Department of Internal Medicine (Neurology)

Research Output 1994 2019

2019
1 Citation (Scopus)

Absence of sarcoplasmic myxovirus resistance protein A (MxA) expression in antisynthetase syndrome in a cohort of 194 cases

Inoue, M., Tanboon, J., Okubo, M., Theerawat, K., Saito, Y., Ogasawara, M., Indrawati, L. A., Uruha, A., Okiyama, N., Fujimoto, M., Suzuki, S. & Nishino, I., 2019 Jan 1, In : Neuropathology and Applied Neurobiology.

Research output: Contribution to journalLetter

Myxovirus Resistance Proteins
Staphylococcal Protein A
Antisynthetase syndrome

A case of anti-titin antibody positive nivolumab-related necrotizing myopathy with myasthenia gravis

Isami, A., Uchiyama, A., Shimaoka, Y., Suzuki, S., Kawachi, I. & Fujita, N., 2019 Jul 31, In : Rinsho shinkeigaku = Clinical neurology. 59, 7, p. 431-435 5 p.

Research output: Contribution to journalArticle

Open Access
Connectin
Myasthenia Gravis
Muscular Diseases
Anti-Idiotypic Antibodies
Muscles

Achievement of Durable and Complete Remission of Graft-versus-host Disease After Liver Transplantation With Ruxolitinib: A Case Report

Endo, Y., Oshima, G., Hibi, T., Shinoda, M., Sakurai, M., Koda, Y., Izawa, Y., Obara, H., Kitago, M., Yagi, H., Abe, Y., Matsubara, K., Yamada, Y., Fukushima, A., Yokose, T., Mori, T., Kuroda, T. & Kitagawa, Y., 2019 Nov 1, In : Transplantation. 103, 11, p. e375-e377

Research output: Contribution to journalArticle

Graft vs Host Disease
Liver Transplantation
INCB018424

Alternative to steroid therapy for myasthenia gravis and myositis occurring as immune-related adverse events

Kamada, S., Hanazono, A., Sanpei, Y., Inoue, T., Suzuki, S., Sugawara, M. & Iijima, K., 2019 Jan 1, In : Clinical and Experimental Neuroimmunology.

Research output: Contribution to journalComment/debate

Myositis
Myasthenia Gravis
Anti-Idiotypic Antibodies
Steroids
Therapeutics

Can we predict amyloid deposition by objective cognition and regional cerebral blood flow in patients with subjective cognitive decline?

Funaki, K., Nakajima, S., Noda, Y., Wake, T., Ito, D., Yamagata, B., Yoshizaki, T., Kameyama, M., Nakahara, T., Murakami, K., Jinzaki, M., Mimura, M. & Tabuchi, H., 2019 Jan 1, (Accepted/In press) In : Psychogeriatrics.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Regional Blood Flow
Amyloid
Cognition
Single-Photon Emission-Computed Tomography

Cerebral Infarction after Transcatheter Aortic Valve Implantation in Japan: Retrospective Analysis at a Single High-Volume Center

Iizuka, T., Oki, K., Hayashida, K., Minami, K., Izawa, Y., Takahashi, S., Shimizu, H., Fukuda, K. & Nakahara, J., 2019 Jan 1, (Accepted/In press) In : Journal of Stroke and Cerebrovascular Diseases. 104455.

Research output: Contribution to journalArticle

Cerebral Infarction
Japan
Catheters
Transcatheter Aortic Valve Replacement
Carotid Stenosis

Concurrent positive anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase antibody with reducing body myopathy: Possible double trouble

Tanboon, J., Sanmaneechai, O., Charuvanij, S., Sangruchi, T., Galindo-Feria, A. S., Lundberg, I. E., Ohnuki, Y., Shiina, T., Suzuki, S. & Nishino, I., 2019 Jan 1, In : Neuromuscular Disorders.

Research output: Contribution to journalArticle

Coenzymes
Muscular Diseases
Oxidoreductases
Antibodies
Immunotherapy
1 Citation (Scopus)

Cytometric cell-based assays for anti-striational antibodies in myasthenia gravis with myositis and/or myocarditis

Kufukihara, K., Watanabe, Y., Inagaki, T., Takamatsu, K., Nakane, S., Nakahara, J., Ando, Y. & Suzuki, S., 2019 Dec 1, In : Scientific reports. 9, 1, 5284.

