• 382 Citations
  • 10 h-Index
1992 …2019
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Research Output 1992 2019

  • 382 Citations
  • 10 h-Index
  • 42 Article
  • 2 Comment/debate
  • 1 Review article
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Article
2019

Development of an electronic medical record-based algorithm to identify patients with Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan

Fukasawa, T., Takahashi, H., Kameyama, N., Fukuda, R., Furuhata, S., Tanemura, N., Amagai, M. & Urushihara, H., 2019 Jan 1, In : PloS one. 14, 8, e0221130.

Research output: Contribution to journalArticle

Open Access
Electronic medical equipment
Stevens-Johnson Syndrome
Electronic Health Records
Poisons
electronics
Open Access
Human Influenza
Japan
Vaccination
Datasets
Occupational Health

Medications and fall risk: a case–control study in nursing home residents in Japan

Park, H., Satoh, H., Miki, A., Maki, H., Asai, K., Shiraishi, A., Urushihara, H. & Sawada, Y., 2019 Jan 1, In : Aging Clinical and Experimental Research.

Research output: Contribution to journalArticle

Nursing Homes
Japan
Accidental Falls
Facility Regulation and Control
Memantine

日米における適応的デザインを用いた臨床試験の現状

Translated title of the contribution: Application of adaptive designs in clinical trials in Japan and the United StatesYamakawa, N., Teramukai, S., Hatta, T. & Urushihara, H., 2019 Jan 1, In : Japanese Journal of Clinical Pharmacology and Therapeutics. 50, 4, p. 149-156 8 p.

Research output: Contribution to journalArticle

Japan
Clinical Trials
Databases
Pharmaceutical Preparations
2018
4 Citations (Scopus)

Comparative effectiveness and safety of warfarin and dabigatran in patients with non-valvular atrial fibrillation in Japan: A claims database analysis

Koretsune, Y., Yamashita, T., Yasaka, M., Ono, Y., Hirakawa, T., Ishida, K., Kuroki, D., Sumida, T. & Urushihara, H., 2018 Jan 1, (Accepted/In press) In : Journal of Cardiology.

Research output: Contribution to journalArticle

Insurance Claim Review
Warfarin
Atrial Fibrillation
Japan
Databases
4 Citations (Scopus)

Effectiveness of influenza vaccination for children in Japan: Four-year observational study using a large-scale claims database

Shibata, N., Kimura, S., Hoshino, T., Takeuchi, M. & Urushihara, H., 2018 Jan 1, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

observational studies
influenza
Human Influenza
Observational Studies
Japan
1 Citation (Scopus)
Functional Food
randomized clinical trials
Japan
learning
Randomized Controlled Trials

Nationwide survey on informed consent and ethical review at hospitals conducting post-marketing studies sponsored by pharmaceutical companies

Urushihara, H., Murakami, Y., Matsui, K. & Tashiroc, S., 2018 Jan 1, In : Yakugaku Zasshi. 138, 1, p. 63-71 9 p.

Research output: Contribution to journalArticle

Ethical Review
Marketing
Informed Consent
Pharmaceutical Preparations
Pharmacists
Off-Label Use
Psychotropic Drugs
Prescriptions
Japan
Databases
3 Citations (Scopus)

Persistence of oral antidiabetic treatment for type 2 diabetes characterized by drug class, patient characteristics and severity of renal impairment: A Japanese database analysis

Kadowaki, T., Sarai, N., Hirakawa, T., Taki, K., Iwasaki, K. & Urushihara, H., 2018 Jan 1, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Biguanides
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Databases
2017
Tokyo
Cholinergic Antagonists
Health Surveys
Hypnotics and Sedatives
Pharmaceutical Preparations
2015
15 Citations (Scopus)

Cost-effectiveness analysis of EGFR mutation testing and gefitinib as first-line therapy for non-small cell lung cancer

Narita, Y., Matsushima, Y., Shiroiwa, T., Chiba, K., Nakanishi, Y., Kurokawa, T. & Urushihara, H., 2015 Oct 1, In : Lung Cancer. 90, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Cost-Benefit Analysis
Quality-Adjusted Life Years
Mutation
5 Citations (Scopus)

Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: A multicenter, randomized controlled trial

Kita, F., Hinotsu, S., Yorifuji, T., Urushihara, H., Shimakawa, T., Kishida, K., Wakazono, Y., Yamauchi, E., Sasaki, H., Nakahata, T. & Kawakami, K., 2015 Mar 4, In : Asia-Pacific Journal of Public Health. 27, 2, p. NP174-NP183

Research output: Contribution to journalArticle

Domperidone
Fluid Therapy
Gastroenteritis
Japan
Randomized Controlled Trials
56 Citations (Scopus)

Medications associated with falls in older people: Systematic review of publications from a recent 5-year period

Park, H., Satoh, H., Miki, A., Urushihara, H. & Sawada, Y., 2015 Dec 1, In : European Journal of Clinical Pharmacology. 71, 12, p. 1429-1440 12 p.

Research output: Contribution to journalArticle

Publications
Polypharmacy
Hypnotics and Sedatives
Antihypertensive Agents
Antidepressive Agents
3 Citations (Scopus)
Pharmaceutical Preparations
Clinical Trials
Japan
Health
Tolnaftate
16 Citations (Scopus)

Prescription patterns and trends in anti-rheumatic drug use based on a large-scale claims database in Japan

Katada, H., Yukawa, N., Urushihara, H., Tanaka, S., Mimori, T. & Kawakami, K., 2015 May 1, In : Clinical Rheumatology. 34, 5, p. 949-956 8 p.

Research output: Contribution to journalArticle

Antirheumatic Agents
Prescriptions
Rheumatoid Arthritis
Japan
Databases
5 Citations (Scopus)

Price difference as a predictor of the selection between brand name and generic statins in Japan

Takizawa, O., Urushihara, H., Tanaka, S. & Kawakami, K., 2015, In : Health Policy. 119, 5, p. 612-619 8 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Names
Japan
Generic Drugs
Pharmacies
2014
Investigational Drugs
Drug and Narcotic Control
Japan
Clinical Trials
Research Personnel
10 Citations (Scopus)

Application of a self-controlled case series study to a database study in children

Ueyama, H., Hinotsu, S., Tanaka, S., Urushihara, H., Nakamura, M., Nakamura, Y. & Kawakami, K., 2014, In : Drug Safety. 37, 4, p. 259-268 10 p.

Research output: Contribution to journalArticle

Databases
Confidence Intervals
Bronchitis
Eczema
Inpatients

Correction: Prescribing pattern of anti-parkinson drugs in Japan: a trend analysis from 2005 to 2010 (PLoS ONE (2014) 9, 6 (e99021) DOI: 10.1371/journal.pone.0099021)

Nakaoka, S., Ishizaki, T., Urushihara, H., Satoh, T. & Ikeda, S., 2014 Aug 19, In : PLoS One. 9, 8, e106217.

Research output: Contribution to journalArticle

Pharmaceutical Preparations

In reply.

Urushihara, H., 2014 Jan, In : Menopause. 21, 1, p. 110 1 p.

Research output: Contribution to journalArticle

Bone Density Conservation Agents
Postmenopause
Postmenopausal Osteoporosis
Stroke
Raloxifene Hydrochloride

Letters to the Editor

Urushihara, H., 2014, In : Menopause. 21, 1, p. 110 1 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pharmaceutical company perspectives on current safety risk communications in Japan

Urushihara, H., Kobashi, G., Masuda, H., Taneichi, S., Yamamoto, M., Nakayama, T., Kawakami, K., Matsuda, T., Ohta, K. & Sugimori, H., 2014, In : SpringerPlus. 3, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Japan
Communication
Safety
Pharmaceutical Preparations
Pharmacovigilance
12 Citations (Scopus)

Prescribing pattern of anti-parkinson drugs in Japan: A trend analysis from 2005 to 2010

Nakaoka, S., Ishizaki, T., Urushihara, H., Satoh, T., Ikeda, S., Yamamoto, M. & Nakayama, T., 2014 Jun 6, In : PLoS One. 9, 6, e99021.

