Department of Clinical Medicine

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2020

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Mizuno, S., Ono, K., Mikami, Y., Naganuma, M., Fukuda, T., Minami, K., Masaoka, T., Terada, S., Yoshida, T., Saigusa, K., Hirahara, N., Miyata, H., Suda, W., Hattori, M. & Kanai, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

Open Access

A 3-Year Overall Survival Update From a Phase 2 Study of Chemoselection With DCF and Subsequent Conversion Surgery for Locally Advanced Unresectable Esophageal Cancer

Yokota, T., Kato, K., Hamamoto, Y., Tsubosa, Y., Ogawa, H., Ito, Y., Hara, H., Ura, T., Kojima, T., Chin, K., Hironaka, S., Kii, T., Kojima, Y., Akutsu, Y., Matsushita, H., Kawakami, K., Mori, K., Makiuchi, T., Nagumo, R. & Kitagawa, Y., 2020 Feb 1, In : Annals of Surgical Oncology. 27, 2, p. 460-467 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Aberrant expression of Wnt/β-catenin signaling pathway genes in aggressive malignant gastric gastrointestinal stromal tumors

Fujiya, K., Ohshima, K., Kitagawa, Y., Hatakeyama, K., Nagashima, T., Aizawa, D., Sugino, T., Urakami, K., Yamaguchi, K. & Terashima, M., 2020 Jan 1, (Accepted/In press) In : European Journal of Surgical Oncology.

Research output: Contribution to journalArticle

A Case of Esophageal Xanthoma with Epithelial Reactive Inflammation with a Characteristic Finding of Narrow-Band Imaging Magnifying Endoscopy

Mori, H., Kato, M. & Uraoka, T., 2020 Jan 1, In : Digestive Diseases. 38, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

A case of intrahepatic cholangiocellular carcinoma due to thorotrast deposition, well-controlled by radiofrequency ablation therapy

Taniki, N., Nakamoto, N., Yoshida, A., Chu, P. S., Ikura, A., Yamataka, K., Morikawa, R., Shiba, S., Yamaguchi, A., Usui, S., Ojiro, K., Ebinuma, H., Saito, H., Kubota, N., Masugi, Y., Sakamto, M. & Kanai, T., 2020 Jan 1, In : Acta Hepatologica Japonica. 61, 5, p. 262-269 8 p.

Research output: Contribution to journalArticle

Open Access

A case of pancreatic hamartoma with characteristic radiological findings: radiological-pathological correlation

Toyama, K., Matsusaka, Y., Okuda, S., Miura, E., Kubota, N., Masugi, Y., Kitago, M., Hori, S., Yokose, T., Shinoda, M., Sakamoto, M. & Jinzaki, M., 2020 Jul 1, In : Abdominal Radiology. 45, 7, p. 2244-2248 5 p.

Research output: Contribution to journalArticle

A case of spindle cell/pleomorphic lipoma on inferior border of the mandible

Munakata, K., Asoda, S., Usuda, S., Miyashita, H., Soma, T., Hasegawa, T., Ogawa, C., Ohyama, S., Yamauchi, T., Kawaida, M., Kameyama, K., Nakagawa, T. & Kawana, H., 2020 Jan, In : Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 32, 1, p. 49-52 4 p.

Research output: Contribution to journalArticle

Open Access

Accelerated Versus Standard Corneal Cross-Linking for Progressive Keratoconus: A Meta-Analysis of Randomized Controlled Trials

Kobashi, H. & Tsubota, K., 2020 Feb 1, In : Cornea. 39, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Achieving the Lowest Effective Antipsychotic Dose for Patients with Remitted Psychosis: A Proposed Guided Dose-Reduction Algorithm

Liu, C. C. & Takeuchi, H., 2020 Feb 1, In : CNS Drugs. 34, 2, p. 117-126 10 p.

Research output: Contribution to journalArticle

A Comparative Study Between Traditional Microscopic Surgeries and Endoscopic Endonasal Surgery for Skull Base Chordomas

Yumiko Oishi, O., Tamura, R., Takahashi, S., Morimoto, Y., Sato, M., Horikoshi, T., Hassaan, S., Yoshida, K. & Toda, M., 2020 Feb, In : World neurosurgery. 134, p. e1099-e1107

Research output: Contribution to journalArticle

Activation of extracellular signal-regulated kinase is associated with hepatocellular carcinoma with aggressive phenotypes

Minagawa, T., Yamazaki, K., Masugi, Y., Tsujikawa, H., Ojima, H., Hibi, T., Abe, Y., Yagi, H., Kitago, M., Shinoda, M., Itano, O., Kitagawa, Y. & Sakamoto, M., 2020 Mar 1, In : Hepatology Research. 50, 3, p. 353-364 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Acute blocking of forearm supination secondary to tearing of the triangular fibrocartilage complex

Suzuki, T., Nakamura, T., Tanino, Y., Obara, Y., Yoshikawa, Y. & Iwamoto, T., 2020 Jan 1, (Accepted/In press) In : Journal of Hand Surgery: European Volume.

