Faculty of Pharmacy

Research Output 1975 2020

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2018
1 Citation (Scopus)

IL-10 promoter transactivation by the viral K-RTA protein involves the host-cell transcription factors, specificity proteins 1 and 3

Miyazawa, M., Noguchi, K., Kujirai, M., Katayama, K., Yamagoe, S. & Sugimoto, Y., 2018 Jan 12, In : Journal of Biological Chemistry. 293, 2, p. 662-676 15 p.

Research output: Contribution to journalArticle

Sp3 Transcription Factor
Sp1 Transcription Factor
Human Herpesvirus 8
Transcription
Interleukin-10
9 Citations (Scopus)

Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system

Saito, Y., Nakaoka, T., Muramatsu, T., Ojima, H., Sukeda, A., Sugiyama, Y., Uchida, R., Furukawa, R., Kitahara, A., Sato, T., Kanai, Y. & Saito, H., 2018 Dec 1, In : Scientific Reports. 8, 1, 2821.

Research output: Contribution to journalArticle

Organoids
Cholangiocarcinoma
Hepatocytes
Intrahepatic Bile Ducts
Cytochrome P-450 CYP3A
7 Citations (Scopus)

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

Komine, O., Yamashita, H., Fujimori-Tonou, N., Koike, M., Jin, S., Moriwaki, Y., Endo, F., Watanabe, S., Uematsu, S., Akira, S., Uchiyama, Y., Takahashi, R., Misawa, H. & Yamanaka, K., 2018 Mar 22, (Accepted/In press) In : Cell Death and Differentiation. p. 1-17 17 p.

Research output: Contribution to journalArticle

Deficiency Diseases
Amyotrophic Lateral Sclerosis
Astrocytes
Disease Progression
Myeloid Differentiation Factor 88
4 Citations (Scopus)

Intestinal epithelial cell-specific deletion of α-mannosidase II ameliorates experimental colitis

Suzuki, K., Yamada, T., Yamazaki, K., Hirota, M., Ishihara, N., Sakamoto, M., Takahashi, D., Iijima, H. & Hase, K., 2018 Jan 1, In : Cell Structure and Function. 43, 1, p. 25-39 15 p.

Research output: Contribution to journalArticle

Colitis
Inflammatory Bowel Diseases
Epithelial Cells
Glycosylation
Chemokines
5 Citations (Scopus)

In vivo drug delivery efficiency of albumin-encapsulated liposomes as hydrophobic drug carriers

Okamoto, Y., Taguchi, K., Sakuragi, M., Imoto, S., Yamasaki, K. & Otagiri, M., 2018 Oct 1, In : Journal of Drug Delivery Science and Technology. 47, p. 62-66 5 p.

Research output: Contribution to journalArticle

Drug Carriers
Liposomes
Albumins
Tacrolimus
Pharmaceutical Preparations
6 Citations (Scopus)

Involvement of endocytosis in the transdermal penetration mechanism of ketoprofen nanoparticles

Nagai, N., Ogata, F., Ishii, M., Fukuoka, Y., Otake, H., Nakazawa, Y. & Kawasaki, N., 2018 Jul 23, In : International Journal of Molecular Sciences. 19, 7, 2138.

Research output: Contribution to journalArticle

Ketoprofen
Endocytosis
Nanoparticles
Skin
penetration
5 Citations (Scopus)

LAT1-targeting thermoresponsive fluorescent polymer probes for cancer cell imaging

Matsuura, M., Ohshima, M., Hiruta, Y., Nishimura, T., Nagase, K. & Kanazawa, H., 2018 Jun 1, In : International Journal of Molecular Sciences. 19, 6, 1646.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
transporter
Fluorescent Dyes
amino acids
Amino acids
19 Citations (Scopus)

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury

Okubo, K., Kurosawa, M., Kamiya, M., Urano, Y., Suzuki, A., Yamamoto, K., Hase, K., Honma, K., Sasaki, J., Miyauchi, H., Hoshino, T., Hayashi, M., Mayadas, T. N. & Hirahashi, J., 2018 Feb 1, In : Nature Medicine. 24, 2, p. 232-238 7 p.

Research output: Contribution to journalArticle

Rhabdomyolysis
Macrophages
Platelet Activation
Platelets
Acute Kidney Injury
2 Citations (Scopus)

Macrophages switch their phenotype by regulating maf expression during different phases of inflammation

Kikuchi, K., Iida, M., Ikeda, N., Moriyama, S., Hamada, M., Takahashi, S., Kitamura, H., Watanabe, T., Hasegawa, Y., Hase, K., Fukuhara, T., Sato, H., Kobayashi, E. H., Suzuki, T., Yamamoto, M., Tanaka, M. & Asano, K., 2018 Jul 15, In : Journal of Immunology. 201, 2, p. 635-651 17 p.

