Research Output 1987 2019

2006
71 Citations (Scopus)

Nerve growth factor is critical for cardiac sensory innervation and rescues neuropathy in diabetic hearts

Ieda, M., Kanazawa, H., Ieda, Y., Kimura, K., Matsumura, K., Tomita, Y., Yagi, T., Onizuka, T., Shimoji, K., Ogawa, S., Makino, S., Sano, M. & Fukuda, K., 2006 Nov, In : Circulation. 114, 22, p. 2351-2363 13 p.

Research output: Contribution to journalArticle

Diabetic Neuropathies
Nerve Growth Factor
Diabetes Mellitus
Myocardial Ischemia
Spinal Ganglia
1 Citation (Scopus)

Small cell lung cancer with Sjögren's syndrome and Lambert-Eaton myasthenic syndrome

Nishimura, T., Tasaka, S., Yamasawa, W., Hasegawa, N., Soejima, K., Sayama, K., Asano, K. & Ishizaka, A., 2006 Oct, In : Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 44, 10, p. 775-778 4 p.

Research output: Contribution to journalArticle

Lambert-Eaton Myasthenic Syndrome
Muscle Weakness
Small Cell Lung Carcinoma
Lower Extremity
Gait
60 Citations (Scopus)

Standardized centile curves of body mass index for Japanese children and adolescents based on the 1978-1981 national survey data

Inokuchi, M., Hasegawa, T., Anzo, M. & Matsuo, N., 2006 Jul 1, In : Annals of Human Biology. 33, 4, p. 444-453 10 p.

Research output: Contribution to journalArticle

national surveys
body mass index
Body Mass Index
international trade
Surveys and Questionnaires
1 Citation (Scopus)
Liver Mitochondrion
Superoxides
Oxidation-Reduction
Glutathione
Reactive Oxygen Species
2005
122 Citations (Scopus)

Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk

Sakiyama, T., Kohno, T., Mimaki, S., Ohta, T., Yanagitani, N., Sobue, T., Kunitoh, H., Saito, R., Shimizu, K., Hirama, C., Kimura, J., Maeno, G., Hirose, H., Eguchi, T., Saito, D., Ohki, M. & Yokota, J., 2005 May 1, In : International Journal of Cancer. 114, 5, p. 730-737 8 p.

Research output: Contribution to journalArticle

p53 Genes
Amino Acid Substitution
DNA Repair
Single Nucleotide Polymorphism
Lung Neoplasms
7 Citations (Scopus)

Cellular insulin resistance in Epstein-Barr virus-transformed lymphoblasts from young insulin-resistant Japanese men

Morii, T., Ohno, Y., Hirose, H., Kawabe, H., Ogata, T., Hirao, K., Eguchi, T., Maruyama, T., Kanno, Y., Hayashi, M., Saito, I. & Saruta, T., 2005 Mar, In : Metabolism: Clinical and Experimental. 54, 3, p. 370-375 6 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Insulin Resistance
Facilitative Glucose Transport Proteins
Insulin
Glucose
7 Citations (Scopus)

Cryptococcal meningitis in an immunocompetent child

Shinjo(H), M., Miyairi, I., Sakurai, M., Takahashi, M., Ariyasu, D., Nakayama, T., Tokumura, M., Yamashita, R., Sunakawa, K. & Takahashi, T., 2005 Aug, In : European Journal of Pediatrics. 164, 9, p. 596-597 2 p.

Research output: Contribution to journalArticle

Cryptococcal Meningitis
Cryptococcus
Cryptococcus neoformans
Fluconazole
Antifungal Agents
15 Citations (Scopus)

Factor XII Shizuoka, a novel mutation (Ala392Thr) identified and characterized in a patient with congenital coagulation factor XII deficiency

Oguchi, S., Ishii, K., Moriki, T., Takeshita, E., Murata, M., Ikeda, Y. & Watanabe, K., 2005, In : Thrombosis Research. 115, 3, p. 191-197 7 p.

