Department of Biosciences and Informatics

Research Output 1987 2020

Filter
Article
2017
1 Citation (Scopus)

Liposomal internal viscosity affects the fate of membrane deformation induced by hypertonic treatment

Fujiwara, K. & Yanagisawa, M., 2017 Jan 1, In : Soft Matter. 13, 48, p. 9192-9198 7 p.

Research output: Contribution to journalArticle

Viscosity
viscosity
membranes
Membranes
Membrane Lipids
1 Citation (Scopus)

Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells

Ikeda, H., Shikata, Y., Watanapokasin, R., Tashiro, E. & Imoto, M., 2017 Jan 1, In : Journal of Antibiotics. 70, 1, p. 109-112 4 p.

Research output: Contribution to journalArticle

beta Catenin
Cell Death
Neoplasms
metacycloprodigiosin
6 Citations (Scopus)

Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells

Shikata, Y., Kiga, M., Futamura, Y., Aono, H., Inoue, H., Kawada, M., Osada, H. & Imoto, M., 2017 Apr 1, In : Cancer Science. 108, 4, p. 772-784 13 p.

Research output: Contribution to journalArticle

Catenins
Neoplasms
Apoptosis
Heterografts
Mutation
6 Citations (Scopus)

Muscle architectural properties in the common marmoset (Callithrix jacchus)

Ogihara, N., Oishi, M., Kanai, R., Shimada, H., Kondo, T., Yoshino-Saito, K., Ushiba, J. & Okano, H., 2017 May 8, (Accepted/In press) In : Primates. p. 1-12 12 p.

Research output: Contribution to journalArticle

Callithrix jacchus
muscles
forelimbs
limbs (animal)
Macaca fuscata
8 Citations (Scopus)

Nonthmicin, a Polyether Polyketide Bearing a Halogen-Modified Tetronate with Neuroprotective and Antiinvasive Activity from Actinomadura sp.

Igarashi, Y., Matsuoka, N., In, Y., Kataura, T., Tashiro, E., Saiki, I., Sudoh, Y., Duangmal, K. & Thamchaipenet, A., 2017 Mar 17, In : Organic Letters. 19, 6, p. 1406-1409 4 p.

Research output: Contribution to journalArticle

Bearings (structural)
Polyketides
Halogens
Polyethers
halogens
1 Citation (Scopus)

Protein kinase A activity leads to the extension of the acrosomal process in starfish sperm

Niikura, K., Alam, M. S., Naruse, M., Jimbo, M., Moriyama, H., Reich, A., Wessel, G. M. & Matsumoto, M., 2017, (Accepted/In press) In : Molecular Reproduction and Development.

Research output: Contribution to journalArticle

Starfish
Acrosome Reaction
Cyclic AMP-Dependent Protein Kinases
Spermatozoa
Exocytosis
3 Citations (Scopus)

Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor

Shikata, Y., Yoshimaru, T., Komatsu, M., Katoh, H., Sato, R., Kanagaki, S., Okazaki, Y., Toyokuni, S., Tashiro, E., Ishikawa, S., Katagiri, T. & Imoto, M., 2017 Apr 1, In : Cancer Science. 108, 4, p. 785-794 10 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Tumor Cell Line
Adenylyl Cyclases
Chalcone
Humulus
1 Citation (Scopus)

Protein Nanoparticle Formation Using a Circularly Permuted α-Helix-Rich Trimeric Protein

Kawakami, N., Kondo, H., Muramatsu, M. & Miyamoto, K., 2017 Feb 15, In : Bioconjugate Chemistry. 28, 2, p. 336-340 5 p.

Research output: Contribution to journalArticle

Nanoparticles
Proteins
Chaperonins
Oligomerization
Drug Carriers
2 Citations (Scopus)

Rapid identification of cortical motor areas in rodents by high-frequency automatic cortical stimulation and novel motor threshold algorithm

Takemi, M., Castagnola, E., Ansaldo, A., Ricci, D., Fadiga, L., Taoka, M., Iriki, A. & Ushiba, J., 2017 Oct 17, In : Frontiers in Neuroscience. 11, OCT, 580.

