Department of Internal Medicine (Pulmonary Medicine)

Research Output 1997 2019

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Article
2019
1 Citation (Scopus)

Airway M Cells arise in the lower airway due to RANKL signaling and reside in the bronchiolar epithelium associated with iBALT in murine models of respiratory disease

Kimura, S., Mutoh, M., Hisamoto, M., Saito, H., Takahashi, S., Asakura, T., Ishii, M., Nakamura, Y., Iida, J., Hase, K. & Iwanaga, T., 2019 Jan 1, In : Frontiers in Immunology. 10, JUN, 1323.

Research output: Contribution to journalArticle

Open Access
Lymphoid Tissue
Bronchi
Epithelium
Respiratory System
Glycoproteins
2 Citations (Scopus)

A novel smoking cessation smartphone app integrated with a mobile carbon monoxide checker for smoking cessation treatment: Protocol for a randomized controlled trial

Nomura, A., Tateno, H., Masaki, K., Muto, T., Suzuki, S., Satake, K., Hida, E. & Fukunaga, K., 2019 Feb 1, In : Journal of medical Internet research. 21, 2, e12252.

Research output: Contribution to journalArticle

Open Access
Withholding Treatment
Smoking Cessation
Carbon Monoxide
Clinical Protocols
Randomized Controlled Trials
1 Citation (Scopus)

A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients

Tani, T., Naoki, K., Yasuda, H., Arai, D., Ishioka, K., Ohgino, K., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T. & Soejima, K., 2019 Jan 1, (Accepted/In press) In : Cancer Chemotherapy and Pharmacology.

Research output: Contribution to journalArticle

Chemotherapy
Non-Small Cell Lung Carcinoma
Cells
Drug Therapy
Mutation
4 Citations (Scopus)

A Therapeutic Strategy for All Pneumonia Patients: A 3-Year Prospective Multicenter Cohort Study Using Risk Factors for Multidrug-resistant Pathogens to Select Initial Empiric Therapy

Maruyama, T., Fujisawa, T., Ishida, T., Ito, A., Oyamada, Y., Fujimoto, K., Yoshida, M., Maeda, H., Miyashita, N., Nagai, H., Imamura, Y., Shime, N., Suzuki, S., Amishima, M., Higa, F., Kobayashi, H., Suga, S., Tsutsui, K., Kohno, S., Brito, V. & 1 others, Niederman, M. S., 2019 Mar 19, In : Clinical Infectious Diseases. 68, 7, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

Open Access
Multicenter Studies
Pneumonia
Cohort Studies
Ventilator-Associated Pneumonia
Therapeutics

Black pleural effusion caused by pancreatic pseudocyst rupture

Ishigaki, S., Kuwae, M., Ishii, M., Asakura, T., Ueda, S. & Betsuyaku, T., 2019 Feb 1, In : Clinical Case Reports. 7, 2, p. 385-386 2 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Pseudocyst
Pleural Effusion
Rupture
Alcoholic Pancreatitis
Chronic Pancreatitis
1 Citation (Scopus)

Calorie restriction enhances adult mouse lung stem cells function and reverses several ageing-induced changes

Hegab, A. E., Ozaki, M., Meligy, F. Y., Nishino, M., Kagawa, S., Ishii, M. & Betsuyaku, T., 2019 Jan 1, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Aging of materials
Lung
Epithelial Cells
1 Citation (Scopus)

Deficiency of CRTH2, a prostaglandin D 2 receptor, aggravates bleomycin-induced pulmonary inflammation and fibrosis

Ueda, S., Fukunaga, K., Takihara, T., Shiraishi, Y., Oguma, T., Shiomi, T., Suzuki, Y., Ishii, M., Sayama, K., Kagawa, S., Hirai, H., Nagata, K., Nakamura, M., Miyasho, T., Betsuyaku, T. & Asano, K., 2019 Mar 1, In : American journal of respiratory cell and molecular biology. 60, 3, p. 289-298 10 p.

