Department of Internal Medicine (Rheumatology)

Research Output 1997 2019

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2019

Antigen-driven selection of antibodies against SSA, SSB and the centromere 'complex', including a novel antigen, MIS12 complex, in human salivary glands

Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., Kato, S., Tsunoda, K., Arase, H. & Takeuchi, T., 2019 Jan 1, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Open Access
Centromere
Salivary Glands
Autoantibodies
Antigens
Anti-Idiotypic Antibodies
Systemic Scleroderma
Autoantibodies
Hand
X-Rays
Acro-Osteolysis
Giant Cell Arteritis
Body Mass Index
Recurrence

Clinical characteristics of patients with spondyloarthritis in Japan in comparison with other regions of the world

Kishimoto, M., Yoshida, K., Ichikawa, N., Inoue, H., Kaneko, Y., Kawasaki, T., Matsui, K., Morita, M., Suda, M., Tada, K., Takizawa, N., Tamura, N., Taniguchi, A., Taniguchi, Y., Tsuji, S., Haji, Y., Rokutanda, R., Yanaoka, H., Cheung, P. P., Gu, J. & 9 others, Kim, T. H., Luo, S. F., Okada, M., Medina, C. L., Molto, A., Dougados, M., Kobayashi, S., Van Der Heijde, D. & Tomita, T., 2019 Aug 1, In : Journal of Rheumatology. 46, 8, p. 896-903 8 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Ankylosing Spondylitis
Japan
HLA-B27 Antigen
Comorbidity

Clinicopathological features of clinical methotrexate-related lymphoproliferative disorders

Tokuhira, M., Saito, S., Suzuki, K., Higashi, M., Momose, S., Shimizu, T., Mori, T., Kimura, Y., Amano, K., Okamoto, S., Takeuchi, T., Tamaru, J. I. & Kizaki, M., 2019 Jan 1, In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
Methotrexate
Autoimmune Diseases
Interleukin-2 Receptors
Hodgkin Disease
2 Citations (Scopus)
Leukemia, Myeloid, Chronic Phase
Protein-Tyrosine Kinases
Registries
Safety
Disease-Free Survival

IgG4-Related Disease: A Growing Appreciation of Follicular Helper T Cell Expansion

Akiyama, M., Suzuki, K., Kaneko, Y. & Takeuchi, T., 2019 Sep 1, In : Clinical and translational gastroenterology. 10, 9, p. e00076

Research output: Contribution to journalArticle

Open Access
Helper-Inducer T-Lymphocytes
Immunoglobulin G

Multi-dimensional analysis identified rheumatoid arthritis-driving pathway in human T cell

Takeshita, M., Suzuki, K., Kondo, Y., Morita, R., Okuzono, Y., Koga, K., Kassai, Y., Gamo, K., Takiguchi, M., Kurisu, R., Mototani, H., Ebisuno, Y., Yoshimura, A. & Takeuchi, T., 2019 Jan 1, In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

T-cells
Rheumatoid Arthritis
T-Lymphocytes
Genes
Synovial Fluid

Predictive value of serum amyloid a levels for requirement of concomitant methotrexate in tocilizumab initiation: A post hoc analysis of the SURPRISE study

Kato, M., Kaneko, Y., Tanaka, Y., Inoo, M., Kobayashi-Haraoka, H., Amano, K., Miyata, M., Murakawa, Y., Yasuoka, H., Hirata, S., Nagasawa, H., Tanaka, E., Miyasaka, N., Yamanaka, H., Yamamoto, K., Yokota, I., Atsumi, T. & Takeuchi, T., 2019 Jan 1, In : Modern Rheumatology.

Research output: Contribution to journalArticle

Amyloid
Methotrexate
Serum
Rheumatoid Arthritis
Area Under Curve
2 Citations (Scopus)

Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis

Kondo, Y., Suzuki, K., Inoue, Y., Sakata, K., Takahashi, C., Takeshita, M., Kassai, Y., Miyazaki, T., Morita, R., Niki, Y., Kaneko, Y., Yasuoka, H., Yamaoka, K., Yoshimura, A. & Takeuchi, T., 2019 Oct 1, In : Arthritis Research and Therapy. 21, 1, 14.