Research output: Contribution to journalArticle

Motor Cortex
Rodentia
Neurophysiology
Brain Neoplasms
Brain Injuries
7 Citations (Scopus)

Resting-state fluctuations of EEG sensorimotor rhythm reflect BOLD activities in the pericentral areas: A simultaneous EEG-fMRI study

Tsuchimoto, S., Shibusawa, S., Mizuguchi, N., Kato, K., Ebata, H., Liu, M., Hanakawa, T. & Ushiba, J., 2017 Jul 6, In : Frontiers in Human Neuroscience. 11, 356.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Oxygen
Beta Rhythm
Alpha Rhythm
Somatosensory Cortex
1 Citation (Scopus)

Saccharide Primers Comprising Xylosyl-Serine Primed Phosphorylated Oligosaccharides Act as Intermediates in Glycosaminoglycan Biosynthesis

Otsuka, Y. & Sato, T., 2017 Jul 31, In : ACS Omega. 2, 7, p. 3110-3122 13 p.

Research output: Contribution to journalArticle

Oligosaccharides
Biosynthesis
Glycosaminoglycans
Serine
Phosphorylation
9 Citations (Scopus)

Selective Intracellular Delivery of Ganglioside GM3-Binding Peptide through Caveolae/Raft-Mediated Endocytosis

Matsubara, T., Otani, R., Yamashita, M., Maeno, H., Nodono, H. & Sato, T., 2017 Feb 13, In : Biomacromolecules. 18, 2, p. 355-362 8 p.

Research output: Contribution to journalArticle

G(M3) Ganglioside
Peptides
Avidin
Proteins
Green Fluorescent Proteins
11 Citations (Scopus)

Size and Shape of Amyloid Fibrils Induced by Ganglioside Nanoclusters: Role of Sialyl Oligosaccharide in Fibril Formation

Matsubara, T., Nishihara, M., Yasumori, H., Nakai, M., Yanagisawa, K. & Sato, T., 2017 Dec 5, In : Langmuir. 33, 48, p. 13874-13881 8 p.

Research output: Contribution to journalArticle

Oligosaccharides
Gangliosides
Nanoclusters
nanoclusters
Amyloid
3 Citations (Scopus)

Spirolactam capped cyanine dyes for designing NIR probes to target multiple metal ions

Kar, C., Shindo, Y., Oka, K., Nishiyama, S., Suzuki, K. & Citterio, D., 2017, In : RSC Advances. 7, 40, p. 24970-24980 11 p.

Research output: Contribution to journalArticle

Metal ions
Coloring Agents
Dyes
Ions
Infrared radiation
4 Citations (Scopus)

The identification of D-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis

Kobayashi, K., Maezawa, T., Tanaka, H., Onuki, H., Horiguchi, Y., Hirota, H., Ishida, T., Horiike, K., Agata, Y., Aoki, M., Hoshi, M. & Matsumoto, M., 2017 Mar 24, In : Scientific Reports. 7, 45175.

Research output: Contribution to journalArticle

Planarians
Germ Cells
Tryptophan
Pluripotent Stem Cells
Electrospray Ionization Mass Spectrometry
2 Citations (Scopus)

Three-dimensional kinematic and kinetic analysis of quadrupedal walking in the common marmoset (Callithrix jacchus)

Shimada, H., Kanai, R., Kondo, T., Yoshino-Saito, K., Uchida, A., Nakamura, M., Ushiba, J., Okano, H. & Ogihara, N., 2017, (Accepted/In press) In : Neuroscience Research.

Research output: Contribution to journalArticle

Callithrix
Biomechanical Phenomena
Walking
Locomotion
Macaca
7 Citations (Scopus)

Universal glass-forming behavior of in vitro and living cytoplasm

Nishizawa, K., Fujiwara, K., Ikenaga, M., Nakajo, N., Yanagisawa, M. & Mizuno, D., 2017 Dec 1, In : Scientific Reports. 7, 1, 15143.

Research output: Contribution to journalArticle

cytoplasm
glass
crowding
metabolism
macromolecules
2016
267 Citations (Scopus)

A bacterium that degrades and assimilates poly(ethylene terephthalate)

Yoshida, S., Hiraga, K., Takehana, T., Taniguchi, I., Yamaji, H., Maeda, Y., Toyohara, K., Miyamoto, K., Kimura, Y. & Oda, K., 2016 Mar 11, In : Science. 351, 6278, p. 1196-1199 4 p.

Research output: Contribution to journalArticle

Polyethylene Terephthalates
Bacteria
Ethylene Glycol
Recycling
Enzymes
9 Citations (Scopus)

Altered expression of Mg2+ transport proteins during Parkinson's disease-like dopaminergic cell degeneration in PC12 cells

Shindo, Y., Yamanaka, R., Suzuki, K., Hotta, K. & Oka, K., 2016 Aug 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 8, p. 1979-1984 6 p.