Research output: Contribution to journalArticle

Prostaglandins D
Pulmonary Fibrosis
Bleomycin
Pneumonia
Th2 Cells

Disseminated histoplasmosis from a calcified lung nodule after long-term corticosteroid therapy in an elderly Japanese patient: A case report

Kobayashi, K., Asakura, T., Kawada, I., Hasegawa, H., Chubachi, S., Ohara, K., Kuramoto, J., Sugiura, H., Fujishima, S., Iwata, S., Umeyama, T., Katano, H., Uwamino, Y., Miyazaki, Y., Kamei, K., Hasegawa, N. & Betsuyaku, T., 2019 Apr 1, In : Medicine. 98, 17, p. e15264

Research output: Contribution to journalArticle

Open Access
Histoplasmosis
Adrenal Cortex Hormones
Lung
Fever
meropenem
6 Citations (Scopus)

Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis

Miyata, J., Fukunaga, K., Kawashima, Y., Watanabe, T., Saitoh, A., Hirosaki, T., Araki, Y., Kikawada, T., Betsuyaku, T., Ohara, O. & Arita, M., 2019 Jan 1, In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Nasal Polyps
Eosinophils
Fatty Acids
Arachidonate 15-Lipoxygenase
Lipid Metabolism
1 Citation (Scopus)

Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer-associated fibroblasts

Hegab, A. E., Ozaki, M., Kameyama, N., Gao, J., Kagawa, S., Yasuda, H., Soejima, K., Yin, Y., Guzy, R. D., Nakamura, Y., Ornitz, D. M. & Betsuyaku, T., 2019 Jan 1, In : Journal of Pathology.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Fibroblast Growth Factors
Neoplasms
Lung
Cancer-Associated Fibroblasts
6 Citations (Scopus)

Efficacy of afatinib or osimertinib plus cetuximab combination therapy for non-small-cell lung cancer with EGFR exon 20 insertion mutations

Hasegawa, H., Yasuda, H., Hamamoto, J., Masuzawa, K., Tani, T., Nukaga, S., Hirano, T., Kobayashi, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Lung Cancer. 127, p. 146-152 7 p.

Research output: Contribution to journalArticle

Insertional Mutagenesis
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Exons
Therapeutics

Factors associated with improvements in subjective symptoms of obstructive sleep apnea syndrome after continuous positive airway pressure therapy

Otsuka, K., Fukunaga, K., WakakoYamasawa, Haraguchi, M., Tani, T., Shirahama, R. & Betsuyaku, T., 2019 Jan 1, In : Sleep and Breathing.

Research output: Contribution to journalArticle

Continuous Positive Airway Pressure
Obstructive Sleep Apnea
Therapeutics
Sleep
Depression

First report of hepatobiliary Mycobacterium avium infection developing obstructive jaundice in a patient with neutralizing anti–interferon-gamma autoantibodies

Namkoong, H., Asakura, T., Ishii, M., Yoda, S., Masaki, K., Sakagami, T., Iwasaki, E., Yamagishi, Y., Kanai, T., Betsuyaku, T. & Hasegawa, N., 2019 Jan 1, In : New Microbes and New Infections. 27, p. 4-6 3 p.

Research output: Contribution to journalArticle

Mycobacterium avium
Mycobacterium Infections
Obstructive Jaundice
Autoantibodies
Jaundice
3 Citations (Scopus)

Impact of a novel smartphone app (cureapp smoking cessation) on nicotine dependence: Prospective single-arm interventional pilot study

Masaki, K., Tateno, H., Kameyama, N., Morino, E., Watanabe, R., Sekine, K., Ono, T., Satake, K., Suzuki, S., Nomura, A., Betsuyaku, T. & Fukunaga, K., 2019 Feb 1, In : Journal of medical Internet research. 21, 2, e12694.

