Department of Biosciences and Informatics

Research Output 1987 2020

Filter
Article
2013
47 Citations (Scopus)

EEG-based classification of imaginary left and right foot movements using beta rebound

Hashimoto, Y. & Ushiba, J., 2013 Nov, In : Clinical Neurophysiology. 124, 11, p. 2153-2160 8 p.

Research output: Contribution to journalArticle

Imagery (Psychotherapy)
Foot
Electroencephalography
Brain-Computer Interfaces
Beta Rhythm
14 Citations (Scopus)
Dalteparin
Protamines
Platelet-Rich Plasma
Platelets
Stem cells
2 Citations (Scopus)

Establishment of a new detection system for the dimerization of IRE1α by BiFC assay

Shinjo, S., Tashiro, E. & Imoto, M., 2013, In : Bioscience, Biotechnology and Biochemistry. 77, 6, p. 1333-1336 4 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Dimerization
Inositol
Assays
Phosphotransferases
84 Citations (Scopus)

Event-related desynchronization reflects downregulation of intracortical inhibition in human primary motor cortex

Takemi, M., Masakado, Y., Liu, M. & Ushiba, J., 2013 Sep 1, In : Journal of Neurophysiology. 110, 5, p. 1158-1166 9 p.

Research output: Contribution to journalArticle

Imagery (Psychotherapy)
Motor Cortex
Down-Regulation
Motor Evoked Potentials
Wrist
16 Citations (Scopus)

Fragmin/protamine microparticles to adsorb and protect HGF and to function as local HGF carriers in vivo

Kishimoto, S., Ishihara, M., Nakamura, S., Fujita, M., Takikawa, M., Sumi, Y., Kiyosawa, T., Sato, T. & Kanatani, Y., 2013 Jan, In : Acta Biomaterialia. 9, 1, p. 4763-4770 8 p.

Research output: Contribution to journalArticle

Dalteparin
Protamines
Hepatocyte Growth Factor
Hepatocytes
Intercellular Signaling Peptides and Proteins
21 Citations (Scopus)

HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type i receptor

Sakata, K., Hara, M., Terada, T., Watanabe, N., Takaya, D., Yaguchi, S. I., Matsumoto, T., Matsuura, T., Shirouzu, M., Yokoyama, S., Yamaguchi, T., Miyazawa, K., Aizaki, H., Suzuki, T., Wakita, T., Imoto, M. & Kojima, S., 2013, In : Scientific Reports. 3, 3243.

Research output: Contribution to journalArticle

Viral Structural Proteins
Growth Factor Receptors
Transforming Growth Factors
Hepacivirus
Liver Cirrhosis
2 Citations (Scopus)

Hereditary spastic paraplegia protein spartin is an FK506-binding protein identified by mRNA display

Tokunaga, M., Shiheido, H., Hayakawa, I., Utsumi, A., Takashima, H., Doi, N., Horisawa, K., Sakuma-Yonemura, Y., Tabata, N. & Yanagawa, H., 2013 Jul 25, In : Chemistry and Biology. 20, 7, p. 935-942 8 p.

Research output: Contribution to journalArticle

Hereditary Spastic Paraplegia
Tacrolimus Binding Proteins
Tacrolimus
Display devices
Messenger RNA
8 Citations (Scopus)

Identification of a cytochrome b5-fusion desaturase responsible for the synthesis of triunsaturated sphingolipid long chain bases in the marine diatom Thalassiosira pseudonana

Michaelson, L. V., Markham, J. E., Zäeuner, S., Matsumoto, M., Chen, M., Cahoon, E. B. & Napier, J. A., 2013 Jun, In : Phytochemistry. 90, p. 50-55 6 p.

Research output: Contribution to journalArticle

Cytochromes b5
Diatoms
sphingolipids
Sphingolipids
Bacillariophyceae
4 Citations (Scopus)

Incorporation of glycosylated amino acid into protein by an in vitro translation system

Matsubara, T., Iijima, K., Watanabe, T., Hohsaka, T. & Sato, T., 2013 Oct 15, In : Bioorganic and Medicinal Chemistry Letters. 23, 20, p. 5634-5636 3 p.

Research output: Contribution to journalArticle

Amino Acids
Transfer RNA
Proteins
Protein Precursors
Streptavidin
5 Citations (Scopus)

Innate sexuality determines the mechanisms of telomere maintenance

Tasaka, K., Yokoyama, N., Nodono, H., Hoshi, M. & Matsumoto, M., 2013, In : International Journal of Developmental Biology. 57, 1, p. 69-72 4 p.