Research output: Contribution to journalArticle

Macrophages
Inflammation
Phenotype
MafF Transcription Factor
Down-Regulation
5 Citations (Scopus)

Mesenchylmal stem cell culture on poly(N-isopropylacrylamide) hydrogel with repeated thermo-stimulation

Akimoto, A. M., Niitsu, E. H., Nagase, K., Okano, T., Kanazawa, H. & Yoshida, R., 2018 Apr 21, In : International Journal of Molecular Sciences. 19, 4, 1253.

Research output: Contribution to journalArticle

stem cells
Hydrogel
Stem cells
stimulation
Cell culture
1 Citation (Scopus)

Molecular Arrangements of Corannulene and Sumanene in Single-Walled Carbon Nanotubes

Iizumi, Y., Liu, Z., Suenaga, K., Okada, S., Higashibayashi, S., Sakurai, H. & Okazaki, T., 2018 Jan 1, (Accepted/In press) In : ChemNanoMat.

Research output: Contribution to journalArticle

Single-walled carbon nanotubes (SWCN)
Photoluminescence spectroscopy
Molecular orientation
Infrared spectroscopy
Microscopic examination
5 Citations (Scopus)

Molecular determinants of sensitivity or resistance of cancer cells toward sanguinarine

Saeed, M. E. M., Mahmoud, N., Sugimoto, Y., Efferth, T. & Abdel-Aziz, H., 2018 Feb 26, In : Frontiers in Pharmacology. 9, FEB, 136.

Research output: Contribution to journalArticle

Drug Resistance
Neoplasms
Epidermal Growth Factor Receptor
Benzophenanthridines
ATP-Binding Cassette Transporters
37 Citations (Scopus)

MS-based lipidomics of human blood plasma: A community-initiated position paper to develop accepted guidelines

Burla, B., Arita, M., Arita, M., Bendt, A. K., Cazenave-Gassiot, A., Dennis, E. A., Ekroos, K., Han, X., Ikeda, K., Liebisch, G., Lin, M. K., Loh, T. P., Meikle, P. J., Orešič, M., Quehenberger, O., Shevchenko, A., Torta, F., Wakelam, M. J. O., Wheelock, C. E. & Wenk, M. R., 2018 Jan 1, In : Journal of Lipid Research. 59, 10, p. 2001-2017 17 p.

Research output: Contribution to journalArticle

Blood
Guidelines
Plasmas
Lipids
Information Dissemination

Nationwide survey on informed consent and ethical review at hospitals conducting post-marketing studies sponsored by pharmaceutical companies

Urushihara, H., Murakami, Y., Matsui, K. & Tashiroc, S., 2018 Jan 1, In : Yakugaku Zasshi. 138, 1, p. 63-71 9 p.

Research output: Contribution to journalArticle

Ethical Review
Marketing
Informed Consent
Pharmaceutical Preparations
Pharmacists
Oxidative stress
Hepatocellular Carcinoma
Oxidative Stress
Antioxidants
Nutrition

Occludin as a functional marker of vascular endothelial cells on tube-forming activity

Kanayasu-Toyoda, T., Ishii-Watabe, A., Kikuchi, Y., Kitagawa, H., Suzuki, H., Tamura, H., Tada, M., Suzuki, T., Mizuguchi, H. & Yamaguchi, T., 2018 Feb 1, In : Journal of Cellular Physiology. 233, 2, p. 1700-1711 12 p.

Research output: Contribution to journalArticle

Occludin
Endothelial cells
Endothelial Cells
Endothelial Progenitor Cells
G2 Phase
1 Citation (Scopus)

Olanzapine plus aprepitant, palonosetron, and dexamethasone for nausea and vomiting in patients with breast cancer receiving anthracycline: A retrospective study

Kawazoe, H., Uozumi, R., Murakami, A., Yamashita, M., Kobayashi-Taguchi, K., Kusakabe, E., Yamasawa, H., Yakushijin, Y., Nakamura, T. & Kamei, Y., 2018 Dec 1, In : Scientific Reports. 8, 1, 16232.