Research output: Contribution to journalArticle

Open Access
Myositis
Myasthenia Gravis
Myocarditis
Connectin
Anti-Idiotypic Antibodies

Diagnostic Potential of Multimodal MRI Markers in Atypical Parkinsonian Disorders

Seki, M., Seppi, K., Mueller, C., Potrusil, T., Goebel, G., Reiter, E., Nocker, M., Kremser, C., Wildauer, M., Schocke, M., Gizewski, E. R., Wenning, G. K., Poewe, W. & Scherfler, C., 2019 Jan 1, In : Journal of Parkinson's Disease. 9, 4, p. 681-691 11 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Progressive Supranuclear Palsy
Parkinsonian Disorders
ROC Curve
Parkinson Disease

Eculizumab improved weakness and taste disorder in thymoma-associated generalized myasthenia gravis with anti-striational antibodies: A case report

Amano, E., Otsu, S., Suzuki, S. & Machida, A., 2019 Mar 1, In : eNeurologicalSci. 14, p. 72-73 2 p.

Research output: Contribution to journalLetter

Taste Disorders
Thymoma
Myasthenia Gravis
Anti-Idiotypic Antibodies
eculizumab
Dopamine Plasma Membrane Transport Proteins
Fractals
Single-Photon Emission-Computed Tomography
Putamen
Parkinsonian Disorders
Open Access
Parkinsonian Disorders
Masks
Single-Photon Emission-Computed Tomography
Cerebrospinal Fluid
Confidence Intervals
4 Citations (Scopus)

Inflammatory myopathy associated with PD-1 inhibitors

Seki, M., Uruha, A., Ohnuki, Y., Kamada, S., Noda, T., Onda, A., Ohira, M., Isami, A., Hiramatsu, S., Hibino, M., Nakane, S., Noda, S., Yutani, S., Hanazono, A., Yaguchi, H., Takao, M., Shiina, T., Katsuno, M., Nakahara, J., Matsubara, S. & 2 others, Nishino, I. & Suzuki, S., 2019 Jun 1, In : Journal of Autoimmunity. 100, p. 105-113 9 p.

Research output: Contribution to journalArticle

Myositis
Muscular Diseases
Muscle Weakness
Myalgia
Signal Recognition Particle

Myelopathy due to human T-cell leukemia virus type-1 from the donor after ABO-incompatible liver transplantation

Wakabayashi, T., Obara, H., Seki, M., Shinoda, M., Kitago, M., Yagi, H., Abe, Y., Matsubara, K., Yamada, Y., Oshima, G., Oki, K., Nagoshi, N., Watanabe, K., Hibi, T., Itano, O., Hoshino, K., Suzuki, N., Kuroda, T. & Kitagawa, Y., 2019 Mar 1, In : Annals of hepatology. 18, 2, p. 397-401 5 p.

Research output: Contribution to journalArticle

Open Access
Deltaretrovirus
Spinal Cord Diseases
Liver Transplantation
Transplantation
Tissue Donors

Neurovascular coupling during optogenetic functional activation: Local and remote stimulus-response characteristics, and uncoupling by spreading depression

Böhm, M., Chung, D. Y., Gómez, C. A., Qin, T., Takizawa, T., Sadeghian, H., Sugimoto, K., Sakadžić, S., Yaseen, M. A. & Ayata, C., 2019 Jan 1, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Optogenetics
Hyperemia
Cortical Spreading Depression
Motor Cortex
Skull
2 Citations (Scopus)

Pembrolizumab-induced ocular Myasthenia Gravis with anti-titin antibody and necrotizing myopathy

Onda, A., Miyagawa, S., Takahashi, N., Gochi, M., Takagi, M., Nishino, I., Suzuki, S., Oishi, C. & Yaguchi, H., 2019 Jan 1, In : Internal Medicine. 58, 11, p. 1635-1638 4 p.

Research output: Contribution to journalArticle

Open Access
Connectin
Myasthenia Gravis
Muscular Diseases
Anti-Idiotypic Antibodies
Autoantibodies
Open Access
Clinical Trials, Phase I
Amyotrophic Lateral Sclerosis
Labels
Placebos
Stem cells

Spatiotemporal dynamics of red blood cells in capillaries in layer I of the cerebral cortex and changes in arterial diameter during cortical spreading depression and response to hypercapnia in anesthetized mice

Unekawa, M., Tomita, Y., Toriumi, H., Osada, T., Masamoto, K., Kawaguchi, H., Izawa, Y., Itoh, Y., Kanno, I., Suzuki, N. & Nakahara, J., 2019 Jan 1, In : Microcirculation. e12552.

Research output: Contribution to journalArticle

Cortical Spreading Depression
Hypercapnia
Cerebral Cortex
Erythrocytes
Cerebrovascular Circulation
3 Citations (Scopus)

Spreading depression as a preclinical model of migraine

Harriott, A. M., Takizawa, T., Chung, D. Y. & Chen, S. P., 2019 May 2, In : Journal of Headache and Pain. 20, 1, 45.

