• 18950 Citations
  • 73 h-Index
1982 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Review article
2018

Modeling phenotypes of malignant gliomas

Sampetrean, O. & Saya, H., 2018 Jan 1, In : Cancer Science. 109, 1, p. 6-14 9 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Prospects for new lung cancer treatments that target EMT signaling

Otsuki, Y., Saya, H. & Arima, Y., 2018 Mar 1, In : Developmental Dynamics. 247, 3, p. 462-472 11 p.

Research output: Contribution to journalReview article

28 Citations (Scopus)
2013

Redox regulation in stem-like cancer cells by CD44 variant isoforms

Nagano, O., Okazaki, S. & Saya, H., 2013 Oct 31, In : Oncogene. 32, 44, p. 5191-5198 8 p.

Research output: Contribution to journalReview article

156 Citations (Scopus)
2012

Pyruvate kinase M2: Multiple faces for conferring benefits on cancer cells

Tamada, M., Suematsu, M. & Saya, H., 2012 Oct 15, In : Clinical Cancer Research. 18, 20, p. 5554-5561 8 p.

Research output: Contribution to journalReview article

136 Citations (Scopus)
2011

[Encounter of cancer cells with bone. The significance of cancer stem cells and epithelial-mesenchymal transition in tumor invasion and metastasis].

Yoshida, G. J. & Saya, H., 2011 Mar 1, In : Clinical calcium. 21, 3, p. 411-417 7 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2010

Breast cancer stem cells

Kai, K., Arima, Y., Kamiya, T. & Saya, H., 2010 Apr 1, In : Breast Cancer. 17, 2, p. 80-85 6 p.

Research output: Contribution to journalReview article

65 Citations (Scopus)

Cancer stem cells in malignant glioma - The mechanism of cancer initiation and the therapeutic development

Nakano, I. & Saya, H., 2010 Oct 1, In : Neurological Surgery. 38, 10, p. 879-889 11 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)
2009

[Mitotic regulation and carcinogenesis].

Saya, H., Zhang, D. & Oltea, S., 2009 Mar 1, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54, 4 Suppl, p. 561-567 7 p.

Research output: Contribution to journalReview article

Current clinical trials using new targeted therapies for myeloid leukemia and the research trends

Ishizawa, J. & Saya, H., 2009 Oct, In : Nippon rinsho. Japanese journal of clinical medicine. 67, 10, p. 1932-1937 6 p.

Research output: Contribution to journalReview article

Molecularly targeted therapies for glioma

Yamanaka, R. & Saya, H., 2009 Dec 1, In : Annals of Neurology. 66, 6, p. 717-729 13 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Molecular mechanism of cell death induced by chemotherapeutic agents

Saya, H., 2009 Jul 1, In : Brain and Nerve. 61, 7, p. 843-847 5 p.

Research output: Contribution to journalReview article

Molecular mechanism regulating effect of anti-cancer agents

Saya, H., 2009 Jan, In : Japanese Journal of Cancer and Chemotherapy. 36, 1, p. 1-5 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2008

Role of CD44-mediated signal in cancer invasion and metastasis

Saya, H. & Nagano, O., 2008 Aug 1, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 53, 10, p. 1225-1230 6 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
2007

Aurora kinases: Functions and roles in tumorigenesis

Saya, H., 2007 Dec 1, In : Seikagaku. 79, 2, p. 131-139 9 p.

Research output: Contribution to journalReview article

The UHRF family: Oncogenes that are drugable targets for cancer therapy in the near future?

Bronner, C., Achour, M., Arima, Y., Chataigneau, T., Saya, H. & Schini-Kerth, V. B., 2007 Sep 1, In : Pharmacology and Therapeutics. 115, 3, p. 419-434 16 p.

Research output: Contribution to journalReview article

117 Citations (Scopus)
2006

Dynamics of mitotic spindle

Kinoshita, K. & Saya, H., 2006 May 1, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.. 51, 6 Suppl, p. 761-766 6 p.

Research output: Contribution to journalReview article

Molecular mechanisms of anti-cancer therapies

Saya, H., 2006 Oct, In : Japanese Journal of Neurosurgery. 15, 10, p. 688-693 6 p.