Research output: Contribution to journalArticle

aprepitant
olanzapine
Anthracyclines
Drug Combinations
Nausea
9 Citations (Scopus)

Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome

Kato, T., Yamazaki, K., Nakajima, M., Date, Y., Kikuchi, J., Hase, K., Ohno, H. & Yamazaki, K., 2018 Oct 17, In : mSphere. 3, 5

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Metabolome
Oral Administration
Periodontal Diseases
Serum
4 Citations (Scopus)

Oral vancomycin versus metronidazole for the treatment of Clostridioides difficile infection: Meta-analysis of randomized controlled trials

Igarashi, Y., Tashiro, S., Enoki, Y., Taguchi, K., Matsumoto, K., Ohge, H., Suzuki, H., Nakamura, A., Mori, N., Morinaga, Y., Yamagishi, Y., Yoshizawa, S., Yanagihara, K., Mikamo, H. & Kunishima, H., 2018 Jan 1, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Metronidazole
Vancomycin
Meta-Analysis
Randomized Controlled Trials
Infection

Patient-Related Risk Factors for Nausea and Vomiting with Standard Antiemetics in Patients with Breast Cancer Receiving Anthracycline-Based Chemotherapy: A Retrospective Observational Study

Kawazoe, H., Murakami, A., Yamashita, M., Nishiyama, K., Kobayashi-Taguchi, K., Komatsu, S., Aoki, R., Kusakabe, E., Yamasawa, H., Yakushijin, Y., Nakamura, T. & Kamei, Y., 2018 Jan 1, (Accepted/In press) In : Clinical Therapeutics.

Research output: Contribution to journalArticle

Antiemetics
Anthracyclines
Nausea
Vomiting
Observational Studies
Off-Label Use
Psychotropic Drugs
Prescriptions
Japan
Databases
4 Citations (Scopus)

Persistence of oral antidiabetic treatment for type 2 diabetes characterized by drug class, patient characteristics and severity of renal impairment: A Japanese database analysis

Kadowaki, T., Sarai, N., Hirakawa, T., Taki, K., Iwasaki, K. & Urushihara, H., 2018 Jan 1, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Biguanides
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Databases

Pharmacokinetic and pharmacodynamic studies of pregabalin suppositories based on pharmacological research

Yajima, R., Matsumoto, K., Yokono, K., Watabe, Y., Enoki, Y., Taguchi, K., Ise, Y., Katayama, S. & Kizu, J., 2018 Jan 1, (Accepted/In press) In : Journal of Pharmacy and Pharmacology.

Research output: Contribution to journalArticle

Suppositories
Pharmacokinetics
Pharmacology
Research
Terminally Ill
1 Citation (Scopus)

Population Pharmacokinetics of Intravenous Busulfan in Japanese Pediatric Patients With Primary Immunodeficiency Diseases

Ishiwata, Y., Nagata, M., Tsuge, K., Takahashi, H., Suzuki, S., Imai, K., Takagi, M., Kanegane, H., Morio, T. & Yasuhara, M., 2018 Mar 1, In : Journal of Clinical Pharmacology. 58, 3, p. 327-331 5 p.

Research output: Contribution to journalArticle

Busulfan
Hematopoietic Stem Cell Transplantation
Pharmacokinetics
Pediatrics
Population
2 Citations (Scopus)

Positive predictive value of ICD-10 codes for acute myocardial infarction in Japan: A validation study at a single center

Ando, T., Ooba, N., Mochizuki, M., Koide, D., Kimura, K., Lee, S. L., Setoguchi, S. & Kubota, K., 2018 Nov 26, In : BMC Health Services Research. 18, 1, 895.

Research output: Contribution to journalArticle

Validation Studies
International Classification of Diseases
Japan
Myocardial Infarction
Diagnosis-Related Groups

Preparation of menisdaurigenin and related compounds

Shirakawa, R., Ishikawa, S., Takahasi, M., Ueno, Y., Uekusa, Y., Narukawa, Y., Sugai, T. & Kiuchi, F., 2018 Jan 1, (Accepted/In press) In : Journal of Natural Medicines.

Research output: Contribution to journalArticle

Stereochemistry
Hydrolysis
Enzymatic hydrolysis
Menispermum
Cocculus
2 Citations (Scopus)

Preventive Effects of Renin-Angiotensin System Inhibitors on Oxaliplatin-induced Peripheral Neuropathy: A Retrospective Observational Study

Uchida, M., Kawazoe, H., Takatori, S., Namba, H., Uozumi, R., Tanaka, A., Kawasaki, H. & Araki, H., 2018 Jan 1, (Accepted/In press) In : Clinical Therapeutics.