Research output: Contribution to journalReview article

Open Access
Migraine Disorders
Optogenetics
Neuroglia
Epilepsy
Theoretical Models

Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors

Matsubara, S., Seki, M., Suzuki, S., Komori, T. & Takamori, M., 2019 Sep 18, In : Journal for ImmunoTherapy of Cancer. 7, 1, 256.

Research output: Contribution to journalArticle

Open Access
Myositis
Muscles
Polymyositis
Blood Vessels
Lymphocytes
1 Citation (Scopus)

Three cases of non-carryover fingolimod-PML: Is the risk in Japan increased?

Nakahara, J., Tomaske, L., Kume, K., Takata, T., Kamada, M., Deguchi, K., Kufukihara, K., Schneider, R., Gold, R. & Ayzenberg, I., 2019 May 1, In : Neurology: Neuroimmunology and NeuroInflammation. 6, 3, e559.

Research output: Contribution to journalArticle

Open Access
Progressive Multifocal Leukoencephalopathy
Japan
Immune Reconstitution Inflammatory Syndrome
IgG Deficiency
Mycoses
2018
Internal Carotid Artery
Angioplasty
Carotid Arteries
Carotid Stenosis
Infarction

Clinical analysis of opticospinal multiple sclerosis (OSMS) presentation detecting anti-myelin oligodendrocyte glycoprotein (MOG) antibody

Kitagawa, S., Osada, T., Kaneko, K., Takahashi, T., Suzuki, N. & Nakahara, J., 2018 Jan 1, In : Clinical Neurology. 58, 12, p. 737-744 8 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Antibodies
Spinal Cord
Oligoclonal Bands
Paresis

Continuation of axitinib for advanced renal cell carcinoma by the application of homecare urology-a case report and literature review

Yazawa, S., Kato, Y., Nakahara, J., Miyata, T. & Oya, M., 2018 Apr 1, In : Japanese Journal of Cancer and Chemotherapy. 45, 4, p. 639-642 4 p.

Research output: Contribution to journalArticle

Urology
Renal Cell Carcinoma
Valsartan
Antifoaming Agents
Medicine
5 Citations (Scopus)

Diagnostic potential of sarcoplasmic myxovirus resistance protein A expression in subsets of dermatomyositis

Uruha, A., Allenbach, Y., Charuel, J. L., Musset, L., Aussy, A., Boyer, O., Mariampillai, K., Landon-Cardinal, O., Rasmussen, C., Bolko, L., Maisonobe, T., Leonard-Louis, S., Suzuki, S., Nishino, I., Stenzel, W. & Benveniste, O., 2018 Jan 1, (Accepted/In press) In : Neuropathology and Applied Neurobiology.

Research output: Contribution to journalArticle

Myxovirus Resistance Proteins
Dermatomyositis
Staphylococcal Protein A
Tretinoin
Atrophy
1 Citation (Scopus)

Diameter of fluorescent microspheres determines their distribution throughout the cortical watershed area in mice

Tsukada, N., Katsumata, M., Oki, K., Minami, K., Abe, T., Takahashi, S., Itoh, Y. & Suzuki, N., 2018 Jan 15, In : Brain Research. 1679, p. 109-115 7 p.

Research output: Contribution to journalArticle

Microspheres
Common Carotid Artery
Ligation
Middle Cerebral Artery
Embolism
5 Citations (Scopus)

Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology

Kayama, Y., Shibata, M., Takizawa, T., Ibata, K., Shimizu, T., Ebine, T., Toriumi, H., Yuzaki, M. & Suzuki, N., 2018 Apr 1, In : Cephalalgia. 38, 5, p. 833-845 13 p.

Research output: Contribution to journalArticle

Vasopressin Receptors
Migraine Disorders
Trigeminal Ganglion
Neurons
Pain Threshold

Immune checkpoint inhibitors and neuromuscular adverse events

Suzuki, S., 2018 Apr 1, In : Brain and Nerve. 70, 4, p. 461-466 6 p.