Research output: Contribution to journalArticle

Open Access
Tobacco Use Disorder
Smoking Cessation
National Health Programs
Ambulatory Care Facilities
Smartphone

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations

Ikemura, S., Yasuda, H., Matsumoto, S., Kamada, M., Hamamoto, J., Masuzawa, K., Kobayashi, K., Manabe, T., Arai, D., Nakachi, I., Kawada, I., Ishioka, K., Nakamura, M., Namkoong, H., Naoki, K., Ono, F., Araki, M., Kanada, R., Ma, B., Hayashi, Y. & 8 others, Mimaki, S., Yoh, K., Kobayashi, S. S., Kohno, T., Okuno, Y., Goto, K., Tsuchihara, K. & Soejima, K., 2019 May 14, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10025-10030 6 p.

Research output: Contribution to journalArticle

Open Access
Molecular Dynamics Simulation
Lung Neoplasms
Mutation
Pharmaceutical Preparations
Protein-Tyrosine Kinases

Monomer preference of EGFR tyrosine kinase inhibitors influences the synergistic efficacy of combination therapy with cetuximab

Oashi, A., Yasuda, H., Kobayashi, K., Tani, T., Hamamoto, J., Masuzawa, K., Manabe, T., Terai, H., Ikemura, S., Kawada, I., Naoki, K. & Soejima, K., 2019 Jan 1, In : Molecular cancer therapeutics. 18, 9, p. 1593-1601 9 p.

Research output: Contribution to journalArticle

Dimerization
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Therapeutics

MULTIOMICS ANALYSIS OF HUMAN EOSINOPHILS REVEALED MOLECULAR MECHANISM OF EOSINOPHILIC RHINOSINUSITIS AND SEVERE ASTHMA

Miyata, J., Kawashima, Y., Ohara, O., Betsuyaku, T., Fukunaga, K. & Arita, M., 2019 Jan 1, In : Arerugi = [Allergy]. 68, 2, p. 86-91 6 p.

Research output: Contribution to journalArticle

Eosinophils
Asthma

Neutrophil-to-lymphocyte ratio as a novel independent predictor of severe exacerbation in patients with asthma

Mochimaru, T., Ueda, S., Suzuki, Y., Asano, K. & Fukunaga, K., 2019 Jan 1, (Accepted/In press) In : Annals of Allergy, Asthma and Immunology.

Research output: Contribution to journalArticle

Neutrophils
Asthma
Lymphocytes

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice

Namkoong, H., Ishii, M., Fujii, H., Asami, T., Yagi, K., Suzuki, S., Azekawa, S., Tasaka, S., Hasegawa, N. & Betsuyaku, T., 2019 May 28, In : Biochemical and Biophysical Research Communications. 513, 2, p. 405-411 7 p.

Research output: Contribution to journalArticle

Interferon Type I
Obese Mice
Virus Diseases
Nutrition
Orthomyxoviridae

Predictive and modifying factors of bone mineral density decline in patients with COPD

Kameyama, N., Chubachi, S., Sasaki, M., Tsutsumi, A., Irie, H., Sakurai, K., Sayama, K., Nakamura, H., Asano, K., Betsuyaku, T. & Fukunaga, K., 2019 Mar 1, In : Respiratory Medicine. 148, p. 13-23 11 p.

Research output: Contribution to journalArticle

Bone Density
Chronic Obstructive Pulmonary Disease
Diphosphonates
Emphysema
Human Body

Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients

Kamo, T., Tasaka, S., Suzuki, T., Asakura, T., Suzuki, S., Yagi, K., Namkoong, H., Ishii, M., Morisaki, H. & Betsuyaku, T., 2019 Feb 11, In : BMC Pulmonary Medicine. 19, 1, 37.

