Faculty of Pharmacy

Research Output

2020

A case of intrahepatic cholangiocellular carcinoma due to thorotrast deposition, well-controlled by radiofrequency ablation therapy

Taniki, N., Nakamoto, N., Yoshida, A., Chu, P. S., Ikura, A., Yamataka, K., Morikawa, R., Shiba, S., Yamaguchi, A., Usui, S., Ojiro, K., Ebinuma, H., Saito, H., Kubota, N., Masugi, Y., Sakamto, M. & Kanai, T., 2020, In : Acta Hepatologica Japonica. 61, 5, p. 262-269 8 p.

Research output: Contribution to journalArticle

Open Access

Accumulation of major linezolid metabolites in patients with renal impairment

Souza, E., Crass, R. L., Felton, J., Hanaya, K. & Pai, M. P., 2020 May 1, In : Antimicrobial Agents and Chemotherapy. 64, 5, e00027-20.

Research output: Contribution to journalArticle

A lipidome atlas in MS-DIAL 4

Tsugawa, H., Ikeda, K., Takahashi, M., Satoh, A., Mori, Y., Uchino, H., Okahashi, N., Yamada, Y., Tada, I., Bonini, P., Higashi, Y., Okazaki, Y., Zhou, Z., Zhu, Z. J., Koelmel, J., Cajka, T., Fiehn, O., Saito, K., Arita, M. & Arita, M., 2020, (Accepted/In press) In : Nature Biotechnology.

Research output: Contribution to journalArticle

Analyzing Upward Deviation of Actual vs Predicted Drug Sales in Japan for a Reasonable Drug-Pricing Policy

Shibata, S., Fukumoto, D., Suzuki, T. & Ozaki, K., 2020 Jan 1, (Accepted/In press) In : Therapeutic Innovation and Regulatory Science.

Research output: Contribution to journalArticle

A Nationwide, Multicenter Registry Study of Antiemesis for Carboplatin-Based Chemotherapy-Induced Nausea and Vomiting in Japan

Iihara, H., Shimokawa, M., Hayashi, T., Kawazoe, H., Saeki, T., Aiba, K. & Tamura, K., 2020 Feb 1, In : Oncologist. 25, 2, p. e373-e380

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Antioxidant vitamins and lysophospholipids are critical for inducing mouse spermatogenesis under organ culture conditions

Sanjo, H., Yao, T., Katagiri, K., Sato, T., Matsumura, T., Komeya, M., Yamanaka, H., Yao, M., Matsuhisa, A., Asayama, Y., Ikeda, K., Kano, K., Aoki, J., Arita, M. & Ogawa, T., 2020 Jul 1, In : FASEB Journal. 34, 7, p. 9480-9497 18 p.

Research output: Contribution to journalArticle

Open Access

A phenylphthalimide derivative, TC11, induces apoptosis by degrading MCL1 in multiple myeloma cells

Ichikawa, D., Nakamura, M., Murota, W., Osawa, S., Matsushita, M., Yanagawa, H. & Hattori, Y., 2020 Jan 1, In : Biochemical and Biophysical Research Communications. 521, 1, p. 252-258 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A prospective trial of vaccine to prevent hepatitis B virus reactivation after hematopoietic stem cell transplantation

Nishikawa, K., Kimura, K., Kanda, Y., Sugiyama, M., Kakihana, K., Doki, N., Ohashi, K., Bae, S. K., Takahashi, K., Ishihara, Y., Mizuno, I., Onishi, Y., Onozawa, M., Onizuka, M., Yamamoto, M., Ishikawa, T., Inoue, K., Kusumoto, S., Hashino, S., Saito, H. & 3 others, Kanto, T., Sakamaki, H. & Mizokami, M., 2020 Jul 1, In : Bone Marrow Transplantation. 55, 7, p. 1388-1398 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model

Abe, Y., Ikegawa, N., Yoshida, K., Muramatsu, K., Hattori, S., Kawai, K., Murakami, M., Tanaka, T., Goda, W., Goto, M., Yamamoto, T., Hashimoto, T., Yamada, K., Shibata, T., Misawa, H., Mimura, M., Tanaka, K. F., Miyakawa, T., Iwatsubo, T., Hata, J. I. & 2 others, Niikura, T. & Yasui, M., 2020 May 12, In : Acta Neuropathologica Communications. 8, 1, 67.

Research output: Contribution to journalArticle

Open Access

Carbon monoxide rescues the developmental lethality of experimental rat models of rhabdomyolysis-induced acute kidney injury

Taguchi, K., Ogaki, S., Nagasaki, T., Yanagisawa, H., Nishida, K., Maeda, H., Enoki, Y., Matsumoto, K., Sekijima, H., Ooi, K., Ishima, Y., Watanabe, H., Fukagawa, M., Otagiri, M. & Maruyama, T., 2020 Mar, In : Journal of Pharmacology and Experimental Therapeutics. 372, 3, p. 355-365 11 p.