Research output: Contribution to journalArticle

oxaliplatin
Peripheral Nervous System Diseases
Renin-Angiotensin System
Observational Studies
Retrospective Studies
1 Citation (Scopus)

Protein kinase C alpha-mediated phosphorylation of PIM-1L promotes the survival and proliferation of acute myeloid leukemia cells

Takami, M., Katayama, K., Noguchi, K. & Sugimoto, Y., 2018 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Protein Kinase C-alpha
Phosphorylation
Myeloid Cells
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
3 Citations (Scopus)

Protein purification using solid-phase extraction on temperature-responsive hydrogel-modified silica beads

Okubo, K., Ikeda, K., Oaku, A., Hiruta, Y., Nagase, K. & Kanazawa, H., 2018 Jan 1, (Accepted/In press) In : Journal of Chromatography A.

Research output: Contribution to journalArticle

Hydrogel
Solid Phase Extraction
Silicon Dioxide
Purification
Temperature
3 Citations (Scopus)

Proteogenomic Analyses of Cellular Lysates Using a Phenol-Guanidinium Thiocyanate Reagent

Kawashima, Y., Miyata, J., Watanabe, T., Shioya, J., Arita, M. & Ohara, O., 2018 Jan 1, (Accepted/In press) In : Journal of Proteome Research.

Research output: Contribution to journalArticle

Phenol
RNA
Proteins
HEK293 Cells
Neutrophils
4 Citations (Scopus)

Quantitative analysis of the anti-inflammatory activity of orengedokuto II: berberine is responsible for the inhibition of NO production

Oshima, N., Shimizu, T., Narukawa, Y., Hada, N. & Kiuchi, F., 2018 Apr 18, (Accepted/In press) In : Journal of Natural Medicines. p. 1-9 9 p.

Research output: Contribution to journalArticle

Berberine
Scutellaria
Phellodendron
Nitric Oxide
Anti-Inflammatory Agents
5 Citations (Scopus)
Biological Products
Alcohols
Availability
Enantiomers
Chirality
5 Citations (Scopus)

Reduction of lipid accumulation rescues Bietti's crystalline dystrophy phenotypes

Hata, M., Ikeda, H. O., Iwai, S., Iida, Y., Gotoh, N., Asaka, I., Ikeda, K., Isobe, Y., Hori, A., Nakagawa, S., Yamato, S., Arita, M., Yoshimura, N. & Tsujikawa, A., 2018 Jan 1, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 15, p. 3936-3941 6 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Phenotype
Lipids
Induced Pluripotent Stem Cells
Glucosylceramides
1 Citation (Scopus)

Reelin deficiency leads to aberrant lipid composition in mouse brain

Mizukami, T., Ikeda, K., Shimanaka, Y., Korogi, K., Zhou, C., Takase, H., Tsuiji, H., Kono, N., Kohno, T., Arai, H., Arita, M. & Hattori, M., 2018 Oct 20, In : Biochemical and Biophysical Research Communications. 505, 1, p. 81-86 6 p.

Research output: Contribution to journalArticle

Stearoyl-CoA Desaturase
Brain
Phospholipids
Lipids
Docosahexaenoic Acids

Relationship between medication adherence and glycemic control in Japanese patients with type 2 diabetes

Tominaga, Y., Aomori, T., Hayakawa, T., Morisky, D. E., Takahashi, K. & Mochizuki, M., 2018 Jan 1, In : Pharmazie. 73, 10, p. 609-612 4 p.

Research output: Contribution to journalArticle

Medication Adherence
Type 2 Diabetes Mellitus
Glycosylated Hemoglobin A
Multivariate Analysis
Cross-Sectional Studies
4 Citations (Scopus)

Repurposing of bromocriptine for cancer therapy

Seo, E. J., Sugimoto, Y., Greten, H. J. & Efferth, T., 2018 Oct 8, In : Frontiers in Pharmacology. 9, OCT, 1030.

Research output: Contribution to journalArticle

Bromocriptine
Neoplasms
Therapeutics
Pharmaceutical Preparations
Cell Line

Risk Factor for Diabetes Mellitus and High Blood Glucose With HMG-CoA Reductase Inhibitors Using a Postmarketing Surveillance Database in Japan

Hashiguchi, M., Maruyama, J., Shimizu, M., Takahashi, D. & Shiga, T., 2018 Jan 1, (Accepted/In press) In : Clinical Pharmacology in Drug Development.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Blood Glucose
Diabetes Mellitus
Japan
Databases
1 Citation (Scopus)

Risk factors associated with pseudoaldosteronism in patients with chronic hepatitis: A retrospective cohort study

Komatsu, A., Yoshino, T., Suzuki, T., Nakamura, T., Kanai, T. & Watanabe, K., 2018 Jan 1, (Accepted/In press) In : Basic and Clinical Pharmacology and Toxicology.