Research output: Contribution to journalArticle

Open Access
Adult Respiratory Distress Syndrome
Berlin
Lactic Acid
Tomography
APACHE

Rare presentation of anaphylaxis: Pancake syndrome

Masaki, K., Fukunaga, K., Kawakami, Y. & Haque, R., 2019 Mar 1, In : BMJ case reports. 12, 3, e228854.

Research output: Contribution to journalArticle

Dermatophagoides farinae
Mites
Flour
Anaphylaxis
Eating
1 Citation (Scopus)

Retrospective evaluation of natural course in mild cases of Mycobacterium avium complex pulmonary disease

for the Non-Tuberculous Mycobacteriosis-Japan Research Consortium (NTM-JRC), 2019 Apr 1, In : PloS one. 14, 4, e0216034.

Research output: Contribution to journalArticle

Open Access
Mycobacterium avium complex
Mycobacterium avium Complex
Pulmonary diseases
respiratory tract diseases
Lung Diseases

Sitafloxacin-containing regimen for the treatment of refractory mycobacterium avium complex lung disease

Asakura, T., Suzuki, S., Fukano, H., Okamori, S., Kusumoto, T., Uwamino, Y., Ogawa, T., So, M., Uno, S., Namkoong, H., Yoshida, M., Kamata, H., Ishii, M., Nishimura, T., Hoshino, Y. & Hasegawa, N., 2019 Apr 1, In : Open Forum Infectious Diseases. 6, 4, ofz108.

Research output: Contribution to journalArticle

Open Access
Mycobacterium avium Complex
Lung Diseases
Sputum
Therapeutics
Macrolides

Sleep stage detection using only heart rate

Mitsukura, Y., Fukunaga, K., Yasui, M. & Mimura, M., 2019 Jan 1, In : Health Informatics Journal.

Research output: Contribution to journalArticle

Sleep Stages
Sleep
Heart Rate
Polysomnography
Sleep Deprivation

TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations

Udagawa, H., Hasako, S., Ohashi, A., Fujioka, R., Hakozaki, Y., Shibuya, M., Abe, N., Komori, T., Haruma, T., Terasaka, M., Fujita, R., Hashimoto, A., Funabashi, K., Yasuda, H., Miyadera, K., Goto, K., Costa, D. B. & Kobayashi, S. S., 2019 Nov 1, In : Molecular cancer research : MCR. 17, 11, p. 2233-2243 11 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Mutation
Exons
Lung Neoplasms
Insertional Mutagenesis
2018
6 Citations (Scopus)

Anti-inflammatory roles of mesenchymal stromal cells during acute Streptococcus pneumoniae pulmonary infection in mice

Asami, T., Ishii, M., Namkoong, H., Yagi, K., Tasaka, S., Asakura, T., Suzuki, S., Kamo, T., Okamori, S., Kamata, H., Zhang, H., Hegab, A. E., Hasegawa, N. & Betsuyaku, T., 2018 Mar 1, In : Cytotherapy. 20, 3, p. 302-313 12 p.

Research output: Contribution to journalArticle

Pneumococcal Infections
Mesenchymal Stromal Cells
Anti-Inflammatory Agents
Lung
Streptococcus pneumoniae
2 Citations (Scopus)

Aspergillus precipitating antibody in patients with Mycobacterium avium complex lung disease: A cross-sectional study

Suzuki, S., Asakura, T., Namkoong, H., Okamori, S., Yagi, K., Kamata, H., Uwamino, Y., Funatsu, Y., Nakano, Y., Nishimura, T., Ishii, M., Ebihara, T., Betsuyaku, T. & Hasegawa, N., 2018 May 1, In : Respiratory Medicine. 138, p. 1-6 6 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Aspergillus
Lung Diseases
Cross-Sectional Studies
Antibodies

Association between six-minute walk test parameters and the health-related quality of life in patients with pulmonary Mycobacterium avium complex disease

Yagi, K., Asakura, T., Namkoong, H., Suzuki, S., Asami, T., Okamori, S., Kusumoto, T., Funatsu, Y., Kamata, H., Nishimura, T., Ishii, M., Betsuyaku, T. & Hasegawa, N., 2018 Jul 13, In : BMC Pulmonary Medicine. 18, 1, 114.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Quality of Life
Lung
Walk Test
Health Surveys

Bilateral upper lobe Pneumocystis pneumonia during aerosolized pentamidine prophylaxis

Ohara, Y., Asakura, T., Ueda, S., Yamada, Y., Ishii, M. & Betsuyaku, T., 2018 May 1, In : QJM. 111, 5, p. 337-338 2 p.

