Department of Internal Medicine (Gastroenterology and Hepatology)

Research Output

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Review article
2020

Clinical and endoscopic characteristics of pyogenic granuloma in the small intestine: A case series with literature review

Hayashi, Y., Dr, N. H., Takabayashi, K., Limpias Kamiya, K. J. L., Mutaguchi, M., Miyanaga, R., Hirata, K., Fukuhara, S., Mikami, Y., Sujino, T., Masugi, Y., Naganuma, M., Ogata, H. & Kanai, T., 2020 Feb 15, In : Internal Medicine. 59, 4, p. 501-505 5 p.

Research output: Contribution to journalReview article

Open Access

Previous Helicobacter pylori infection–induced atrophic gastritis: A distinct disease entity in an understudied population without a history of eradication

Kishikawa, H., Ojiro, K., Nakamura, K., Katayama, T., Arahata, K., Takarabe, S., Miura, S., Kanai, T. & Nishida, J., 2020 Feb 1, In : Helicobacter. 25, 1, e12669.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)
2019

Capsule endoscopy for small-intestinal disorders: Current status

Hosoe, N., Takabayashi, K., Ogata, H. & Kanai, T., 2019 Jan 1, In : Digestive Endoscopy.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Current new challenges in the management of ulcerative colitis

Fukuda, T., Naganuma, M. & Kanai, T., 2019 Jan 1, In : Intestinal Research. 17, 1, p. 36-44 9 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Electric endocut and autocut resection for endoscopic papillectomy: A systematic review

Minami, K., Iwasaki, E., Fukuhara, S., Horibe, M., Seino, T., Kawasaki, S., Katayama, T., Takimoto, Y., Tamagawa, H., MacHida, Y., Kanai, T. & Itoi, T., 2019 Jan 1, In : Internal Medicine. 58, 19, p. 2767-2772 6 p.

Research output: Contribution to journalReview article

Open Access

Epigenetic regulation of T helper cells and intestinal pathogenicity

Hagihara, Y., Yoshimatsu, Y., Mikami, Y., Takada, Y., Mizuno, S. & Kanai, T., 2019 Jan 1, In : Seminars in Immunopathology.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine

Akiyama, S., Matsuoka, K., Fukuda, K., Hamada, S., Shimizu, M., Nanki, K., Mizuno, S., Kiyohara, H., Arai, M., Sugimoto, S., Iwao, Y., Ogata, H., Hisamatsu, T., Naganuma, M., Motobayashi, M., Suzuki, K., Takenaka, K., Fujii, T., Saito, E., Nagahori, M. & 5 others, Ohtsuka, K., Mochizuki, M., Watanabe, M., Hashiguchi, M. & Kanai, T., 2019 Jan 1, In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalReview article

3 Citations (Scopus)

Management of elderly ulcerative colitis in Japan

Higashiyama, M., Sugita, A., Koganei, K., Wanatabe, K., Yokoyama, Y., Uchino, M., Nagahori, M., Naganuma, M., Bamba, S., Kato, S., Takeuchi, K., Omori, T., Takagi, T., Matsumoto, S., Nagasaka, M., Sagami, S., Kitamura, K., Katsurada, T., Sugimoto, K., Takatsu, N. & 6 others, Saruta, M., Sakurai, T., Watanabe, K., Nakamura, S., Suzuki, Y. & Hokari, R., 2019 Jan 1, In : Journal of gastroenterology.

Research output: Contribution to journalReview article

3 Citations (Scopus)

The relationship between gut microbiome, immune system, and cancer

Ichikawa, M., Sujino, T. & Kanai, T., 2019 Dec, In : Japanese Journal of Cancer and Chemotherapy. 46, 12, p. 1807-1813 7 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Treatment with indigo naturalis for inflammatory bowel disease and other immune diseases

Naganuma, M., 2019 Jan 1, In : Immunological Medicine.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
2018
6 Citations (Scopus)

Management of challenging immune-related gastrointestinal adverse events associated with immune checkpoint inhibitors

Hamamoto, Y., Shin, N., Hoshino, T. & Kanai, T., 2018 Dec, In : Future Oncology. 14, 30, p. 3187-3198 12 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Review of the small intestinal mucosal lesion

Hosoe, N., Ogata, H. & Kanai, T., 2018 Jan 1, In : Journal of Japanese Society of Gastroenterology. 115, 7, p. 605-611 7 p.

Research output: Contribution to journalReview article

Treatment strategy for inflammatory bowel disease with a focus on biologicals

Fukuda, T., Naganuma, M. & Kanai, T., 2018 Jan 1, In : Journal of Japanese Society of Gastroenterology. 115, 3, p. 272-282 11 p.