Research output: Contribution to journalArticle

Catalytic residues, substrate specificity, and role in carbon starvation of the 2-hydroxy FA dioxygenase Mpo1 in yeast

Mori, K., Obara, T., Seki, N., Miyamoto, M., Naganuma, T., Kitamura, T. & Kihara, A., 2020 Jul 1, In : Journal of lipid research. 61, 7, p. 1104-1114 11 p.

Research output: Contribution to journalArticle

Open Access

Cell uptake and anti-tumor effect of liposomes containing encapsulated paclitaxel-bound albumin against breast cancer cells in 2D and 3D cultured models

Okamoto, Y., Taguchi, K., Imoto, S., Giam Chuang, V. T., Yamasaki, K. & Otagiri, M., 2020 Feb, In : Journal of Drug Delivery Science and Technology. 55, 101381.

Research output: Contribution to journalArticle

Characterization of the Interaction of Daptomycin with Site II on Human Serum Albumin

Yamasaki, K., Sakurama, K., Nishi, K., Watanabe, H., Maruyama, T., Seo, H., Otagiri, M. & Taguchi, K., 2020, (Accepted/In press) In : Journal of Pharmaceutical Sciences.

Research output: Contribution to journalArticle

Clinical implications with tolvaptan on monitored bioimpedance-defined fluid status in patients with cirrhotic ascites: An observational study

Shiba, S., Chu, P. S., Nakamoto, N., Yamataka, K., Taniki, N., Ojiro, K., Yamaguchi, A., Morikawa, R., Yoshida, A., Ikura, A., Ebinuma, H., Saito, H. & Kanai, T., 2020 Mar 5, In : BMC Gastroenterology. 20, 1, 53.

Research output: Contribution to journalArticle

Open Access

Commensal-bacteria-derived butyrate promotes the t-cell-independent iga response in the colon

Isobe, J., Maeda, S., Obata, Y., Iizuka, K., Nakamura, Y., Fujimura, Y., Kimizuka, T., Hattori, K., Kim, Y. G., Morita, T., Kimura, I., Offermanns, S., Adachi, T., Nakao, A., Kiyono, H., Takahashi, D. & Hase, K., 2020 Apr 1, In : International immunology. 32, 4, p. 243-258 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Comprehensive semisyntheses of catathelasmols C, D, and E from D-glutamic acid, utilizing lipase-catalyzed site-selective reactions on intermediates

Hashiba, R., Hashimoto, R., Nishiguchi, M., Kobayashi, T., Hanaya, K., Higashibayashi, S. & Sugai, T., 2020 Jul 2, In : Bioscience, Biotechnology and Biochemistry. 84, 7, p. 1339-1344 6 p.

Research output: Contribution to journalArticle

Concurrent administration with multivalent metal cation preparations or polycationic polymer preparations inhibits the absorption of raltegravir via its chelation

Enoki, Y., Suzuki, N., Ito, M., Uchiyama, E., Kishi, N., Ito, C., Kitahiro, Y., Sakamoto, K., Taguchi, K., Yokoyama, Y., Kizu, J. & Matsumoto, K., 2020, (Accepted/In press) In : Journal of Pharmacy and Pharmacology.

Research output: Contribution to journalArticle

Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction

Inagaki, M., Nishimura, T., Nakanishi, T., Shimada, H., Noguchi, S., Akanuma, S. I., Tachikawa, M., Hosoya, K. I., Tamai, I., Nakashima, E. & Tomi, M., 2020 May 22, In : iScience. 23, 5, 101098.

Research output: Contribution to journalArticle

Open Access

Cysteinyl leukotriene metabolism of human eosinophils in allergic disease

Miyata, J., Fukunaga, K., Kawashima, Y., Ohara, O. & Arita, M., 2020 Jan, In : Allergology International. 69, 1, p. 28-34 7 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Development of a sensitive LC–MS/MS method for quantification of linezolid and its primary metabolites in human serum

Souza, E., Felton, J., Crass, R. L., Hanaya, K. & Pai, M. P., 2020 Jan 30, In : Journal of Pharmaceutical and Biomedical Analysis. 178, 112968.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Development of sustained-release ophthalmic formulation based on tranilast solid nanoparticles

Minami, M., Seiriki, R., Otake, H., Nakazawa, Y., Kanai, K., Tanino, T. & Nagai, N., 2020 Apr 1, In : Materials. 13, 7, 1675.

