Research Output per year
Research Output
2020
Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: A case report
Hongo, H., Kosaka, T., Aimono, E., Nishihara, H. & Oya, M., 2020 Jan 13, In : Diagnostic Pathology. 15, 1, 5.Research output: Contribution to journal › Article
Open Access
Cancer gene profiling explores the possible precision medicine for diffuse-type gastric adenocarcinoma
Ishikawa, M., Hayashi, H., Sakamoto, N., Tanaka, S. & Nishihara, H., 2020 Jan 1, In : Medical Oncology. 37, 1, 10.Research output: Contribution to journal › Article
Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival
Yokouchi, H., Nishihara, H., Harada, T., Yamazaki, S., Kikuchi, H., Oizumi, S., Uramoto, H., Tanaka, F., Harada, M., Akie, K., Sugaya, F., Fujita, Y., Takamura, K., Kojima, T., Higuchi, M., Honjo, O., Minami, Y., Watanabe, N., Nishimura, M., Suzuki, H. & 2 others, , 2020 Jul, In : Heliyon. 6, 7, e04439.Research output: Contribution to journal › Article
Open Access
Establishment and characterization of a new malignant peritoneal mesothelioma cell line, KOG-1, from the ascitic fluid of a patient with pemetrexed chemotherapy resistance
Akahane, T., Hirasawa, A., Imoto, I., Okubo, A., Itoh, M., Nanki, Y., Yoshihama, T., Tominaga, E. & Aoki, D., 2020 Jan 1, In : Human Cell. 33, 1, p. 272-282 11 p.Research output: Contribution to journal › Article
Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation
Hiromi, T., Yokoyama, U., Kurotaki, D., Mamun, A., Ishiwata, R., Ichikawa, Y., Nishihara, H., Umemura, M., Fujita, T., Yasuda, S., Minami, T., Goda, M., Uchida, K., Suzuki, S., Takeuchi, I., Masuda, M., Breyer, R. M., Tamura, T. & Ishikawa, Y., 2020, (Accepted/In press) In : Arteriosclerosis, Thrombosis, and Vascular Biology. p. 1559-1573 15 p.Research output: Contribution to journal › Article
Open Access
Gefitinib alone versus gefitinib plus chemotherapy for non–small-cell lung cancer with mutated epidermal growth factor receptor: NEJ009 study
North-East Japan Study Group, 2020, In : Journal of Clinical Oncology. 38, 2, p. 115-123 9 p.Research output: Contribution to journal › Article
Genetic profiling of patients with adenoid cystic carcinoma of the Bartholin's glands reveals potential new routes for targeted therapies: A case report
Nakamura, K., Aimono, E., Tanishima, S., Nomura, H., Imai, M., Hayashi, H. & Nishihara, H., 2020 May 28, In : Diagnostic Pathology. 15, 1, 64.Research output: Contribution to journal › Article
Open Access
Intratumoral genomic heterogeneity may hinder precision medicine strategies in patients with serous ovarian carcinoma
Nakamura, K., Aimono, E., Tanishima, S., Imai, M., Nagatsuma, A. K., Hayashi, H., Yoshimura, Y., Nakayama, K., Kyo, S. & Nishihara, H., 2020 Apr, In : Diagnostics. 10, 4, 200.Research output: Contribution to journal › Article
Open Access
Japan society of clinical oncology/Japanese society of medical oncology-led clinical recommendations on the diagnosis and use of tropomyosin receptor kinase inhibitors in adult and pediatric patients with neurotrophic receptor tyrosine kinase fusion-positive advanced solid tumors, cooperated by the Japanese society of pediatric hematology/oncology
Naito, Y., Mishima, S., Akagi, K., Igarashi, A., Ikeda, M., Okano, S., Kato, S., Takano, T., Tsuchihara, K., Terashima, K., Nishihara, H., Nishiyama, H., Hiyama, E., Hirasawa, A., Hosoi, H., Maeda, O., Yatabe, Y., Okamoto, W., Ono, S., Kajiyama, H. & 6 others, , 2020 Mar 1, In : International Journal of Clinical Oncology. 25, 3, p. 403-417 15 p.Research output: Contribution to journal › Article
Open Access
Japan Society of Clinical Oncology provisional clinical opinion for the diagnosis and use of immunotherapy in patients with deficient DNA mismatch repair tumors, cooperated by Japanese Society of Medical Oncology, First Edition
