5 p.

Research output: Contribution to journalArticle

Clinical and endoscopic findings to assist the early detection of duodenal adenoma and adenocarcinoma

Matsuzaki, J., Suzuki, H., Shimoda, M., Mori, H., Fukuhara, S., Miyoshi, S., Masaoka, T., Iwao, Y., Kanai, Y. & Kanai, T., 2019 Mar 1, In : United European Gastroenterology Journal. 7, 2, p. 250-260 11 p.

Research output: Contribution to journalArticle

Clinicopathological features of clinical methotrexate-related lymphoproliferative disorders

Tokuhira, M., Saito, S., Suzuki, K., Higashi, M., Momose, S., Shimizu, T., Mori, T., Kimura, Y., Amano, K., Okamoto, S., Takeuchi, T., Tamaru, J. I. & Kizaki, M., 2019 Aug 24, In : Leukemia and Lymphoma. 60, 10, p. 2508-2515 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Concise Review: Genetic and Epigenetic Regulation of Cardiac Differentiation from Human Pluripotent Stem Cells

Fujita, J., Tohyama, S., Kishino, Y., Okada, M. & Morita, Y., 2019 Aug, In : Stem Cells. 37, 8, p. 992-1002 11 p.

Research output: Contribution to journalReview article

Open Access
5 Citations (Scopus)

Delayed hemopericardium due to non-penetrating chest trauma: a report of new case and literature review

Tsugu, T., Nagatomo, Y., Tanigawa, T., Endo, J., Itabashi, Y., Murata, M. & Mitamura, H., 2019 Jan 25, In : Journal of Medical Ultrasonics. 46, 1, p. 159-162 4 p.

Research output: Contribution to journalArticle

Development of a transplant injection device for optimal distribution and retention of human induced pluripotent stem cell‒derived cardiomyocytes

Tabei, R., Kawaguchi, S., Kanazawa, H., Tohyama, S., Hirano, A., Handa, N., Hishikawa, S., Teratani, T., Kunita, S., Fukuda, J., Mugishima, Y., Suzuki, T., Nakajima, K., Seki, T., Kishino, Y., Okada, M., Yamazaki, M., Okamoto, K., Shimizu, H., Kobayashi, E. & 3 others, Tabata, Y., Fujita, J. & Fukuda, K., 2019 Feb, In : Journal of Heart and Lung Transplantation. 38, 2, p. 203-214 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure

Shoji, S., Shiraishi, Y., Sawano, M., Katsumata, Y., Yuasa, S., Kono, T., Fukuda, K., Spertus, J. A. & Kohsaka, S., 2019 Sep 13, In : Heart and vessels. 34, 9, p. 1464-1470 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)