Faculty of Pharmacy

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2017

Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3

Ito, A., Okada, Y., Hashita, T., Aomori, T., Hiromura, K., Nojima, Y., Nakamura, T., Araki, T. & Yamamoto, K., 2017 Mar 21, (Accepted/In press) In : Biochemical Genetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation

Yamashita, Y., Biard, A., Hanaya, K., Shoji, M. & Sugai, T., 2017, In : Bioscience, Biotechnology and Biochemistry. 81, 7, p. 1279-1284 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Significant decreases in blood propofol concentrations during adrenalectomy for phaeochromocytoma

Watanabe, T., Hiraoka, H., Araki, T., Nagano, D., Aomori, T., Nakamura, T., Yamamoto, K. & Baba, H., 2017, (Accepted/In press) In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant

Tago, K., Ohta, S., Kashiwada, M., Tago, M., Matsugi, J., Tominaga, S. I. & Yanagisawa, K., 2017, (Accepted/In press) In : Heliyon.

Research output: Contribution to journalArticle

1 Citation (Scopus)

STAT3 and ERK pathways are involved in cell growth stimulation of the ST2/IL1RL1 promoter

Tago, K., Ohta, S., Tago, M., Aoki-Ohmura, C., Matsugi, J., Tominaga, S. I. & Yanagisawa, K., 2017 Feb 1, In : FEBS Open Bio. 7, 2, p. 293-302 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Suppression of infliximab antibody levels by azathioprine in patients with rheumatoid arthritis

Aomori, T., Tsuchiya, A., Suzuki, S., Jibiki, A., Otsuka, N., Ishioka, E., Kaneko, Y., Takeuchi, T. & Nakamura, T., 2017, In : Pharmazie. 72, 2, p. 95-97 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
11 Citations (Scopus)

Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma

Suto, Y., Sato, M., Fujimori, K., Kitabatake, S., Okayama, M., Ichikawa, D., Matsushita, M., Yamagiwa, N., Iwasaki, G., Kiuchi, F. & Hattori, Y., 2017 Oct 1, In : Bioorganic and Medicinal Chemistry Letters. 27, 19, p. 4558-4563 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Synthesis of a C70 Fragment Buckybowl C28H14 from a C60 fragment sumanene

Hishikawa, S., Okabe, Y., Tsuruoka, R., Higashibayashi, S., Ohtsu, H., Kawano, M., Yakiyama, Y. & Sakurai, H., 2017, In : Chemistry Letters. 46, 10, p. 1556-1559 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synthesis of benzyl tetra-O-acetyl-α-L-glucopyranoside from benzyl 2,3-dideoxy-β-D-Erythro-hex-2-enopyranoside

Okazaki, H., Ueda, Y., Hanaya, K., Shoji, M. & Sugai, T., 2017, In : Heterocycles. 95, 2, p. 862-871 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of enantiomerically enriched drug precursors and an insect pheromone via reduction of ketones using commercially available carbonyl reductase screening kit "Chiralscreen® OH"

Nagai, T., Sakurai, S., Natori, N., Hataoka, M., Kinoshita, T., Inoue, H., Hanaya, K., Shoji, M. & Sugai, T., 2017 Jan 14, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

7 Citations (Scopus)
3 Citations (Scopus)

Synthesis of trans,trans,cis-fused tetracyclic skeleton via radical domino cyclization

Furuta, M., Hanaya, K., Sugai, T. & Shoji, M., 2017 Apr 20, In : Tetrahedron. 73, 16, p. 2316-2322 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The use of a temperature-responsive column for the direct analysis of drugs in serum by two-dimensional heart-cutting liquid chromatography

Mikuma, T., Uchida, R., Kajiya, M., Hiruta, Y. & Kanazawa, H., 2017 Feb 1, In : Analytical and Bioanalytical Chemistry. 409, 4, p. 1059-1065 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Three tyrosine residues in the erythropoietin receptor are essential for Janus kinase 2 V617F mutant-induced tumorigenesis

Ueda, F., Tago, K., Tamura, H. & Tago, M., 2017 Feb 3, In : Journal of Biological Chemistry. 292, 5, p. 1826-1846 21 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Tunable Surface Properties of Temperature-Responsive Polymer-Modified Liposomes Induce Faster Cellular Uptake