Research output: Contribution to journalArticle

Ultrasonography
Rheumatoid Arthritis
Joints
Synovitis
Synovial Membrane
Granulomatosis with Polyangiitis
Rheumatoid Factor
Antineutrophil Cytoplasmic Antibodies
Eosinophils
Musculoskeletal Diseases

Sustained discontinuation of infliximab with a raising-dose strategy after obtaining remission in patients with rheumatoid arthritis: The RRRR study, a randomised controlled trial

Tanaka, Y., Oba, K., Koike, T., Miyasaka, N., Mimori, T., Takeuchi, T., Hirata, S., Tanaka, E., Yasuoka, H., Kaneko, Y., Murakami, K., Koga, T., Nakano, K., Amano, K., Ushio, K., Atsumi, T., Inoo, M., Hatta, K., Mizuki, S., Nagaoka, S. & 4 others, Tsunoda, S., Dobashi, H., Horie, N. & Sato, N., 2019 Jan 1, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Open Access
Rheumatoid Arthritis
Randomized Controlled Trials
Infliximab
Tumor Necrosis Factor-alpha
Therapeutics

The development of quality indicators for systemic lupus erythematosus using electronic health data: A modified RAND appropriateness method

Yajima, N., Tsujimoto, Y., Fukuma, S., Sada, K. E., Shimizu, S., Niihata, K., Takahashi, R., Asano, Y., Azuma, T., Kameda, H., Kuwana, M., Kohsaka, H., Sugiura-Ogasawara, M., Suzuki, K., Takeuchi, T., Tanaka, Y., Tamura, N., Matsui, T., Mimori, T., Fukuhara, S. & 1 others, Atsumi, T., 2019 Jan 1, In : Modern Rheumatology.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Health
Medical Electronics
Drug Monitoring
Quality of Health Care

Usefulness of serum Krebs von den Lungen-6 for the management of myositis-associated interstitial lung disease

Takanashi, S., Nishina, N., Nakazawa, M., Kaneko, Y. & Takeuchi, T., 2019 Jun 1, In : Rheumatology (Oxford, England). 58, 6, p. 1034-1039 6 p.

Research output: Contribution to journalArticle

Myositis
Interstitial Lung Diseases
Serum
Recurrence
Biomarkers
2018
2 Citations (Scopus)

Adolescent PR3-ANCA-positive hypertrophic pachymeningitis

Matsumoto, K., Akiyama, M., Kajio, N., Otomo, K., Suzuki, K., Nishina, N., Kasuya, K., Oishi, N., Kameyama, K. & Takeuchi, T., 2018 Apr 1, In : Medicine (United States). 97, 17, e0521.

Research output: Contribution to journalArticle

Myeloblastin
Antineutrophil Cytoplasmic Antibodies
Meningitis
Immunosuppressive Agents
Prednisolone
4 Citations (Scopus)
Phase III Clinical Trials
Rheumatoid Arthritis
Joints
Physicians
Pain Measurement
2 Citations (Scopus)

Development of necrotizing myopathy following interstitial lung disease with anti-signal recognition particle antibody

Kusumoto, T., Okamori, S., Masuzawa, K., Asakura, T., Nishina, N., Chubachi, S., Naoki, K., Fukunaga, K. & Betsuyaku, T., 2018 Jan 1, In : Internal Medicine. 57, 14, p. 2045-2049 5 p.

Research output: Contribution to journalArticle

Signal Recognition Particle
Interstitial Lung Diseases
Muscular Diseases
Creatinine
Phosphotransferases

Effectiveness of tacrolimus on IgG4-related disease

Takanashi, S., Kaneko, Y. & Takeuchi, T., 2018 Jan 1, (Accepted/In press) In : Modern Rheumatology.