Research output: Contribution to journalReview article

Myositis
Dysgeusia
Therapeutics
Neoplasms
Polyneuropathies
5 Citations (Scopus)

Immune checkpoint inhibitors in the onset of myasthenia gravis with hyperCKemia

Takamatsu, K., Nakane, S., Suzuki, S., Kosaka, T., Fukushima, S., Kimura, T., Miyashita, A., Mukaino, A., Yamakawa, S., Watanabe, K., Jinnin, M., Komohara, Y., Ihn, H. & Ando, Y., 2018 Jan 1, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Myasthenia Gravis
Anti-Idiotypic Antibodies
Myositis
Progressive Multifocal Leukoencephalopathy
Cerebral Cortex
4 Citations (Scopus)

Mitophagy in three cases of immune-mediated necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: Ultrastructural and immunohistochemical studies

Matsubara, S., Bokuda, K., Asano, Y., Morishima, R., Sugaya, K., Miyamoto, K., Koide, R., Komori, T., Suzuki, S. & Nishino, I., 2018 Jan 1, (Accepted/In press) In : Neuromuscular Disorders.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Muscular Diseases
Autoantibodies
Oxidoreductases
Hydroxymethylglutaryl-CoA Reductase Inhibitors

Neuromuscular adverse events

Suzuki, S., 2018 Jul 1, In : Japanese Journal of Cancer and Chemotherapy. 45, 7, p. 1036-1040 5 p.

Research output: Contribution to journalArticle

Myositis
Dysgeusia
Second Primary Neoplasms
Polyneuropathies
Neuromuscular Junction
4 Citations (Scopus)

Neuroprotective Role of Astroglia in Parkinson Disease by Reducing Oxidative Stress Through Dopamine-Induced Activation of Pentose-Phosphate Pathway

Mashima, K., Takahashi, S., Minami, K., Izawa, Y., Abe, T., Tsukada, N., Hishiki, T., Suematsu, M., Kajimura, M. & Suzuki, N., 2018 May 1, In : ASN Neuro. 10

Research output: Contribution to journalArticle

Pentose Phosphate Pathway
Astrocytes
Parkinson Disease
Dopamine
Oxidative Stress

New criteria needed for antisynthetase syndrome - Reply

Suzuki, S., Uruha, A. & Nishino, I., 2018 Feb 1, In : JAMA Neurology. 75, 2, p. 259-260 2 p.

Research output: Contribution to journalLetter

Antisynthetase syndrome
3 Citations (Scopus)

Quantitative evaluation of the tracer distribution in dopamine transporter SPECT for objective interpretation

Iwabuchi, Y., Nakahara, T., Kameyama, M., Yamada, Y., Hashimoto, M., Ogata, Y., Matsusaka, Y., Katagiri, M., Itoh, K., Osada, T., Ito, D., Tabuchi, H. & Jinzaki, M., 2018 Apr 13, (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-9 9 p.

Research output: Contribution to journalArticle

Fractals
Dopamine Plasma Membrane Transport Proteins
Single-Photon Emission-Computed Tomography
Parkinsonian Disorders
ROC Curve
3 Citations (Scopus)

Rationale for the clinical guidelines for myasthenia gravis in Japan

Murai, H., Utsugisawa, K., Nagane, Y., Suzuki, S., Imai, T. & Motomura, M., 2018 Jan 1, (Accepted/In press) In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalArticle

Myasthenia Gravis
Prednisolone
Japan
Guidelines
Intravenous Immunoglobulins
4 Citations (Scopus)

Real-time non-invasive in vivo visible light detection of cortical spreading depolarizations in mice

Chung, D. Y., Sugimoto, K., Fischer, P., Böhm, M., Takizawa, T., Sadeghian, H., Morais, A., Harriott, A., Oka, F., Qin, T., Henninger, N., Yaseen, M. A., Sakadžić, S. & Ayata, C., 2018 Nov 1, In : Journal of Neuroscience Methods. 309, p. 143-146 4 p.

Research output: Contribution to journalArticle

Lighting
Light
Rheology
Laser-Doppler Flowmetry
Lasers
12 Citations (Scopus)

Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial

Japanese Eculizumab Trial for GBS (JET-GBS) Study Group, 2018 Jun 1, In : The Lancet Neurology. 17, 6, p. 519-529 11 p.

Research output: Contribution to journalArticle

Safety
Placebos
Anaphylaxis
Abscess
Japan

Should multiple sclerosis be only treated by experts?

Nakahara, J., 2018 Jan 1, In : Neuro-Ophthalmology Japan. 35, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Immune System
Pharmaceutical Preparations
Demyelinating Diseases
Drug Delivery Systems

Significance of follow-up thoracic imaging in myasthenia gravis

Murai, H., Nagane, Y., Suzuki, S., Imai, T., Motomura, M. & Utsugisawa, K., 2018 Nov 1, In : Clinical and Experimental Neuroimmunology. 9, 4, p. 246-250 5 p.

