• 728 Citations
  • 14 h-Index
19962020

Research output per year

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Research Output

2020

Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy

Hayashi, K., Hishikawa, A., Hashiguchi, A., Azegami, T., Yoshimoto, N., Nakamichi, R., Tokuyama, H. & Itoh, H., 2020 Dec 1, In : Scientific reports. 10, 1, 237.

Research output: Contribution to journalArticle

Open Access
2019

Acute Interstitial Nephritis With Karyomegalic Epithelial Cells After Nivolumab Treatment—Two Case Reports

Ryuzaki, M., Tokuyama, H., Uchiyama, K., Nakaya, H., Hasegawa, K., Miyashita, K., Konishi, K., Hashiguchi, A., Wakino, S. & Itoh, H., 2019 Jun 1, In : Clinical Medicine Insights: Case Reports. 12

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

A grading system that predicts the risk of dialysis induction in IgA nephropathy patients based on the combination of the clinical and histological severity

for The Special IgA Nephropathy Study Group, 2019 Jan 22, In : Clinical and experimental nephrology. 23, 1, p. 16-25 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access

Non-invasive liver fibrosis assessment correlates with collagen and elastic fiber quantity in patients with hepatitis C virus infection

Yasui, Y., Abe, T., Kurosaki, M., Matsunaga, K., Higuchi, M., Tamaki, N., Watakabe, K., Okada, M., Wang, W., Shimizu, T., Takaura, K., Masugi, Y., Nakanishi, H., Tsuchiya, K., Takahashi, Y., Itakura, J., Sakurai, U., Hashiguchi, A., Sakamoto, M. & Izumi, N., 2019 Jan, In : Hepatology Research. 49, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
4 Citations (Scopus)
2018

Effectiveness of color correction on the quantitative analysis of histopathological images acquired by different whole-slide scanners

Aziz, M. A., Nakamura, T., Yamaguchi, M., Kiyuna, T., Yamashita, Y., Abe, T., Hashiguchi, A. & Sakamoto, M., 2018 Jan 1, (Accepted/In press) In : Artificial Life and Robotics.

Research output: Contribution to journalArticle

Mesenchymal–epithelial transition of pancreatic cancer cells at perineural invasion sites is induced by Schwann cells

Nishimura, Y., Yamazaki, K., Masugi, Y., Douguchi, J., Kurebayashi, Y., Kubota, N., Ojima, H., Kitago, M., Shinoda, M., Hashiguchi, A. & Sakamoto, M., 2018 Apr 1, In : Pathology International. 68, 4, p. 214-223 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The challenges and promises of quanifying liver fibrosis and steatosis evaluation of liver fibrosis: From the viewpoint of pathology

Hatano, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2018 Jan 1, In : Acta Hepatologica Japonica. 59, 8, p. 415-420 6 p.

Research output: Contribution to journalComment/debate

2017

Extraction of glomeruli in whole slide imaging of kidney biopsy specimens

Ishikawa, M., Watanabe, S., Honda, N., Kobayashi, N., Abe, T., Hashiguchi, A. & Sakamoto, M., 2017, Medical Imaging 2017: Digital Pathology. SPIE, Vol. 10140. 101400U

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Polycythemia, capillary rarefaction, and focal glomerulosclerosis in two adolescents born extremely low birth weight and premature

Asada, N., Tsukahara, T., Furuhata, M., Matsuoka, D., Noda, S., Naganuma, K., Hashiguchi, A. & Awazu, M., 2017 Jul 1, In : Pediatric Nephrology. 32, 7, p. 1275-1278 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Automatic quantification of morphological features for hepatic trabeculae analysis in stained liver specimens

Ishikawa, M., Murakami, Y., Ahi, S. T., Yamaguchi, M., Kobayashi, N., Kiyuna, T., Yamashita, Y., Saito, A., Abe, T., Hashiguchi, A. & Sakamoto, M., 2016 Apr 1, In : Journal of Medical Imaging. 3, 2, 027502.

Research output: Contribution to journalArticle

6 Citations (Scopus)

CD4+ T cell‒dominant insulitis in acute-onset type 1 diabetes mellitus associated with intraductal papillary mucinous adenoma

Yajima, K., Oikawa, Y., Ogata, K., Hashiguchi, A. & Shimada, A., 2016, In : Endocrine journal. 63, 9, p. 841-847 7 p.