Mishima, S., Taniguchi, H., Akagi, K., Baba, E., Fujiwara, Y., Hirasawa, A., Ikeda, M., Maeda, O., Muro, K., Nishihara, H., Nishiyama, H., Takano, T., Tsuchihara, K., Yatabe, Y., Kodera, Y. & Yoshino, T., 2020 Feb 1, In : International Journal of Clinical Oncology. 25, 2, p. 217-239 23 p.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
Key prognostic factors for EGFR-mutated non-adenocarcinoma lung cancer patients in the Japanese Joint Committee of Lung Cancer Registry Database
Kobayashi, K., Soejima, K., Fukunaga, K., Shintani, Y., Sekine, I., Shukuya, T., Takayama, K., Inoue, A., Okamoto, I., Kiura, K., Takahashi, K., Yamamoto, N., Takiguchi, Y., Miyaoka, E., Okumura, M. & Yoshino, I., 2020 Aug, In : Lung Cancer. 146, p. 236-243 8 p.Research output: Contribution to journal › Article
Kimura Disease Presenting with Buccal Mass: A Case Report and Literature Review
Sato, R., Bandoh, N., Goto, T., Ichikawa, H., Uemura, A., Suzuki, S., Yamaguchi, T., Aimono, E., Nishihara, H., Katada, A. & Harabuchi, Y., 2020, (Accepted/In press) In : Head and Neck Pathology.Research output: Contribution to journal › Article
Next-generation sequencing in residual liquid-based cytology specimens for cancer genome analysis
Yamaguchi, T., Akahane, T., Harada, O., Kato, Y., Aimono, E., Takei, H., Tasaki, T., Noguchi, H., Nishihara, H., Kamata, H. & Tanimoto, A., 2020, (Accepted/In press) In : Diagnostic Cytopathology.Research output: Contribution to journal › Article
Osimertinib Overcomes Alectinib Resistance Caused by Amphiregulin in a Leptomeningeal Carcinomatosis Model of ALK-Rearranged Lung Cancer
Arai, S., Takeuchi, S., Fukuda, K., Taniguchi, H., Nishiyama, A., Tanimoto, A., Satouchi, M., Yamashita, K., Ohtsubo, K., Nanjo, S., Kumagai, T., Katayama, R., Nishio, M., Zheng, M. M., Wu, Y. L., Nishihara, H., Yamamoto, T., Nakada, M. & Yano, S., 2020 May, In : Journal of Thoracic Oncology. 15, 5, p. 752-765 14 p.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
Resection of a desmoid-type fibromatosis with a CTNNB1 p.S45P mutation using a cervico-thoracic approach: A case report and literature review
Sato, R., Bandoh, N., Goto, T., Uemura, A., Inoue, N., Otomo, Y., Nakano, H., Yamaguchi, T., Kato, Y., Nishihara, H., Takei, H. & Harabuchi, Y., 2020, (Accepted/In press) In : Auris Nasus Larynx.Research output: Contribution to journal › Article
Successful Retreatment Using Pembrolizumab for Non–small-cell Lung Cancer After Severe Immune-related Hepatitis: A Case Report
Kobayashi, K., Nakachi, I., Mitsuishi, A., Arai, D., Sakurai, K., Masaki, K., Chiyotani, A., Takahashi, H., Tahara, T. & Soejima, K., 2020 Jan, In : Clinical Lung Cancer. 21, 1, p. e30-e32Research output: Contribution to journal › Article
The NOTCH–FOXM1 axis plays a key role in mitochondrial biogenesis in the induction of human stem cell memory–like CAR-T cells
Kondo, T., Ando, M., Nagai, N., Tomisato, W., Srirat, T., Liu, B., Mise-Omata, S., Ikeda, M., Chikuma, S., Nishimasu, H., Nureki, O., Ohmura, M., Hayakawa, N., Hishiki, T., Uchibori, R., Ozawa, K. & Yoshimura, A., 2020 Feb 1, In : Cancer Research. 80, 3, p. 471-483 13 p.Research output: Contribution to journal › Article
2
Citations
(Scopus)
がんゲノム医療における患者対応の経験から
Research output: Contribution to journal › Article
Open Access
ゲノム医療に求められるシステム構築と人材について
Research output: Contribution to journal › Article
Open Access
2019
A first Japanese case of neuroendocrine prostate cancer accompanied by lung and brain metastasis with somatic and germline BRCA2 mutation