Research output: Contribution to journalArticle

Open Access

Discrimination of prediction models between cold-heat and deficiency-excess patterns

Maeda-Minami, A., Yoshino, T., Katayama, K., Horiba, Y., Hikiami, H., Shimada, Y., Namiki, T., Tahara, E., Minamizawa, K., Muramatsu, S., Yamaguchi, R., Imoto, S., Miyano, S., Mima, H., Mimura, M., Nakamura, T. & Watanabe, K., 2020 Mar, In : Complementary Therapies in Medicine. 49, 102353.

Research output: Contribution to journalArticle

Echinocandins versus non-echinocandins for empirical antifungal therapy in patients with hematological disease with febrile neutropenia: A systematic review and meta-analysis

Yamashita, C., Takesue, Y., Matsumoto, K., Ikegame, K., Enoki, Y., Uchino, M., Miyazaki, T., Izumikawa, K., Takada, T., Okinaka, K., Ueda, T., Miyazaki, Y. & Mayumi, T., 2020 Jun, In : Journal of Infection and Chemotherapy. 26, 6, p. 596-603 8 p.

Research output: Contribution to journalArticle

Open Access

Echinocandins versus non-echinocandins for the treatment of invasive candidiasis: A meta-analysis of randomized controlled trials

Tashiro, S., Osa, S., Igarashi, Y., Watabe, Y., Liu, X., Enoki, Y., Taguchi, K., Mayumi, T., Miyazaki, Y., Takesue, Y. & Matsumoto, K., 2020, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Effects of arterial hemorrhage speed on the blood coagulation/fibrinolysis system and hemodynamics in rats

Furukawa, S., Sasao, A., Yonemitsu, K., Ohtsu, Y., Tsutsumi, H., Taguchi, K., Otagiri, M. & Nishitani, Y., 2020 Apr 1, In : Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 31, 3, p. 198-206 9 p.

Research output: Contribution to journalArticle

Evasion of the accelerated blood clearance phenomenon by polysarcosine coating of liposomes

Son, K., Ueda, M., Taguchi, K., Maruyama, T., Takeoka, S. & Ito, Y., 2020 Jun 10, In : Journal of Controlled Release. 322, p. 209-216 8 p.

Research output: Contribution to journalArticle

Five new 2-(2-phenylethyl)chromone derivatives from agarwood

Shibata, S., Sugiyama, T., Uekusa, Y., Masui, R., Narukawa, Y. & Kiuchi, F., 2020 Jun 1, In : Journal of Natural Medicines. 74, 3, p. 561-570 10 p.

Research output: Contribution to journalArticle

Formulation development of mucoadhesive microparticle-laden gels for oral mucositis: An in vitro and in vivo study

Sakurai, H., Ikeuchi-Takahashi, Y., Kobayashi, A., Yoshimura, N., Ishihara, C., Aomori, T. & Onishi, H., 2020 Jul, In : Pharmaceutics. 12, 7, p. 1-16 16 p., 603.

Research output: Contribution to journalArticle

Open Access
Open Access

Homeostatic Function of Dermokine in the Skin Barrier and Inflammation

Utsunomiya, A., Chino, T., Utsunomiya, N., Luong, V. H., Tokuriki, A., Naganuma, T., Arita, M., Higashi, K., Saito, K., Suzuki, N., Ohara, A., Sugai, M., Sugawara, K., Tsuruta, D., Oyama, N. & Hasegawa, M., 2020 Apr, In : Journal of Investigative Dermatology. 140, 4, p. 838-849.e9

Research output: Contribution to journalArticle

1 Citation (Scopus)

Inhibitors of the protein–protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line

Yasuda, D., Ohe, T., Takahashi, K., Imamura, R., Kojima, H., Okabe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Nagano, T. & Mashino, T., 2020 Jan 1, (Accepted/In press) In : Free Radical Research.

Research output: Contribution to journalArticle

1 Citation (Scopus)

In vivo evaluation of drug dialyzability in a rat model of hemodialysis

Fukunaga, M., Kadowaki, D., Mori, M., Hagiwara, S., Narita, Y., Saruwatari, J., Tanaka, R., Watanabe, H., Yamasaki, K., Taguchi, K., Ito, H., Maruyama, T., Otagiri, M. & Hirata, S., 2020 Jun, In : PloS one. 15, 6, e0233925.

Research output: Contribution to journalArticle

Open Access

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

Funakoshi-Tago, M., Yu, S., Kushida, A., Takeuchi, K. & Tamura, H., 2020 Mar, In : Heliyon. 6, 3, e03598.

Research output: Contribution to journalArticle

Open Access

LC–MS analysis of saponins of Achyranthes root in the Japanese market

Kuwada, K., Kawase, S., Nakata, K., Shinya, N., Narukawa, Y., Fuchino, H., Kawahara, N. & Kiuchi, F., 2020 Jan 1, In : Journal of Natural Medicines. 74, 1, p. 135-141 7 p.