Research output: Contribution to journalArticle

Elastin fiber accumulation in liver correlates with the development of hepatocellular carcinoma

Yasui, Y., Abe, T., Kurosaki, M., Higuchi, M., Komiyama, Y., Yoshida, T., Hayashi, T., Kuwabara, K., Takaura, K., Nakakuki, N., Takada, H., Tamaki, N., Suzuki, S., Nakanishi, H., Tsuchiya, K., Itakura, J., Takahashi, Y., Hashiguchi, A., Sakamoto, M. & Izumi, N., 2016 Apr 1, In : PLoS One. 11, 4, e0154558.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Pathological sub-analysis of a multicenter randomized controlled trial of tonsillectomy combined with steroid pulse therapy versus steroid pulse monotherapy in patients with immunoglobulin A nephropathy

Katafuchi, R., Kawamura, T., Joh, K., Hashiguchi, A., Hisano, S., Shimizu, A., Miyazaki, Y., Nagata, M. & Matsuo, S., 2016 Apr 1, In : Clinical and experimental nephrology. 20, 2, p. 244-252 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Renal thrombotic microangiopathy and antiphospholipid syndrome nephropathy in a patient with lupus nephritis

Sakamaki, Y., Konishi, K., Hashiguchi, A., Tomita, S., Kubota, E., Itoh, H. & Hayashi, K., 2016, In : Nihon Jinzo Gakkai shi. 58, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

2015

A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis

Yamaguchi, S., Maruyama, T., Wakino, S., Tokuyama, H., Hashiguchi, A., Tada, S., Homma, K., Monkawa, T., Thomas, J., Miyashita, K., Kurihara, I., Yoshida, T., Konishi, K., Hayashi, K., Hayashi, M. & Itoh, H., 2015 Nov 11, (Accepted/In press) In : BMC Nephrology.

Research output: Contribution to journalArticle

7 Citations (Scopus)

An accurate method of extracting fat droplets in liver images for quantitative evaluation

Ishikawa, M., Kobayashi, N., Komagata, H., Shinoda, K., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2015 Jan 1, Medical Imaging 2015: Digital Pathology. Gurcan, M. N. & Madabhushi, A. (eds.). SPIE, 94200Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9420).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

An efficient wavelet-based roi coding for multiple regions

Shinoda, K., Kobayashi, N., Katoh, A., Komagata, H., Ishikawa, M., Murakami, Y., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2015 Apr 1, In : IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences. E98A, 4, p. 1006-1020 15 p.

Research output: Contribution to journalArticle

Overexpression of CXCR4 on circulating B cells in patients with active systemic lupus erythematosus

Hanaoka, H., Okazaki, Y., Hashiguchi, A., Yasuoka, H., Takeuchi, T. & Kuwana, M., 2015, In : Clinical and Experimental Rheumatology. 33, 6, p. 863-870 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Visualization of acetaminophen-induced liver injury by time-of-flight secondary ion mass spectrometry

Murayama, Y., Satoh, S., Hashiguchi, A., Yamazaki, K., Hashimoto, H. & Sakamoto, M., 2015 Nov 1, In : Analytical Biochemistry. 488, p. 51-58 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

A rare association between Fabry's disease and granulomatosis with polyangiitis: A potential pathogenic link

Hanaoka, H., Hashiguchi, A., Konishi, K., Ishii, T. & Kuwana, M., 2014 Oct 1, In : BMC Nephrology. 15, 1, 157.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Color processing in pathology image analysis system for liver biopsy

Murakami, Y., Abe, T., Yamashita, Y., Yamaguchi, M., Ishikawa, M., Hashiguchi, A., Tomoharu, K., Saito, A. & Sakamoto, M., 2014 Jan 1, In : Final Program and Proceedings - IS and T/SID Color Imaging Conference. 2014-January, January, p. 184-188 5 p.

Research output: Contribution to journalConference article

1 Citation (Scopus)

Computational hepatocellular carcinoma tumor grading based on cell nuclei classification

Atupelage, C., Nagahashi, H., Kimura, F., Yamaguchi, M., Tokiya, A., Hashiguchi, A. & Sakamoto, M., 2014 Oct 1, In : Journal of Medical Imaging. 1, 3, 034501.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Distinct cell clusters touching islet cells induce islet cell replication in association with over-expression of Regenerating Gene (REG) protein in fulminant type 1 diabetes

Aida, K., Saitoh, S., Nishida, Y., Yokota, S., Ohno, S., Mao, X., Akiyama, D., Tanaka, S., Awata, T., Shimada, A., Oikawa, Y., Shimura, H., Furuya, F., Takizawa, S., Ichijo, M., Ichijo, S., Itakura, J., Fujii, H., Hashiguchi, A., Takasawa, S. & 2 others, Endo, T. & Kobayashi, T., 2014 Apr 23, In : PloS one. 9, 4, e95110.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Label-free visualization of acetaminophen-induced liver injury by high-speed stimulated Raman scattering spectral microscopy and multivariate image analysis

