Research Output 1987 2019

2011
8 Citations (Scopus)

Simple autogeneic feeder cell preparation for pluripotent stem cells

Li, W., Yamashita, H., Hattori, F., Chen, H., Tohyama, S., Satoh, Y., Sasaki, E., Yuasa, S., Makino, S., Sano, M. & Fukuda, K., 2011 Jan, In : Stem Cell Research. 6, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Feeder Cells
Callithrix
Pluripotent Stem Cells
Hip
Embryonic Stem Cells

The Overexpression of S105N Mutant Rad Leads Intracellular Ca2+ Overload Via Up-Regulation of Cardiac Ryanodine Receptor Activity

Yamakawa, H., Murata, M., Yada, H., Mizusawa, M., Tohyama, S., Ohgino, Y., Yuasa, S., Makino, S., Sano, M., Fukuda, K., Suzuki, T. & Kamiya, K., 2011, In : Journal of Arrhythmia. 27, 4, p. 275 1 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Cardiac Myocytes
Up-Regulation
Monomeric GTP-Binding Proteins
Calcium
5 Citations (Scopus)
Reference Values
Obesity
Tokyo
Adipose Tissue
Fats
2010
182 Citations (Scopus)

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W. Y., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, O., Kamatani, N., Nakamura, Y. & Kadowaki, T., 2010 Oct, In : Nature Genetics. 42, 10, p. 864-868 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Type 2 Diabetes Mellitus
Population
Chromosomes, Human, Pair 15
Chromosomes, Human, Pair 3
7 Citations (Scopus)

Association of increased reactive oxygen species production with abdominal obesity in type 2 diabetes

Hirao, K., Maruyama, T., Ohno, Y., Hirose, H., Shimada, A., Takei, I., Murata, M., Morii, T., Eguchi, T., Hayashi, M., Saruta, T. & Itoh, H., 2010 Apr, In : Obesity Research and Clinical Practice. 4, 2

Research output: Contribution to journalArticle

Abdominal Obesity
Type 2 Diabetes Mellitus
Reactive Oxygen Species
Body Mass Index
Tetradecanoylphorbol Acetate
1 Citation (Scopus)

Correction: Transmission of Specific Genotype Streptomycin Resistant Strains of Mycobacterium tuberculosis in the Tokyo Metropolitan Area in Japan

Ohkado, A., Murase, Y., Mori, M., Hasegawa, N., Otsuka, G., Nagamine, M., Maeda, H., Uchimura, K., Ohmori, M., Yamada, N., Maeda, S., Kato, S., Mori, T. & Ishikawa, N., 2010 Mar 29, In : BMC Infectious Diseases. 10, 1471.

Research output: Contribution to journalArticle

Tokyo
Streptomycin
Mycobacterium tuberculosis
Japan
Genotype
22 Citations (Scopus)

Elevated serum adiponectin level in patients with mycobacterium avium-intracellulare complex pulmonary disease

Tasaka, S., Hasegawa, N., Nishimura, T., Yamasawa, W., Kamata, H., Shinoda, H., Kimizuka, Y., Fujiwara, H., Hirose, H. & Ishizaka, A., 2010 Apr, In : Respiration. 79, 5, p. 383-387 5 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Adiponectin
Lung Diseases
Leptin
Interleukin-6
9 Citations (Scopus)

Epigenetic control of cardiomyocyte production in response to a stress during the medaka heart development

Taneda, Y., Konno, S., Makino, S., Morioka, M., Fukuda, K., Imai, Y., Kudo, A. & Kawakami, A., 2010 Apr 1, In : Developmental Biology. 340, 1, p. 30-40 11 p.

Research output: Contribution to journalArticle

Oryzias
Cardiac Myocytes
Epigenomics
Ventricular Myosins
Organ Size
3 Citations (Scopus)
Colonic Pseudo-Obstruction
Adrenal Gland Neoplasms
Megacolon
Adrenergic alpha-Antagonists
Receptors, Adrenergic, alpha
33 Citations (Scopus)

Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis

Uchida, K., Aramaki, M., Nakazawa, M., Yamagishi, C., Makino, S., Fukuda, K., Nakamura, T., Takahashi, T., Mikoshiba, K. & Yamagishi, H., 2010, In : PLoS One. 5, 9, p. 1-10 10 p., e12500.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Calcineurin
Genes
receptors
mice
87 Citations (Scopus)

Genome-wide association study of pancreatic cancer in Japanese population

Low, S. K., Kuchiba, A., Zembutsu, H., Saito, A., Takahashi, A., Kubo, M., Daigo, Y., Kamatani, N., Chiku, S., Totsuka, H., Ohnami, S., Hirose, H., Shimada, K., Okusaka, T., Yoshida, T., Nakamura, Y. & Sakamoto, H., 2010, In : PLoS One. 5, 7, e11824.