Research output: Contribution to journalArticle

Pentamidine
Pneumocystis Pneumonia
10 Citations (Scopus)

Clarithromycin expands CD11b+Gr-1+cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia

Namkoong, H., Ishii, M., Fujii, H., Yagi, K., Asami, T., Asakura, T., Suzuki, S., Hegab, A. E., Kamata, H., Tasaka, S., Atarashi, K., Nakamoto, N., Iwata, S., Honda, K., Kanai, T., Hasegawa, N., Koyasu, S. & Betsuyaku, T., 2018 Apr 1, In : PLoS Pathogens. 14, 4, e1006955.

Research output: Contribution to journalArticle

Bacterial Pneumonia
Clarithromycin
Septic Shock
Human Influenza
Pneumococcal Pneumonia

Clinical characteristics of pulmonary Mycobacterium lentiflavum disease in adult patients

Yagi, K., Morimoto, K., Ishii, M., Namkoong, H., Okamori, S., Asakura, T., Suzuki, S., Asami, T., Uwamino, Y., Funatsu, Y., Fujiwara, H., Kamata, H., Nishimura, T., Betsuyaku, T., Kurashima, A. & Hasegawa, N., 2018 Feb 1, In : International Journal of Infectious Diseases. 67, p. 65-69 5 p.

Research output: Contribution to journalArticle

Mycobacterium
Lung
Medical Records
Thorax
Tomography
2 Citations (Scopus)

Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients

Sakurai, K., Chubachi, S., Irie, H., Tsutsumi, A., Kameyama, N., Kamatani, T., Koh, H., Terashima, T., Nakamura, H., Asano, K. & Betsuyaku, T., 2018 May 2, In : BMC Pulmonary Medicine. 18, 1, 65.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Neutrophils
Lymphocytes
Respiratory Function Tests
ROC Curve
3 Citations (Scopus)

Comparison of detection methods of EGFR T790M mutations using plasma, serum, and tumor tissue in EGFR-TKI-resistant non-small cell lung cancer

Kobayashi, K., Naoki, K., Manabe, T., Masuzawa, K., Hasegawa, H., Yasuda, H., Kawada, I., Soejima, K. & Betsuyaku, T., 2018 Jun 6, In : OncoTargets and Therapy. 11, p. 3335-3343 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Biopsy
Mutation
Serum
Neoplasms

Development of lung cancer in patients with; nontuberculous mycobacterial lung disease

Kusumoto, T., Asakura, T., Suzuki, S., Okamori, S., Namkoong, H., Fujiwara, H., Yagi, K., Kamata, H., Ishii, M., Betsuyaku, T. & Hasegawa, N., 2018 Jan 1, (Accepted/In press) In : Respiratory Investigation.

Research output: Contribution to journalArticle

Lung Diseases
Lung Neoplasms
Mycobacterium avium Complex
Registries
Thorax
2 Citations (Scopus)

Development of necrotizing myopathy following interstitial lung disease with anti-signal recognition particle antibody

Kusumoto, T., Okamori, S., Masuzawa, K., Asakura, T., Nishina, N., Chubachi, S., Naoki, K., Fukunaga, K. & Betsuyaku, T., 2018 Jan 1, In : Internal Medicine. 57, 14, p. 2045-2049 5 p.