Wang, J., Ayano, E., Maitani, Y. & Kanazawa, H., 2017 Jan 31, In : ACS Omega. 2, 1, p. 316-325 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2016

A bis-malonic acid fullerene derivative significantly suppressed IL-33-induced IL-6 expression by inhibiting NF-κB activation

Tago, M., Miyagawa, Y., Ueda, F., Mashino, T., Moriwaki, Y., Tago, K., Kasahara, T. & Tamura, H., 2016 Nov 1, In : International Immunopharmacology. 40, p. 254-264 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Actual status of adverse reactions to antimicrobials covered/not covered by a public relief system

Sato, S., Matsumoto, K., Kuroda, Y. & Kizu, J., 2016 Jul 1, In : Japanese Journal of Chemotherapy. 64, 4, p. 656-662 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay

Inami, K., Mine, Y., Kojo, Y., Tanaka, S., Ishikawa, S. & Mochizuki, M., 2016 Jul 28, (Accepted/In press) In : Natural Product Research. p. 1-5 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
7 Citations (Scopus)

Application of Indirect Comparison to the Drug Development Process: Forecasting Direct Comparison Study Results

Kunitomi, T., Hashiguchi, M. & Mochizuki, M., 2016, (Accepted/In press) In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Approaching over 10 000-fold sensitivity increase in chiral capillary electrophoresis: Cation-selective exhaustive injection and sweeping cyclodextrin-modified micellar electrokinetic chromatography

Mikuma, T., Iwata, Y. T., Miyaguchi, H., Kuwayama, K., Tsujikawa, K., Kanamori, T., Kanazawa, H. & Inoue, H., 2016, (Accepted/In press) In : Electrophoresis.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A proline-type fullerene derivative inhibits adipogenesis by preventing PPARγ activation

Tago, M., Hattori, T., Ueda, F., Tago, K., Ohe, T., Mashino, T. & Tamura, H., 2016 Mar 1, In : Biochemistry and Biophysics Reports. 5, p. 259-265 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates high-fat diet-induced adipocyte hypertrophy and systemic glucose intolerance in mice

Kitada, Y., Kajita, K., Taguchi, K., Mori, I., Yamauchi, M., Ikeda, T., Kawashima, M., Asano, M., Kajita, T., Ishizuka, T., Banno, Y., Kojima, I., Chun, J., Kamata, S., Ishii, I. & Morita, H., 2016 May 1, In : Endocrinology. 157, 5, p. 1839-1851 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Coffee induces vascular endothelial growth factor (VEGF) expression in human neuroblastama SH-SY5Y cells

Kakio, S., Tago, M., Kobata, K. & Tamura, H., 2016 Jan 21, (Accepted/In press) In : Nutritional Neuroscience. p. 1-7 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
7 Citations (Scopus)

Contribution of equilibrative nucleoside transporter (ENT) 2 to fluorouracil transport in rat placental trophoblast cells

Takagi, A., Nishimura, T., Akashi, T., Tomi, M. & Nakashima, E., 2016 Jun 20, (Accepted/In press) In : Drug Metabolism and Pharmacokinetics.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Data supporting mitochondrial morphological changes by SPG13-associated HSPD1 mutants

Miyamoto, Y., Tago, M., Hasegawa, N., Eguchi, T., Tanoue, A., Tamura, H. & Yamauchi, J., 2016 Mar 1, In : Data in Brief. 6, p. 482-488 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Design of tetra-arm PEG-crosslinked thermoresponsive hydrogel for 3D cell culture

Akimoto, A. M., Hasuike, E., Tada, H., Nagase, K., Okano, T., Kanazawa, H. & Yoshida, R., 2016, In : Analytical Sciences. 32, 11, p. 1203-1206 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS

Yamanaka, T., Tosaki, A., Miyazaki, H., Kurosawa, M., Koike, M., Uchiyama, Y., Maity, S. N., Misawa, H., Takahashi, R., Shimogori, T., Hattori, N. & Nukina, N., 2016 Sep 30, In : Scientific Reports. 6, 34575.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Distinct Roles for the N-and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation

Kimura, S., Yamashita, M., Yamakami-Kimura, M., Sato, Y., Yamagata, A., Kobashigawa, Y., Inagaki, F., Amada, T., Hase, K., Iwanaga, T., Ohno, H. & Fukai, S., 2016 Sep 15, In : Scientific Reports. 6, 33548.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Disulfide mapping the voltage-sensing mechanism of a voltage-dependent potassium channel

Nozaki, T., Ozawa, S. I., Harada, H., Kimura, T., Osawa, M. & Shimada, I., 2016 Nov 17, In : Scientific Reports. 6, 37303.