Research output: Contribution to journalArticle

pancreatic neoplasms
Genome-Wide Association Study
Pancreatic Neoplasms
Genes
Chromosomes
5 Citations (Scopus)

Identification of ADAMTS13 peptide sequences binding to von Willebrand factor

Moriki, T., Maruyama, I. N., Igari, A., Ikeda, Y. & Murata, M., 2010 Jan 1, In : Biochemical and Biophysical Research Communications. 391, 1, p. 783-788 6 p.

Research output: Contribution to journalArticle

von Willebrand Factor
Epitopes
Peptides
Screening
Bacteriophages
41 Citations (Scopus)

Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes

Kohno, T., Kunitoh, H., Shimada, Y., Shiraishi, K., Ishii, Y., Goto, K., Ohe, Y., Nishiwaki, Y., Kuchiba, A., Yamamoto, S., Hirose, H., Oka, A., Yanagitani, N., Saito, R., Inoko, H. & Yokota, J., 2010 Jan 8, In : Carcinogenesis. 31, 5, p. 834-841 8 p.

Research output: Contribution to journalArticle

HLA Antigens
Genotype
Alleles
Adenocarcinoma
Odds Ratio
16 Citations (Scopus)

Initial experience of transumbilical laparoendoscopic single-site surgery of partial adrenalectomy in patient with aldosterone-producing adenoma

Yuge, K., Miyajima, A., Hasegawa, M., Miyazaki, Y., Maeda, T., Takeda, T., Takeda, A., Miyashita, K., Kurihara, I., Shibata, H., Kikuchi, E. & Oya, M., 2010, In : BMC Urology. 10, 19.

Research output: Contribution to journalArticle

Adrenalectomy
Aldosterone
Adenoma
Umbilicus
Fibrin Tissue Adhesive
5 Citations (Scopus)

Lemon grass (Cymbopogon citratus) ameliorates murine spontaneous ileitis by decreasing lymphocyte recruitment to the inflamed intestine

Watanabe, C., Hokari, R., Komoto, S., Kurihara, C., Okada, Y., Matsunaga, H., Takebayashi, K., Kawaguchi, A., Nagao, S., Tsuzuki, Y., Yokoyama, H., Hibi, T. & Miura, S., 2010 Jul, In : Microcirculation. 17, 5, p. 321-332 12 p.

Research output: Contribution to journalArticle

Cymbopogon
Ileitis
Intestines
Lymphocytes
citral
25 Citations (Scopus)

NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor

Takeda, A., Shibata, H., Kurihara, I., Kobayashi, S., Yokota, K., Suda, N., Mitsuishi, Y., Jo, R., Kitagawa, H., Kato, S., Saruta, T. & Itoh, H., 2010 Mar 12, In : Journal of Biological Chemistry. 285, 11, p. 8084-8093 10 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Co-Repressor Proteins
Aldosterone
Yeast
Nuclear Receptor Coactivator 1
278 Citations (Scopus)

Nongenetic method for purifying stem cell-derived cardiomyocytes

Hattori, F., Chen, H., Yamashita, H., Tohyama, S., Satoh, Y. S., Yuasa, S., Li, W., Yamakawa, H., Tanaka, T., Onitsuka, T., Shimoji, K., Ohno, Y., Egashira, T., Kaneda, R., Murata, M., Hidaka, K., Morisaki, T., Sasaki, E., Suzuki, T., Sano, M. & 3 others, Makino, S., Oikawa, S. & Fukuda, K., 2010 Jan, In : Nature Methods. 7, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Stem cells
Cardiac Myocytes
Stem Cells
Callithrix
35 Citations (Scopus)

Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2

Hayashi, K., Sasamura, H., Ishiguro, K., Sakamaki, Y., Azegami, T. & Itoh, H., 2010 Jul, In : Kidney International. 78, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Angiotensin II
Angiotensin Receptor Antagonists
Therapeutics
Podocytes
69 Citations (Scopus)

Serum high-molecular-weight adiponectin as a marker for the evaluation and care of subjects with metabolic syndrome and related disorders

Hirose, H., Yamamoto, Y., Seino-Yoshihara, Y., Kawabe, H. & Saito, I., 2010, In : Journal of Atherosclerosis and Thrombosis. 17, 12, p. 1201-1211 11 p.