Kosaka, T., Hongo, H., Aimono, E., Matsumoto, K., Hayashida, T., Mikami, S., Nishihara, H. & Oya, M., 2019 Dec 1, In : Pathology international. 69, 12, p. 715-720 6 p.Research output: Contribution to journal › Article
Open Access
Analysis of DLL3 and ASCL1 in Surgically Resected Small Cell Lung Cancer (HOT1702)
on behalf of Hokkaido Lung Cancer Clinical Study Group, 2019 Nov 1, In : Oncologist. 24, 11, p. e1172-e1179Research output: Contribution to journal › Article
3
Citations
(Scopus)
A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients
Tani, T., Naoki, K., Yasuda, H., Arai, D., Ishioka, K., Ohgino, K., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T. & Soejima, K., 2019 Nov 1, In : Cancer Chemotherapy and Pharmacology. 84, 5, p. 1065-1071 7 p.Research output: Contribution to journal › Article
2
Citations
(Scopus)
Brain metastases in oncogene-driven non-small cell lung cancer
Nishino, M., Soejima, K. & Mitsudomi, T., 2019 Jan 1, In : Translational Lung Cancer Research. 8, p. S298-S307Research output: Contribution to journal › Review article
Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis
Akahane, T., Yamaguchi, T., Kato, Y., Yokoyama, S., Hamada, T., Nishida, Y., Higashi, M., Nishihara, H., Suzuki, S., Ueno, S. & Tanimoto, A., 2019 Jun, In : PloS one. 14, 6, e0217724.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
Effectiveness of a genetic test panel designed for gynecological cancer: an exploratory study
Ida, K., Miyamoto, T., Higuchi, S., Takeuchi, H., Yamada, S., Ono, M., Nishihara, H. & Shiozawa, T., 2019 Jul 1, In : Medical Oncology. 36, 7, 62.Research output: Contribution to journal › Article
1
Citation
(Scopus)
Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts
Hegab, A. E., Ozaki, M., Kameyama, N., Gao, J., Kagawa, S., Yasuda, H., Soejima, K., Yin, Y., Guzy, R. D., Nakamura, Y., Ornitz, D. M. & Betsuyaku, T., 2019 Oct 1, In : Journal of Pathology. 249, 2, p. 193-205 13 p.Research output: Contribution to journal › Article
3
Citations
(Scopus)
Efficacy of afatinib or osimertinib plus cetuximab combination therapy for non-small-cell lung cancer with EGFR exon 20 insertion mutations
Hasegawa, H., Yasuda, H., Hamamoto, J., Masuzawa, K., Tani, T., Nukaga, S., Hirano, T., Kobayashi, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Lung Cancer. 127, p. 146-152 7 p.Research output: Contribution to journal › Article
9
Citations
(Scopus)
Epithelial-to-mesenchymal transition is a mechanism of ALK inhibitor resistance in lung cancer independent of ALK mutation status
Fukuda, K., Takeuchi, S., Arai, S., Katayama, R., Nanjo, S., Tanimoto, A., Nishiyama, A., Nakagawa, T., Taniguchi, H., Suzuki, T., Yamada, T., Nishihara, H., Ninomiya, H., Ishikawa, Y., Baba, S., Takeuchi, K., Horiike, A., Yanagitani, N., Nishio, M. & Yano, S., 2019 Apr 1, In : Cancer Research. 79, 7, p. 1658-1670 13 p.Research output: Contribution to journal › Article
16
Citations
(Scopus)
Establishment of permutation for cancer risk estimation in the urothelium based on genome-wide DNA methylation analysis
Tsumura, K., Arai, E., Tian, Y., Shibuya, A., Nishihara, H., Yotani, T., Yamada, Y., Takahashi, Y., Maeshima, A. M., Fujimoto, H., Nakagawa, T., Kume, H., Homma, Y., Yoshida, T. & Kanai, Y., 2019 Nov 25, In : Carcinogenesis. 40, 11, p. 1308-1319 12 p.Research output: Contribution to journal › Article
1
Citation
(Scopus)
Japanese Case of Enzalutamide-Resistant Prostate Cancer Harboring a SPOP Mutation With Scattered Allelic Imbalance: Response to Platinum-Based Therapy
Watanabe, K., Kosaka, T., Aimono, E., Hongo, H., Mikami, S., Nishihara, H. & Oya, M., 2019 Oct, In : Clinical Genitourinary Cancer. 17, 5, p. e897-e902Research output: Contribution to journal › Article
1
Citation
(Scopus)