Research output: Contribution to journalArticle

Liquid Formulation of Gemcitabine Increases Venous Pain in Patients With Cancer: A Retrospective Study

Kawazoe, H., Mori, N., Ido, S., Uozumi, R., Tsuneoka, K., Takeuchi, A., Matsuo, M., Yamauchi, M., Nakai, M., Sumikawa, S., Nakamura, T. & Yakushijin, Y., 2020 Apr, In : Clinical Therapeutics. 42, 4, p. 712-719 8 p.

Research output: Contribution to journalArticle

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Kimura, I., Miyamoto, J., Ohue-Kitano, R., Watanabe, K., Yamada, T., Onuki, M., Aoki, R., Isobe, Y., Kashihara, D., Inoue, D., Inaba, A., Takamura, Y., Taira, S., Kumaki, S., Watanabe, M., Ito, M., Nakagawa, F., Irie, J., Kakuta, H., Shinohara, M. & 6 others, Iwatsuki, K., Tsujimoto, G., Ohno, H., Arita, M., Itoh, H. & Hase, K., 2020 Feb 28, In : Science. 367, 6481, eaaw8429.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice

Hirata, S. I., Nagatake, T., Sawane, K., Hosomi, K., Honda, T., Ono, S., Shibuya, N., Saito, E., Adachi, J., Abe, Y., Isoyama, J., Suzuki, H., Matsunaga, A., Tomonaga, T., Kiyono, H., Kabashima, K., Arita, M. & Kunisawa, J., 2020 Aug 1, In : Allergy: European Journal of Allergy and Clinical Immunology. 75, 8, p. 1935-1951 17 p.

Research output: Contribution to journalArticle

Open Access

Medications and fall risk: a case–control study in nursing home residents in Japan

Park, H., Satoh, H., Miki, A., Maki, H., Asai, K., Shiraishi, A., Urushihara, H. & Sawada, Y., 2020 May 1, In : Aging Clinical and Experimental Research. 32, 5, p. 885-892 8 p.

Research output: Contribution to journalArticle

Meta-Analysis Comparing Direct Oral Anticoagulants Versus Warfarin in Morbidly Obese Patients With Atrial Fibrillation

Kido, K., Shimizu, M., Shiga, T. & Hashiguchi, M., 2020 Jul 1, In : American Journal of Cardiology. 126, p. 23-28 6 p.

Research output: Contribution to journalArticle

Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity

Nakamura, Y., Mimuro, H., Kunisawa, J., Furusawa, Y., Takahashi, D., Fujimura, Y., Kaisho, T., Kiyono, H. & Hase, K., 2020 Jul 1, In : Mucosal Immunology. 13, 4, p. 679-690 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Novel sustained‐release drug delivery system for dry eye therapy by rebamipide nanoparticles

Nagai, N., Ishii, M., Seiriki, R., Ogata, F., Otake, H., Nakazawa, Y., Okamoto, N., Kanai, K. & Kawasaki, N., 2020 Feb, In : Pharmaceutics. 12, 2, 155.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Of infliximab with long-term administration in Japanese patients with Crohn's disease: Analysis using population pharmacokinetics

Matsuoka, K., Hamada, S., Shimizu, M., Nanki, K., Mizuno, S., Kiyohara, H., Arai, M., Sugimoto, S., Iwao, Y., Ogata, H., Hisamatsu, T., Nagauma, M., Kanai, T., Mochizuki, M. & Hashiguchi, M., 2020, In : International journal of clinical pharmacology and therapeutics. 58, 2, p. 89-102 14 p.

Research output: Contribution to journalArticle

Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation

Nakazawa, Y., Aoki, M., Ishiwa, S., Morishita, N., Endo, S., Nagai, N., Yamamoto, N., Funakoshi-Tago, M. & Tamura, H., 2020 Jan 1, In : Molecular Medicine Reports. 21, 3, p. 1258-1266 9 p.

Research output: Contribution to journalArticle

Open Access

Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity

Kimura, S., Nakamura, Y., Kobayashi, N., Shiroguchi, K., Kawakami, E., Mutoh, M., Takahashi-Iwanaga, H., Yamada, T., Hisamoto, M., Nakamura, M., Udagawa, N., Sato, S., Kaisho, T., Iwanaga, T. & Hase, K., 2020 Dec 1, In : Nature communications. 11, 1, 234.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Oxidative misfolding of Cu/Zn-superoxide dismutase triggered by non-canonical intramolecular disulfide formation

Anzai, I., Tokuda, E., Handa, S., Misawa, H., Akiyama, S. & Furukawa, Y., 2020 Feb 1, In : Free Radical Biology and Medicine. 147, p. 187-199 13 p.

Research output: Contribution to journalArticle