Research output: Contribution to journalArticle

Tacrolimus
Immunoglobulin G
3 Citations (Scopus)

Effect of subcutaneous tocilizumab treatment on work/housework status in biologic-naïve rheumatoid arthritis patients using inverse probability of treatment weighting: FIRST ACT-SC study

Tanaka, Y., Kameda, H., Saito, K., Kaneko, Y., Tanaka, E., Yasuda, S., Tamura, N., Fujio, K., Fujii, T., Kojima, T., Anzai, T., Hamada, C., Fujino, Y., Matsuda, S. & Kohsaka, H., 2018 Jul 20, In : Arthritis Research and Therapy. 20, 1, 151.

Research output: Contribution to journalArticle

Housekeeping
Biological Products
Rheumatoid Arthritis
Antirheumatic Agents
Quality of Life

Factors predicting the therapeutic response to methotrexate in Japanese patients with rheumatoid arthritis: A hospital-based cohort study

Hakamata, J., Kaneko, Y., Shimizu, M., Yamaoka, K., Maruyama, J., Takeuchi, T., Mochizuki, M. & Hashiguchi, M., 2018 Jan 1, In : Biological and Pharmaceutical Bulletin. 41, 9, p. 1414-1422 9 p.

Research output: Contribution to journalArticle

Methotrexate
Rheumatoid Arthritis
Cohort Studies
Therapeutics
Genotype
5 Citations (Scopus)

IgG4-related fibrosing mediastinitis diagnosed with computed tomography-guided percutaneous needle biopsy

Takanashi, S., Akiyama, M., Suzuki, K., Otomo, K. & Takeuchi, T., 2018 Jun 1, In : Medicine (United States). 97, 22, e10935.

Research output: Contribution to journalArticle

Needle Biopsy
Immunoglobulin G
Tomography
Immunoglobulins
Fibrosis
1 Citation (Scopus)
Synovitis
Ankle
Foot
Ultrasonography
Rheumatoid Arthritis
1 Citation (Scopus)
Monocytes
Interleukin-6
Rheumatoid Arthritis
Tumor Necrosis Factor-alpha
Methotrexate
2 Citations (Scopus)

Inflammatory tenosynovitis and enthesitis induced by immune checkpoint inhibitor treatment

Inamo, J., Kaneko, Y. & Takeuchi, T., 2018 Feb 17, (Accepted/In press) In : Clinical Rheumatology. p. 1-4 4 p.

Research output: Contribution to journalArticle

Tenosynovitis
Joints
Arthralgia
Therapeutics
Arthritis
6 Citations (Scopus)

Initial predictors of poor survival in myositisassociated interstitial lung disease: A multicentre cohort of 497 patients

A Multicentre Retrospective Cohort of Japanese Patients with Myositis-associated ILD Investigators, 2018 Jul 1, In : Rheumatology (United Kingdom). 57, 7, p. 1212-1221 10 p.

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Survival
Mortality
Age of Onset
Autoantibodies
Centromere
Anti-Idiotypic Antibodies
Autoimmune Diseases
Cholangitis
Systemic Scleroderma
9 Citations (Scopus)

Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission

Tasaki, S., Suzuki, K., Kassai, Y., Takeshita, M., Murota, A., Kondo, Y., Ando, T., Nakayama, Y., Okuzono, Y., Takiguchi, M., Kurisu, R., Miyazaki, T., Yoshimoto, K., Yasuoka, H., Yamaoka, K., Morita, R., Yoshimura, A., Toyoshiba, H. & Takeuchi, T., 2018 Dec 1, In : Nature Communications. 9, 1, 2755.

Research output: Contribution to journalArticle

Drug therapy
arthritis
Drug Monitoring
Rheumatoid Arthritis
drugs

Persistent fever and destructive arthritis caused by dialysis-related amyloidosis

Matsumoto, K., Kikuchi, J., Kaneko, Y., Yasuoka, H., Suzuki, K., Tokuyama, H., Kameyama, K., Yamaoka, K. & Takeuchi, T., 2018 Jan 1, In : Medicine (United States). 97, 1, 9359.