Research output: Contribution to journalArticle

Telomere
Sexuality
Planarians
Maintenance
Reproduction
5 Citations (Scopus)

Intracellular activation of acetyl-CoA by an artificial reaction promoter and its fluorescent detection

Komatsu, H., Shindo, Y., Kawashima, S. A., Yamatsugu, K., Oka, K. & Kanai, M., 2013 Apr 11, In : Chemical Communications. 49, 28, p. 2876-2878 3 p.

Research output: Contribution to journalArticle

Acetylation
Acetyl Coenzyme A
Mitochondria
Rhodamines
Fluorescent Dyes
11 Citations (Scopus)

In vivo gene transfer using pDNA/chitosan/chondroitin sulfate ternary complexes: Influence of chondroitin sulfate on the stability of freeze-dried complexes and transgene expression in vivo

Hagiwara, K., Kishimoto, S., Ishihara, M., Koyama, Y., Mazda, O. & Sato, T., 2013 Feb, In : Journal of Gene Medicine. 15, 2, p. 83-92 10 p.

Research output: Contribution to journalArticle

Chondroitin Sulfates
Transgenes
Plasmids
Chitosan
Transfection
9 Citations (Scopus)

Involvement of Ext1 and heparanase in migration of mouse FBJ osteosarcoma cells

Wang, Y., Yang, X., Yamagata, S., Yamagata, T. & Sato, T., 2013 Jan, In : Molecular and Cellular Biochemistry. 373, 1-2, p. 63-72 10 p.

Research output: Contribution to journalArticle

Heparitin Sulfate
Osteosarcoma
Glycosaminoglycans
Biosynthesis
Oligosaccharides
9 Citations (Scopus)

LibSBMLSim: A reference implementation of fully functional SBML simulator

Takizawa, H., Nakamura, K., Tabira, A., Chikahara, Y., Matsui, T., Hiroi, N. & Funahashi, A., 2013 Jun 1, In : Bioinformatics. 29, 11, p. 1474-1476 3 p.

Research output: Contribution to journalArticle

Markup languages
Systems Biology
Simulator
Language
Simulators

Meeting report of the international workshop on quantitative biology 2012: Mesoscopic and microscopic worlds meet

Draviam, V. M., Funahashi, A., Hiroi, N., Kimura, A. & Kobayashi, T. J., 2013, In : Frontiers in Physiology. 3 JAN, Article 479.

Research output: Contribution to journalArticle

Education
4 Citations (Scopus)

MIP-2A Is a Novel Target of an Anilinoquinazoline Derivative for Inhibition of Tumour Cell Proliferation

Tokunaga, M., Shiheido, H., Tabata, N., Sakuma-Yonemura, Y., Takashima, H., Horisawa, K., Doi, N. & Yanagawa, H., 2013 Sep 30, In : PLoS One. 8, 9, e76774.

Research output: Contribution to journalArticle

Cell proliferation
Tumors
cell proliferation
Cells
Cell Proliferation
10 Citations (Scopus)

Neuropeptides trigger oocyte maturation and subsequent spawning in the hydrozoan jellyfish Cytaeis uchidae

Takeda, N., Nakajima, Y., Koizumi, O., Fujisawa, T., Takahashi, T., Matsumoto, M. & Deguchi, R., 2013 Mar, In : Molecular Reproduction and Development. 80, 3, p. 223-232 10 p.

Research output: Contribution to journalArticle

Neuropeptides
Oocytes
Hydra
Epithelium
Peptides
16 Citations (Scopus)

NO/cGMP/PKG signaling pathway induces magnesium release mediated by mitoKATP channel opening in rat hippocampal neurons

Yamanaka, R., Shindo, Y., Hotta, K., Suzuki, K. & Oka, K., 2013 Aug 19, In : FEBS Letters. 587, 16, p. 2643-2648 6 p.

Research output: Contribution to journalArticle

Magnesium
Neurons
Rats
Diazoxide
Mitochondria
2 Citations (Scopus)

Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase

Magi, S., Shitara, T., Takemoto, Y., Sawada, M., Kitagawa, M., Tashiro, E., Takahashi, Y. & Imoto, M., 2013 Mar, In : Journal of Antibiotics. 66, 3, p. 165-170 6 p.