Research output: Contribution to journalArticle

Japan
drugs
Parkinson disease
Dopamine Agonists
Pergolide
2 Citations (Scopus)

Responsiveness of the Japanese Osteoporosis Quality of Life questionnaire in women with postmenopausal osteoporosis

Urushihara, H., Yoh, K., Hamaya, E., Taketsuna, M. & Tanaka, K., 2014 Dec 12, In : Health and Quality of Life Outcomes. 12, 1, 178.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Osteoporosis
Quality of Life
Pain Measurement
Activities of Daily Living

Transaction cost analysis of the new drug application process: A case study of a multinational pharmaceutical company in Japan

Hamada, S., Shibata, A., Urushihara, H., Sengoku, S., Suematsu, C. & Kawakami, K., 2014, In : Therapeutic Innovation and Regulatory Science. 48, 3, p. 371-377 7 p.

Research output: Contribution to journalArticle

Japan
Costs and Cost Analysis
Pharmaceutical Preparations
Equipment and Supplies
Salaries and Fringe Benefits
2013
3 Citations (Scopus)

Biased Safety Reporting in Blinded Randomized Clinical Trials: Meta-Analysis of Angiotensin Receptor Blocker Trials

Takabayashi, N., Urushihara, H. & Kawakami, K., 2013 Sep 23, In : PLoS One. 8, 9, e75027.

Research output: Contribution to journalArticle

angiotensins
randomized clinical trials
Angiotensin Receptor Antagonists
meta-analysis
Meta-Analysis
3 Citations (Scopus)

Economic evaluation of pravastatin for primary prevention of coronary artery disease based on risk prediction from JALS-ECC in Japan

Onishi, Y., Hinotsu, S., Nakao, Y. M., Urushihara, H. & Kawakami, K., 2013 May, In : Value in Health Regional Issues. 2, 1, p. 5-12 8 p.

Research output: Contribution to journalArticle

Pravastatin
Primary Prevention
Cost-Benefit Analysis
Coronary Artery Disease
Japan
2012
45 Citations (Scopus)

Chromosomal variability of human mesenchymal stem cells cultured under hypoxic conditions

Ueyama, H., Horibe, T., Hinotsu, S., Tanaka, T., Inoue, T., Urushihara, H., Kitagawa, A. & Kawakami, K., 2012 Jan, In : Journal of Cellular and Molecular Medicine. 16, 1, p. 72-82 11 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Chromosome Aberrations
Chromosomal Instability
Cell Proliferation
Bone Marrow
4 Citations (Scopus)
Pharmaceutical Databases
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Antihypertensive Agents
Retrospective Studies
Blood Pressure
2 Citations (Scopus)

Emergency authorization of medical products: Regulatory challenges from the 2009 H1N1 influenza pandemic in Japan

Urushihara, H., Matsui, S. & Kawakami, K., 2012 Dec 1, In : Biosecurity and Bioterrorism. 10, 4, p. 372-382 11 p.

Research output: Contribution to journalArticle

influenza
authorization
Pandemics
Human Influenza
contagious disease
40 Citations (Scopus)

Increased Risk of Acute Pancreatitis in Patients with Type 2 Diabetes: An Observational Study Using a Japanese Hospital Database

Urushihara, H., Taketsuna, M., Liu, Y., Oda, E., Nakamura, M., Nishiuma, S. & Maeda, R., 2012 Dec 27, In : PLoS One. 7, 12, e53224.

Research output: Contribution to journalArticle

pancreatitis
observational studies
Medical problems
noninsulin-dependent diabetes mellitus
Pancreatitis
5 Citations (Scopus)

Quality of life in raloxifene-treated Japanese women with postmenopausal osteoporosis: A prospective, postmarketing observational study

Yoh, K., Hamaya, E., Urushihara, H., Iikuni, N., Yamamoto, T., Taketsuna, M., Miyauchi, A., Sowa, H. & Tanaka, K., 2012 Nov, In : Current Medical Research and Opinion. 28, 11, p. 1757-1766 10 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Observational Studies
Quality of Life
Pain
Osteoporosis
2011
11 Citations (Scopus)

Echocardiography for the detection of valvulopathy associated with the use of ergot-derived dopamine agonists in patients with Parkinson's disease

Nakaoka, S., Ishizaki, T., Urushihara, H., Satoh, T., Ikeda, S., Morikawa, K. & Nakayama, T., 2011, In : Internal Medicine. 50, 7, p. 687-694 8 p.