Research output: Contribution to journalArticle

Signal Recognition Particle
Interstitial Lung Diseases
Muscular Diseases
Creatinine
Phosphotransferases
8 Citations (Scopus)

Effects of long-term cigarette smoke exposure on bone metabolism, structure, and quality in a mouse model of emphysema

Sasaki, M., Chubachi, S., Kameyama, N., Sato, M., Haraguchi, M., Miyazaki, M., Takahashi, S., Nakano, T., Kuroda, Y., Betsuyaku, T. & Matsuo, K., 2018 Jan 1, In : PLoS One. 13, 1, e0191611.

Research output: Contribution to journalArticle

bone metabolism
cigarettes
Emphysema
smoke
Metabolism
1 Citation (Scopus)

Efficacy and safety of intermittent maintenance therapy after successful treatment of Mycobacterium avium complex lung disease

Nontuberculous Mycobacteriosis Japan Research Consortium (NTM-JRC), 2018 Jan 1, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Lung Diseases
Safety
Therapeutics
Recurrence

Egfr-mutant non-small cell lung cancer accompanied by transient asymptomatic pulmonary opacities successfully treated with “stop-and-go” osimertinib

Kobayashi, K., Naoki, K., Kuroda, A., Yasuda, H., Kawada, I., Soejima, K. & Betsuyaku, T., 2018 Jan 1, In : Internal Medicine. 57, 7, p. 1007-1010 4 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung
Epidermal Growth Factor Receptor
Tomography
Interstitial Lung Diseases

Eosinophils and anti-inflammatory lipid mediators

Fukunaga, K., 2018 Jan 1, In : Japanese Journal of Allergology. 67, 1, p. 28-30 3 p.

Research output: Contribution to journalArticle

Eosinophils
Anti-Inflammatory Agents
Lipids
3 Citations (Scopus)

Health-related QOL of elderly patients with pulmonary M. avium complex disease in a university hospital

Asakura, T., Ishii, M., Ishii, K., Suzuki, S., Namkoong, H., Okamori, S., Kamata, H., Yagi, K., Funatsu, Y., Betsuyaku, T. & Hasegawa, N., 2018 Jun 1, In : International Journal of Tuberculosis and Lung Disease. 22, 6, p. 695-703 9 p.

Research output: Contribution to journalArticle

Mycobacterium avium Complex
Quality of Life
Lung
Health
Cross-Sectional Studies
2 Citations (Scopus)

High fat diet activates adult mouse lung stem cells and accelerates several aging-induced effects

Hegab, A. E., Ozaki, M., Meligy, F. Y., Kagawa, S., Ishii, M. & Betsuyaku, T., 2018 Dec 1, In : Stem Cell Research. 33, p. 25-35 11 p.

Research output: Contribution to journalArticle

High Fat Diet
Stem Cells
Lung
Organoids
Alveolar Epithelial Cells
2 Citations (Scopus)

Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort

On behalf of the Keio COPD Comorbidity Research (K-CCR) Group, 2018 Nov 1, In : Chronic Respiratory Disease. 15, 4, p. 329-338 10 p.

Research output: Contribution to journalArticle

Cataract
Chronic Obstructive Pulmonary Disease
Quality of Life
Lung
Comorbidity
5 Citations (Scopus)

Intermittent exposure to cigarette smoke increases lung tumors and the severity of emphysema more than continuous exposure

Kameyama, N., Chubachi, S., Hegab, A. E., Yasuda, H., Kagawa, S., Tsutsumi, A., Fukunaga, K., Shimoda, M., Kanai, Y., Soejima, K. & Betsuyaku, T., 2018 Aug 1, In : American Journal of Respiratory Cell and Molecular Biology. 59, 2, p. 179-188 10 p.