Research output: Contribution to journalArticle

Aclarubicin
Cell Migration Inhibition
Transferases
Neoplasms
Phosphatidylinositol 3-Kinases
20 Citations (Scopus)

Novel isoflavone glucosides in groundnut (Apios americana medik) and their antiandrogenic activities

Ichige, M., Fukuda, E., Miida, S., Hattan, J. I., Misawa, N., Saito, S., Fujimaki, T., Imoto, M. & Shindo, K., 2013 Mar 6, In : Journal of Agricultural and Food Chemistry. 61, 9, p. 2183-2187 5 p.

Research output: Contribution to journalArticle

Apios americana
genistin
Isoflavones
genistein
Glucosides
5 Citations (Scopus)

Odorant-induced membrane potential depolarization of AIY interneuron in Caenorhabditis elegans

Shidara, H., Kobayashi, J., Tanamoto, R., Hotta, K. & Oka, K., 2013 Apr 29, In : Neuroscience Letters. 541, p. 199-203 5 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Interneurons
Membrane Potentials
Carisoprodol
Neurites
43 Citations (Scopus)

On-demand control system for deep brain stimulation for treatment of intention tremor

Yamamoto, T., Katayama, Y., Ushiba, J., Yoshino, H., Obuchi, T., Kobayashi, K., Oshima, H. & Fukaya, C., 2013 May, In : Neuromodulation. 16, 3, p. 230-235 6 p.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Tremor
Therapeutics
Cerebellar Ataxia
Fourier Analysis
9 Citations (Scopus)
Reaction Time
Muscles
Isometric Contraction
Healthy Volunteers
Sensorimotor Cortex
5 Citations (Scopus)

Raman Spectroscopic Imaging of the Whole Ciona intestinalis Embryo during Development

Nakamura, M. J., Hotta, K. & Oka, K., 2013 Aug 20, In : PLoS One. 8, 8, e71739.

Research output: Contribution to journalArticle

Ciona intestinalis
Embryonic Development
embryo (animal)
embryogenesis
Embryonic Structures
12 Citations (Scopus)

Relationship between event-related desynchronization and cortical excitability in healthy subjects and stroke patients

Aono, K., Miyashita, S., Fujiwara, Y., Kodama, M., Hanayama, K., Masakado, Y. & Ushiba, J., 2013, In : Tokai Journal of Experimental and Clinical Medicine. 38, 4, p. 123-128 6 p.

Research output: Contribution to journalArticle

Motor Evoked Potentials
Healthy Volunteers
Stroke
Imagery (Psychotherapy)
Transcranial Magnetic Stimulation
6 Citations (Scopus)

Resonance between cortex and muscle: A determinant of motor precision?

Ushiyama, J. & Ushiba, J., 2013 Jan, In : Clinical Neurophysiology. 124, 1, p. 5-7 3 p.

Research output: Contribution to journalArticle

Efferent Pathways
Motor Cortex
Electromyography
Electroencephalography
Skeletal Muscle
7 Citations (Scopus)
Lateral Ventricles
Primates
Pressure
Population
Genes
3 Citations (Scopus)

Singing-related activity in anterior forebrain of male zebra finches reflects courtship motivation for target females

Iwasaki, M., Poulsen, T. M., Oka, K. & Hessler, N. A., 2013 Nov 29, In : PLoS One. 8, 11, e81725.

Research output: Contribution to journalArticle

Finches
Courtship
Singing
Taeniopygia guttata
Equidae
12 Citations (Scopus)

State of intracortical inhibitory interneuron activity in patients with chronic stroke

Honaga, K., Fujiwara, T., Tsuji, T., Hase, K., Ushiba, J. & Liu, M., 2013 Feb, In : Clinical Neurophysiology. 124, 2, p. 364-370 7 p.

Research output: Contribution to journalArticle

Interneurons
Stroke
Fingers
Paresis
Upper Extremity
5 Citations (Scopus)

Targeted gene delivery in the cricket brain, using in vivo electroporation

Matsumoto, C. S., Shidara, H., Matsuda, K., Nakamura, T., Mito, T., Matsumoto, Y., Oka, K. & Ogawa, H., 2013 Dec, In : Journal of Insect Physiology. 59, 12, p. 1235-1241 7 p.