Research output: Contribution to journalArticle

ADAM10 is indispensable for longitudinal bone growth in mice

Mizuno, S., Yoda, M., Kimura, T., Shimoda, M., Akiyama, H., Chiba, K., Nakamura, M. & Horiuchi, K., 2020 May, In : Bone. 134, 115273.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice

Suzuki, S., Ishii, M., Asakura, T., Namkoong, H., Okamori, S., Yagi, K., Kamata, H., Kusumoto, T., Kagawa, S., Hegab, A. E., Yoda, M., Horiuchi, K., Hasegawa, N. & Betsuyaku, T., 2020 Jun, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 6, p. L1172-L1182

Research output: Contribution to journalArticle

Adherence to antihypertensive medication and its predictors among non-elderly adults in Japan

Nishimura, S., Kumamaru, H., Shoji, S., Sawano, M., Kohsaka, S. & Miyata, H., 2020 Jul 1, In : Hypertension Research. 43, 7, p. 705-714 10 p.

Research output: Contribution to journalArticle

Adherence to the guidelines and the pathological diagnosis of high-risk gastrointestinal stromal tumors in the real world

The members of the STAR ReGISTry Study Group, 2020 Jan 1, In : Gastric Cancer. 23, 1, p. 118-125 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Adrenal cortex hypoxia modulates aldosterone production in heart failure

Yamashita, K., Ito, K., Endo, J., Matsuhashi, T., Katsumata, Y., Yamamoto, T., Shirakawa, K., Isobe, S., Kataoka, M., Yoshida, N., Goto, S., Moriyama, H., Kitakata, H., Mitani, F., Fukuda, K., Goda, N., Ichihara, A. & Sano, M., 2020 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Open Access

Age is a determining factor of dry eye-related signs and symptoms

Ayaki, M., Negishi, K., Kawashima, M., Uchino, M., Kaido, M. & Tsubota, K., 2020 Jan 1, In : Diagnostics. 10, 4, 193.

Research output: Contribution to journalArticle

Open Access

Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: A case report

Hongo, H., Kosaka, T., Aimono, E., Nishihara, H. & Oya, M., 2020 Jan 13, In : Diagnostic Pathology. 15, 1, 5.

Research output: Contribution to journalArticle

Open Access

Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia conducted in Japan during the past quarter century

Yanada, M., Takami, A., Yamasaki, S., Arai, Y., Konuma, T., Uchida, N., Najima, Y., Fukuda, T., Tanaka, M., Ozawa, Y., Ikegame, K., Takanashi, M., Ichinohe, T., Okamoto, S., Atsuta, Y. & Yano, S., 2020 Jun 1, In : Annals of Hematology. 99, 6, p. 1351-1360 10 p.

Research output: Contribution to journalArticle

Analysis of 122 triplet and one quadruplet pregnancies after single embryo transfer in Japan

Yamashita, S., Ikemoto, Y., Ochiai, A., Yamada, S., Kato, K., Ohno, M., Segawa, T., Nakaoka, Y., Toya, M., Kawachiya, S., Sato, Y., Takahashi, T., Takeuchi, S., Nomiyama, M., Tabata, C., Fujiwara, T., Okamoto, S., Kawamura, T., Kawagoe, J., Yamada, M. & 4 others, Sato, Y., Marumo, G., Sugiyama, R. & Kuroda, K., 2020 Mar, In : Reproductive BioMedicine Online. 40, 3, p. 374-380 7 p.

Research output: Contribution to journalArticle

An Evaluation of Family-Based Treatment for OCD in Japan: A Pilot Randomized Controlled Trial

Kobayashi, Y., Kanie, A., Nakagawa, A., Takebayashi, Y., Shinmei, I., Nakayama, N., Yamaguchi, K., Nakayama, C., Hirabayashi, N., Mimura, M. & Horikoshi, M., 2020 Jan 9, In : Frontiers in Psychiatry. 10, 932.

Research output: Contribution to journalArticle

Open Access

A New Perspective on Dry Eye Classification: Proposal by the Asia Dry Eye Society

Members of The Asia Dry Eye Society, 2020 Jan 1, In : Eye & contact lens. 46, p. S2-S13

Research output: Contribution to journalArticle

1 Citation (Scopus)

A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma

Takakuwa, K., Mogushi, K., Han, M., Fujii, T., Hosoya, M., Yamanami, A., Akita, T., Yamashita, C., Hayashida, T., Kato, S. & Yamaguchi, S., 2020 Dec 1, In : Scientific reports. 10, 1, 6214.