Research output: Contribution to journalArticle

Factor XII Deficiency
Factor XII
Mutation
Antigens
Amino Acid Substitution
10 Citations (Scopus)

Genetic analysis of hereditary factor X deficiency in a French patient of Sri Lankan ancestry: In vitro expression study identified Gly366Ser substitution as the molecular basis of the dysfunctional factor X

Isshiki, I., Favier, R., Moriki, T., Uchida, T., Ishihara, H., Van Dreden, P., Murata, M. & Ikeda, Y., 2005 Jan, In : Blood Coagulation and Fibrinolysis. 16, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

Factor X Deficiency
Factor X
Exons
Russell's Viper
Viper Venoms
56 Citations (Scopus)

Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus

Maeda, S., Tsukada, S., Kanazawa, A., Sekine, A., Tsunoda, T., Koya, D., Maegawa, H., Kashiwagi, A., Babazono, T., Matsuda, M., Tanaka, Y., Fujioka, T., Hirose, H., Eguchi, T., Ohno, Y., Groves, C. J., Hattersley, A. T., Hitman, G. A., Walker, M., Kaku, K. & 6 others, Iwamoto, Y., Kawamori, R., Kikkawa, R., Kamatani, N., McCarthy, M. I. & Nakamura, Y., 2005 Aug, In : Journal of Human Genetics. 50, 6, p. 283-292 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Genes
Odds Ratio
Introns
Activating Transcription Factor 2
37 Citations (Scopus)

GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men

Ogawa, T., Hirose, H., Miyashita, K., Saito, I. & Saruta, T., 2005 Mar, In : Metabolism: Clinical and Experimental. 54, 3, p. 296-299 4 p.

Research output: Contribution to journalArticle

Insulin
Genes
Homozygote
Serum
Insulin Resistance
22 Citations (Scopus)

Influence of repeated measurement on one occasion, on successive days, and on workdays on home blood pressure values

Kawabe, H., Saito, I. & Saruta, T., 2005 Feb, In : Clinical and Experimental Hypertension. 27, 2-3, p. 215-222 8 p.

Research output: Contribution to journalArticle

Blood Pressure
Guidelines
Equipment and Supplies
4 Citations (Scopus)

Influences of mothers' dieting behaviors on their junior high school daughters

Hirokane, K., Tokumura, M., Nanri, S., Kimura, K. & Saito, I., 2005 Sep, In : Eating and Weight Disorders. 10, 3, p. 162-167 6 p.

Research output: Contribution to journalArticle

Diet
Feeding Behavior
Consciousness
Cooking
Eating
2 Citations (Scopus)
Life Style
Ethanol
Insulin
Insulin Resistance
Snacks
19 Citations (Scopus)
Gastric Mucosa
Tretinoin
Vitamin A
Alcohol Dehydrogenase
Protein Isoforms
32 Citations (Scopus)

Status of home blood pressure measured in morning and evening: Evaluation in normotensives and hypertensives in Japanese urban population

Kawabe, H., Saito, I. & Saruta, T., 2005 Jun, In : Hypertension Research. 28, 6, p. 491-498 8 p.

Research output: Contribution to journalArticle

Urban Population
Blood Pressure
40 Citations (Scopus)

Ubc9 and protein inhibitor of activated STAT 1 activate chicken ovalbumin upstream promoter-transcription factor I-mediated human CYP11B2 gene transcription

Kurihara, I., Shibata, H., Kobayashi, S., Suda, N., Ikeda, Y., Yokota, K., Takeda, A., Saito, I., Rainey, W. E. & Saruta, T., 2005 Feb 25, In : Journal of Biological Chemistry. 280, 8, p. 6721-6730 10 p.

Research output: Contribution to journalArticle

COUP Transcription Factor I
Protein Inhibitors of Activated STAT
Cytochrome P-450 CYP11B2
Transcription
Genes
14 Citations (Scopus)

Usefulness of QuantiFERON®TB-2G in contact investigation of a tuberculosis outbreak in a university

Funayama, K., Tsujimoto, A., Mori, M., Yamamoto, H., Fujiwara, K., Nishimura, T., Hasegawa, N., Horiguchi, I., Mori, T. & Marui, E., 2005 Jul, In : Kekkaku. 80, 7, p. 527-534 8 p.

Research output: Contribution to journalArticle

Tuberculin
Disease Outbreaks
Tuberculosis
Students
Erythema
2004
12 Citations (Scopus)

Acetaldehyde accumulation suppresses Kupffer cell release of TNF-α and modifies acute hepatic inflammation in rats

Nakamura, Y., Yokoyama, H., Higuchi, S., Hara, S., Kato, S. & Ishii, H., 2004 Feb, In : Journal of Gastroenterology. 39, 2, p. 140-147 8 p.

Research output: Contribution to journalArticle

Kupffer Cells
Acetaldehyde
Tumor Necrosis Factor-alpha
Disulfiram
Ethanol
171 Citations (Scopus)

Adiponectin, an Adipocyte-Derived Protein, Predicts Future Insulin Resistance: Two-Year Follow-Up Study in Japanese Population

Yamamoto, Y., Hirose, H., Saito, I., Nishikai, K. & Saruta, T., 2004 Jan, In : Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 87-90 4 p.