Research output: Contribution to journalArticle

Adiponectin
Molecular Weight
Molecular weight
Serum
Insulin Resistance
7 Citations (Scopus)

Serum lipid levels are positively associated with non-erosive reflux disease, but not with functional heartburn

Matsuzaki, J., Suzuki, H., Iwasaki, E., Yokoyama, H., Sugino, Y. & Hibi, T., 2010 Sep, In : Neurogastroenterology and Motility. 22, 9

Research output: Contribution to journalArticle

Heartburn
Gastroesophageal Reflux
Lipids
Serum
Esophagitis
1 Citation (Scopus)

Structural features of the NAD-dependent in situ retinoic acid supply system in esophageal mucosa

Yokoyama, H., Shiraishi-Yokoyama, H. & Hibi, T., 2010 Feb, In : Alcoholism: Clinical and Experimental Research. 34, SUPPL. 1

Research output: Contribution to journalArticle

Tretinoin
NAD
Rats
Esophagus
Aldehyde Dehydrogenase
8 Citations (Scopus)
Adiponectin
C-Reactive Protein
Insulin Resistance
Molecular Weight
Molecular weight
10 Citations (Scopus)

Use of home blood pressure monitoring and exercise, diet and medication compliance in Japan

Saito, I., Nomura, M., Hirose, H. & Kawabe, H., 2010 Jul, In : Clinical and Experimental Hypertension. 32, 4, p. 210-213 4 p.

Research output: Contribution to journalArticle

Ambulatory Blood Pressure Monitoring
Medication Adherence
Japan
Exercise
Diet
34 Citations (Scopus)

Zac1 is an essential transcription factor for cardiac morphogenesis

Yuasa, S., Onizuka, T., Shimoji, K., Ohno, Y., Kageyama, T., Yoon, S. H., Egashira, T., Seki, T., Hashimoto, H., Nishiyama, T., Kaneda, R., Murata, M., Hattori, F., Makino, S., Sano, M., Ogawa, S., Prall, O. W. J., Harvey, R. P. & Fukuda, K., 2010 Apr, In : Circulation Research. 106, 6, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

Morphogenesis
Transcription Factors
Gene Regulatory Networks
Atrial Natriuretic Factor
Zinc Fingers
2009
6 Citations (Scopus)
Langerhans Cell Histiocytosis
Hypothyroidism
Type 1 Diabetes Mellitus
Diabetes Mellitus
Thyroid Gland
1 Citation (Scopus)

A novel in vitro system for studying cardiomyocyte differentiation with medaka embryonic cells

Hyodo, M., Makino, S., Awaji, Y., Sakurada, Y., Ohkubo, T., Murata, M., Fukuda, K. & Tsuda, M., 2009, In : International Journal of Developmental Biology. 53, 4, p. 615-622 8 p.

Research output: Contribution to journalArticle

Oryzias
Cardiac Myocytes
Conditioned Culture Medium
Blastula
Inhibins
13 Citations (Scopus)

CD36 single nucleotide polymorphism is associated with variation in low-density lipoprotein-cholesterol in young Japanese men

Morii, T., Ohno, Y., Kato, N., Hirose, H., Kawabe, H., Hirao, K., Eguchi, T., Maruyama, T., Hayashi, M., Saito, I., Yazaki, Y. & Saruta, T., 2009 Jun, In : Biomarkers. 14, 4, p. 207-212 6 p.