Research output: Contribution to journalArticle

Open Access

A Novel Large Background Sheet for Creating a Clear Microsurgical Field

Uno, T., Ishii, N., Kiuchi, T., Uoya, Y., Yuzaki, I. & Kishi, K., 2020 Jan 1, (Accepted/In press) In : Plastic and Reconstructive Surgery - Global Open. e2771.

Research output: Contribution to journalArticle

Open Access

A novel scale for predicting delayed intubation in patients with inhalation injury

Matsumura, K., Yamamoto, R., Kamagata, T., Kurihara, T., Sekine, K., Takuma, K., Kase, K. & Sasaki, J., 2020 Jan 1, (Accepted/In press) In : Burns.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A novel technique to avoid perforation of the right ventricle by the temporary pacing lead during transcatheter aortic valve implantation

Tanaka, M., Yanagisawa, R., Yashima, F., Arai, T., Watanabe, Y., Naganuma, T., Shirai, S., Araki, M., Tada, N., Yamanaka, F., Shimizu, H., Fukuda, K., Yamamoto, M. & Hayashida, K., 2020 Jan 1, (Accepted/In press) In : Cardiovascular Intervention and Therapeutics.

Research output: Contribution to journalArticle

Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy

Millar, D. G., Ramjiawan, R. R., Kawaguchi, K., Gupta, N., Chen, J., Zhang, S., Nojiri, T., Ho, W. W., Aoki, S., Jung, K., Chen, I., Shi, F., Heather, J. M., Shigeta, K., Morton, L. T., Sepulveda, S., Wan, L., Joseph, R., Minogue, E., Khatri, A. & 9 others, Bardia, A., Ellisen, L. W., Corcoran, R. B., Hata, A. N., Pai, S. I., Jain, R. K., Fukumura, D., Duda, D. G. & Cobbold, M., 2020 Apr 1, In : Nature Biotechnology. 38, 4, p. 420-425 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Antigen-driven selection of antibodies against SSA, SSB and the centromere complex', including a novel antigen, MIS12 complex, in human salivary glands

Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., Kato, S., Tsunoda, K., Arase, H. & Takeuchi, T., 2020 Jan 1, In : Annals of the rheumatic diseases. 79, 1, p. 150-158 9 p.

Research output: Contribution to journalArticle

Open Access

Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn's disease in Japanese and Korean patients: The OPERA study

Saruta, M., Park, D. I., Kim, Y. H., Yang, S. K., Jang, B. I., Cheon, J. H., Im, J. P., Kanai, T., Katsuno, T., Ishiguro, Y., Nagaoka, M., Isogawa, N., Li, Y., Banerjee, A., Ahmad, A., Hassan-Zahraee, M., Clare, R., Gorelick, K. J., Cataldi, F., Watanabe, M. & 1 others, Hibi, T., 2020 Jan 1, In : Intestinal Research. 18, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

Open Access

Antipsychotic treatment in the maintenance phase of schizophrenia: An updated systematic review of the guidelines and algorithms

Shimomura, Y., Kikuchi, Y., Suzuki, T., Uchida, H., Mimura, M. & Takeuchi, H., 2020 Jan, In : Schizophrenia Research. 215, p. 8-16 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Antisynthetase myopathy

Suzuki, S., 2020 Jan 1, In : Clinical Neurology. 60, 3, p. 175-180 6 p.

Research output: Contribution to journalArticle

Open Access

Aortic valve neocuspidization in patients under 65 years old

Iida, Y., Sawa, S., Fujii, S. & Shimizu, H., 2020 Jan 1, (Accepted/In press) In : General thoracic and cardiovascular surgery.

Research output: Contribution to journalArticle

A phase I/IIa double blind single institute trial of low dose sirolimus for Pendred syndrome/DFNB4

Fujioka, M., Akiyama, T., Hosoya, M., Kikuchi, K., Fujiki, Y., Saito, Y., Yoshihama, K., Ozawa, H., Tsukada, K., Nishio, S. Y., Usami, S. I., Matsunaga, T., Hasegawa, T., Sato, Y. & Ogawa, K., 2020 May 1, In : Medicine. 99, 19, p. e19763

Research output: Contribution to journalArticle

Open Access

A Phase II Study of Regorafenib With a Lower Starting Dose in Patients With Metastatic Colorectal Cancer: Exposure–Toxicity Analysis of Unbound Regorafenib and Its Active Metabolites (RESET Trial)

