• 39852 Citations
  • 104 h-Index
1982 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Review article
2020

Regulatory T cells: Pathophysiological roles and clinical applications

Sakai, R., Komai, K., Iizuka-Koga, M., Yoshimura, A. & Ito, M., 2020 Jan 1, In : Keio Journal of Medicine. 69, 1, p. 1-15 15 p.

Research output: Contribution to journalReview article

Open Access
2019

Memory T cell, exhaustion, and tumor immunity

Ando, M., Ito, M., Srirat, T., Kondo, T. & Yoshimura, A., 2019 Jan 1, (Accepted/In press) In : Immunological Medicine.

Research output: Contribution to journalReview article

Open Access
2018

Development and Functional Modulation of Regulatory T Cells by Transcription Factors and Epigenetics

Ito, M., Iizuka-Koga, M., Ando, M. & Yoshimura, A., 2018 Nov 1, In : Cornea. 37, p. S42-S49

Research output: Contribution to journalReview article

1 Citation (Scopus)

Pivotal role of innate myeloid cells in cerebral post-ischemic sterile inflammation

Tsuyama, J., Nakamura, A., Ooboshi, H., Yoshimura, A. & Shichita, T., 2018 Nov 1, In : Seminars in Immunopathology. 40, 6, p. 523-538 16 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

The mechanism underlying the resolution of sterile inflammation through scavenger receptor

Shchita, T. & Yoshimura, A., 2018 Jan 1, In : Seikagaku. 90, 1, p. 99-102 4 p.

Research output: Contribution to journalReview article

2017

Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications

Iizuka-Koga, M., Nakatsukasa, H., Ito, M., Akanuma, T., Lu, Q. & Yoshimura, A., 2017 Sep 1, In : Journal of Autoimmunity. 83, p. 113-121 9 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy

Chikuma, S., Kanamori, M., Mise-Omata, S. & Yoshimura, A., 2017 Apr 1, In : Cancer Science. 108, 4, p. 574-580 7 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)
2016

Induced Regulatory T Cells: Their Development, Stability, and Applications

Kanamori, M., Nakatsukasa, H., Okada, M., Lu, Q. & Yoshimura, A., 2016 Nov 1, In : Trends in Immunology. 37, 11, p. 803-811 9 p.

Research output: Contribution to journalReview article

82 Citations (Scopus)
2014

SOCS1 and regulation of regulatory T cells plasticity

Takahashi, R. & Yoshimura, A., 2014 Jan 1, In : Journal of immunology research. 2014, 943149.

Research output: Contribution to journalReview article

17 Citations (Scopus)
2013

[Peroxiredoxin triggers post-ischemic inflammation].

Yoshimura, A., Ito, M., Kondo, T. & Shichita, T., 2013 Mar, In : Unknown Journal. 85, 3, p. 179-186 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

[Post-ischemic innate immunity and its application for novel therapeutic strategy targeting brain inflammation].

Ito, M., Kondo, T., Shichita, T. & Yoshimura, A., 2013 Jul, In : Unknown Journal. 71, 7, p. 1291-1301 11 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
2012

Post-ischemic inflammation in the brain

Shichita, T., Sakaguchi, R., Suzuki, M. & Yoshimura, A., 2012 Dec 1, In : Frontiers in Immunology. 3, MAY, Article 132.

Research output: Contribution to journalReview article

116 Citations (Scopus)

SOCS, inflammation, and autoimmunity

Yoshimura, A., Suzuki, M., Sakaguchi, R., Hanada, T. & Yasukawa, H., 2012 Dec 1, In : Frontiers in Immunology. 3, MAR, Article 20.

Research output: Contribution to journalReview article

139 Citations (Scopus)
2011

[Suppression of leptin and insulin signaling by SOCS3].

Yoshimura, A., 2011 Jan 1, In : Nihon rinsho. Japanese journal of clinical medicine. 69 Suppl 1, p. 782-789 8 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
2010

Cellular and molecular basis for the regulation of inflammation by TGF-β

Yoshimura, A., Wakabayashi, Y. & Mori, T., 2010 Jun 1, In : Journal of biochemistry. 147, 6, p. 781-792 12 p.

Research output: Contribution to journalReview article

211 Citations (Scopus)
2009

Regulation of cytokine signaling by the SOCS and Spred family proteins

Yoshimura, A., 2009 Jun 1, In : Keio Journal of Medicine. 58, 2, p. 73-83 11 p.