Satoh, S., Otsuka, Y., Ozeki, Y., Itoh, K., Hashiguchi, A., Yamazaki, K., Hashimoto, H. & Sakamoto, M., 2014 Oct 1, In : Pathology international. 64, 10, p. 518-526 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Overestimation of the risk of progression to end-stage renal disease in the poor prognosis' group according to the 2002 Japanese histological classification for immunoglobulin a nephropathy

Miyazaki, Y., Kawamura, T., Joh, K., Okonogi, H., Koike, K., Utsunomiya, Y., Ogura, M., Matsushima, M., Yoshimura, M., Horikoshi, S., Suzuki, Y., Furusu, A., Yasuda, T., Shirai, S., Shibata, T., Endoh, M., Hattori, M., Akioka, Y., Katafuti, R., Hashiguchi, A. & 3 others, Kimura, K., Matsuo, S. & Tomino, Y., 2014 Jan 1, In : Clinical and experimental nephrology. 18, 3, p. 475-480 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Supratentorial neurenteric cyst with spontaneous repetitive intracystic hemorrhage mimicking brain abscess: A case report

Kitamura, Y., Sasaki, H., Hashiguchi, A., Momoshima, S., Shidoh, S. & Yoshida, K., 2014 Jan 1, In : Neurosurgical Review. 37, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2013

A histologic classification of IgA nephropathy for predicting long-term prognosis: Emphasis on end-stage renal disease

Kawamura, T., Joh, K., Okonogi, H., Koike, K., Utsunomiya, Y., Miyazaki, Y., Matsushima, M., Yoshimura, M., Horikoshi, S., Suzuki, Y., Furusu, A., Yasuda, T., Shirai, S., Shibata, T., Endoh, M., Hattori, M., Akioka, Y., Katafuchi, R., Hashiguchi, A., Kimura, K. & 2 others, Matsuo, S. & Tomino, Y., 2013 May 14, In : Journal of Nephrology. 26, 2, p. 350-357 8 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

An algorithm to evaluate the number of trabecular cell layers using nucleus arrangement applied to hepatocellular carcinoma

Komagata, H., Kobayashi, N., Katoh, A., Ohnuki, Y., Ishikawa, M., Shinoda, K., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2013 Jun 10, Medical Imaging 2013: Digital Pathology. 86760M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8676).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

A role of image processing technology for pathological image - A research project for quantitative pathology

Kobayashi, N., Sakamoto, M., Hashiguchi, A., Yamaguchi, M., Nagahashi, H. & Saito, A., 2013, In : Journal of the Institute of Image Electronics Engineers of Japan. 42, 2, p. 267-272 6 p.

Research output: Contribution to journalArticle

Automatic classification of hepatocellular carcinoma images based on nuclear and structural features

Kiyuna, T., Saito, A., Marugame, A., Yamashita, Y., Ogura, M., Cosatto, E., Abe, T., Hashiguchi, A. & Sakamoto, M., 2013, Medical Imaging 2013: Digital Pathology. 86760Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8676).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Automatic segmentation of hepatocellular structure from HE-stained liver tissue

Ishikawa, M., Ahi, S. T., Murakami, Y., Kimura, F., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2013 Jun 10, Medical Imaging 2013: Digital Pathology. 867611. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8676).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Computational cell classification methodology for hepatocellular carcinoma

Atupelage, C., Nagahashi, H., Kimura, F., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2013 Jan 1, p. 21-27. 7 p.

Research output: Contribution to conferencePaper

Computational grading of hepatocellular carcinoma using multifractal feature description

Atupelage, C., Nagahashi, H., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2013 Jan 1, In : Computerized Medical Imaging and Graphics. 37, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Leukemia kidney infiltration can cause secondary polycythemia by activating hypoxia-inducible factor (HIF) pathway

Osumi, T., Awazu, M., Fujimura, E., Yamazaki, F., Hashiguchi, A. & Shimada, H., 2013 Jun 1, In : European Journal of Pediatrics. 172, 6, p. 829-832 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Multifractal computation for nuclear classification and hepatocellular carcinoma grading

Atupelage, C., Nagahashi, H., Yamaguchi, M., Kimura, F., Abe, T., Hashiguchi, A. & Sakamoto, M., 2013 Sep 18, Proceedings of the IASTED International Conference on Biomedical Engineering, BioMed 2013. p. 415-420 6 p. (Proceedings of the IASTED International Conference on Biomedical Engineering, BioMed 2013).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Proposal of remission criteria for IgA nephropathy

Matsuo, S., Kawamura, T., Suzuki, Y., Joh, K., Tomino, Y., Horikoshi, S., Nishino, T., Yoshikawa, N., Hattori, M., Kimura, K., Yasuda, T., Shirai, S., Shibata, T., Yoshimura, M., Utsunomiya, Y., Endoh, M., Sakamoto, N., Matsushima, M., Miyazaki, Y., Yasuda, Y. & 11 others, Yokoo, T., Kagami, S., Hataya, H., Suzuki, H., Matsuzaki, K., Uchida, S., Ito, T., Shimizu, A., Katafuchi, R., Hisano, S. & Hashiguchi, A., 2013, In : Japanese Journal of Nephrology. 55, 7, p. 1249-1254 6 p.