Research output: Contribution to journalArticle

1 Citation (Scopus)

EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity

Li, Y., Takahashi, Y., Fujii, S. I., Zhou, Y., Hong, R., Suzuki, A., Tsubata, T., Hase, K. & Wang, J. Y., 2016 Mar 3, In : Nature Communications. 7, 10836.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells

Nonomiya, Y., Noguchi, K., Tanaka, N., Kasagaki, T., Katayama, K. & Sugimoto, Y., 2016 Dec 1, In : Cancer Science. 107, 12, p. 1877-1887 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effect of hesperetin on chaperone activity in selenite-induced cataract

Nakazawa, Y., Oka, M., Tamura, H. & Takehana, M., 2016 Jan 1, In : Open Medicine. 11, 1, p. 183-189 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Eosinophil polyunsaturated fatty acid metabolism and its potential control of inflammation and allergy

Arita, M., 2016 May 20, (Accepted/In press) In : Allergology International.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Epithelium-intrinsic MicroRNAs contribute to mucosal immune homeostasis by promoting M-cell maturation

Nakato, G., Hase, K., Sato, T., Kimura, S., Sakakibara, S., Sugiyama, M., Obata, Y., Hanazato, M., Iwanaga, T. & Ohno, H., 2016 Mar 1, In : PLoS One. 11, 3, e0150379.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Erratum to: LC-MS-based quantification method for Achyranthes root saponins

Kawahara, Y., Hoshino, T., Morimoto, H., Shimizu, T., Narukawa, Y., Fuchino, H., Kawahara, N. & Kiuchi, F., 2016 Apr 1, In : Journal of Natural Medicines. 70, 2, p. 300 1 p.

Research output: Contribution to journalArticle

Evaluating the Effectiveness of Repricing for Market Expansion in the Japanese Drug Pricing System

Shibata, S., Uemura, R. & Suzuki, T., 2016 Nov 1, In : Therapeutic Innovation and Regulatory Science. 50, 6, p. 751-758 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Ex Situ Enantioconvergent Approaches for the Effective Use of Undesired­ Isomers: Stereochemical Convergence of a Substrate with Multiple Chiral Centers and Recycling of a Decarboxylated Byproduct

Yamashita, Y., Kurihara, T., Horiguchi, T., Miki, A., Shoji, M., Sugai, T. & Hanaya, K., 2016 Mar 16, (Accepted/In press) In : Synthesis (Germany).

Research output: Contribution to journalArticle

2 Citations (Scopus)
9 Citations (Scopus)

Fine-tuning of the mucosal barrier and metabolic systems using the diet-microbial metabolite axis

Nagai, M., Obata, Y., Takahashi, D. & Hase, K., 2016 Mar 10, (Accepted/In press) In : International Immunopharmacology.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2 Citations (Scopus)

Identification of approved drugs that inhibit the binding of amyloid β oligomers to ephrin type-B receptor 2

Suzuki, K., Aimi, T., Ishihara, T. & Mizushima, T., 2016, (Accepted/In press) In : FEBS Open Bio.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Identification of novel HLA-A∗24: 02-restricted epitope derived from a homeobox protein expressed in hematological malignancies

Matsushita, M., Otsuka, Y., Tsutsumida, N., Tanaka, C., Uchiumi, A., Ozawa, K., Suzuki, T., Ichikawa, D., Aburatani, H., Okamoto, S., Kawakami, Y. & Hattori, Y., 2016 Jan 1, In : PLoS One. 11, 1, e0146371.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Immobilization of the Gas Signaling Molecule H2S by Radioisotopes: Detection, Quantification, and In Vivo Imaging

Sarkar, S., Ha, Y. S., Soni, N., An, G. I., Lee, W., Kim, M. H., Huynh, P. T., Ahn, H., Bhatt, N., Lee, Y. J., Kim, J. Y., Park, K. M., Ishii, I., Kang, S. G. & Yoo, J., 2016, (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Contribution to journalArticle

11 Citations (Scopus)
9 Citations (Scopus)