School of Pharmaceutical Sciences

Research Output 1976 2020

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Review article
2019
1 Citation (Scopus)

Maintenance of Intestinal Epithelial Homeostasis by Zinc Transporters

Ohashi, W., Hara, T., Takagishi, T., Hase, K. & Fukada, T., 2019 Jan 1, In : Digestive Diseases and Sciences.

Research output: Contribution to journalReview article

Zinc
Homeostasis
Maintenance
Gastrointestinal Diseases
Micronutrients

The Roles of Peyer's Patches and Microfold Cells in the Gut Immune System: Relevance to Autoimmune Diseases

Kobayashi, N., Takahashi, D., Takano, S., Kimura, S. & Hase, K., 2019 Oct 9, In : Frontiers in Immunology. 10, 2345.

Research output: Contribution to journalReview article

Open Access
Peyer's Patches
Autoimmune Diseases
Immune System
Dysbiosis
Antigens
2018

Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2

Yasuda, D., Obata, R., Takahashi, K., Ohe, T. & Mashino, T., 2018 Jan 1, In : Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 138, 8, p. 1059-1065 7 p.

Research output: Contribution to journalReview article

Proteins
Drug Discovery
Kelch-Like ECH-Associated Protein 1
Lead
Protein Stability

Motor neuron heterogeneity and selective vulnerability in ALS

Misawa, H. & Morisaki, Y., 2018 Jan 1, In : Folia Pharmacologica Japonica. 152, 2, p. 64-69 6 p.

Research output: Contribution to journalReview article

Amyotrophic Lateral Sclerosis
Motor Neurons
Osteopontin
Fatigue
Matrix Metalloproteinase 9
15 Citations (Scopus)
brushes
Brushes
Polymers
Actuators
polymerization
57 Citations (Scopus)

Poly(N-isopropylacrylamide)-based thermoresponsive surfaces provide new types of biomedical applications

Nagase, K., Yamato, M., Kanazawa, H. & Okano, T., 2018 Jan 1, In : Biomaterials. 153, p. 27-48 22 p.

Research output: Contribution to journalReview article

Cell Adhesion
Surface Properties
Cell adhesion
Polymerization
Cell Culture Techniques
2017
32 Citations (Scopus)

Expression and function of the cholinergic system in immune cells

Fujii, T., Mashimo, M., Moriwaki, Y., Misawa, H., Ono, S., Horiguchi, K. & Kawashima, K., 2017 Sep 6, In : Frontiers in Immunology. 8, SEP, 1085.

Research output: Contribution to journalReview article

Cholinergic Agents
Immune System
Spleen
Choline O-Acetyltransferase
Acetylcholine
40 Citations (Scopus)

Physiological functions of the cholinergic system in immune cells

Fujii, T., Mashimo, M., Moriwaki, Y., Misawa, H., Ono, S., Horiguchi, K. & Kawashima, K., 2017 May 1, In : Journal of Pharmacological Sciences. 134, 1, p. 1-21 21 p.

Research output: Contribution to journalReview article

Cholinergic Agents
Immune System
Choline O-Acetyltransferase
Dendritic Cells
T-Lymphocytes
1 Citation (Scopus)

Strategic drug design to avoid the metabolic activation of hepatotoxic drugs

Ohe, T., Takahashi, K., Nakamura, S. & Mashino, T., 2017, In : Yakugaku Zasshi. 137, 3, p. 249-255 7 p.

Research output: Contribution to journalReview article

Benzbromarone
Drug Design
Pharmaceutical Preparations
Drug-Related Side Effects and Adverse Reactions
Catechols
2016
1 Citation (Scopus)

Chemical reactions of 8-quinolinol derivatives and their applications to biochemical tools and enzyme inhibitors

Aoki, S., Ariyasu, S., Hanaya, K., Hisamatsu, Y. & Sugai, T., 2016, In : Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 74, 5, p. 482-493 12 p.

Research output: Contribution to journalReview article

Oxyquinoline
Enzyme Inhibitors
Chemical reactions
Derivatives
Materials science
7 Citations (Scopus)

The diet-microbiota-metabolite axis regulates the host physiology

Yamada, T., Takahashi, D. & Hase, K., 2016, In : Journal of Biochemistry. 160, 1, p. 1-10 10 p.

Research output: Contribution to journalReview article

Microbiota
Physiology
Nutrition
Metabolites
Diet