Research output: Contribution to journalArticle

PC12 Cells
Parkinson Disease
Carrier Proteins
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Messenger RNA
1 Citation (Scopus)

An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation

Shindo, Y., Komatsu, H., Hotta, K., Ariga, K. & Oka, K., 2016 Jul 4, In : Scientific Reports. 6, 29224.

Research output: Contribution to journalArticle

Acetyl Coenzyme A
Acetylation
Mitochondria
Adenosine Triphosphate
Mitochondrial Proteins
10 Citations (Scopus)

A new therapeutic application of brain-machine interface (BMI) training followed by hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy for patients with severe hemiparetic stroke: A proof of concept study

Kawakami, M., Fujiwara, T., Ushiba, J., Nishimoto, A., Abe, K., Honaga, K., Nishimura, A., Mizuno, K., Kodama, M., Masakado, Y. & Liu, M., 2016, In : Restorative Neurology and Neuroscience. 34, 5, p. 789-797 9 p.

Research output: Contribution to journalArticle

Brain-Computer Interfaces
Stroke
Fingers
Paresis
Therapeutics
5 Citations (Scopus)

Antarlides: A New Type of Androgen Receptor (AR) Antagonist that Overcomes Resistance to AR-Targeted Therapy

Saito, S., Fujimaki, T., Panbangred, W., Igarashi, Y. & Imoto, M., 2016 Feb 18, In : Angewandte Chemie - International Edition. 55, 8, p. 2728-2732 5 p.

Research output: Contribution to journalArticle

Androgen Receptor Antagonists
Androgen Receptors
propylene glycol methyl ether
Chemical modification
Androgens
19 Citations (Scopus)

Antiproliferative and apoptosis induction of α-mangostin in T47D breast cancer cells

Kritsanawong, S., Innajak, S., Imoto, M. & Watanapokasin, R., 2016 May 1, In : International Journal of Oncology. 48, 5, p. 2155-2165 11 p.

Research output: Contribution to journalArticle

Apoptosis
Breast Neoplasms
Garcinia mangostana
Mitogen-Activated Protein Kinases
Phosphatidylinositol 3-Kinases
14 Citations (Scopus)

Arylmalonate Decarboxylase-Catalyzed Asymmetric Synthesis of Both Enantiomers of Optically Pure Flurbiprofen

Gaßmeyer, S. K., Wetzig, J., Mügge, C., Assmann, M., Enoki, J., Hilterhaus, L., Zuhse, R., Miyamoto, K., Liese, A. & Kourist, R., 2016 Mar 7, In : ChemCatChem. 8, 5, p. 916-921 6 p.

Research output: Contribution to journalArticle

Flurbiprofen
Enantiomers
enantiomers
Carboxy-Lyases
synthesis
3 Citations (Scopus)

Binding of hemagglutinin and influenza virus to a peptide-conjugated lipid membrane

Matsubara, T., Shibata, R. & Sato, T., 2016 Apr 7, In : Frontiers in Microbiology. 7, APR, 468.

Research output: Contribution to journalArticle

Hemagglutinins
Membrane Lipids
Orthomyxoviridae
Peptides
Phospholipids
16 Citations (Scopus)

Biochemical preparation of cell extract for cell-free protein synthesis without physical disruption

Fujiwara, K. & Doi, N., 2016 Apr 1, In : PLoS One. 11, 4, e0154614.

Research output: Contribution to journalArticle

Cell Extracts
extracts
Proteins
cells
Machinery
9 Citations (Scopus)

Biological activities of unique isoflavones prepared from Apios americana Medik

Kaneta, H., Koda, M., Saito, S., Imoto, M., Kawada, M., Yamazaki, Y., Momose, I. & Shindo, K., 2016, In : Bioscience, Biotechnology and Biochemistry. 80, 4, p. 774-778 5 p.

Research output: Contribution to journalArticle

Glucosidases
Isoflavones
Bioactivity
Estrogens
Antioxidants
16 Citations (Scopus)

Brain-machine interfaces for rehabilitation of poststroke hemiplegia

Ushiba, J. & Soekadar, S. R., 2016, (Accepted/In press) In : Progress in Brain Research.