Research output: Contribution to journalArticle

Amyloidosis
Arthritis
Dialysis
Fever
Renal Dialysis
4 Citations (Scopus)

Residual symptoms and disease burden among patients with rheumatoid arthritis in remission or low disease activity: a systematic literature review

Ishida, M., Kuroiwa, Y., Yoshida, E., Sato, M., Krupa, D., Henry, N., Ikeda, K. & Kaneko, Y., 2018 Jan 11, (Accepted/In press) In : Modern Rheumatology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Fatigue
Publications
Mental Health
Sleep

Response to: 'Some concerns from Turkey' by Bilgin et al

Kaneko, Y., Kameda, H., Ikeda, K., Ishii, T., Murakami, K., Takamatsu, H., Tanaka, Y., Abe, T. & Takeuchi, T., 2018 Jan 1, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Non-Steroidal Anti-Inflammatory Agents
Turkey
1 Citation (Scopus)

Response to e-letter: 'Tocilizumab in patients with adult-onset Still's disease refractory to glucocorticoid treatment' by Lee

Kaneko, Y., Kameda, H., Ikeda, K., Ishii, T., Murakami, K., Takamatsu, H., Tanaka, Y., Abe, T. & Takeuchi, T., 2018 Jan 1, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Adult-Onset Still's Disease
Refractory materials
Glucocorticoids
Cytokines
Therapeutics
1 Citation (Scopus)

Restoration of decreased T helper 1 and CD8+ T cell subsets is associated with regression of lymphoproliferative disorders developed during methotrexate treatment

Saito, S., Suzuki, K., Yoshimoto, K., Kaneko, Y., Yamaoka, K., Shimizu, T., Mori, T., Okamoto, S., Kameyama, K., Amano, K., Tamaru, J. I., Tokuhira, M. & Takeuchi, T., 2018 Apr 4, In : Frontiers in Immunology. 9, APR, 621.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
T-Lymphocyte Subsets
Methotrexate
Th1 Cells
T-Lymphocytes
6 Citations (Scopus)

Risk factors of relapse following glucocorticoid tapering in IgG4-related disease

Sasaki, T., Akiyama, M., Kaneko, Y., Yasuoka, H., Suzuki, K., Yamaoka, K. & Takeuchi, T., 2018 Jan 1, In : Clinical and Experimental Rheumatology. 36, p. S186-S189

Research output: Contribution to journalArticle

Glucocorticoids
Immunoglobulin G
Recurrence
Serum
Immunoglobulin A
5 Citations (Scopus)
Interleukin-2 Receptors
Differential Diagnosis
Immunoglobulin G
Biomarkers
Serum
Observation
Rheumatoid Factor
Immunologic Factors
Immunoglobulin G
Thrombocytopenia
9 Citations (Scopus)

Tocilizumab discontinuation after attaining remission in patients with rheumatoid arthritis who were treated with tocilizumab alone or in combination with methotrexate: Results from a prospective randomised controlled study (the second year of the SURPRISE study)

Kaneko, Y., Kato, M., Tanaka, Y., Inoo, M., Kobayashi-Haraoka, H., Amano, K., Miyata, M., Murakawa, Y., Yasuoka, H., Hirata, S., Tanaka, E., Miyasaka, N., Yamanaka, H., Yamamoto, K. & Takeuchi, T., 2018 May 26, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Methotrexate
Rheumatoid Arthritis
tocilizumab
Antirheumatic Agents
Retreatment
10 Citations (Scopus)

Tocilizumab in patients with adult-onset still's disease refractory to glucocorticoid treatment: A randomised, double-blind, placebo-controlled phase III trial

Kaneko, Y., Kameda, H., Ikeda, K., Ishii, T., Murakami, K., Takamatsu, H., Tanaka, Y., Abe, T. & Takeuchi, T., 2018 Jan 1, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Adult-Onset Still's Disease
Refractory materials
Glucocorticoids
Placebos
Therapeutics
2017

[No title available]

Hasegawa, T., Kaneko, Y., Izumi, K. & Takeuchi, T., 2017, (Accepted/In press) In : Revue du Rhumatisme (Edition Francaise).