Research output: Contribution to journalReview article

62 Citations (Scopus)
2007

Intracellular negative signals and allergy

Yoshimura, A., Tanaka, K., Okamoto, F. & Kobayashi, T., 2007 Jun, In : Arerugī = [Allergy]. 56, 6, p. 563-569 7 p.

Research output: Contribution to journalReview article

Role of endogenous inhibitors of cytokine signaling in allergic asthma

Inoue, H., Fukuyama, S., Matsumoto, K., Kubo, M. & Yoshimura, A., 2007 Jan 1, In : Current Medicinal Chemistry. 14, 2, p. 181-189 9 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

SOCS proteins, cytokine signalling and immune regulation

Yoshimura, A., Naka, T. & Kubo, M., 2007 Jun 1, In : Nature Reviews Immunology. 7, 6, p. 454-465 12 p.

Research output: Contribution to journalReview article

987 Citations (Scopus)
2006

Signal transduction of inflammatory cytokines and tumor development

Yoshimura, A., 2006 Jun 1, In : Cancer science. 97, 6, p. 439-447 9 p.

Research output: Contribution to journalReview article

223 Citations (Scopus)
2005

Negative regulation of cytokine and TLR signalings by SOCS and others

Naka, T., Fujimoto, M., Tsutsui, H. & Yoshimura, A., 2005 Aug 24, In : Advances in Immunology. 87, p. 61-122 62 p.

Research output: Contribution to journalReview article

78 Citations (Scopus)

Negative regulation of cytokine signaling

Yoshimura, A., 2005 Jun 1, In : Clinical Reviews in Allergy and Immunology. 28, 3, p. 205-220 16 p.

Research output: Contribution to journalReview article

43 Citations (Scopus)

Negative regulation of cytokine signaling and immune responses by SOCS proteins

Yoshimura, A., Nishinakamura, H., Matsumura, Y. & Hanada, T., 2005 Jun 1, In : Arthritis Research and Therapy. 7, 3, p. 100-110 11 p.

Research output: Contribution to journalReview article

112 Citations (Scopus)

Receptor tyrosine kinases (c-kit, c-fmns, Flt-3, Tie2, etc.)

Yoshimura, A., Sanada, M. & Mashima, R., 2005 Apr, In : Nippon rinsho. Japanese journal of clinical medicine. 63 Suppl 4, p. 207-214 8 p.

Research output: Contribution to journalReview article

2004

Membrane dynamics and cell signaling as studied by single molecule imaging

Kobayashi, T., Murakami, M., Takeda, Y., Kusumi, A. & Yoshimura, A., 2004 Feb, In : Seikagaku. The Journal of Japanese Biochemical Society. 76, 2, p. 91-100 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Regulation of cytokine and toll-like receptor signaling by SOCS family genes

Takagi, H., Sanada, T., Minoda, Y. & Yoshimura, A., 2004 Dec, In : Nippon rinsho. Japanese journal of clinical medicine. 62, 12, p. 2189-2196 8 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Regulation of TLR signaling and inflammation by SOCS family proteins

Yoshimura, A., Ohishi, H. M. M., Aki, D. & Hanada, T., 2004 Mar 1, In : Journal of Leukocyte Biology. 75, 3, p. 422-427 6 p.

Research output: Contribution to journalReview article

48 Citations (Scopus)
2003

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.

Sasaki, A., Taketomi, T., Kato, R., Saeki, K., Nonami, A., Sasaki, M., Kuriyama, M., Saito, N., Shibuya, M. & Yoshimura, A., 2003 Jan 1, In : Cell cycle (Georgetown, Tex.). 2, 4, p. 280-281 2 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)

Negative regulation of cytokine signaling and inflammatory diseases

Inagaki-Ohara, K., Hanada, T. & Yoshimura, A., 2003 Aug 1, In : Current Opinion in Pharmacology. 3, 4, p. 435-442 8 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)

Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases.

Hanada, T., Kinjyo, I., Inagaki-Ohara, K. & Yoshimura, A., 2003, In : Reviews of physiology, biochemistry and pharmacology. 149, p. 72-86 15 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)

Negative regulation of cytokine signaling influences inflammation

Yoshimura, A., Mori, H., Ohishi, M., Aki, D. & Hanada, T., 2003 Dec, In : Current Opinion in Immunology. 15, 6, p. 704-708 5 p.