Research output: Contribution to journalArticle

Brain-Computer Interfaces
Hemiplegia
Rehabilitation
Neuronal Plasticity
Fingers
1 Citation (Scopus)

Chemistry and biology of the compounds that modulate cell migration

Tashiro, E. & Imoto, M., 2016 Mar 1, In : Journal of Industrial Microbiology and Biotechnology. 43, 2-3, p. 213-219 7 p.

Research output: Contribution to journalArticle

Cell Movement
Tumors
Cells
Chemotherapy
Seed
Electronic medical equipment
Health
Analog to digital conversion
1 Citation (Scopus)

Data for behavioral results and brain regions showing a time effect during pair-association retrieval

Jimura, K., Hirose, S., Wada, H., Yoshizawa, Y., Imai, Y., Akahane, M., Machida, T., Shirouzu, I., Koike, Y. & Konishi, S., 2016 Sep 1, In : Data in Brief. 8, p. 891-893 3 p.

Research output: Contribution to journalArticle

brain
activation
performance
time
40 Citations (Scopus)

Detection of Temperature Difference in Neuronal Cells

Tanimoto, R., Hiraiwa, T., Nakai, Y., Shindo, Y., Oka, K., Hiroi, N. & Funahashi, A., 2016 Mar 1, In : Scientific Reports. 6, 22071.

Research output: Contribution to journalArticle

Temperature
Thermogenesis
Hot Temperature
Quantum Dots
Cell Shape
4 Citations (Scopus)

Development of a luminescence-controllable firefly luciferin analogue using selective enzymatic cyclization

Ioka, S., Saitoh, T., Maki, S. A., Imoto, M. & Nishiyama, S., 2016 Nov 24, In : Tetrahedron. 72, 47, p. 7505-7508 4 p.

Research output: Contribution to journalArticle

Firefly Luciferin
Fireflies
Bioluminescence
Cyclization
Luminescence
3 Citations (Scopus)

Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation

Niikura, K., Horisawa, K. & Doi, N., 2016 Jan 1, In : Journal of Biochemistry. 159, 1, p. 123-132 10 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Epidermal Growth Factor Receptor
Peptides
Sea Urchins
Antibodies
6 Citations (Scopus)

Frequency-specific synchronization in the bilateral subthalamic nuclei depending on voluntary muscle contraction and relaxation in patients with parkinson’s disease

Kato, K., Yokochi, F., Iwamuro, H., Kawasaki, T., Hamada, K., Isoo, A., Kimura, K., Okiyama, R., Taniguchi, M. & Ushiba, J., 2016 Mar 30, In : Frontiers in Human Neuroscience. 10, MAR2016, p. 1-13 13 p.

Research output: Contribution to journalArticle

Subthalamic Nucleus
Muscle Relaxation
Muscle Contraction
Parkinson Disease
Skeletal Muscle
46 Citations (Scopus)

Genome sequence and analysis of the Japanese morning glory Ipomoea nil

Hoshino, A., Jayakumar, V., Nitasaka, E., Toyoda, A., Noguchi, H., Itoh, T., Shin, T., Minakuchi, Y., Koda, Y., Nagano, A. J., Yasugi, M., Honjo, M. N., Kudoh, H., Seki, M., Kamiya, A., Shiraki, T., Carninci, P., Asamizu, E., Nishide, H., Tanaka, S. & 14 others, Park, K. I., Morita, Y., Yokoyama, K., Uchiyama, I., Tanaka, Y., Tabata, S., Shinozaki, K., Hayashizaki, Y., Kohara, Y., Suzuki, Y., Sugano, S., Fujiyama, A., Iida, S. & Sakakibara, Y., 2016 Nov 8, In : Nature Communications. 7, 13295.

Research output: Contribution to journalArticle

Ipomoea nil
morning
genome
Sequence Analysis
Convolvulaceae
5 Citations (Scopus)

Heptapeptide ligands against receptor-binding sites of influenza hemagglutinin toward anti-influenza therapy

Matsubara, T., Onishi, A., Yamaguchi, D. & Sato, T., 2016 Mar 1, In : Bioorganic and Medicinal Chemistry. 24, 5, p. 1106-1114 9 p.

