• 675 Citations
  • 12 h-Index
20082020

Research output per year

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Research Output

  • 675 Citations
  • 12 h-Index
  • 20 Article
  • 2 Review article
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Article
2020

Circulating FGF23 is not associated with cardiac dysfunction, atherosclerosis, infection or inflammation in hemodialysis patients

Takashi, Y., Wakino, S., Minakuchi, H., Ishizu, M., Kuroda, A., Shima, H., Tashiro, M., Miya, K., Okada, K., Minakuchi, J., Kawashima, S., Matsuhisa, M., Matsumoto, T. & Fukumoto, S., 2020 Jan 1, In : Journal of Bone and Mineral Metabolism. 38, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy

Muraoka, H., Hasegawa, K., Sakamaki, Y., Minakuchi, H., Kawaguchi, T., Yasuda, I., Kanda, T., Tokuyama, H., Wakino, S. & Itoh, H., 2019 Apr 2, In : Cell Reports. 27, 1, p. 199-212.e5

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2018
15 Citations (Scopus)

Peritoneal dialysis patient having fish bone-induced colon perforation

Endo, S., Minakuchi, H. & Yoshida, T., 2018 Jan 1, (Accepted/In press) In : Clinical and Experimental Nephrology.

Research output: Contribution to journalArticle

2017

Aldosterone and Insulin Resistance: Vicious Combination in Patients on Maintenance Hemodialysis

Wakino, S., Minakuchi, H., Miya, K., Takamatsu, N., Tada, H., Tani, E., Inamoto, H., Minakuchi, J., Kawashima, S. & Itoh, H., 2017 Jan 1, (Accepted/In press) In : Therapeutic Apheresis and Dialysis.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules

Futatsugi, K., Tokuyama, H., Shibata, S., Naitoh, M., Kanda, T., Minakuchi, H., Yamaguchi, S., Hayashi, K., Minamishima, Y. A., Yanagita, M., Wakino, S. & Itoh, H., 2016 Nov 9, In : Scientific Reports. 6, 36533.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The role of adipose tissue asymmetric dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in adipose tissue phenotype and metabolic abnormalities in subtotally nephrectomized rats

Minakuchi, H., Wakino, S., Hosoya, K., Sueyasu, K., Hasegawa, K., Shinozuka, K., Yoshifuji, A., Futatsugi, K., Komatsu, M., Kanda, T., Tokuyama, H., Hayashi, K. & Itoh, H., 2016 Mar 1, In : Nephrology Dialysis Transplantation. 31, 3, p. 413-423 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015

Insulin resistance in chronic kidney disease is ameliorated by spironolactone in rats and humans

Hosoya, K., Minakuchi, H., Wakino, S., Fujimura, K., Hasegawa, K., Komatsu, M., Yoshifuji, A., Futatsugi, K., Shinozuka, K., Washida, N., Kanda, T., Tokuyama, H., Hayashi, K. & Itoh, H., 2015 Apr 8, In : Kidney international. 87, 4, p. 749-760 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2014

Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice

Fujimura, K., Wakino, S., Minakuchi, H., Hasegawa, K., Hosoya, K., Komatsu, M., Kaneko, Y., Shinozuka, K., Washida, N., Kanda, T., Tokuyama, H., Hayashi, K. & Itoh, H., 2014 Apr 18, In : PloS one. 9, 4, e94373.

Research output: Contribution to journalArticle

23 Citations (Scopus)
4 Citations (Scopus)
2013

Renal tubular sirt1 attenuates diabetic albuminuria by epigenetically suppressing claudin-1 overexpression in podocytes

Hasegawa, K., Wakino, S., Simic, P., Sakamaki, Y., Minakuchi, H., Fujimura, K., Hosoya, K., Komatsu, M., Kaneko, Y., Kanda, T., Kubota, E., Tokuyama, H., Hayashi, K., Guarente, L. & Itoh, H., 2013 Nov 1, In : Nature medicine. 19, 11, p. 1496-1504 9 p.

Research output: Contribution to journalArticle

176 Citations (Scopus)

The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1-dependent mechanism in mice

Hasegawa, K., Wakino, S., Kimoto, M., Minakuchi, H., Fujimura, K., Hosoya, K., Komatsu, M., Kaneko, Y., Kanda, T., Tokuyama, H., Hayashi, K. & Itoh, H., 2013 Jun 1, In : FASEB Journal. 27, 6, p. 2301-2315 15 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2012

Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury

Tokuyama, H., Wakino, S., Hara, Y., Washida, N., Fujimura, K., Hosoya, K., Yoshioka, K., Hasegawa, K., Minakuchi, H., Homma, K., Hayashi, K. & Itoh, H., 2012 Aug 1, In : International Journal of Obesity. 36, 8, p. 1062-1071 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2011

Rho and Rho-kinase activity in adipocytes contributes to a vicious cycle in obesity that may involve mechanical stretch

Hara, Y., Wakino, S., Tanabe, Y., Saito, M., Tokuyama, H., Washida, N., Tatematsu, S., Yoshioka, K., Homma, K., Hasegawa, K., Minakuchi, H., Fujimura, K., Hosoya, K., Hayashi, K., Nakayama, K. & Itoh, H., 2011 Jan 25, In : Science Signaling. 4, 157, ra3.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis

Washida, N., Wakino, S., Tonozuka, Y., Homma, K., Tokuyama, H., Hara, Y., Hasegawa, K., Minakuchi, H., Fujimura, K., Hosoya, K., Hayashi, K. & Itoh, H., 2011 Sep 1, In : Nephrology Dialysis Transplantation. 26, 9, p. 2770-2779 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2010

Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function

Hasegawa, K., Wakino, S., Yoshioka, K., Tatematsu, S., Hara, Y., Minakuchi, H., Sueyasu, K., Washida, N., Tokuyama, H., Tzukerman, M., Skorecki, K., Hayashi, K. & Itoh, H., 2010 Apr 23, In : Journal of Biological Chemistry. 285, 17, p. 13045-13056 12 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)
2009

Clinical importance of Stenotrophomonas maltophilia nosocomial pneumonia due to its high mortality in hemodialysis patients

Wakino, S., Imai, E., Yoshioka, K., Kamayachi, T., Minakuchi, H., Hayashi, K., Inamoto, H. & Itoh, H., 2009 Jun 1, In : Therapeutic Apheresis and Dialysis. 13, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2008

A case of atypical POEMS syndrome without polyneuropathy

Morizane, R., Sasamura, H., Minakuchi, H., Takae, Y., Kikuchi, H., Yoshiya, N., Hashiguchi, A., Konishi, K., Okamoto, S. & Itoh, H., 2008 May 1, In : European Journal of Haematology. 80, 5, p. 452-455 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

Hasegawa, K., Wakino, S., Yoshioka, K., Tatematsu, S., Hara, Y., Minakuchi, H., Washida, N., Tokuyama, H., Hayashi, K. & Itoh, H., 2008 Jul 18, In : Biochemical and Biophysical Research Communications. 372, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)