Research output: Contribution to journalArticle

Liddle Syndrome
Glycyrrhizic Acid
Chronic Hepatitis
Cohort Studies
Retrospective Studies

Risk factors for hyperuricemia with HMG-CoA reductase inhibitors using a postmarketing surveillance database in Japan

Hashiguchi, M., Hakamata, J., Shimizu, M., Maruyama, J., Shiga, T. & Mochizuki, M., 2018 Jan 1, In : Japanese Journal of Clinical Pharmacology and Therapeutics. 49, 4, p. 145-150 6 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hyperuricemia
Japan
Databases
Uric Acid

Risk factors for rhabdomyolysis with HMG-CoA reductase inhibitors identified using a postmarketing surveillance database in Japan

Hashiguchi, M., Hakamata, J., Shimizu, M., Maruyama, J., Shiga, T. & Mochizuki, M., 2018 Jan 1, In : International Journal of Clinical Pharmacology and Therapeutics. 56, 7, p. 310-320 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Rhabdomyolysis
Japan
Databases
Angiotensin Receptor Antagonists
3 Citations (Scopus)

Roasted Coffee Reduces β-Amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells

Fukuyama, K., Kakio, S., Nakazawa, Y., Kobata, K., Tago, M., Suzuki, T. & Tamura, H., 2018 Jan 1, (Accepted/In press) In : Molecular Nutrition and Food Research.

Research output: Contribution to journalArticle

Amyloid Precursor Protein Secretases
Coffee
roasting
amyloid
pyrocatechol

Role of Pharmacists in Topical Therapy for Onychomycosis in the Home-care Setting

Yamaura, K., Hayashi, N., Imazu, Y., Yoneta, Y., Uchida, E. & Suzuki, J., 2018 Jan 1, In : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 138, 5, p. 615-619 5 p.

Research output: Contribution to journalArticle

Onychomycosis
Home Care Services
Nails
Pharmacists
Tinea

SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes

Moriwaki, Y., Ohno, Y., Ishii, T., Takamura, Y., Kita, Y., Watabe, K., Sango, K., Tsuji, S. & Misawa, H., 2018 Jun 1, In : PLoS One. 13, 6, e0199829.

Research output: Contribution to journalArticle

trans-Golgi Network
endosomes
protein transport
Endosomes
lysosomes

Stability of benzylpenicillin potassium and ampicillin in an elastomeric infusion pump

Nakamura, T., Enoki, Y., Uno, S., Uwamino, Y., Iketani, O., Hasegawa, N. & Matsumoto, K., 2018 Jan 1, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Infusion Pumps
Penicillin G
Ampicillin
Acetates
Anti-Infective Agents
3 Citations (Scopus)

Stereoselective Total Synthesis of Macrophage-Produced Prohealing 14,21-Dihydroxy Docosahexaenoic Acids

Nishimura, K., Sakaguchi, T., Nanba, Y., Suganuma, Y., Morita, M., Hong, S., Lu, Y., Jun, B., Bazan, N. G., Arita, M. & Kobayashi, Y., 2018 Jan 5, In : Journal of Organic Chemistry. 83, 1, p. 154-166 13 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Macrophages
Aldehydes
Nitriles
Lactic Acid
5 Citations (Scopus)
Inwardly Rectifying Potassium Channel
GTP-Binding Proteins
Nuclear magnetic resonance spectroscopy
Ethanol
Neurology

Syntheses of Englerin A, a Potent Renal Cancer Inhibitor

Hagihara, S., Hanaya, K., Sugai, T. & Shoji, M., 2018 Jan 1, (Accepted/In press) In : Asian Journal of Organic Chemistry.

Research output: Contribution to journalArticle

Guaiane Sesquiterpenes
Oxygen
Pharmaceutical Preparations
englerin A
hydrazine
Sulfoxides
Heterocyclic Compounds
sulfoxide
Fluorescence
Aldehydes
Steroids
Lewis Acids
Bromides
Lithium
Drug Resistance
Protein Binding
Adenosine Triphosphate
irinotecan
Breast Neoplasms