Long-lasting response to nivolumab for a patient with lynch syndrome-associated lung adenocarcinoma
Masuzawa, K., Asakura, T., Ikemura, S., Yasuda, H., Kawada, I., Takaoka, S., Hayashi, Y., Nakajima, T., Arai, M., Fukunaga, K. & Soejima, K., 2019, In : JCO Precision Oncology. 3, p. 74-78 5 p.Research output: Contribution to journal › Article
Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations
Ikemura, S., Yasuda, H., Matsumoto, S., Kamada, M., Hamamoto, J., Masuzawa, K., Kobayashi, K., Manabe, T., Arai, D., Nakachi, I., Kawada, I., Ishioka, K., Nakamura, M., Namkoong, H., Naoki, K., Ono, F., Araki, M., Kanada, R., Ma, B., Hayashi, Y. & 8 others, , 2019 May 14, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10025-10030 6 p.Research output: Contribution to journal › Article
Open Access
7
Citations
(Scopus)
Monomer preference of EGFR tyrosine kinase inhibitors influences the synergistic efficacy of combination therapy with cetuximab
Oashi, A., Yasuda, H., Kobayashi, K., Tani, T., Hamamoto, J., Masuzawa, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Molecular cancer therapeutics. 18, 9, p. 1593-1601 9 p.Research output: Contribution to journal › Article
1
Citation
(Scopus)
Multicenter study of zoledronic acid administration in non-small-cell lung cancer patients with bone metastasis: Thoracic oncology research group (TORG) 1017
Nakahara, Y., Hosomi, Y., Shibuya, M., Mitsufuji, H., Katagiri, M., Naoki, K., Soejima, K., Nogami, N., Nagase, S., Nishikawa, M., Minato, K., Takiguchi, Y., Seki, N., Yamada, K., Seto, T. & Okamoto, H., 2019 Oct, In : Molecular and Clinical Oncology. 11, 4, p. 349-353 5 p.Research output: Contribution to journal › Article
Olaparib monotherapy for BRIP1-mutated high-grade serous endometrial cancer
Nakamura, K., Aimono, E., Tanishima, S., Imai, M., Nagatsuma, A. K., Hayashi, H., Yoshimura, Y., Nakayama, K., Kyo, S. & Nishihara, H., 2019 Jan 1, In : JCO Precision Oncology. 3, p. 283-290 8 p.Research output: Contribution to journal › Article
Open Access
Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness
Tanaka, H. Y., Kitahara, K., Sasaki, N., Nakao, N., Sato, K., Narita, H., Shimoda, H., Matsusaki, M., Nishihara, H., Masamune, A. & Kano, M. R., 2019 Feb, In : Biomaterials. 192, p. 355-367 13 p.Research output: Contribution to journal › Article
9
Citations
(Scopus)
Pathways of Progression From Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features
Omori, Y., Ono, Y., Tanino, M., Karasaki, H., Yamaguchi, H., Furukawa, T., Enomoto, K., Ueda, J., Sumi, A., Katayama, J., Muraki, M., Taniue, K., Takahashi, K., Ambo, Y., Shinohara, T., Nishihara, H., Sasajima, J., Maguchi, H., Mizukami, Y., Okumura, T. & 1 others, , 2019 Feb, In : Gastroenterology. 156, 3, p. 647-661.e2Research output: Contribution to journal › Article
Open Access
25
Citations
(Scopus)
Practical procedures for the integrated diagnosis of astrocytic and oligodendroglial tumors
The committee for molecular diagnosis of the Japan Society of Brain Tumor Pathology, 2019 Apr 25, In : Brain tumor pathology. 36, 2, p. 56-62 7 p.Research output: Contribution to journal › Article
2
Citations
(Scopus)
Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides
Fujii, K., Kubo, A., Miyashita, K., Sato, M., Hagiwara, A., Inoue, H., Ryuzaki, M., Tamaki, M., Hishiki, T., Hayakawa, N., Kabe, Y., Itoh, H. & Suematsu, M., 2019 Nov 14, In : JCI Insight. 4, 22, e124816.Research output: Contribution to journal › Article
Open Access
1
Citation
(Scopus)
2018
Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica
Nurkanto, A., Jeelani, G., Yamamoto, T., Hishiki, T., Naito, Y., Suematsu, M., Hashimoto, T. & Nozaki, T., 2018 Nov 30, In : Frontiers in Microbiology. 9, NOV, 2902.Research output: Contribution to journal › Article