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Denosumab
4 Citations (Scopus)

A new bioassay for measuring the strength of IL-6/STAT3 signal inhibition by tocilizumab in patients with rheumatoid arthritis

Saito, S., Suzuki, K., Yoshimoto, K., Kaneko, Y., Matsumoto, Y., Yamaoka, K. & Takeuchi, T., 2017 Oct 17, In : Arthritis Research and Therapy. 19, 1

Research output: Contribution to journalArticle

Biological Assay
Interleukin-6
Rheumatoid Arthritis
Phosphorylation
T-Lymphocytes
19 Citations (Scopus)

Association of erythrocyte methotrexate-polyglutamate levels with the efficacy and hepatotoxicity of methotrexate in patients with rheumatoid arthritis: A 76-week prospective study

Takahashi, C., Kaneko, Y., Okano, Y., Taguchi, H., Oshima, H., Izumi, K., Yamaoka, K. & Takeuchi, T., 2017 Jan 1, In : RMD Open. 3, 1, e000363.

Research output: Contribution to journalArticle

Methotrexate
Rheumatoid Arthritis
Erythrocytes
Prospective Studies
Transaminases
20 Citations (Scopus)

CD14brightCD16+ intermediate monocytes are induced by interleukin-10 and positively correlate with disease activity in rheumatoid arthritis

Tsukamoto, M., Seta, N., Yoshimoto, K., Suzuki, K., Yamaoka, K. & Takeuchi, T., 2017 Feb 10, In : Arthritis Research and Therapy. 19, 1, 28.

Research output: Contribution to journalArticle

Interleukin-10
Monocytes
Rheumatoid Arthritis
Interleukin-8
Cytokines
10 Citations (Scopus)

Clinicopathologic investigation of methotrexate-induced lymphoproliferative disorders, with a focus on regression

Tokuhira, M., Saito, S., Okuyama, A., Suzuki, K., Higashi, M., Momose, S., Shimizu, T., Mori, T., Anan-Nemoto, T., Amano, K., Okamoto, S., Takeuchi, T., Tamaru, J. I. & Kizaki, M., 2017 Sep 7, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-10 10 p.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
Methotrexate
Virus Diseases
Recurrence
Survival
1 Citation (Scopus)
Pneumocystis Pneumonia
Biological Products
Rheumatoid Arthritis
Lymphocytes
Lymphocyte Count
8 Citations (Scopus)

Distinct features distinguishing IgG4-related disease from multicentric Castleman's disease

Sasaki, T., Akiyama, M., Kaneko, Y., Mori, T., Yasuoka, H., Suzuki, K., Yamaoka, K., Okamoto, S. & Takeuchi, T., 2017 Jul 1, In : RMD Open. 3, 1, e000432.

Research output: Contribution to journalArticle

Immunoglobulin G
C-Reactive Protein
Immunoglobulin A
Lacrimal Apparatus
History
13 Citations (Scopus)

Distinct patterns of lymphocyte count transition in lymphoproliferative disorder in patients with rheumatoid arthritis treated with methotrexate

Saito, S., Kaneko, Y., Yamaoka, K., Tokuhira, M. & Takeuchi, T., 2017 Jun 1, In : Rheumatology (United Kingdom). 56, 6, p. 940-946 7 p., kex002.