Research output: Contribution to journalReview article

96 Citations (Scopus)

Suppressors of cytokine signaling and immunity

Kubo, M., Hanada, T. & Yoshimura, A., 2003 Dec 1, In : Nature Immunology. 4, 12, p. 1169-1176 8 p.

Research output: Contribution to journalReview article

492 Citations (Scopus)
2002

Induction of SOCS family proteins in inflammatory diseases and suppression of inflammatory arthritis model by the adenovirus gene transfer

Yoshimura, A., Shouda, T., Yoshida, T. & Hanada, T., 2002 Dec, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 47, 16 Suppl, p. 2355-2361 7 p.

Research output: Contribution to journalReview article

Regulation of cytokine signaling and inflammation

Hanada, T. & Yoshimura, A., 2002 Aug 1, In : Cytokine and Growth Factor Reviews. 13, 4-5, p. 413-421 9 p.

Research output: Contribution to journalReview article

519 Citations (Scopus)
2000

Negative regulation of cytokine signaling pathways

Yasukawa, H., Sasaki, A. & Yoshimura, A., 2000 Jun 27, In : Annual Review of Immunology. 18, p. 143-164 22 p.

Research output: Contribution to journalReview article

486 Citations (Scopus)

The Jak-Stat pathway in normal and perturbed hematopoiesis

Ward, A. C., Touw, I. & Yoshimura, A., 2000 Jan 1, In : Blood. 95, 1, p. 19-29 11 p.

Research output: Contribution to journalReview article

238 Citations (Scopus)

The janus kinase inhibitor, JAB/SOCS-1, is an interferon-γ inducible gene and determines the sensitivity to interferons

Sakamoto, H., Kinjyo, I. & Yoshimura, A., 2000 May 9, In : Leukemia and Lymphoma. 38, 1-2, p. 49-58 10 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
1998

Physiology and function of the erythropoietin receptor

Yoshimura, A. & Misawa, H., 1998 Jan 1, In : Current Opinion in Hematology. 5, 3, p. 171-176 6 p.

Research output: Contribution to journalReview article

54 Citations (Scopus)

Regulation of JAK-STAT signaling

Yoshimura, A., 1998 Dec 1, In : Biotherapy. 12, 12, p. 1527-1536 10 p.

Research output: Contribution to journalReview article

Signal transduction of cytokine receptors - Structure of receptor and signal transduction mechanism

Yoshimura, A., 1998 Jan 1, In : Biotherapy. 12, 11, p. 1407-1416 10 p.

Research output: Contribution to journalReview article

The CIS/JAB family: Novel negative regulators of JAK signaling pathways

Yoshimura, A., 1998 Jan 1, In : Leukemia. 12, 12, p. 1851-1857 7 p.

Research output: Contribution to journalReview article

Open Access
47 Citations (Scopus)
1997

Signal transduction of the erythropoietin receptor

Yoshimura, A., Masuhara, M., Iwatski, Y. & Matsumoto, T., 1997 Mar, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 38, 3, p. 196-199 4 p.

Research output: Contribution to journalReview article

1994

Activation and signal transduction of the erythropoietin receptor

Yoshimura, A., 1994 Feb, In : Seikagaku. The Journal of Japanese Biochemical Society. 66, 2, p. 154-158 5 p.

Research output: Contribution to journalReview article

1993

Structure, function, and activation of the erythropoietin receptor

Youssoufian, H., Longmore, G., Neumann, D., Yoshimura, A. & Lodish, H. F., 1993 Jan 1, In : Blood. 81, 9, p. 2223-2236 14 p.

Research output: Contribution to journalReview article

Open Access
296 Citations (Scopus)
1987

A molecular basis for multidrug-resistance and reversal of resistance with human malignant cells

Akiyama, S., Kikuchi, H., Yoshimura, A. & Matsumoto, M., 1987 Sep 1, In : Japanese Journal of Cancer and Chemotherapy. 14, 9, p. 2617-2625 9 p.

Research output: Contribution to journalReview article

1984

Infectious cell entry mechanism of enveloped viruses

Ohnishi, S. & Yoshimura, A., 1984 Jun, In : Uirusu. Journal of virology. 34, 1, p. 11-24 14 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)