Research output: Contribution to journalArticle

Dopamine Agonists
Parkinson Disease
Echocardiography
Pergolide
Pharmaceutical Preparations
4 Citations (Scopus)

Night-to-night variability of sleep latency significantly predicts the magnitude of subsequent change in sleep latency during placebo administration

Ogawa, A., Hinotsu, S., Urushihara, H. & Kawakami, K., 2011 Jun, In : Sleep Medicine. 12, 6, p. 565-571 7 p.

Research output: Contribution to journalArticle

Sleep
Placebos
Sleep Initiation and Maintenance Disorders
Double-Blind Method
Outpatients
19 Citations (Scopus)

Oseltamivir prescription and regulatory actions vis-à-vis abnormal behavior risk in Japan: Drug utilization study using a nationwide pharmacy database

Urushihara, H., Doi, Y., Arai, M., Matsunaga, T., Fujii, Y., Iino, N., Kawamura, T. & Kawakami, K., 2011 Dec 6, In : PLoS One. 6, 12, e28483.

Research output: Contribution to journalArticle

Drug Utilization
Oseltamivir
abnormal behavior
national surveys
Risk-Taking
3 Citations (Scopus)

The current status of umbilical cord blood collection in Japanese medical centers: Survey of obstetricians

Tada, N., Hinotsu, S., Urushihara, H., Kita, F., Kai, S., Takahashi, T. A., Kato, S., Takanashi, M., Ito, K., Sawai, H., Maekawa, T., Kosugi, S. & Kawakami, K., 2011 Jun, In : Transfusion and Apheresis Science. 44, 3, p. 263-268 6 p.

Research output: Contribution to journalArticle

Fetal Blood
Interviews
Physicians
Surveys and Questionnaires
2010
3 Citations (Scopus)

Development safety update reports and proposals for effective and efficient risk communication

Urushihara, H. & Kawakami, K., 2010, In : Drug Safety. 33, 5, p. 341-352 12 p.

Research output: Contribution to journalArticle

Safety
Communication
Investigational Drugs
Life Cycle Stages
Life cycle
2009
8 Citations (Scopus)

Raloxifene and stroke risks in Japanese postmenopausal women with osteoporosis on postmarketing surveillance

Urushihara, H., Kikuchi, N., Yamada, M., Yoshiki, F. & Miyauchi, A., 2009 Sep, In : Menopause. 16, 5, p. 971-977 7 p.

Research output: Contribution to journalArticle

Osteoporosis
Stroke
Raloxifene Hydrochloride
Japan
Population
1995
22 Citations (Scopus)

Inhibitory effects of antidepressants on NMDA-induced currents in Xenopus oocytes injected with rat brain RNA

Tohda, M., Urushihara, H. & Nomura, Y., 1995, In : Neurochemistry International. 26, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

Desipramine
N-Methylaspartate
Xenopus
Antidepressive Agents
Oocytes
1992
64 Citations (Scopus)

Selective potentiation of N-methyl-D-aspartate-induced current by protein kinase C in Xenopus oocytes injected with rat brain RNA

Urushihara, H., Tobda, M. & Nomura, Y., 1992 Jun 15, In : Journal of Biological Chemistry. 267, 17, p. 11697-11700 4 p.

Research output: Contribution to journalArticle

Induced currents
N-Methylaspartate
Xenopus
Protein Kinase C
Oocytes

Tryptophan inhibits the [3H]Glutamate uptake into Xenopus oocytes injected with rat brain mRNA

Tohda, M., Urushihara, H. & Nomura, Y., 1992, In : Japanese Journal of Pharmacology. 59, 4, p. 477-479 3 p.

Research output: Contribution to journalArticle

Xenopus
Tryptophan
Oocytes
Glutamic Acid
Messenger RNA