Research output: Contribution to journalArticle

Myasthenia Gravis
Thorax
Thymoma
Lung Neoplasms
Lymph Nodes
87 Citations (Scopus)

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

EXPAND Clinical Investigators, 2018 Mar 31, In : The Lancet. 391, 10127, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Placebos
1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid
Bradycardia
Safety

The first report of a japanese case of seipinopathy with a BSCL2 N88S mutation

Minami, K., Takahashi, S., Nihei, Y., Oki, K., Suzuki, S., Ito, D., Takashima, H. & Suzuki, N., 2018 Jan 1, In : Internal Medicine. 57, 4, p. 613-615 3 p.

Research output: Contribution to journalArticle

Congenital Generalized Lipodystrophy
Motor Neurons
Mutation
Genes
Abnormal Reflexes
1 Citation (Scopus)

Trends of Antiplatelet Therapy for the Management of Moyamoya Disease in Japan: Results of a Nationwide Survey

Research Committee on Spontaneous Occlusion of Circle of Willis (Moyamoya disease), 2018 Dec 1, In : Journal of Stroke and Cerebrovascular Diseases. 27, 12, p. 3605-3612 8 p.

Research output: Contribution to journalArticle

Moyamoya Disease
Platelet Aggregation Inhibitors
Japan
Asymptomatic Diseases
pamidronate
6 Citations (Scopus)

β1-integrin–matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability

Izawa, Y., Gu, Y. H., Osada, T., Kanazawa, M., Hawkins, B. T., Koziol, J. A., Papayannopoulou, T., Spatz, M. & del Zoppo, G. J., 2018 Apr 1, In : Journal of Cerebral Blood Flow and Metabolism. 38, 4, p. 641-658 18 p.

Research output: Contribution to journalArticle

Intercellular Junctions
Tight Junctions
Microvessels
Integrins
Permeability

重症筋無力症,全身性エリテマトーデス,関節リウマチを合併した外陰部悪性黒色腫に対してニボルマブ投与と放射線療法が奏功した 1 例

Translated title of the contribution: Successful treatment with nivolumab and concomitant radiation therapy under control of autoimmune diseasesOta, A., Aoyama, R., Tanemura, A., Kotobuki, Y., Katayama, I., Kakuta, K., Tsujimoto, K., Tanaka, T. & Suzuki, S., 2018 Jan 1, In : Skin research. 17, 2, p. 62-69 8 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Radiotherapy
Melanoma
Psychosexual Development
Recurrence
2017
12 Citations (Scopus)

A case of myasthenia gravis and myositis induced by nivolumab

Konoeda, F., Suzuki, S., Nishimoto, Y., Hoshino, H. & Takagi, M., 2017, In : Clinical Neurology. 57, 7, p. 373-377 5 p.

Research output: Contribution to journalArticle

Myositis
Myasthenia Gravis
Programmed Cell Death 1 Receptor
Plasma Exchange
Positive-Pressure Respiration
6 Citations (Scopus)

A clinical predictive score for postoperative myasthenic crisis

Kanai, T., Uzawa, A., Sato, Y., Suzuki, S., Kawaguchi, N., Himuro, K., Oda, F., Ozawa, Y., Nakahara, J., Suzuki, N., Takahashi, Y. K., Ishibashi, S., Yokota, T., Ogawa, T., Yokoyama, K., Hattori, N., Izaki, S., Oji, S., Nomura, K., Kaneko, J. & 3 others, Nishiyama, K., Yoshino, I. & Kuwabara, S., 2017 Nov 1, In : Annals of Neurology. 82, 5, p. 841-849 9 p.

Research output: Contribution to journalArticle

Muscle Weakness
Myasthenia Gravis
Thymectomy
Logistic Models
Vital Capacity

Board Walk

Shibata, M. & Purdy, R. A., 2017 Mar 1, In : Cephalalgia : an international journal of headache. 37, 3, p. 296-297 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Childhood-onset anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) necrotizing myopathy needs to be distinguished from muscular dystrophy: A case study

Hama, Y., Mori-Yoshimura, M., Komaki, H., Suzuki, S., Kohsaka, H., Nishino, I. & Takahashi, Y., 2017 Jan 1, In : Clinical Neurology. 57, 10, p. 567-572 6 p.

Research output: Contribution to journalArticle

Muscular Dystrophies
Muscular Diseases
Oxidoreductases
Myositis
Muscles
5 Citations (Scopus)

Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma

Shiihashi, G., Ito, D., Arai, I., Kobayashi, Y., Hayashi, K., Otsuka, S., Nakajima, K., Yuzaki, M., Itohara, S. & Suzuki, N., 2017, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Sarcoma
Homeostasis
Messenger RNA
Brain