2
Citations
(Scopus)
Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target
Nurkanto, A., Jeelani, G., Yamamoto, T., Naito, Y., Hishiki, T., Mori, M., Suematsu, M., Shiomi, K., Hashimoto, T. & Nozaki, T., 2018 Apr, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 1, p. 125-136 12 p.Research output: Contribution to journal › Article
3
Citations
(Scopus)
Characterization of centriole duplication in human epidermis, Bowen's disease, and squamous cell carcinoma
Watanuki, S., Fujita, H., Koyama, K., Amagai, M. & Kubo, A., 2018 Jan 1, (Accepted/In press) In : Journal of Dermatological Science.Research output: Contribution to journal › Article
1
Citation
(Scopus)
Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer
Kobayashi, K., Naoki, K., Manabe, T., Masuzawa, K., Hasegawa, H., Yasuda, H., Kawada, I., Soejima, K. & Betsuyaku, T., 2018 Jun 6, In : OncoTargets and Therapy. 11, p. 3335-3343 9 p.Research output: Contribution to journal › Article
10
Citations
(Scopus)
Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera
Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 Oct, In : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.Research output: Contribution to journal › Article
11
Citations
(Scopus)
Effectiveness of indocyanine green fluorescence in endoscopic marking in gastric cancer surgery: A feasibility study for replacing India ink
Ono, H., Kusano, M., Nihei, M., Hayashi, H., Fukushima, H., Kawakami, M., Danjo, Y., Nagashima, K., Shimizu, Y., Kawamata, F., Honda, S., Shimamura, T. & Nishihara, H., 2018, In : Journal of Japanese Society of Gastroenterology. 115, 4, p. 385-393 9 p.Research output: Contribution to journal › Article
Egfr-mutant non-small cell lung cancer accompanied by transient asymptomatic pulmonary opacities successfully treated with “stop-and-go” osimertinib
Kobayashi, K., Naoki, K., Kuroda, A., Yasuda, H., Kawada, I., Soejima, K. & Betsuyaku, T., 2018 Jan 1, In : Internal Medicine. 57, 7, p. 1007-1010 4 p.Research output: Contribution to journal › Article
Genetic mutation analysis of the malignant transformation of sinonasal inverted papilloma by targeted amplicon sequencing
Yasukawa, S., Kano, S., Hatakeyama, H., Nakamaru, Y., Takagi, D., Mizumachi, T., Suzuki, M., Suzuki, T., Nakazono, A., Tanaka, S., Nishihara, H. & Homma, A., 2018 Oct 1, In : International Journal of Clinical Oncology. 23, 5, p. 835-843 9 p.Research output: Contribution to journal › Article
4
Citations
(Scopus)
Genomic testing for pancreatic cancer in clinical practice as real-world evidence
Hayashi, H., Tanishima, S., Fujii, K., Mori, R., Okamura, Y., Yanagita, E., Matsuoka, R., Amano, T., Kinoshita, I., Komatsu, Y., Dosaka-Akita, H. & Nishihara, H., 2018 Sep, In : Pancreatology. 18, 6, p. 647-654 8 p.Research output: Contribution to journal › Article
8
Citations
(Scopus)
Glomangiopericytoma of the Nasal Cavity with CTNNB1 p.S37C Mutation: A Case Report and Literature Review
Kono, M., Bandoh, N., Matsuoka, R., Goto, T., Akahane, T., Kato, Y., Nakano, H., Yamaguchi, T., Harabuchi, Y. & Nishihara, H., 2018 Jan 1, (Accepted/In press) In : Head and Neck Pathology.Research output: Contribution to journal › Article
Open Access
3
Citations
(Scopus)
Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: Evidence from fatty acid-binding protein-4 and-5 knockout mice
Umbarawan, Y., Syamsunarno, M. R. A. A., Koitabashi, N., Yamaguchi, A., Hanaoka, H., Hishiki, T., Nagahata-Naito, Y., Obinata, H., Sano, M., Sunaga, H., Matsui, H., Tsushima, Y., Suematsu, M., Kurabayashi, M. & Iso, T., 2018 Jul 1, In : Cardiovascular Research. 114, 8, p. 1132-1144 13 p.Research output: Contribution to journal › Article
6
Citations
(Scopus)