Research output: Contribution to journalArticle

Lymphoproliferative Disorders
Lymphocyte Count
Methotrexate
Rheumatoid Arthritis
Control Groups
3 Citations (Scopus)

Effect of genetic polymorphisms of azathioprine-metabolizing enzymes on response to rheumatoid arthritis treatment

Tsuchiya, A., Aomori, T., Sakamoto, M., Takeuchi, A., Suzuki, S., Jibiki, A., Otsuka, N., Ishioka, E., Kaneko, Y., Takeuchi, T. & Nakamura, T., 2017, In : Pharmazie. 72, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

Azathioprine
Genetic Polymorphisms
Rheumatoid Arthritis
Genotype
Enzymes
2 Citations (Scopus)

Efficacy and tolerability of six-week extended dosing interval with tocilizumab therapy in a prospective cohort as remission maintenance in patients with rheumatoid arthritis

Kikuchi, J., Kondo, T., Shibata, A., Sakai, R., Okada, Y., Chino, K., Okuyama, A., Kurasawa, T., Takei, H. & Amano, K., 2017 Aug 29, (Accepted/In press) In : Modern Rheumatology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Blood Sedimentation
Rheumatoid Arthritis
Maintenance
Therapeutics
Lymphoproliferative Disorders
4 Citations (Scopus)

Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

Sakamoto, Y., Yamamoto, T., Sugano, N., Takahashi, D., Watanabe, T., Atsumi, T., Nakamura, J., Hasegawa, Y., Akashi, K., Narita, I., Miyamoto, T., Takeuchi, T., Ikari, K., Amano, K., Fujie, A., Kubo, T., Tada, Y., Kaneuji, A., Nakamura, H., Miyamura, T. & 70 others, Kabata, T., Yamaji, K., Okawa, T., Sudo, A., Ohzono, K., Tanaka, Y., Yasunaga, Y., Matsuda, S., Imai, Y., Nakashima, Y., Motomura, G., Ikemura, S., Yamaguchi, R., Karasuyama, K., Sonoda, K., Nishii, T., Sakai, T., Takao, M., Irie, T., Asano, T., Iwasaki, N., Atsumi, T., Tamaoki, S., Nakanishi, R., Tanabe, S., Kishida, S., Hagiwara, S., Seki, T., Tsukamoto, H., Niiro, H., Arinobu, Y., Akahoshi, M., Mitoma, H., Ayano, M., Kuroda, T., Toyama, Y., Funayama, A., Hanaoka, H., Yamaoka, K., Kawaguchi, Y., Yamanaka, H., Hosozawa, T., Momohara, S., Chino, K., Fujioka, M., Ueshima, K., Ishida, M., Saito, M., Hayashi, S., Ikegami, A., Ichiseki, T., Mizokawa, S., Ohta, Y., Kajino, Y., Sekiya, F., Higuchi, F., Hasegawa, M., Miyamoto, N., Miyazaki, S., Yamaguchi, T., Ando, W., Saito, K., Nakano, K., Kuroda, Y., Yamasaki, T., Akiyama, M., Kubo, M., Kamatani, Y., Iwamoto, Y. & Ikegawa, S., 2017 Dec 1, In : Scientific Reports. 7, 1, 15035.

Research output: Contribution to journalArticle

Osteonecrosis
Genome-Wide Association Study
Thigh
Hip Joint
Drinking
3 Citations (Scopus)

Importance of obtaining remission for work productivity and activity of patients with rheumatoid arthritis

Kim, D., Kaneko, Y. & Takeuchi, T., 2017 Aug 1, In : Journal of Rheumatology. 44, 8, p. 1112-1117 6 p.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Efficiency
Linear Models
Regression Analysis
Pain
2 Citations (Scopus)

Increased proportion of a CD38highIgD+ B cell subset in peripheral blood is associated with clinical and immunological features in patients with primary Sjögren's syndrome

Ishioka-Takei, E., Yoshimoto, K., Suzuki, K., Nishikawa, A., Yasuoka, H., Yamaoka, K. & Takeuchi, T., 2017, (Accepted/In press) In : Clinical Immunology.

Research output: Contribution to journalArticle

B-Lymphocyte Subsets
B-Lymphocytes
Immunoglobulin G
Serum
Autoantibodies