Research output: Contribution to journalArticle

Adiponectin
Adipocytes
Insulin Resistance
Insulin
Population
26 Citations (Scopus)

Associations among lifestyle status, serum adiponectin level and insulin resistance

Yokoyama, H., Hirose, H., Ohgo, H. & Saito, I., 2004 Jun, In : Internal Medicine. 43, 6, p. 453-457 5 p.

Research output: Contribution to journalArticle

Adiponectin
Insulin Resistance
Life Style
Serum
Radioimmunoassay
6 Citations (Scopus)
Leptin
Transaminases
Life Style
Serum
Ethanol
48 Citations (Scopus)

Autoimmune pancreatitis with pseudocysts

Nishimura, T., Masaoka, T., Suzuki, H., Aiura, K., Nagata, H. & Ishii, H., 2004 Oct, In : Journal of Gastroenterology. 39, 10, p. 1005-1010 6 p.

Research output: Contribution to journalArticle

Pancreatitis
Pancreas
Immunoglobulin G
Pancreatic Ducts
Back Pain
13 Citations (Scopus)

COUP-TF and transcriptional co-regulators in adrenal steroidogenesis

Shibata, H., Kobayashi, S., Kurihara, I., Suda, N., Yokota, K., Takeda, A., Ikeda, Y., Saito, I., Rainey, W. E. & Saruta, T., 2004, In : Endocrine Research. 30, 4, p. 795-801 7 p.

Research output: Contribution to journalArticle

COUP Transcription Factors
Steroidogenic Factor 1
Cytochrome P-450 CYP11B2
Steroid 17-alpha-Hydroxylase
Sumoylation
3 Citations (Scopus)

Effects of leptin receptor gene 3'-untranslated region polymorphism on metabolic profiles in young Japanese men.

Nishikai, K., Hirose, H., Ishii, T., Hayashi, M., Saito, I. & Saruta, T., 2004, In : Journal of Atherosclerosis and Thrombosis. 11, 2, p. 73-78 6 p.

Research output: Contribution to journalArticle

Leptin Receptors
Metabolome
3' Untranslated Regions
Polymorphism
HDL Cholesterol
39 Citations (Scopus)

FHL2, UBC9, and PIAS1 are novel estrogen receptor α-interacting proteins

Kobayashi, S., Shibata, H., Yokota, K., Suda, N., Takeda, A., Kurihara, I., Saito, I. & Saruta, T., 2004, In : Endocrine Research. 30, 4, p. 617-621 5 p.

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
Estrogen Receptors
Sumoylation
COS Cells
Estradiol
18 Citations (Scopus)

Genetic analyses and expression studies identified a novel mutation (W486C) as a molecular basis of congenital coagulation factor XII deficiency

Ishii, K., Oguchi, S., Moriki, T., Yatabe, Y., Takeshita, E., Murata, M., Ikeda, Y. & Watanabe, K., 2004 Jul, In : Blood Coagulation and Fibrinolysis. 15, 5, p. 367-373 7 p.

Research output: Contribution to journalArticle

Factor XII Deficiency
Factor XII
Mutation
Amino Acid Substitution
Antigens
7 Citations (Scopus)

Genetic testing of glycogen storage disease type Ib in Japan: Five novel G6PT1 mutations and a rapid detection method for a prevalent mutation W118R

Kojima, K., Kure, S., Kamada, F., Hao, K., Ichinohe, A., Sato, K., Aoki, Y., Yoichi, S., Kubota, M., Horikawa, R., Utsumi, A., Miura, M., Ogawa, S., Kanazawa, M., Kohno, Y., Inokuchi, M., Hasegawa, T., Narisawa, K. & Matsubara, Y., 2004 Apr, In : Molecular Genetics and Metabolism. 81, 4, p. 343-346 4 p.

Research output: Contribution to journalArticle

Glycogen Storage Disease
Genetic Testing
Glycogen
Japan
Mutation
6 Citations (Scopus)

Height-specific body mass index reference curves for Japanese children and adolescents 5-17 years of age

Tokumura, M., Nanri, S., Kimura, K., Tanaka, T. & Fujita, H., 2004 Oct, In : Pediatrics International. 46, 5, p. 525-530 6 p.