Research output: Contribution to journalReview article

Open Access
2005

Aurora-A - A guardian of poles

Marumoto, T., Zhang, D. & Saya, H., 2005 Jan 1, In : Nature Reviews Cancer. 5, 1, p. 42-50 9 p.

Research output: Contribution to journalReview article

553 Citations (Scopus)

Molecular mechanisms of brain tumor invasion

Saya, H., 2005 Sep, In : Nippon rinsho. Japanese journal of clinical medicine. 63 Suppl 9, p. 61-67 7 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2004

Mechanism and biological significance of CD44 cleavage

Nagano, O. & Saya, H., 2004 Dec 1, In : Cancer science. 95, 12, p. 930-935 6 p.

Research output: Contribution to journalReview article

276 Citations (Scopus)
2003

Correlation of molecular genetic analysis of p53, MDM2, p16, PTEN, and EGFR and survival of patients with anaplastic astrocytoma and glioblastoma

Ushio, Y., Tada, K., Shiraishi, S., Kamiryo, T., Shinojima, N., Kochi, M. & Saya, H., 2003 Dec 1, In : Frontiers in Bioscience. 8, p. e282-e289

Research output: Contribution to journalReview article

11 Citations (Scopus)

Correlation of molecular genetic analysis of p53, MDM2, p16, PTEN, and EGFR and survival of patients with anaplastic astrocytoma and glioblastoma.

Ushio, Y., Tada, K., Shiraishi, S., Kamiryo, T., Shinojima, N., Kochi, M. & Saya, H., 2003 May 1, In : Frontiers in bioscience : a journal and virtual library. 8, p. e281-288

Research output: Contribution to journalReview article

17 Citations (Scopus)
2000

Calpain-dependent proteolysis of NF2 protein: Involvement in schwannomas and meningiomas

Kimura, Y., Saya, H. & Nakao, M., 2000 Dec 1, In : Neuropathology. 20, 3, p. 153-160 8 p.

Research output: Contribution to journalReview article

28 Citations (Scopus)
1999

Emerging therapeutic targets in schwannomas and meningiomas: The neurofibromatosis Type 2 protein

Nakao, M., Kimura, Y. & Saya, H., 1999 Jun 1, In : Expert Opinion on Therapeutic Targets. 3, 2, p. 335-364 30 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
1998

Neurosurgery and molecular biology: (Series 1) Basic knowledge for understanding molecular biology of the cell

Nakamura, H. & Saya, H., 1998 Mar 1, In : Neurological Surgery. 26, 3, p. 200-206 7 p.

Research output: Contribution to journalReview article

1995

Implication of cell cycle regulating genes in carcinogenesis

Hanada, N. & Saya, H., 1995 Aug, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 40, 11, p. 1713-1720 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
1994

The CD44 adhesion molecule and metastasis

Tanabe, K. K. & Saya, H., 1994, In : Critical Reviews in Oncogenesis. 5, 2-3, p. 201-212 12 p.

Research output: Contribution to journalReview article

48 Citations (Scopus)
1993

Epidemiology, cytogenetics, and molecular biology of brain tumors

Kyritsis, A. P. & Saya, H., 1993 Jan 1, In : Current Opinion in Oncology. 5, 3, p. 474-480 7 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)

Molecular, genetic, and biologic aspects of primary brain tumors

Steck, P. A., Bruner, J. M., Pershouse, M. A., Hadi, A., Conrad, C. A., Yung, W. K. A. & Saya, H., 1993 Jan 1, In : Cancer Bulletin. 45, 4, p. 296-303 8 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Molecular pathogenesis and management of gliomas

Kyritsis, A. P., Saya, H. & Levin, V. A., 1993 Jan 1, In : Neuroimaging Clinics of North America. 3, 4, p. 735-744 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
1991

Pathways of oncogenesis in primary brain tumors

Steck, P. A. & Saya, H., 1991 Jan 1, In : Current Opinion in Oncology. 3, 3, p. 476-484 9 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)