Research output: Contribution to journalArticle

Polymorphism
LDL Cholesterol
Single Nucleotide Polymorphism
Nucleotides
Genes
2 Citations (Scopus)
Young Adult
Healthy Volunteers
15 Citations (Scopus)

Concentrations of clarithromycin and active metabolite in the epithelial lining fluid of patients with Mycobacterium avium complex pulmonary disease

Hasegawa, N., Nishimura, T., Watabnabe, M., Tasaka, S., Nakano, Y., Yamazaki, K., Hashimoto, S., Nishimura, M. & Ishizaka, A., 2009 Jun, In : Pulmonary Pharmacology and Therapeutics. 22, 3, p. 190-193 4 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Pulmonary diseases
Clarithromycin
Metabolites
Linings
85 Citations (Scopus)

Contribution of nicotine acetylcholine receptor polymorphisms to lung cancer risk in a smoking-independent manner in the Japanese

Shiraishi, K., Kohno, T., Kunitoh, H., Watanabe, S. I., Goto, K., Nishiwaki, Y., Shimada, Y., Hirose, H., Saito, I., Kuchiba, A., Yamamoto, S. & Yokota, J., 2009, In : Carcinogenesis. 30, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Nicotine
Lung Neoplasms
Smoking
Single Nucleotide Polymorphism
11 Citations (Scopus)

Determinants of exaggerated difference in morning and evening home blood pressure in Japanese normotensives

Kawabe, H. & Saito, I., 2009, In : Hypertension Research. 32, 11, p. 1028-1031 4 p.

Research output: Contribution to journalArticle

Blood Pressure
Odds Ratio
Confidence Intervals
Alcohol Drinking
Antihypertensive Agents
5 Citations (Scopus)
Angiotensin II Type 1 Receptor Blockers
Angiotensin Receptor Antagonists
Plasminogen Activator Inhibitor 1
Angiotensin-Converting Enzyme Inhibitors
Primary Health Care
19 Citations (Scopus)
Metabolome
Abdominal Obesity
Adiponectin
Molecular Weight
Molecular weight
11 Citations (Scopus)

FOXP3/Scurfin gene polymorphism is associated with adult onset type 1 diabetes in Japanese, especially in women and slowly progressive-type patients

Iwase, K., Shimada, A., Kawai, T., Okubo, Y., Kanazawa, Y., Irie, J., Oikawa, Y., Hirose, H., Maruyama, T. & Itoh, H., 2009, In : Autoimmunity. 42, 2, p. 159-167 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Genes
Genotype
Regulatory T-Lymphocytes
Age of Onset
55 Citations (Scopus)
Adiponectin
Molecular Weight
Population
Hypoglycemic Agents
Adipocytes
6 Citations (Scopus)

HMW-adiponectin associates with triglyceride concentrations in type 1 diabetic patients

Maruyama, C., Ishibashi, R., Araki, R., Koike, S., Hirose, H. & Maruyama, T., 2009, In : Journal of Atherosclerosis and Thrombosis. 16, 3, p. 207-216 10 p.

Research output: Contribution to journalArticle

Adiponectin
Triglycerides
Molecular Weight
Molecular weight
Bread
23 Citations (Scopus)

MCP-1 gene A-2518G polymorphism and carotid artery atherosclerosis in patients with type 2 diabetes

Yuasa, S., Maruyama, T., Yamamoto, Y., Hirose, H., Kawai, T., Matsunaga-Irie, S. & Itoh, H., 2009 Dec, In : Diabetes Research and Clinical Practice. 86, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Chemokine CCL2
Carotid Arteries
Type 2 Diabetes Mellitus
Genes
10 Citations (Scopus)

Molecular embryology for an understanding of congenital heart diseases

Yamagishi, H., Maeda, J., Uchida, K., Tsuchihashi, T., Nakazawa, M., Aramaki, M., Kodo, K. & Yamagishi, C., 2009, In : Anatomical Science International. 84, 3, p. 88-94 7 p.

Research output: Contribution to journalArticle

Embryology
Heart Diseases
Morphogenesis
Cardiovascular System
Mesoderm
17 Citations (Scopus)
Weights and Measures
Obesity
Japan
Body Weight
Sports
37 Citations (Scopus)

Omentopexy enhances graft function in myocardial cell sheet transplantation

Suzuki, R., Hattori, F., Itabashi, Y., Yoshioka, M., Yuasa, S., Manabe-Kawaguchi, H., Murata, M., Makino, S., Kokaji, K., Yozu, R. & Fukuda, K., 2009 Sep 18, In : Biochemical and Biophysical Research Communications. 387, 2, p. 353-359 7 p.