Research output: Contribution to journalArticle

Body Mass Index
Pediatric Obesity
Reference Values
School Health Services
Age Groups
8 Citations (Scopus)

Hyperinsulinemic hypoglycemia in a newborn infant with trisomy 13 [1]

Tamame, T., Hori, N., Homma, H., Yoshida, R., Inokuchi, M., Kosaki, K., Takahashi, T. & Hasegawa, T., 2004 Sep 1, In : American Journal of Medical Genetics. 129 A, 3, p. 321-322 2 p.

Research output: Contribution to journalArticle

Chromosome Disorders
Chromosomes, Human, Pair 13
Trisomy
Hyperinsulinism
Hypoglycemia
48 Citations (Scopus)

Inverse association between serum adiponectin level and transaminase activities in Japanese male workers

Yokoyama, H., Hirose, H., Ohgo, H. & Saito, I., 2004 Jul, In : Journal of Hepatology. 41, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

Adiponectin
Transaminases
Serum
Insulin Resistance
Metabolic Diseases
22 Citations (Scopus)

Kupffer cell depletion attenuates superoxide anion release into the hepatic sinusoids after lipopolysaccharicle treatment]

Fukuda, M., Yokoyama, H., Mizukami, T., Ohgo, H., Okamura, Y., Kamegaya, Y., Horie, Y., Kato, S. & Ishii, H., 2004, In : Journal of Gastroenterology and Hepatology (Australia). 19, 10, p. 1155-1162 8 p.

Research output: Contribution to journalArticle

Kupffer Cells
Superoxides
Liver
Endotoxemia
Lipopolysaccharides
21 Citations (Scopus)

Proteasome-mediated mineralocorticoid receptor degradation attenuates transcriptional response to aldosterone

Yokota, K., Shibata, H., Kobayashi, S., Suda, N., Takeda, A., Kurihara, I., Saito, I. & Saruta, T., 2004, In : Endocrine Research. 30, 4, p. 611-616 6 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Proteasome Endopeptidase Complex
Aldosterone
Ubiquitin
Estrogen Receptors
66 Citations (Scopus)

Relation between Development of Nephropathy and the p22phox C242T and Receptor for Advanced Glycation End Product G1704T Gene Polymorphisms in Type 2 Diabetic Patients

Matsunaga-Irie, S., Maruyama, T., Yamamoto, Y., Motohashi, Y., Hirose, H., Shimada, A., Murata, M. & Saruta, T., 2004 Feb, In : Diabetes Care. 27, 2, p. 303-307 5 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Genotype
Genes
NADP
Oxidative Stress
64 Citations (Scopus)

Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population

Ogawa, T., Hirose, H., Yamamoto, Y., Nishikai, K., Miyashita, K., Nakamura, H., Saito, I. & Saruta, T., 2004 Jul, In : Metabolism: Clinical and Experimental. 53, 7, p. 879-885 7 p.

Research output: Contribution to journalArticle

Leptin Receptors
Adiponectin
Leptin
Insulin Resistance
Lipids
77 Citations (Scopus)

The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: Possible physiological significance of specific cleavage by caspase 3

Nakayama, T., Hattori, M., Uchida, K., Nakamura, T., Tateishi, Y., Bannai, H., Iwai, M., Michikawa, T., Inoue, T. & Mikoshiba, K., 2004 Jan 15, In : Biochemical Journal. 377, 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Green Fluorescent Proteins
Caspase 3
Thapsigargin
Adenosine Triphosphate
2003
12 Citations (Scopus)
gamma-Glutamyltransferase
Guanosine Triphosphate
Insulin Resistance
Insulin
Alcohol Drinking
64 Citations (Scopus)

Combination therapy with PPARγ and PPARα agonists increases glucose-stimulated insulin secretion in db/db mice

Yajima, K., Hirose, H., Fujita, H., Seto, Y., Fujita, H., Ukeda, K., Miyashita, K., Kawai, T., Yamamoto, Y., Ogawa, T., Yamada, T. & Saruta, T., 2003 May 1, In : American Journal of Physiology - Endocrinology and Metabolism. 284, 5 47-5

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
pioglitazone
Insulin
Glucose
Bezafibrate
7 Citations (Scopus)

Correlation between insulin resistance and γ-glutamyl transpeptidase sensitivity in light drinkers

Moriya, S., Yokoyama, H., Hirose, H., Ishii, H. & Saito, I., 2003 Aug 1, In : Alcoholism: Clinical and Experimental Research. 27, 8 SUPPL.