Research output: Contribution to journalArticle

Gryllidae
Electroporation
electroporation
gene transfer
brain
7 Citations (Scopus)

Thermally driven asymmetric domino reaction catalyzed by a thermostable esterase and its variants

Wada, R., Kumon, T., Kourist, R., Ohta, H., Uemura, D., Yoshida, S. & Miyamoto, K., 2013 Apr 10, In : Tetrahedron Letters. 54, 15, p. 1921-1923 3 p.

Research output: Contribution to journalArticle

Esterases
Catalytic Domain
Sulfolobus
Stereoselectivity
Decarboxylation
19 Citations (Scopus)

The systems biology simulation core algorithm

Keller, R., Dörr, A., Tabira, A., Funahashi, A., Ziller, M. J., Adams, R., Rodriguez, N., Novère, N. L., Hiroi, N., Planatscher, H., Zell, A. & Dräger, A., 2013 Jul 5, In : BMC Systems Biology. 7, 55.

Research output: Contribution to journalArticle

Systems Biology
Simulation
Binary codes
Mathematics
Binary Code
4 Citations (Scopus)

Three-dimensional culture using human plasma-medium gel with fragmin/protamine microparticles for proliferation of various human cells

Kishimoto, S., Ishihara, M., Takikawa, M., Takikawa, M., Sumi, Y., Nakamura, S., Fujita, M., Sato, T. & Kiyosawa, T., 2013, (Accepted/In press) In : Cytotechnology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Dalteparin
Plasma (human)
Protamines
Macrophages
Endothelial cells
1 Citation (Scopus)

Use of a cane for recovery from backward balance loss during treadmill walking

Hyodo, M., Saito, M., Ushiba, J., Tomita, Y. & Masakado, Y., 2013 Jun, In : Somatosensory and Motor Research. 30, 2, p. 65-71 7 p.

Research output: Contribution to journalArticle

Canes
Walking
Hand
Healthy Volunteers
Spine
2012
7 Citations (Scopus)

A chemical genomic study identifying diversity in cell migration signaling in cancer cells

Magi, S., Tashiro, E. & Imoto, M., 2012, In : Scientific Reports. 2, 823.

Research output: Contribution to journalArticle

Cell Movement
Cluster Analysis
Neoplasms
Glycogen Synthase Kinase 3
Wound Healing
10 Citations (Scopus)

An Anilinoquinazoline Derivative Inhibits Tumor Growth through Interaction with hCAP-G2, a Subunit of Condensin II

Shiheido, H., Naito, Y., Kimura, H., Genma, H., Takashima, H., Tokunaga, M., Ono, T., Hirano, T., Du, W., Yamada, T., Doi, N., Iijima, S., Hattori, Y. & Yanagawa, H., 2012 Sep 13, In : PLoS One. 7, 9, e44889.

Research output: Contribution to journalArticle

myeloma
Chromosomes
Tumors
chemical derivatives
Cells
8 Citations (Scopus)

Anticipatory postural adjustments contribute to age-related changes in compensatory steps associated with unilateral perturbations

Hyodo, M., Saito, M., Ushiba, J., Tomita, Y., Minami, M. & Masakado, Y., 2012 Jul, In : Gait and Posture. 36, 3, p. 625-630 6 p.

Research output: Contribution to journalArticle

Foot
2 Citations (Scopus)

Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-17

Kiga, M., Tanzawa, F., Iwasaki, S., Inaba, F., Fujiwara, K., Iwadare, H., Echigo, T., Nakamura, Y., Shibata, T., Suzuki, K., Yasumatsu, I., Nakayama, A., Sasazawa, Y., Tashiro, E., Imoto, M. & Kurakata, S., 2012 Jan, In : Anti-Cancer Drugs. 23, 1, p. 119-130 12 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinases
Signal Transduction
Phosphotransferases
SMK-17
22 Citations (Scopus)

A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma

Shiheido, H., Terada, F., Tabata, N., Hayakawa, I., Matsumura, N., Takashima, H., Ogawa, Y., Du, W., Yamada, T., Shoji, M., Sugai, T., Doi, N., Iijima, S., Hattori, Y. & Yanagawa, H., 2012 Jun 25, In : PLoS One. 7, 6, e38878.