Suzuki, T., Sukawa, Y., Imamura, C., Masuishi, T., Satake, H., Kumekawa, Y., Funakoshi, S., Kotaka, M., Horie, Y., Kawai, S., Okuda, H., Terazawa, T., Kondoh, C., Kato, K., Yoshimura, K., Ishikawa, H., Hamamoto, Y., Boku, N., Takaishi, H. & Kanai, T., 2020 Mar, In : Clinical Colorectal Cancer. 19, 1, p. 13-21.e3

Research output: Contribution to journalArticle

Application of clot-fibrinolysis waveform analysis to assessment of in vitro effects of direct oral anticoagulants on fibrinolysis

Oka, S., Wakui, M., Fujimori, Y., Kuroda, Y., Nakamura, S., Kondo, Y., Nakagawa, T., Katagiri, H. & Murata, M., 2020 Jun 1, In : International Journal of Laboratory Hematology. 42, 3, p. 292-298 7 p.

Research output: Contribution to journalArticle

Approach-oriented coping strategy level may be related to volume of the whole hippocampus in the elderly

Kida, H., Nakajima, S., Shikimoto, R., Ochi, R., Noda, Y., Tsugawa, S., Fujii, S., Takayama, M., Mimura, M. & Niimura, H., 2020 Apr 1, In : Psychiatry and Clinical Neurosciences. 74, 4, p. 270-276 7 p.

Research output: Contribution to journalArticle

Appropriateness of Transcatheter Aortic Valve Replacement: Insight from the OCEAN-TAVI Registry

Inohara, T., Vemulapalli, S., Kohsaka, S., Yashima, F., Watanabe, Y., Shirai, S., Tada, N., Araki, M., Naganuma, T., Yamanaka, F., Ueno, H., Tabata, M., Mizutani, K., Higashimori, A., Takagi, K., Yamamoto, M., Shimizu, H., Fukuda, K. & Hayashida, K., 2020 Jan 1, (Accepted/In press) In : Circulation: Cardiovascular Quality and Outcomes. e006146.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Appropriate timing for a biochemical evaluation after adrenalectomy for unilateral aldosterone-producing adenoma

Takamatsu, K., Takeda, T., Hattori, S., Tanaka, N., Morita, S., Matsumoto, K., Kosaka, T., Mizuno, R., Shinojima, T., Kikuchi, E., Asanuma, H., Kurihara, I., Itoh, H. & Oya, M., 2020 Jun 1, In : Clinical Endocrinology. 92, 6, p. 503-508 6 p.

Research output: Contribution to journalArticle

A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort

Ohwada, C., Sakaida, E., Igarashi, A., Kobayashi, T., Doki, N., Mori, T., Kato, J., Koda, Y., Kanamori, H., Tanaka, M., Tachibana, T., Fujisawa, S., Nakajima, Y., Numata, A., Toyosaki, M., Aoyama, Y., Onizuka, M., Hagihara, M., Koyama, S., Kanda, Y. & 9 others, Nakasone, H., Shimizu, H., Kato, S., Watanabe, R., Shono, K., Sakai, R., Saito, T., Nakaseko, C. & Okamoto, S., 2020 Jan, In : Biology of Blood and Marrow Transplantation. 26, 1, p. 162-170 9 p.

Research output: Contribution to journalArticle

AQP5 enriches for stem cells and cancer origins in the distal stomach

Tan, S. H., Swathi, Y., Tan, S., Goh, J., Seishima, R., Murakami, K., Oshima, M., Tsuji, T., Phuah, P., Tan, L. T., Wong, E., Fatehullah, A., Sheng, T., Ho, S. W. T., Grabsch, H. I., Srivastava, S., Teh, M., Denil, S. L. I. J., Mustafah, S., Tan, P. & 4 others, Shabbir, A., So, J., Yeoh, K. G. & Barker, N., 2020 Feb 20, In : Nature. 578, 7795, p. 437-443 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A rare case of bifurcated chorda tympani

Kasahara, K., Hosoya, M., Oishi, N. & Ogawa, K., 2020 Apr, In : Journal of International Advanced Otology. 16, 1, p. 141-144 4 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Takeishi, K., Collin de l'Hortet, A., Wang, Y., Handa, K., Guzman-Lepe, J., Matsubara, K., Morita, K., Jang, S., Haep, N., Florentino, R. M., Yuan, F., Fukumitsu, K., Tobita, K., Sun, W., Franks, J., Delgado, E. R., Shapiro, E. M., Fraunhoffer, N. A., Duncan, A. W., Yagi, H. & 3 others, Mashimo, T., Fox, I. J. & Soto-Gutierrez, A., 2020 Jun 2, In : Cell Reports. 31, 9, 107711.

Research output: Contribution to journalArticle

Open Access