Research output: Contribution to journalArticle

Hemagglutinins
Human Influenza
Binding Sites
Ligands
Peptides
25 Citations (Scopus)
Diamond
Boron
N-Acetylneuraminic Acid
Orthomyxoviridae
Electrodes
4 Citations (Scopus)

Identification and characterization of two new 5-keto-4-deoxy-D-Glucarate Dehydratases/Decarboxylases

Pick, A., Beer, B., Hemmi, R., Momma, R., Schmid, J., Miyamoto, K. & Sieber, V., 2016 Nov 17, In : BMC Biotechnology. 16, 1, 80.

Research output: Contribution to journalArticle

Carboxy-Lyases
Cats
Comamonas testosteroni
Glutarates
Enzymes
3 Citations (Scopus)

Identification of novel in vivo obligate GroEL/ES substrates based on data from a cell-free proteomics approach

Niwa, T., Fujiwara, K. & Taguchi, H., 2016 Jan 1, In : FEBS Letters. 590, 2, p. 251-257 7 p.

Research output: Contribution to journalArticle

Proteomics
Chaperonins
Protein Folding
Substrates
Mass Spectrometry
1 Citation (Scopus)
Sulfolobus
Mutagenesis
Enantioselectivity
Archaea
Esterases
1 Citation (Scopus)

In vitro selection of bispecific diabody fragments using covalent bicistronic DNA display

Nakayama, M., Komiya, S., Fujiwara, K., Horisawa, K. & Doi, N., 2016 Sep 16, In : Biochemical and Biophysical Research Communications. 478, 2, p. 606-611 6 p.

Research output: Contribution to journalArticle

Bispecific Antibodies
Immunoglobulin Fragments
Display devices
DNA
Libraries
21 Citations (Scopus)

Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation

Tashiro, E., Henmi, S., Odake, H., Ino, S. & Imoto, M., 2016 Sep 2, In : Biochemical and Biophysical Research Communications. 477, 4, p. 801-806 6 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Mitogen-Activated Protein Kinase Kinases
Cadherins
Epidermal Growth Factor
Down-Regulation
1 Citation (Scopus)

Long time-course monitoring of ZFP809-mediated gene silencing in transgene expression driven by promoters containing MLV-derived PBS

Ichida, Y., Utsunomiya, Y., Tomikawa, J., Nakabayashi, K., Sato, T. & Onodera, M., 2016, In : Bioscience, Biotechnology and Biochemistry. 80, 1, p. 114-120 7 p.

Research output: Contribution to journalArticle

Zinc Fingers
Gene Silencing
Transgenes
Zinc
Genes
1 Citation (Scopus)

Mineralization by Dendritic Oligomers of Apatite-Binding Peptide under Body Fluid Conditions

Hashizume, M., Onogami, A., Iijima, K., Matsubara, T., Uchida, Y. & Sato, T., 2016, In : Kobunshi Ronbunshu. 73, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

body fluid
Apatites
Body fluids
Apatite
Oligomers
23 Citations (Scopus)

Mitochondrial Mg2+ homeostasis decides cellular energy metabolism and vulnerability to stress

Yamanaka, R., Tabata, S., Shindo, Y., Hotta, K., Suzuki, K., Soga, T. & Oka, K., 2016 Jul 26, In : Scientific Reports. 6, 30027.

Research output: Contribution to journalArticle

Energy Metabolism
Homeostasis
Metabolome
Optical Imaging
Mitochondrial Membranes
1 Citation (Scopus)

Multivalent Effect in Influenza Hemagglutinin-Binding Activity of Sugar-Mimic Peptide

Matsubara, T., Onishi, A., Saito, T., Yamaguchi, D. & Sato, T., 2016, In : Kobunshi Ronbunshu. 73, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

influenza
Hemagglutinins
Sugars
peptide
Peptides
1 Citation (Scopus)

Prediction of gene structures from RNA-seq data using dual decomposition

Inatsuki, T., Sato, K. & Sakakibara, Y., 2016 Mar 1, In : IPSJ Transactions on Bioinformatics. 9, p. 1-6 6 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
RNA
Genes
Decomposition
Eukaryota
7 Citations (Scopus)

PURE mRNA display for in vitro selection of single-chain antibodies

Nagumo, Y., Fujiwara, K., Horisawa, K., Yanagawa, H. & Doi, N., 2016 May 1, In : Journal of Biochemistry. 159, 5, p. 519-526 8 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Display devices
Messenger RNA
Proteins
In Vitro Techniques
Sigmoid Colon
Neurons
Rats
Electric currents
6-Cyano-7-nitroquinoxaline-2,3-dione