Research output: Contribution to journalArticle

phthalimide
myeloma
Multiple Myeloma
Cluster Analysis
Derivatives
5 Citations (Scopus)

A pilot study of contralateral homonymous muscle activity simulated electrical stimulation in chronic hemiplegia

Osu, R., Otaka, Y., Ushiba, J., Sakata, S., Yamaguchi, T., Fujiwara, T., Kondo, K. & Liu, M., 2012 Aug, In : Brain Injury. 26, 9, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

Hemiplegia
Electric Stimulation
Muscles
Hand
Wrist
29 Citations (Scopus)

Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes

Yamamoto, N., Matsubara, T., Sobue, K., Tanida, M., Kasahara, R., Naruse, K., Taniura, H., Sato, T. & Suzuki, K., 2012 May, In : Journal of Neurochemistry. 121, 4, p. 619-628 10 p.

Research output: Contribution to journalArticle

G(M1) Ganglioside
Cluster Analysis
Insulin Resistance
Brain
Insulin Receptor
5 Citations (Scopus)

Calcium phosphate mineralization induced by synthetic peptides having different distributions in simulated body fluids

Hashizume, M., Kamaya, N., Uchida, Y., Matsubara, T. & Sato, T., 2012, In : Chemistry Letters. 41, 6, p. 588-590 3 p.

Research output: Contribution to journalArticle

Body fluids
Durapatite
Peptides
Substrates
calcium phosphate
6 Citations (Scopus)

Calcium regulates caveolin-1 expression at the transcriptional level

Yang, X. Y., Huang, C. C., Kan, Q. M., Li, Y., Liu, D., Zhang, X. C., Sato, T., Yamagata, S. & Yamagata, T., 2012 Sep 28, In : Biochemical and Biophysical Research Communications. 426, 3, p. 334-341 8 p.

Research output: Contribution to journalArticle

Caveolin 1
Calcium
NFATC Transcription Factors
L-Type Calcium Channels
Calcium Signaling
4 Citations (Scopus)

Carbohydrate recognition by pentadecapeptide ligands for a series of sialylated oligosaccharides

Matsubara, T., Onishi, A. & Sato, T., 2012 Nov 1, In : Bioorganic and Medicinal Chemistry. 20, 21, p. 6452-6458 7 p.

Research output: Contribution to journalArticle

Oligosaccharides
Carbohydrates
Ligands
Peptides
Sialic Acids
6 Citations (Scopus)

Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications

Kobayashi, H., Harada, H., Nakamura, M., Futamura, Y., Ito, A., Yoshida, M., Iemura, S. I., Shin-Ya, K., Doi, T., Takahashi, T., Natsume, T., Imoto, M. & Sakakibara, Y., 2012, In : BMC Chemical Biology. 12, 2.

Research output: Contribution to journalArticle

Screening
Proteins
Computer Simulation
Affinity chromatography
Network protocols
10 Citations (Scopus)

Construction of a metagenomic library for the marine sponge Halichondria okadai

Abe, T., Sahin, F. P., Akiyama, K., Naito, T., Kishigami, M., Miyamoto, K., Sakakibara, Y. & Uemura, D., 2012, In : Bioscience, Biotechnology and Biochemistry. 76, 4, p. 633-639 7 p.

Research output: Contribution to journalArticle

Metagenomics
Porifera
Bacteria
Centrifugation
DNA
30 Citations (Scopus)

Contraction level-related modulation of corticomuscular coherence differs between the tibialis anterior and soleus muscles in humans

Ushiyama, J., Masakado, Y., Fujiwara, T., Tsuji, T., Hase, K., Kimura, A., Liu, M. & Ushiba, J., 2012 Apr 15, In : Journal of Applied Physiology. 112, 8, p. 1258-1267 10 p.

Research output: Contribution to journalArticle

Electromyography
Electroencephalography
Skeletal Muscle
Muscles
Isometric Contraction
11 Citations (Scopus)

COPICAT: A software system for predicting interactions between proteins and chemical compounds

Sakakibara, Y., Hachiya, T., Uchida, M., Nagamine, N., Sugawara, Y., Yokota, M., Nakamura, M., Popendorf, K., Komori, T. & Sato, K., 2012 Mar, In : Bioinformatics. 28, 5, p. 745-746 2 p., bts031.

Research output: Contribution to journalArticle

Chemical compounds
Software System
Software
Lead compounds
Proteins
17 Citations (Scopus)

DAFS: Simultaneous aligning and folding of RNA sequences via dual decomposition

Sato, K., Kato, Y., Akutsu, T., Asai, K. & Sakakibara, Y., 2012 Dec, In : Bioinformatics. 28, 24, p. 3218-3224 7 p.

Research output: Contribution to journalArticle

Folding
RNA
Alignment
Decomposition
Decompose