Research output: Contribution to journalArticle

Emphysema
Smoke
Tobacco Products
Tumors
Lung
5 Citations (Scopus)

Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: A case report with microbiological analysis

Okamori, S., Asakura, T., Nishimura, T., Tamizu, E., Ishii, M., Yoshida, M., Fukano, H., Hayashi, Y., Fujita, M., Hoshino, Y., Betsuyaku, T. & Hasegawa, N., 2018 Jan 2, In : BMC Infectious Diseases. 18, 1, 1.

Research output: Contribution to journalArticle

Mycobacterium fortuitum
Natural History
Lung
Infection
Pneumonia
5 Citations (Scopus)

Pharmacological and structural characterizations of naquotinib, a novel third-generation EGFR tyrosine kinase inhibitor, in EGFR-mutated non–small cell lung cancer

Hirano, T., Yasuda, H., Hamamoto, J., Nukaga, S., Masuzawa, K., Kawada, I., Naoki, K., Niimi, T., Mimasu, S., Sakagami, H., Soejima, K. & Betsuyaku, T., 2018 Apr 1, In : Molecular Cancer Therapeutics. 17, 4, p. 740-750 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Pharmacology
Exons
5 Citations (Scopus)

Plasma sE-cadherin and the plasma sE-cadherin/sVE-cadherin ratio are potential biomarkers for chronic obstructive pulmonary disease

Shirahata, T., Nakamura, H., Nakajima, T., Nakamura, M., Chubachi, S., Yoshida, S., Tsuduki, K., Mashimo, S., Takahashi, S., Minematsu, N., Tateno, H., Asano, K., Fujishima, S. & Betsuyaku, T., 2018 Feb 12, (Accepted/In press) In : Biomarkers. p. 1-8 8 p.

Research output: Contribution to journalArticle

Pulmonary diseases
Biomarkers
Cadherins
Chronic Obstructive Pulmonary Disease
Plasmas
5 Citations (Scopus)

Prevalence and clinical characteristics of obstructive- and central-dominant sleep apnea in candidates of catheter ablation for atrial fibrillation in Japan

Kohno, T., Kimura, T., Fukunaga, K., Yamasawa, W., Fujisawa, T., Fukuoka, R., Nakajima, K., Kashimura, S., Kunitomi, A., Katsumata, Y., Nishiyama, T., Nishiyama, N., Aizawa, Y., Fukuda, K. & Takatsuki, S., 2018 Jun 1, In : International Journal of Cardiology. 260, p. 99-102 4 p.

Research output: Contribution to journalArticle

Central Sleep Apnea
Catheter Ablation
Atrial Fibrillation
Sleep Apnea Syndromes
Japan

Prognostic Understanding at Diagnosis and Associated Factors in Patients with Advanced Lung Cancer and Their Caregivers

Sato, T., Soejima, K., Fujisawa, D., Takeuchi, M., Arai, D., Nakachi, I., Naoki, K., Kawada, I., Yasuda, H., Ishioka, K., Nukaga, S., Kobayashi, K., Masaki, K., Inoue, T., Hikima, K., Nakamura, M., Ohgino, K., Oyamada, Y., Funatsu, Y., Terashima, T. & 5 others, Miyao, N., Sayama, K., Saito, F., Sakamaki, F. & Betsuyaku, T., 2018 Jan 1, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Caregivers
Lung Neoplasms
Anxiety
Depression
Neoplasms
1 Citation (Scopus)

Pulmonary nocardiosis mimicking small cell lung cancer in ectopic ACTH syndrome associated with transformation of olfactory neuroblastoma: A case report

Kobayashi, K., Asakura, T., Ishii, M., Ueda, S., Irie, H., Ozawa, H., Saitoh, K., Kurihara, I., Itoh, H. & Betsuyaku, T., 2018 Aug 22, In : BMC Pulmonary Medicine. 18, 1, 142.

Research output: Contribution to journalArticle

Paraneoplastic Endocrine Syndromes
Olfactory Esthesioneuroblastoma
Nocardia Infections
Small Cell Lung Carcinoma
Adrenocorticotropic Hormone