Research output: Contribution to journalReview article

2017

Effect of prophylactic clipping in colorectal endoscopic resection: A meta-analysis of randomized controlled studies

Nishizawa, T., Suzuki, H., Goto, O., Ogata, H., Kanai, T. & Yahagi, N., 2017 Oct 1, In : United European Gastroenterology Journal. 5, 6, p. 859-867 9 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Intestinal immune response is regulated by gut microbe

Shun, T., Tomohisa, S. & Takanori, K., 2017 Jan 1, In : Japanese Journal of Clinical Immunology. 40, 6, p. 408-415 8 p.

Research output: Contribution to journalReview article

2016

Recent trends and future directions for the medical treatment of ulcerative colitis

Naganuma, M., Mizuno, S., Nanki, K., Sugimoto, S. & Kanai, T., 2016 Dec 1, In : Clinical Journal of Gastroenterology. 9, 6, p. 329-336 8 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Timing of oral refeeding in acute pancreatitis: A systematic review and meta-analysis

Horibe, M., Nishizawa, T., Suzuki, H., Minami, K., Yahagi, N., Iwasaki, E. & Kanai, T., 2016 Dec 1, In : United European Gastroenterology Journal. 4, 6, p. 725-732 8 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2015

Current status of capsule endoscopy through a whole digestive tract

Hosoe, N., Naganuma, M. & Ogata, H., 2015 Jan 1, In : Digestive Endoscopy. 27, 2, p. 205-215 11 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Dexmedetomidine versus midazolam for gastrointestinal endoscopy: A meta-analysis

Nishizawa, T., Suzuki, H., Sagara, S., Kanai, T. & Yahagi, N., 2015 Jan 1, In : Digestive Endoscopy. 27, 1, p. 8-15 8 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

Magnetic resonance enterography of Crohn's disease

Naganuma, M., Hisamatsu, T., Kanai, T. & Ogata, H., 2015 Jan 1, In : Expert Review of Gastroenterology and Hepatology. 9, 1, p. 37-45 9 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
11 Citations (Scopus)

Recent trends in diagnostic techniques for inflammatory bowel disease

Naganuma, M., Hosoe, N., Kanai, T. & Ogata, H., 2015 Jan 1, In : Korean Journal of Internal Medicine. 30, 3, p. 271-278 8 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Second-look endoscopy after endoscopic submucosal dissection for gastric neoplasms

Nishizawa, T., Suzuki, H., Kinoshita, S., Goto, O., Kanai, T. & Yahagi, N., 2015 Mar 1, In : Digestive Endoscopy. 27, 3, p. 279-284 6 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

The gut microbiota and inflammatory bowel disease

Matsuoka, K. & Kanai, T., 2015 Jan 1, In : Seminars in Immunopathology. 37, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

224 Citations (Scopus)
2014

[Case report; Small cell neuroendocrine carcinoma of the esophagus producing parathyroid hormone-related peptide with humoral hypercalcemia].

Atsumi, Y., Iwasaki, E., Hoshino, M., Takita, M., Ishiyama, Y., Matsuzaki, J., Kishino, R., Izumiya, M., Nakazawa, A. & Tsukada, N., 2014 Mar 10, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 103, 3, p. 741-743 3 p.

Research output: Contribution to journalReview article

Open Access

Diagnosis and management of intestinal Behçet's diseas

Hisamatsu, T., Naganuma, M., Matsuoka, K. & Kanai, T., 2014 Jun, In : Clinical journal of gastroenterology. 7, 3, p. 205-212 8 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Diet, microbiota, and inflammatory bowel disease: Lessons from Japanese foods

Kanai, T., Matsuoka, K., Naganuma, M., Hayashi, A. & Hisamatsu, T., 2014 Jan 1, In : Korean Journal of Internal Medicine. 29, 4, p. 409-415 7 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Fecal microbiota transplantation for gastrointestinal diseases

Matsuoka, K., Mizuno, S., Hayashi, A., Hisamatsu, T., Naganuma, M. & Kanai, T., 2014 Dec 1, In : Keio Journal of Medicine. 63, 4, p. 69-74 6 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)
11 Citations (Scopus)

Propofol versus traditional sedative agents for endoscopic submucosal dissection

Nishizawa, T., Suzuki, H., Matsuzaki, J., Kanai, T. & Yahagi, N., 2014 Nov 1, In : Digestive Endoscopy. 26, 6, p. 701-706 6 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)
2013

Clinical strategies for the blockade of IL-18 in inflammatory bowel diseases.

Kanai, T., Kamada, N. & Hisamatsu, T., 2013 Nov, In : Current drug targets. 14, 12, p. 1392-1399 8 p.

Research output: Contribution to journalReview article

21 Citations (Scopus)

Immune aspects of the pathogenesis of inflammatory bowel disease

Hisamatsu, T., Kanai, T., Mikami, Y., Yoneno, K., Matsuoka, K. & Hibi, T., 2013 Mar 1, In : Pharmacology and Therapeutics. 137, 3, p. 283-297 15 p.