Research output: Contribution to journalArticle

Quantification of collagen and elastic fibers using whole-slide images of liver biopsy specimens

Abe, T., Hashiguchi, A., Yamazaki, K., Ebinuma, H., Saito, H., Kumada, H., Izumi, N., Masaki, N. & Sakamoto, M., 2013 Jun, In : Pathology international. 63, 6, p. 305-310 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Renal thrombotic microangiopathy in a patient with septic disseminated intravascular coagulation

Sakamaki, Y., Konishi, K., Hayashi, K., Hashiguchi, A., Hayashi, M., Kubota, E., Saruta, T. & Itoh, H., 2013 Nov 27, In : BMC Nephrology. 14, 1, 260.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells

Uekita, T., Fujii, S., Miyazawa, Y., Hashiguchi, A., Abe, H., Sakamoto, M. & Sakai, R., 2013 Jul, In : Cancer science. 104, 7, p. 865-870 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

What is the most effective tool for detecting prostate cancer using a standard MR scanner?

Osugi, K., Tanimoto, A., Nakashima, J., Shinoda, K., Hashiguchi, A., Oya, M., Jinzaki, M. & Kuribayashi, S., 2013 Dec 1, In : Magnetic Resonance in Medical Sciences. 12, 4, p. 271-280 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2012

Classification of prostate histopathology images based on multifractal analysis

Atupelage, C., Nagahashi, H., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2012 Dec, In : IEICE Transactions on Information and Systems. E95-D, 12, p. 3037-3045 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Insulinoma may mask the existence of Type1 diabetes

Oikawa, Y., Katsuki, T., Kawasaki, M., Hashiguchi, A., Mukai, K., Handa, K., Tomita, M., Kabeya, Y., Asai, Y., Iwase, K., Hirose, S., Koyama, K., Atsumi, Y. & Shimada, A., 2012 Jul 1, In : Diabetic Medicine. 29, 7, p. e138-e141

Research output: Contribution to journalArticle

4 Citations (Scopus)

MPO-ANCA associated crescentic glomerulonephritis with numerous immune complexes: Case report

Morizane, R., Konishi, K., Hashiguchi, A., Tokuyama, H., Wakino, S., Kawabe, H., Hayashi, M., Hayashi, K. & Itoh, H., 2012 Jun 4, In : BMC Nephrology. 13, 1, 32.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Multifractal feature descriptor for diagnosing liver and prostate cancers in H&E stained histologic images

Atupelage, C., Nagahashi, H., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2012 Aug 15, 2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Proceedings. p. 298-301 4 p. 6235543. (Proceedings - International Symposium on Biomedical Imaging).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multifractal feature descriptor for grading Hepatocellular carcinoma

Atupelage, C., Nagahashi, H., Yamaguchi, M., Abe, T., Hashiguchi, A. & Sakamoto, M., 2012 Dec 1, ICPR 2012 - 21st International Conference on Pattern Recognition. p. 129-132 4 p. 6460089. (Proceedings - International Conference on Pattern Recognition).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Multifractal feature descriptor for histopathology

Atupelage, C., Nagahashi, H., Yamaguchi, M., Sakamoto, M. & Hashiguchi, A., 2012 Feb 13, In : Analytical Cellular Pathology. 35, 2, p. 123-126 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Second-line chemotherapy for refractory small cell neuroendocrine carcinoma of the esophagus that relapsed after complete remission with irinotecan plus cisplatin therapy: Case report and review of the literature

Funakoshi, S., Hashiguchi, A., Teramoto, K., Miyata, N., Kurita, S., Adachi, M., Hamamoto, Y., Higuchi, H., Takaishi, H. & Hibi, T., 2012 Nov 19, In : Oncology Letters. 5, 1, p. 117-122 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2011

A case of membranous nephropathy with primary biliary cirrhosis and cyclosporine-induced remission

Sakamaki, Y., Hayashi, M., Wakino, S., Fukuda, S., Konishi, K., Hashiguchi, A., Hayashi, K. & Itoh, H., 2011 Feb 11, In : Internal Medicine. 50, 3, p. 233-238 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)