Research output: Contribution to journalArticle

Transplantation (surgical)
Cell Transplantation
Grafts
Blood
Transplants
5 Citations (Scopus)

Possible association of tumor necrosis factor receptor 2 gene polymorphism with severe hypertension using the extreme discordant phenotype design

Eguchi, T., Maruyama, T., Ohno, Y., Morii, T., Hirao, K., Hirose, H., Kawabe, H., Saito, I., Hayashi, M. & Saruta, T., 2009, In : Hypertension Research. 32, 9, p. 775-779 5 p.

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type II
Tumor Necrosis Factor Receptors
Hypertension
Phenotype
Insulin Resistance
38 Citations (Scopus)
Metabolites
C-Reactive Protein
Oxygen
Serum
Population
25 Citations (Scopus)

Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals

Omori, S., Tanaka, Y., Horikoshi, M., Takahashi, A., Hara, K., Hirose, H., Kashiwagi, A., Kaku, K., Kawamori, R., Kadowaki, T., Nakamura, Y. & Maeda, S., 2009 Aug, In : Diabetologia. 52, 8, p. 1554-1560 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Meta-Analysis
Single Nucleotide Polymorphism
Population
Genome-Wide Association Study
7 Citations (Scopus)

Reversible whole-organism cell cycle arrest in a living vertebrate

Sampetrean, O., Lida, S. I., Makino, S., Matsuzaki, Y., Ohno, K. & Saya, H., 2009 Feb 15, In : Cell Cycle. 8, 4, p. 620-627 8 p.

Research output: Contribution to journalArticle

Oryzias
Cell Cycle Checkpoints
Vertebrates
Cell Cycle
Acclimatization
13 Citations (Scopus)

Serodiagnostic contributions of antibody titers against mycobacterial lipid antigens in mycobacterium avium complex pulmonary disease

Nishimura, T., Hasegawa, N., Fujita, Y., Yano, I. & Ishizaka, A., 2009 Aug 15, In : Clinical Infectious Diseases. 49, 4, p. 529-535 7 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Lung Diseases
Lipids
Antigens
Antibodies
129 Citations (Scopus)

Serum bile acid along with plasma incretins and serum high-molecular weight adiponectin levels are increased after bariatric surgery

Nakatani, H., Kasama, K., Oshiro, T., Watanabe, M., Hirose, H. & Itoh, H., 2009 Oct, In : Metabolism: Clinical and Experimental. 58, 10, p. 1400-1407 8 p.

Research output: Contribution to journalArticle

Incretins
Bariatric Surgery
Adiponectin
Bile Acids and Salts
Molecular Weight
6 Citations (Scopus)

Significance of ALT/AST ratio for specifying subjects with metabolic syndrome in its silent stage

Ohgo, H., Yokoyama, H., Hirose, H., Kawabe, H., Saito, I., Tomita, K. & Hibi, T., 2009 Jan, In : Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 3, 1, p. 3-6 4 p.

Research output: Contribution to journalArticle

Aspartate Aminotransferases
Alanine Transaminase
Intra-Abdominal Fat
Waist Circumference
Liver Function Tests
31 Citations (Scopus)

Therapeutic effects of various initial combinations of chemotherapy including clarithromycin against Mycobacterium avium complex pulmonary disease

Hasegawa, N., Nishimura, T., Ohtani, S., Takeshita, K., Fukunaga, K., Tasaka, S., Urano, T., Ishii, K., Miyairi, M. & Ishizaka, A., 2009 Dec 1, In : Chest. 136, 6, p. 1569-1575 7 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Clarithromycin
Therapeutic Uses
Combination Drug Therapy
Lung Diseases
6 Citations (Scopus)

Transmission of specific genotype streptomycin resistant strains of Mycobacterium tuberculosis in the Tokyo metropolitan area in Japan

Ohkado, A., Murase, Y., Mori, M., Hasegawa, N., Otsuka, G., Nagamine, M., Maeda, H., Uchimura, K., Ohmori, M., Yamada, N., Maeda, S., Kato, S., Mori, T. & Ishikawa, N., 2009 Aug 26, In : BMC Infectious Diseases. 9, p. 138 1 p., 1471.

Research output: Contribution to journalArticle

Tokyo
Streptomycin
Mycobacterium tuberculosis
Japan
Genotype
10 Citations (Scopus)
Alcohols
Drinking
Adiponectin
Habits
Ethanol