Research output: Contribution to journalReview article

60 Citations (Scopus)

Mechanism and therapeutic strategy of secondary failure to anti-tumor necrosis factor-α monoclonal antibody treatment for crohn's disease

Matsuoka, K. & Kanai, T., 2013 Jan 1, In : Digestion. 88, 1, p. 17-19 3 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Ulcerative colitis: Prevention of relapse

Naganuma, M., Sakuraba, A. & Hibi, T., 2013 May 1, In : Expert Review of Gastroenterology and Hepatology. 7, 4, p. 341-351 11 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2012

Difficulties in taking aminosalicylates for patients with ulcerative colitis

Kawakami, A., Tanaka, M., Ochiai, R., Naganuma, M., Iwao, Y., Hibi, T. & Kazuma, K., 2012 Jan 1, In : Gastroenterology Nursing. 35, 1, p. 24-31 8 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation

Kanai, T., Mikami, Y., Sujino, T., Hisamatsu, T. & Hibi, T., 2012 May 1, In : Mucosal Immunology. 5, 3, p. 240-247 8 p.

Research output: Contribution to journalReview article

50 Citations (Scopus)
2011

Ghrelin and oxidative stress in gastrointestinal tract

Suzuki, H., Matsuzaki, J. & Hibi, T., 2011 Mar 1, In : Journal of Clinical Biochemistry and Nutrition. 48, 2, p. 122-125 4 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

Transition of treatments of uncreative colitis based on the imaging studies

Kanai, T., Ogata, H., Hosoe, N., Iwao, Y. & Hibi, T., 2011 Oct 1, In : GASTROENTEROLOGICAL ENDOSCOPY. 53, 10, p. 3261-3271 11 p.

Research output: Contribution to journalReview article

What is the difference between Helicobacter pylori- associated dyspepsia and functional dyspepsia?

Suzuki, H., Matsuzaki, J. & Hibi, T., 2011 Apr 1, In : Journal of Neurogastroenterology and Motility. 17, 2, p. 124-130 7 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)
2009

Helicobacter pylori and gastric cancer

Suzuki, H., Iwasaki, E. & Hibi, T., 2009 Jun 1, In : Gastric Cancer. 12, 2, p. 79-87 9 p.

Research output: Contribution to journalReview article

82 Citations (Scopus)

Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease

Kanai, T., Nemoto, Y., Kamada, N., Totsuka, T., Hisamatsu, T., Watanabe, M. & Hibi, T., 2009 Jul 1, In : Current Opinion in Gastroenterology. 25, 4, p. 306-313 8 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

Lifestyle-related diseases and H. pylori

Suzuki, H., Matsuzaki, J. & Hibi, T., 2009 Dec, In : Nippon rinsho. Japanese journal of clinical medicine. 67, 12, p. 2366-2371 6 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Systemically circulating colitogenic memory CD4+ T cells may be an ideal target for the treatment of inflammatory bowel diseases

Kanai, T., Watanabe, M. & Hibi, T., 2009 Dec 1, In : Keio Journal of Medicine. 58, 4, p. 203-209 7 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)
2008

Gastric epithelial cell modality and proton pump inhibitor

Masaoka, T., Suzuki, H. & Hibi, T., 2008 May 1, In : Journal of Clinical Biochemistry and Nutrition. 42, 3, p. 191-196 6 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)
2007

Endoscopic therapy for gastroesophageal reflux disease

Suzuki, H., Iwasaki, E. & Hibi, T., 2007 May, In : Nippon rinsho. Japanese journal of clinical medicine. 65, 5, p. 895-899 5 p.

Research output: Contribution to journalReview article

2006

Ghrelin - a novel appetite-stimulating hormone which also affects gastrointestinal functions

Suzuki, H., Masaoka, T. & Hibi, T., 2006 Aug, In : The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 48, 2, p. 82-88 7 p.

Research output: Contribution to journalReview article

2005

Eradication therapy for the improvement of quality of life in cases of Helicobacter pylori-positive functional dyspepsia

Masaoka, T., Suzuki, H. & Hibi, T., 2005 Nov, In : Nippon rinsho. Japanese journal of clinical medicine. 63 Suppl 11, p. 474-477 4 p.

Research output: Contribution to journalReview article

Helicobacter pylori infection and gastric cancer

Suzuki, H., Nishizawa, T., Masaoka, T., Mori, M., Iwasaki, E., Tsuchimoto, K. & Hibi, T., 2005 Oct 1, In : Japan Medical Association Journal. 48, 10, p. 497-504 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2004

Effect of proton pump inhibitors (PPIs) on wound healing of gastric mucosal cell injury

Masaoka, T., Suzuki, H. & Ishii, H., 2004 Mar, In : Nippon rinsho. Japanese journal of clinical medicine. 62, 3, p. 556-560 5 p.

Research output: Contribution to journalReview article