Research output: Contribution to journalArticle

Photophobia
gamma-Glutamyltransferase
Insulin Resistance
Insulin
Ethanol
111 Citations (Scopus)

Critical regions for activation gating of the inositol 1,4,5-trisphosphate receptor

Uchida, K., Miyauchi, H., Furuichi, T., Michikawa, T. & Mikoshiba, K., 2003 May 9, In : Journal of Biological Chemistry. 278, 19, p. 16551-16560 10 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Chemical activation
Ligands
Inositol 1,4,5-Trisphosphate
Model structures
1 Citation (Scopus)

How to use anti-hypertensive medication in management of diabetic patients

Hirose, H. & Saito, I., 2003, In : Nippon rinsho. Japanese journal of clinical medicine. 61, 7, p. 1205-1209 5 p.

Research output: Contribution to journalArticle

Antihypertensive Agents
Hypertension
Insulin Resistance
Lipids
Angiotensin Receptor Antagonists
30 Citations (Scopus)

Insulin resistance and hypertension: Seven-year follow-up study in middle-aged Japanese men (the KEIO study)

Hirose, H., Saito, I., Kawabe, H. & Saruta, T., 2003 Oct, In : Hypertension Research. 26, 10, p. 795-800 6 p.

Research output: Contribution to journalArticle

Insulin Resistance
Blood Pressure
Hypertension
Body Mass Index
Fasting
22 Citations (Scopus)

No influence of the PPARγ2 pro12Ala genotype on serum adiponectin concentrations in healthy Europeans (multiple letters)

Thamer, C., Machicao, F., Fritsche, A., Stumvoll, M., Häring, H., Yamamoto, Y. & Hirose, H., 2003 Jun 1, In : Metabolism: Clinical and Experimental. 52, 6, p. 798-799 2 p.

Research output: Contribution to journalArticle

Adiponectin
Cytoplasmic and Nuclear Receptors
Osmolar Concentration
Intercellular Signaling Peptides and Proteins
Transcription Factors
26 Citations (Scopus)

Prescribed exercise training improves exercise capacity of convalescent children and adolescents with anorexia nervosa

Tokumura, M., Yoshiba, S., Tanaka, T., Nanri, S. & Watanabe, H., 2003 Jun 1, In : European Journal of Pediatrics. 162, 6, p. 430-431 2 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Relation between blood pressure and rhinitis in a Japanese adolescent population

Saito, I., Mori, M., Shibata, H., Hirose, H., Tsujioka, M. & Kawabe, H., 2003 Dec, In : Hypertension Research. 26, 12, p. 961-963 3 p.

Research output: Contribution to journalArticle

Rhinitis
Blood Pressure
Population
Allergic Rhinitis
Students
10 Citations (Scopus)

Relation between blood pressure control, body mass index, and intensity of medical treatment

Saito, I., Murata, K., Hirose, H., Tsujioka, M. & Kawabe, H., 2003 Sep 1, In : Hypertension Research. 26, 9, p. 711-715 5 p.

Research output: Contribution to journalArticle

Body Mass Index
Blood Pressure
Therapeutics
Pharmaceutical Preparations
Insulin Resistance
4 Citations (Scopus)

Stromal cell-derived factor-1 chemokine gene polymorphism is not associated with onset age of japanese type 1 diabetes

Shigihara, T., Shimada, A., Yamada, S., Maruyama, T., Hirose, H. & Saruta, T., 2003, In : Annals of the New York Academy of Sciences. 1005, p. 328-331 4 p.

Research output: Contribution to journalArticle

Chemokine CXCL12
Medical problems
Polymorphism
Type 1 Diabetes Mellitus
Age of Onset
5 Citations (Scopus)
Histamine Receptors
Tretinoin
Vitamin A
NAD
Esophagus
14 Citations (Scopus)

Trends in blood pressure control in hypertensive patients with diabetes mellitus in Japan

Hirose, H. & Saito, I., 2003 Sep 1, In : Hypertension Research. 26, 9, p. 717-722 6 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Japan
Guidelines
Blood Pressure
Calcium Channel Blockers
81 Citations (Scopus)

Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes

Motohashi, Y., Yamada, S., Yanagawa, T., Maruyama, T., Suzuki, R., Niino, M., Fukazawa, T., Kasuga, A., Hirose, H., Matsubara, K., Shimada, A. & Saruta, T., 2003 Jul 1, In : Journal of Clinical Endocrinology and Metabolism. 88, 7, p. 3137-3140 4 p.

Research output: Contribution to journalArticle

Calcitriol Receptors
Medical problems
Polymorphism
Type 1 Diabetes Mellitus
Genes